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a computational approach for peptidomic analysis in taxonomic study of amphibian species.peptides in the skin secretion of frogs have been studied for some time now because they frequently possess important biological activity such as antibiotic, antimicrobial, or anticancer properties. in this paper, we present a computational approach for measuring the degree of similarity between the entire peptide complement of the skin secretion of specimens from the same or different species. the first step in the analysis is the generation of a mass spectral profile from an experimental high- ...200516220688
antimicrobial peptides from the skin secretions of the new world frogs lithobates capito and lithobates warszewitschii (ranidae).taxonomic revisions within the anuran family ranidae have established the genus lithobates that currently comprises 49 species of frogs from the new world. peptidomic analysis, using reversed-phase hplc with on-line detection by electrospray mass spectrometry, has led to the identification of multiple antimicrobial peptides in norepinephrine-stimulated skin secretions of the north american frog lithobates capito and the central american frog lithobates warszewitschii. structural characterization ...200919635516
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