| evaluation of several culture media for production of patulin by penicillium species. | the aim of this study was to evaluate different species of penicillium to identify those which have the potential to produce the greatest amount of the mycotoxin, patulin. additionally, six different culture media were compared to determine maximum patulin production. eleven different strains of penicillium species were selected because they had previously been reported to be producers of patulin. the strains included penicillium expansum, penicillium griseofulvum (formerly penicillium urticae), ... | 2005 | 15698685 |
| the sequence of the isoepoxydon dehydrogenase gene of the patulin biosynthetic pathway in penicillium species. | interest in species of the genus penicillium is related to their ability to produce the mycotoxin patulin and to cause spoilage of fruit products worldwide. the sequence of the isoepoxydon dehydrogenase (idh) gene, a gene in the patulin biosynthetic pathway, was determined for 28 strains representing 12 different penicillium species known to produce the mycotoxin patulin. isolates of penicillium carneum, penicillium clavigerum, penicillium concentricum, penicillium coprobium, penicillium dipodom ... | 2007 | 17043910 |
| characterization of two cytochrome p450 monooxygenase genes of the pyripyropene biosynthetic gene cluster from penicillium coprobium. | pyripyropenes are potent inhibitors of acyl-coa:cholesterol acyltransferase, which were initially discovered to be produced by aspergillus fumigatus. recently, penicillium coprobium pf1169 has also found to produce pyripyropene a (pya), which exhibits insecticidal properties. pyripyropenes are natural hybrid products of both terpenoid and polyketide origin. in our research, based on data generated using the genome sequencer flx for p. coprobium pf1169, we predicted the biosynthetic gene cluster ... | 2011 | 21224862 |
| characterization of two acetyltransferase genes in the pyripyropene biosynthetic gene cluster from penicillium coprobium. | pyripyropenes potently and selectively inhibit acyl-coa:cholesterol acyltransferase 2 (acat-2). among multiple isomers of pyripyropene (a to r), pyripyropene a (pya) has insecticidal properties in addition to its growth inhibition properties against human umbilical vein endothelial cells. based on the predicted biosynthetic gene cluster of pyripyropene a, two genes (ppb8 and ppb9) encoding two acetyltransferases (ats) were separately isolated and introduced into the model fungus aspergillus oryz ... | 2014 | 26019565 |