| evaluation of papillomaviruses associated with cyclosporine-induced hyperplastic verrucous lesions in dogs. | to determine whether cyclosporine a-induced hyperplastic skin lesions of dogs were associated with papillomavirus infections. | 2005 | 16273908 |
| canine inverted papillomas associated with dna of four different papillomaviruses. | inverted papillomas are uncommon papillomavirus (pv)-induced canine skin lesions. they consist of cup- to dome-shaped dermal nodules with a central pore filled with keratin. histologically they are characterized by endophytic projections of the epidermis extending into dermis. cytopathic effects of pvs infection include the presence of clumped keratohyalin granules, koilocytes and intranuclear inclusion bodies. different dna hybridization studies carried out with a canine oral papillomavirus (co ... | 2010 | 20042038 |
| keratinocyte antiviral response to poly(da:dt) stimulation and papillomavirus infection in a canine model of x-linked severe combined immunodeficiency. | x-linked severe combined immunodeficiency (xscid) is caused by a genetic mutation within the common gamma chain (γc), an essential component of the cytokine receptors for interleukin (il)-2, il-4, il-7, il-9, il-15, and il-21. xscid patients are most commonly treated with bone marrow transplants (bmt) to restore systemic immune function. however, bmt-xscid humans and dogs remain at an increased risk for development of cutaneous papillomavirus (pv) infections and their associated neoplasms, most ... | 2014 | 25025687 |
| canine keratinocytes upregulate type i interferons and proinflammatory cytokines in response to poly(da:dt) but not to canine papillomavirus. | papillomaviruses (pv) are double stranded (ds) dna viruses that infect epithelial cells within the skin or mucosa, most often causing benign neoplasms that spontaneously regress. the immune system plays a key role in the defense against pvs. since these viruses infect keratinocytes, we wanted to investigate the role of the keratinocyte in initiating an immune response to canine papillomavirus-2 (cpv-2) in the dog. keratinocytes express a variety of pattern recognition receptors (prr) to distingu ... | 2013 | 23557936 |