| hplc-spe-nmr identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus pestalotiopsis virgatula culture. | hplc-spe-nmr analysis of a crude extract of fermentation broth of cultured pestalotiopsis virgatula isolate tc-320 from terminalia chebula retz. (combretaceae) disclosed the presence of a simple but unprecedented low-molecular-weight metabolite, 9-hydroxybenzo[ c]oxepin-3[1 h]-one, subsequently isolated by a targeted purification procedure. | 2009 | 19609838 |
| virgatolides a-c, benzannulated spiroketals from the plant endophytic fungus pestalotiopsis virgatula. | virgatolides a-c (1-3), unique metabolites with a 3',4',5',6'-tetrahydrospiro[chroman-2,2'-pyran] core, were isolated from cultures of the plant endophytic fungus pestalotiopsis virgatula. compounds 1-3 possess two previously undescribed skeletons originating from a benzannulated 6,6-spiroketal and one (2 and 3) and two (1) γ-lactone units, respectively. the structure of 1 was secured by x-ray crystallography. | 2011 | 21495643 |
| Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study. | The endophytic fungus Pestalotiopsis virgatula, derived from the plant Terminalia chebula and previously found to produce a large excess of a single metabolite when grown in the minimal M1D medium, was induced to produce a variety of unusual metabolites by growing in potato dextrose broth medium. Analysis of the fermentation medium extract was performed using an HPLC-PDA-MS-SPE-NMR hyphenated system, which led to the identification of a total of eight metabolites (1-8), six of which are new. Mos ... | 2011 | 21942847 |