novel use of a n2-specific enzyme-linked immunosorbent assay for differentiation of infected from vaccinated animals (diva)-based identification of avian influenza. | proper vaccination with validated companion differentiation of infected from vaccinated animals (diva) tests using a vaccine containing a heterologous neuraminidase to the field virus can be effective to control avian influenza (ai). however, indirect immunofluorescent assay, the only field validated diva test, has limitations to be set up as high throughput screening test and the assay requires subjective interpretation of the results. to apply the diva strategy to the korean h9n2 low pathogeni ... | 2009 | 19446190 |
an outbreak of avian influenza subtype h9n8 among chickens in south korea. | low pathogenic avian influenza subtype h9n8 was diagnosed on a korean native chicken farm in gyeonggi province, south korea, in late april 2004. clinical signs included moderate respiratory distress, depression, mild diarrhoea, loss of appetite and a slightly elevated mortality (1.4% in 5 days). pathologically, mucopurulent tracheitis and air sacculitis were prominently found with urate renal deposition. the isolated a/chicken/kr/164/04 (h9n8) had an ala-ser-gly-arg (a/s/g/r) motif at the cleava ... | 2006 | 17121732 |
continuing evolution of h9 influenza viruses in korean poultry. | we analyzed the evolution of h9 influenza viruses isolated from korean chicken farms from 2002 to 2004. korean h9 viruses formed two antigenically distinct groups: those isolated from 1996 to mid-2003, and those isolated from late 2003 through 2004. most of the 2004 isolates showed greater cross-reactivity with the second group than with the first group. phylogenetic analysis of the 12 viruses studied revealed three genotypes of h9n2 viruses and showed that reassortment had occurred. one isolate ... | 2007 | 17056087 |