| an experimental study of the anti-hsv-ii action of 500 herbal drugs. | experimental assessments were made on the anti-hsv-ii action of 500 herbs by determinations of the virus inhibition logarithm (vil). 13 highly effective herbs (vil greater than or equal to 4.00) were screened cut, providing a rational basis for clinical therapy. among these effective herbs, 10 were aqueous extracts of artemisia anomala, centella asiatica, epimedium sagittatum, hibiscus mutabilis, hosta plantaginea, hypericum japonicum, inula japonica, mosla punctata, rhododendron simsii, and rhu ... | 1989 | 2550706 |
| xanthones from hypericum japonicum and h. henryi. | from the aerial part of hypericum japonicum, one new xanthone glycoside, 1,5-dihydroxyxanthone-6-o-beta-d-glucoside, one novel dimer xanthone, bijaponicaxanthone, and the first natural prenylated xanthone, 1,3,5,6-tetrahydroxy-4-prenylxanthone, were isolated together with the four known xanthones, 1,5,6-trihydroxyxanthone, isojacereubin, 6-deoxyisojacareubin and 4',5'-dihydro-1,5,6-trihydroxy-4',4',5'-trimethylfurano (2',3':4,5) xanthone. five previously known xanthones, kielcorin, cadensin, 1,7 ... | 1998 | 9842731 |
| [studies on the antilipid peroxidation of nine sorts of chinese herbal medicines with the function of protecting liver]. | the antilipid peroxidation of nine sorts of chinese herbal medicines with the function of protecting liver, including salivia miltiorrhiza, hypericum japonicum, scutellaria baicalensis, callicarpa cathayana, chrysanthemum indicum, paeonia latiflora, lysimachia christinae, ligustrum lucidum (l1), patrinia villosa (pv) on hepatic homogenate of rat were tested. it was found that all tested medicines showed inhibition with dose-effect relationship, the inhibitory rate of l1 and pv were lower than th ... | 1997 | 12572505 |
| hplc analysis and pharmacokinetic study of quercitrin and isoquercitrin in rat plasma after administration of hypericum japonicum thunb. extract. | a simple hplc method was developed for determination of quercitrin and isoquercitrin in rat plasma. reversed-phase hplc was employed for the quantitative analysis using kaempferol-3-o-beta-d-glucopyranoside-7-o-alpha-l-rhamnoside as an internal standard. following extraction from the plasma samples with ethyl acetate-isopropanol (95:5, v/v), these two compounds were successfully separated on a luna c(18) column (250 x 4.6 mm, 5 microm) with isocratic elution of acetonitrile-0.5% aqueous acetic a ... | 2008 | 18059045 |
| hepatoprotective effect of hypericum japonicum extract and its fractions. | to investigate the hepatoprotective activity of different parts of hypericum japonicum against carbon tetrachloride(ccl(4))-induced hepatitis and alpha-naphthyl-isothiocyanate (anit)-induced cholestasis. | 2008 | 18178045 |
| [effect of anti-influenza virus h3n2 of hypericum japonicum in vivo]. | to investigate anti-influenza virus h3n2 effect of hypericum japonicum in vivo. | 2008 | 18973021 |
| a new phloroglucinol diglycoside derivative from hypericum japonicum thunb. | a new phloroglucinol diglycoside 1, together with eight known compounds, were isolated from hypericum japonicum thunb. the structure of the new compound 1 was determined by spectroscopic methods to be 4,6-dimethyl-5-o-[alpha-l-rhamnopyranosyl-(1-->6)-alpha-d-glucopyranosyl] multifidol. different solvent extracts of hypericum japonicum thunb. were tested for in vivo antihypoxic activity using mice, with the etoac extract showing better activity. | 2008 | 19002080 |
| [content of rare earth elements in wild hypericum japonicum thunb]. | rare earth elements are important nutritional elements for human health, and today more and more attention has been paid to the effective components in chinese traditional medicine, especially to rare earth elements. fifteen rare earth elements in wild hypericum japonicum thunb were analyzed by the methods of icp-ms. the results showed that the concentrations of la, ce, pr, nd, sm, eu, gd, tb, dy, ho, er, yb, tm, lu and y ranged from 6 ng x g(-1) x dw to 14 522 ng x g(-1) x dw, and among them th ... | 2009 | 19810563 |
| filicinic acid based meroterpenoids with anti-epstein-barr virus activities from hypericum japonicum. | seven filicinic acid-based meroterpenoids (1-7), possessing 6/6/11, 6/6/7/5, or 6/6/10 ring systems, were isolated from hypericum japonicum. all of them have novel skeletons with the incorporation of sesquiterpenoid moieties to an acylated filicinic acid. compounds 2a and 4 exhibited significant efficacy on anti-epstein-barr virus, with ec50 values of 0.57 and 0.49 μm, respectively. furthermore, compounds 2a and 4 were well accommodated to the binding pocket of 2gv9 predicted by the molecular do ... | 2016 | 27116597 |
| two new bioactive α-pyrones from hypericum japonicum. | hypericum japonicum (guttiferae), a type of annual or perennial herb, has been historically applied to cure infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, and internal hemorrhage. in our successive studies on the genus hypericum, two new α-pyrones termed japopyrones a and b (1 and 2) were isolated from h. japonicum. their structures and absolute configurations were established by the comprehensive analyses of spectroscopic data, the application of the single-crysta ... | 2016 | 27104499 |
| isojacareubin from the chinese herb hypericum japonicum: potent antibacterial and synergistic effects on clinical methicillin-resistant staphylococcus aureus (mrsa). | through bioassay-guided fractionation of the extracts from the aerial parts of the chinese herb hypericum japonicum thunb. murray, isojacareubin (isj) was characterized as a potent antibacterial compound against the clinical methicillin-resistant staphylococcus aureus (mrsa). the broth microdilution assay was used to determine the minimal inhibitory concentrations (mics) and minimal bactericidal concentrations (mbcs) of isj alone. the results showed that its mics/mbcs ranged from 4/16 to 16/64 μ ... | 2012 | 22942699 |
| ethnobotanical study on medicinal plants used by local hoklos people on hainan island, china. | the aim of this study is to collect information on the use of medicinal plants by the local hoklos people on hainan island, and compare medicinal traditions in the study area with li medicines (lm) and traditional chinese medicines (tcm). | 2016 | 27444693 |
| the effect-enhancing and toxicity-reducing activity of hypericum japonicum thunb. extract in murine liver cancer chemotherapy. | chinese herbs are potential sources of antitumor drugs with immunoregulatory activity and few adverse effects. in the present study, we investigated whether the hypericum japonicum thunb. (hjt) extract enhanced the efficacy of 5-fluorouracil (5-fu) treatment in murine liver tumor xenografts and reduced toxicity of chemotherapy in hepatoma h22-bearing mice. tumor weight and inhibition rate, thymus and spleen indices, as well as white blood cell (wbc) count were calculated. the phagocytic function ... | 2013 | 24649182 |