two immunoregulatory peptides with antioxidant activity from tick salivary glands.ticks are blood-feeding arthropods that may secrete immunosuppressant molecules, which inhibit host inflammatory and immune responses and provide survival advantages to pathogens at tick bleeding sites in hosts. in the current work, two families of immunoregulatory peptides, hyalomin-a and -b, were first identified from salivary glands of hard tick hyalomma asiaticum asiaticum. three copies of hyalomin-a are encoded by an identical gene and released from the same protein precursor. both hyalomin ...201020178988
prevalence of ixodid ticks on cattle, sheep and goats in ilam county, ilam province, iran.this survey was performed to find out the infestation rate of ixodidae ticks in domestic ruminants in ilam county during 21 march 2009 to 23 august 2009. sampling was performed in 25 villages and 15 animal farm from different areas of this county. a total of 1,316 ticks were collected from 416 cattle, 208 sheep and 147 goats. the overall prevalence of ticks was recorded: 43, 23.5, and 49/6 % in cattle, sheep, and goats respectively. the number of ticks that collected from cattle, sheep, and goat ...201325698857
transcriptional activation of antioxidants may compensate for selenoprotein deficiencies in amblyomma maculatum (acari: ixodidae) injected with selk- or selm-dsrna.the gulf-coast tick, amblyomma maculatum, possesses an elaborate set of selenoproteins, which prevent the deleterious effects from oxidative stress that would otherwise occur during feeding. in the current work, we examined the role of selenoprotein k (selk) and selenoprotein m (selm) in feeding a. maculatum by bioinformatics, transcriptional gene expression, rna interference and antioxidant assays. the transcriptional expression of selk did not vary significantly in salivary glands or midguts t ...201424698418
ticks and tick-borne pathogens at the cutaneous interface: host defenses, tick countermeasures, and a suitable environment for pathogen establishment.ticks are unique among hematophagous arthropods by continuous attachment to host skin and blood feeding for days; complexity and diversity of biologically active molecules differentially expressed in saliva of tick species; their ability to modulate the host defenses of pain and itch, hemostasis, inflammation, innate and adaptive immunity, and wound healing; and, the diverse array of infectious agents they transmit. all of these interactions occur at the cutaneous interface in a complex sequence ...201324312085
knockdown of selenocysteine-specific elongation factor in amblyomma maculatum alters the pathogen burden of rickettsia parkeri with epigenetic control by the sin3 histone deacetylase corepressor complex.selenocysteine is the 21st naturally-occurring amino acid. selenoproteins have diverse functions and many remain uncharacterized, but they are typically associated with antioxidant activity. the incorporation of selenocysteine into the nascent polypeptide chain recodes the tga stop codon and this process depends upon a number of essential factors including the selenocysteine elongation factor (sef). the transcriptional expression of sef did not change significantly in tick midguts throughout the ...201324282621
identification of 24h ixodes scapularis immunogenic tick saliva proteins.ixodes scapularis is arguably the most medically important tick species in the united states. this tick transmits 5 of the 14 human tick-borne disease (tbd) agents in the usa: borrelia burgdorferi, anaplasma phagocytophilum, b. miyamotoi, babesia microti, and powassan virus disease. except for the powassan virus disease, i. scapularis-vectored tbd agents require more than 24h post attachment to be transmitted. this study describes identification of 24h immunogenic i. scapularis tick saliva prote ...201525825233
tick salivary compounds: their role in modulation of host defences and pathogen transmission.ticks require blood meal to complete development and reproduction. multifunctional tick salivary glands play a pivotal role in tick feeding and transmission of pathogens. tick salivary molecules injected into the host modulate host defence responses to the benefit of the feeding ticks. to colonize tick organs, tick-borne microorganisms must overcome several barriers, i.e., tick gut membrane, tick immunity, and moulting. tick-borne pathogens co-evolved with their vectors and hosts and developed m ...201323971008
[classification and diversity of tick community in tarim basin].to investigate the distribution pattern and structural characteristics of tick community and to understand the diversity of the communities in tarim basin.200617366967
salivating for knowledge: potential pharmacological agents in tick saliva. 200818271624
prevalence of ixodid ticks on cattle and sheep southeast of iran.a survey was carried out to investigate the prevalence of hard tick species (acari: ixodidae) on cattle and sheep southeast of iran. a total of 972 ticks were collected from 280 infested cattle and 1,207 ticks were collected from 632 infested sheep during activating seasons of ticks in 2008-2009. the species collected from cattle were hyalomma marginatum marginatum (50.92%), hyalomma anatolicum excavatum (25.61%), hyalomma anatolicum anatolicum (8.12%), hyalomma asiaticum asiaticum (1.85%), and ...201021113660
virus "tamdy"--a new arbovirus, isolated in the uzbee s.s.r. and turkmen s.s.r. from ticks hyalomma asiaticum asiaticum schulee et schlottke, 1929, and hyalomma plumbeum plumbeum panzer, 1796.eleven virus strains were isolated from ticks hyalomma asiaticum asiaticum schulce et schlottke, 1929, and hyalomma plumbeum plumbeum panzer, 1796,collected in 1971-1974 in desert regions of the uzbee s.s.r. and the turkmen s.s.r. according to cf test the strains were closely related to each other and not antigenically connected with viruses from antigenic groups a, b, california, chf-congo, bakau, bunyamwera, gajam, kaisodi, qalyub, kemerovo, quaranfil, simbu, turlock, hughes, uukuniemi, tete a ...1976134682
[isolation of borrelia burgdorferi in ixodes from four counties, in north xinjiang].to identify ticks and determine the borrelia (b.) burgdorferi genotype from four counties of northern xinjiang.201424831623
[characteristics of acquired resistance of lambs to mature ticks hyalomma asiaticum asiaticum (experimental studies)].a new method was employed for studies of parasite-host relationships between ixodid ticks and their hosts. it has been established that ixodid ticks are able to desensibilize the reactive sensibility of the host and to satiate themselves without unhibiting the latter. every day and long parasitism of the ticks on cattle (in nature) and increasing doses of secretion of the ticks' saliva (sensibilizer) lead apparently to the weakening of the host's organism (desensitization). however, under labora ...19761023144
a new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china.crimean-congo hemorrhagic fever virus (cchfv) is a highly pathogenic tick-borne virus with a fatality rate of up to 50% in humans. cchfv is widely distributed in countries around the world. outbreaks of cchfv infection in humans have occurred in prior years in xinjiang province, china. epidemiological surveys have detected cchfv rna in ticks and animals; however, few isolates were identified. in this study, we identified and isolated a new cchfv strain from hyalomma asiaticum asiaticum ticks col ...201728251517
coevolutionary analyses of the relationships between piroplasmids and their hard tick coevolution is a key driver of biological diversity. to examine the evolutionary relationships between piroplasmids and their hard tick hosts, we calculated the molecular clock and conducted phylogenetic analyses of both groups. based on our results, we conclude that the divergence time of piroplasmids (∼56 mya) is later than divergence time of their hard tick hosts (∼86 mya). from analyses of the evolution of both piroplasmid and vector lineages and their association, we know that ...201324101988
[taxonomy of previously unclassified tamdy virus (tamv) (bunyaviridae, nairovirus) isolated from the hyalomma asiaticum asiaticum schülce et schlottke, 1929 (ixodidae, hyalomminae) in the middle east and transcaucasia].complete genome sequencing of three tamdy (tamv) virus strains was carried out. the prototype strain tamv/leiv-1308uz was isolated for the very first time from the hyalomma asiaticum asiaticum schülce et schlottke, 1929 (ixodidae, hyalomminae) collected in the august 1971 from sheep in the arid area near namdybulak town (41 degrees 36' n, 64 degrees 39' e) in the tamdinsky district of the bukhara region (uzbekistan). tamv was revealed to be a prototype member of the new phylogenetic group within ...201625069280
[duration of the developmental cycle of hyalomma asiaticum asiaticum schulze et schlottke in natural biotopes]. 19724263900
hyalomma asiaticum asiaticum schülze and schlottke, 1929. its distribution, hosts, seasonal activity, life cycle, and role in transmission of bovine theileriosis in iran. 19685693626
[visual potentialities of the tick hyalomma asiaticum asiaticum (ixodidae)].ethological experiments with the desert tick hyalomma asiaticum asiaticum are conducted. it is shown that tick inhabiting open landscapes discovers his host using his eyes. since the eyes of this species have a poor resolving possibility, black objects with white strips drawn on it are less attractive for the tick. when the tick scans an area looking for host, the principal optical axis of his eyes is directed not higher than 20 degrees. in allows the tick to discover objects having angular size ...200816033221
a tick b-cell inhibitory protein from salivary glands of the hard tick, hyalomma asiaticum asiaticum.some studies done to date suggest that b-cell inhibitory factor occurred in tick saliva. in this study, a novel protein having b-cell inhibitory activity was purified and characterized from the salivary glands of the hard tick, hyalomma asiaticum asiaticum. this protein was named b-cell inhibitory factor (bif). the cdna encoding bif was cloned by cdna library screening. the predicted protein from the cdna sequence is composed of 138 amino acids including the mature bif. no similarity was found b ...200616554026
survey on infection rate, vectors and molecular identification of theileria annulata in cattle from north west, iran.tropical theileriosis is a progressive bovine lymphoproliferative disease caused by the intracellular protozoan parasite theileria annulata. in this study 138 blood samples and 289 ticks were collected and examined from cattle that belonged to 10 randomly selected flocks. the tbs-s/tbs-a primer set was used for pcr amplification of theileria spp. and the ta-s/tbs-a specific primer set was used in semi-nested pcr technique for detection of t. annulata. blood smears of each case were examined by g ...201627605839
Displaying items 1 - 21 of 21