| [effect of fu-zheng qu-xie on gastric disease infected with campylobacter pyloridis]. | chinese herbal medicine and gentamycin were used separately in the treatment of 75 cases of gastric disease by campylobacter pyloridis (cp). surveying the changes of the gastrofiberscope, pathological test, bacteriology and immunology. this study, found that in the chinese herbal medicine group clinical symptoms were obviously improving the effective rate for cp being 80% (24/30), the death rate for cp 30% (9/30), and the effective rate for patho-histological changes 50% (15/30). differences of ... | 1991 | 2065393 |
| [the experimental research of atractylodes macrocephala and poria cocos on the meridian tropism theory in animals]. | the research was designed to study the meridian tropism theory of traditional chinese drug through experiments in animals. | 2004 | 15656143 |
| anti-inflammatory components isolated from atractylodes macrocephala koidz. | the petroleum ether-ether (1 : 1) extract of atractylodis macrocephalae was screened by cell membrane chromatography (cmc) and subsequently separated by column chromatography (cc) and high performance liquid chromatography (hplc). five components were isolated and identified as atractylenolide iii 1, atractylenolide i 2, 14-acetoxy-12-senecioyloxytetradeca-2e,8e,10e-trien-4,6-diyn-1-ol 3, 14-acetoxy-12-alpha-methylbutyl-2e,8e,10e-trien-4,6-diyn-1-ol 4 and 14-acetoxy-12-beta-methylbutyl-2e,8e,10e ... | 2008 | 19023804 |
| [screening study of the kinetogenic effects of serum containing four chinese materia medicas on the colonic smooth muscle cells in rats]. | to study the kinetogenic effects of serum containing semen arecae, dandelion, semen raphaniand atractylodes macrocephala on the colonic smooth muscle cells of rats. | 2009 | 19673333 |
| screening anti-inflammatory components from chinese traditional medicines using a peritoneal macrophage/cell membrane chromatography-offline-gc/ms method. | we report the development of an analytical method combining cell membrane chromatography (cmc) with gas chromatography/mass spectrometry (gc/ms). this was applied to the purification and identification of anti-inflammatory components from traditional chinese medicines. the stationary phase of the cmc employed mouse peritoneal macrophage (pm) cell membranes. we investigated the performance of the pm/cmc-offline-gc/ms method using hydrocortisone (hc) and dexamethasone (dm) as standards. the method ... | 2009 | 19664972 |
| [professor ling changquan's experience in treating primary liver cancer: an analysis of herbal medication]. | on the basis of outpatients' medical records concerning primary liver cancer (plc), data of 552 patients (with 2020 effective prescriptions) from the outpatient department of changhai hospital treated by professor ling changquan were collected. the nature, flavor and meridian distribution of the herbs used in the prescriptions were summarized by frequency method, and the features of the herbs used according to syndrome differentiation were analyzed by logistic regression. the couple herbs used w ... | 2008 | 19063833 |
| [effects of atractylodes macrocephala monosaccharide composition on cytodifferentiation and villin expression of iec-6 cells in vitro]. | to study the influence of atractylodes macrocephala monosaccharide composition (ammc) on iec-6 cells by observing cytodifferentiation and expression of villin. | 2010 | 21049619 |
| an antioxidant phytotherapy to rescue neuronal oxidative stress. | oxidative stress is involved in the pathogenesis of ischemic neuronal injury. a chinese herbal formula composed of poria cocos (chinese name: fu ling), atractylodes macrocephala (chinese name: bai zhu) and angelica sinensis (chinese names: danggui, dong quai, donggui; korean name: danggwi) (fbd), has been proved to be beneficial in the treatment of cerebral ischemia/reperfusion (i/r).this study was carried out to evaluate the protective effect of fbd against neuronal oxidative stress in vivo and ... | 2008 | 18955358 |
| herbal formula fbd extracts prevented brain injury and inflammation induced by cerebral ischemia-reperfusion. | the aim of this work was to verify neuroprotective and anti-inflammatory properties of fbd, a herbal formula composed of poria cocos, atractylodes macrocephala and angelica sinensis, in icr mice subjected to repetitive 10 min of common carotid arteries occlusion followed 24 h reperfusion. intragastrical pretreatment with supercritical carbon dioxide extract (fbd-co(2), 37.5 mg/kg) twice daily for 3.5 d, significantly reduced evans blue influx, neuron specific enolase (nse) efflux, brain infarcti ... | 2008 | 18486376 |
| effects of atractylodes macrocephala on the cytomembrane ca2+-activated k+ currents in cells of human pregnant myometrial smooth muscles. | the study examined the inhibitory effect of atractylodes macrocephala (am) on the uterine contraction during premature delivery and explored its electrophysiological mechanism by studying the effects of am on the ca(2+)-activated k(+) currents of pregnant human myometrial smooth muscle cells with or without the treatment with interleukin-6. single cells were acutely isolated from pregnant human myometrial smooth muscles. whole-cell ca(2+)-activated k(+) currents were recorded by using an axopatc ... | 2008 | 18480998 |
| effects of atractylodes macrocephala koidzumi rhizome on 3t3-l1 adipogenesis and an animal model of obesity. | ethnopharmacological relevance: atractylodes macrocephala koidzumi (amk) is an herbal medicine traditionally used for treatment of abdominal pain, gastrointestinal disease, obesity, and related complications. aim of the study: we investigated the effects and molecular mechanism of amk rhizome water extract on 3t3-l1 adipogenesis and an animal model of obesity. | 2011 | 21669278 |
| screening for the anti-inflammatory activity of fractions and compounds from atractylodes macrocephala koidz. | the aim of this study was to screen for the anti-inflammatory activity of fractions and compounds from atractylodes macrocephala koidz. the rhizomes of atractylodes macrocephala were treated with supercritical co(2) fluid and the extract was separated by normal-phase and reverse-phase column chromatography. the separated samples were screened with white blood cell membrane (wbcm) chromatography (wbcm-c). the anti-inflammatory effects of these fractions and components were tested pharmacologicall ... | 2007 | 17869038 |
| toxicity of atractylon and atractylenolide iii identified in atractylodes ovata rhizome to dermatophagoides farinae and dermatophagoides pteronyssinus. | the acaricidal activity of materials derived from rhizome of atractylodes ovata (atractylodes macrocephala) toward adult dermatophagoides farinae and dermatophagoides pteronyssinus was examined using fabric-circle residual contact and vapor-phase toxicity bioassays. results were compared with those of the currently used acaricides: benzyl benzoate, dibutyl phthalate, and n,n-diethyl-m-toluamide (deet). the active principles of a. ovata rhizome were identified as the sesquiterpenoids, atractyleno ... | 2007 | 17595110 |
| gaba(a) receptor modulators from chinese herbal medicines traditionally applied against insomnia and anxiety. | several chinese herbal medicines (chms) are used in the treatment of insomnia, restlessness, or anxiety. however, mechanisms underlying this effect and scientific proof for their traditional use is scarce. in the present study chms were screened for their ability to modulate gaba-induced chloride currents (i(gaba)), and active principles were isolated thus providing scientific evidence for their use as sedative and/or anxiolytic agents in cm. herbal drugs were extracted successively with petrole ... | 2011 | 22118921 |
| comparative genome analyses of serratia marcescens fs14 reveals its high antagonistic potential. | s. marcescens fs14 was isolated from an atractylodes macrocephala koidz plant that was infected by fusarium oxysporum and showed symptoms of root rot. with the completion of the genome sequence of fs14, the first comprehensive comparative-genomic analysis of the serratia genus was performed. pan-genome and cog analyses showed that the majority of the conserved core genes are involved in basic cellular functions, while genomic factors such as prophages contribute considerably to genome diversity. ... | 2015 | 25856195 |
| atractylenolide i and atractylenolide iii inhibit lipopolysaccharide-induced tnf-alpha and no production in macrophages. | in order to clarify the mechanism involved in the antiinflammatory activity of atractylenolide i and atractylenolide iii from the rhizomes of atractylodes macrocephala koidz, their effects on tumor necrosis factor-alpha (tnf-alpha) and nitric oxide (no) production in peritoneal macrophages were examined. atractylenolide i and atractylenolide iii decreased the tnf-alpha level in lps-stimulated peritoneal macrophages in a dose-dependent manner, their ic(50) values were 23.1 microm and 56.3 microm, ... | 2007 | 17221938 |
| stimulating effects on mouse splenocytes of glycoproteins from the herbal medicine atractylodes macrocephala koidz. | a traditional herbal medicine, atractylodes macrocephala koidz. (amk), has long been used as a digestive and tonic. recent investigations have suggested its potential ability in stimulating immune responses, although a scientific basis for this activity has not yet been elucidated. based on previous results showing that the activity might be due to proteins, we purified protein samples from an original sample preparation of amk and examined the stimulating ability of the protein samples on mouse ... | 2007 | 17084605 |
| establishment of the model of white blood cell membrane chromatography and screening of antagonizing tlr4 receptor component from atractylodes macrocephala koidz. | a model of white blood cell membrane chromatography (wb-cmc) was established to screen active component from atractylodes macrocephala koidz. the component can antagonize toll-like receptor 4 (tlr4) and inhibit inflammatory reaction. in the model of wb-cmc, cell membrane stationary phase (cmsp) was prepared by immobilizing the rabbit white blood cell membrane (wbcm) onto the surface of silica carrier and taxinol was used as a model molecule. the active component which can act on wbcm and its rec ... | 2006 | 16704122 |
| chemical investigation on sijunzi decoction and its two major herbs panax ginseng and glycyrrhiza uralensis by lc/ms/ms. | sijunzi decoction consists of panax ginseng, poria cocos, atractylodes macrocephala and glycyrrhiza uralensis. high performance liquid chromatography coupled with tandem mass spectrometry (lc/ms(n)) was applied to identify and characterize three types of active components, ginsenoside (from p. ginseng), flavonoid and triterpenoid (from g. uralensis) in sijunzi decoction. spectra of ms and ms/ms from [m+na](+) ions of ginsenosides were acquired and interpreted for their identification. fragmentat ... | 2006 | 16574366 |
| neuroprotective effect of a chuk-me-sun-dan on neurons from ischemic damage and neuronal cell toxicity. | chukmesundan (cmsd), composed of the following 8 medicinal herbs including panex ginseng c.a. meyer, atractylodes macrocephala koid, poria cocos wolf, pinellia ternata breit, brassica alba boiss, aconitum carmichaeli debx, cynanchum atratum bge and cuscuta chinensis lam. cmsd is being used in korea for the treatment of various symptoms accompanying hypertension and cerebrovascular disorders. this study was carried out to examine the effects of cmsd on cultured primary neuron cell, cell cytotoxic ... | 2006 | 16474991 |
| quantitative determination of atractylenolide iii in rat plasma by liquid chromatography electrospray ionization mass spectrometry. | atractylenolide iii is a major active component in atractylodes macrocephala. this paper describes a simple, rapid, specific and sensitive method for the quantification of atractylenolide iii in rat plasma using a liquid-liquid extraction procedure followed by liquid chromatography mass spectrometric (lc-ms) analysis. a kromasil 3.5 microm c(18) column (150 mm x 2.00 mm) was used as the analytical column. linear detection responses were obtained for atractylenolide iii concentration ranging from ... | 2006 | 16324894 |
| neuroprotective effect of chuk-me-sun-dan on nmda- and ampa-evoked nitric oxide synthase activity in mouse brain. | chukmesundan (cmsd) is composed of 8 medicinal herbs including panex ginseng c.a. meyer, atractylodes macrocephala koid, poria cocos wolf, pinellia ternata breit, brassica alba boiss, aconitum carmichaeli debx, cynanchum atratum bge, and cuscuta chinensis lam and used for the treatment of various symptoms accompanying hypertension and cerebrovascular disorders. this study was carried out to examine the effects of cmsd on n-methyl-d-aspartate (nmda)-evoked, and alpha-amino-3-hydroxy-5-methyl-4-is ... | 2005 | 16237959 |
| suppression of th2-type immune response-mediated allergic diarrhea following oral administration of traditional korean medicine: atractylodes macrocephala koidz. | atractylodes macrocephala koidz (amk) is well-known as a digestive and tonic material and is widely used in traditional korean herbal medicines. previously, we found that protein samples obtained from the medicines could induce a preferential stimulation of type 1, rather than type 2, helper t lymphocytes (th) immune responses in vitro. since immune response induction is controlled by the balanced activation between th1- and th2-type immune responses, we tested to see whether or not the amk prot ... | 2005 | 16114514 |
| reactive oxygen species mediation of baizhu-induced apoptosis in human leukemia cells. | baizhu (atractylodes macrocephala koidz) has traditionally been used as an important ingredient of several chinese herbal medicines, which have been used for abdominal pain and gastroenterology diseases for thousands of years. despite its popularity in herbal therapies, little is known about the anticancer effect of baizhu. in this study, the anticancer potential of baizhu on human hepatoma and leukemia cell lines was evaluated. baizhu methanol extract induced apoptosis in human lymphoma jurkat ... | 2004 | 15652270 |
| influence of traditional chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. | the enzymes 5-lipoxygenase and elastase are therapeutic targets in dermatological disorders such as psoriasis. fifteen extracts from traditional chinese medicinal plants used to treat topical inflammations were screened for their inhibitory effect on lipoxygenase, cyclooxygenase and elastase activity in intact leukocytes and platelets. astragalus membranaceus, forsythia suspensa and poria cocos inhibited 5-lipoxygenase, with ic50 values of 141, 80 and 141 microg ml(-1), respectively. the latter ... | 2003 | 14604471 |
| [studies on physico-chemical properties and hypoglycemic activity of complex polysaccharide amp-b from atractylodes macrocephala koidz]. | to isolate a complex polysaccharide (amp-b) from atractylodes macrocephala koidz and study its phtsico-chemical properties and hypoglycemic activity. | 2003 | 14513804 |
| [gastrointestinal inhibitory effects of sesquiterpene lactones from atractylodes macrocephala]. | atractylenolide i (8,9-dehydroasterolide, b), 4,15-epoxy-8 beta-hydroxyasterolide (c) and atractylenolide iii (8 beta-hydroasterolide, d) from atractylodes macrocephala koidz, 28.0, 56.0 mumol/l, inhibited the spontaneous movement of rat isolated ileum with contractile force decreased obviously (p < 0.001), but the rest force not affected (p > 0.05). b, c and d inhibited the spasm enhanced by ach and his to rat ileum, rightly shifted the dose-response curves and reduced the maximal response (p < ... | 1999 | 12571906 |
| antagonistic effects of 3 sesquiterpene lactones from atractylodes macrocephala koidz on rat uterine contraction in vitro. | to study the effects of three sesquiterpene lactones: atractylenolide i (8,9-dehydroasterolide, b), 4,15-epoxy-8 beta-hydroxyasterolide (c), and atractylenolide iii (8 beta-hydroasterolide, d) from atractylodes macrocephala koidz, on rat isolated uterus smooth muscle. | 2000 | 11263255 |
| [a clinical study on the treatment of acute upper digestive tract hemorrhage with wen-she decoction]. | this paper deals with the prospective clinical study on treatment of acute upper digestive tract hemorrhage with wen-she decoction (wsd). an opened sequential controlled trial method of simple orientation quality reaction was adopted in this study. 7 cases were treated and all of them were cured. it was concluded that wsd was an excellent therapy to treat the middle or small amount hemorrhage of acute upper digestive tract. the effective rate of wsd of the stool ob (+) becoming (-) within 5 days ... | 1989 | 2766422 |
| shi-quan-da-bu-tang (ten significant tonic decoction), sqt. a potent chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs. | shi-quan-da-bu-tang (ten significant tonic decoction), or sqt (juzentaihoto, tj-48) was formulated by taiping hui-min ju (public welfare pharmacy bureau) in chinese song dynasty in ad 1200. it is prepared by extracting a mixture of ten medical herbs (rehmannia glutinosa, paeonia lactiflora, liqusticum wallichii, angelica sinesis, glycyrrhiza uralensis, poria cocos, atractylodes macrocephala, panax ginseng. astragalus membranaceus and cinnamomum cassia) that tone the blood and vital energy, and s ... | 1992 | 1294861 |
| metabolomics study on the anti-depression effect of xiaoyaosan on rat model of chronic unpredictable mild stress. | ethnopharmacology: xiaoyaosan, a famous chinese prescription, composed of poria (poria cocos (schw.) wolf), radix paeoniae alba (paeonia lactiflora pall.), radix glycyrrhizae (glycyrrhiza uralensis fisch.), radix bupleuri (bupleurum chinense dc.), radix angelicae sinensis (angelica sinensis (oliv.) diels), rhizoma atractylodis macrocephalae (atractylodes macrocephala koidz.), herba menthae (mentha haplocalyx briq.), and rhizoma zingiberis recens (zingiber officinale rosc.), has been widely used ... | 2010 | 20079416 |
| [the immunomodulatory effects of sijunzi decoction and its disassembled prescription on d-galactose-induced aging mice]. | to observe the immunomodulatory effects of codonopsis, atractylodes macrocephala, tuceahoe, broiled licorice and sijunzi decoction on d-galactose-induced aging mice. | 2009 | 20034224 |
| drug-use pattern of chinese herbal medicines in insomnia: a 4-year survey in taiwan. | insomnia is a common complaint in the general population. interest in the use of alternative treatments for insomnia is increasing exponentially and is fairly common in taiwan. we undertook a survey to define the drug utilization patterns of chinese herbal medicines (cm) for insomnia in taiwan. | 2009 | 19753680 |
| effects on neuroendocrinoimmune network of lizhong pill in the reserpine induced rats with spleen deficiency in traditional chinese medicine. | lizhong pill, composed of radix ginseng (panax ginseng c.a. meyer), rhizoma zingiberis (zingiber officinale roscoe), rhizoma atractylodis macrocephalae (atractylodes macrocephala koidz.) and radix glycytthizae (glycyrrhiza uralensis fisch.), is a classical herbal product for curing spleen deficiency in traditional chinese medicine (tcm), and reserpine treated rats show similar signs to tcm spleen deficiency pattern. this paper is aimed to explore the regulatory effect on neuroendocrinoimmune net ... | 2010 | 20951788 |
| identification of novel pregnane x receptor activators from traditional chinese medicines. | to investigate the ability of traditional chinese medicines (tcms) and their bioactive compounds to activate pregnane x receptor (pxr) signalling pathway. | 2011 | 21524698 |
| effects of dietary supplementation of chinese medicinal herbs on polymorphonuclear neutrophil immune activity and small intestinal morphology in weanling pigs. | the purpose of this study was to evaluate the effects of dietary chinese medicinal herbs (cmh) supplementation composed of panax ginseng, dioscoreaceae opposite, atractylodes macrocephala, glycyrrhiza uralensis, ziziphus jujube and platycodon grandiflorum, on the performance, intestinal tract morphology and immune activity in weanling pigs. two hundred and forty weaned pigs were assigned randomly to four dietary groups including the negative control (basal diet), 0.1% cmh, 0.3% cmh and 0.114% an ... | 2011 | 21535231 |
| protective effects of atractylodes macrocephala polysaccharide on liver ischemia-reperfusion injury and its possible mechanism in rats. | atractylodes macrocephala polysaccharide (amp), a traditional chinese medicine, is thought to have protective effects against liver injury. therefore, this study was designed to explore the effects of amp on hepatic ischemia-reperfusion injury (iri) and elucidate the possible mechanisms. ninety-six sprague-dawley rats were randomly divided into four groups with 24 rats per group: a normal control group, an iri group, an amp-treated group (0.4 g/kg/d) and a bifendate-treated group (100 mg/kg). ra ... | 2011 | 21598417 |
| evaluation of antidiabetic potential of selected traditional chinese medicines in stz-induced diabetic mice. | aims: traditional chinese medicine (tcm) has been used for treating complex chronic diseases owing to their fewer side-effects, better patient tolerance and relatively less cost. the present work was carried out to study the anti-diabetic efficacy and mechanisms of 34 tcms. materials and methods: streptozotocin (stz)-diabetic mice were orally administrated with corresponding herbal solution once a day for 4 weeks. at the end of experiment, the level of plasma glucose, malondialdehyde (mda), the ... | 2011 | 21798327 |
| metabonomic study on chronic unpredictable mild stress and intervention effects of xiaoyaosan in rats using gas chromatography coupled with mass spectrometry. | ethnopharmacology: xiaoyaosan (xys), a famous chinese prescription, composed of radix bupleuri (bupleurum chinense dc.), radix angelicae sinensis (angelica sinensis (oliv.) diels), radix paeoniae alba (paeonia lactiflora pall.), rhizoma atractylodis macrocephalae (atractylodes macrocephala koidz.), poria (poria cocos (schw.) wolf), radix glycyrrhizae (glycyrrhiza uralensis fisch.), herba menthae (mentha haplocalyx briq.), and rhizoma zingiberis recens (zingiber officinale rosc.), has been widely ... | 2011 | 21718771 |
| [molecular identification and sequence analysis of broad bean wilt virus 2 isolates from atractylodes macrocephala koidz]. | to identity the pathogen that causes the mosaic and yellowing symptoms on atractylodes macrocephala koidz in jiangxian, shanxi province, biological inoculation, sequence-independent amplification (sia),rt-pcr and other identification methods were used. the results showed that the chlorotic and necrosis symptoms occurred in the indicator plant chenopodium quinoa after it was infected with the pathogen,and the same symptoms appeared after the reinoculation of healthy atractylodes macrocephala koid ... | 2015 | 25997332 |
| anti‑inflammatory and antioxidant activity of the traditional herbal formula gwakhyangjeonggi‑san via enhancement of heme oxygenase‑1 expression in raw264.7 macrophages. | gwakhyangjeonggi‑san (ghjgs) is a mixture of herbal plants, including agastache rugosa, perilla frutescens, angelica dahurica, areca catechu, poria cocos, magnolia officinalis, atractylodes macrocephala, citrus reticulata, pinellia ternata, platycodon grandiflorum, glycyrrhiza uralensis, ziziphus jujuba and zingiber officinale. ghjgs has been used for treating diarrhea‑predominant irritable bowel syndrome in traditional korean medicine. in the present study, the anti‑inflammatory and antioxidant ... | 2016 | 27052497 |
| molecular screening of chinese medicinal plants for progestogenic and anti-progestogenic activity. | estrogen and progestins have adverse effects, and many of these adverse effects are caused by progestins. due to this, many women choose to use botanical alternatives for hormone replacement therapy, which does not trigger steroidogenic properties. therefore, it is necessary to screen these herbs for progestogenic and anti-progestogenic properties. extract of 13 chinese medicinal plants were analysed for progestogenic and anti-progestogenic activities by using progesterone response element-drive ... | 2014 | 24845509 |
| post-hematopoietic stem cell transplantation in patients with hematologic disorders: chinese herbal medicine for an unmet need. | while much progress has been made in the field of hematopoietic stem cell transplantation (hsct), headway in the promotion of recovery following this procedure has been limited. data regarding the potential of chinese herbal medicine (chm) for patients with hematologic disorders who received hsct are gradually increasing; however, these data are mostly in chinese. therefore, we set out to summarize the existing data. we searched pubmed, the cochrane library and the china national knowledge infra ... | 2016 | 27641605 |
| integrative medicine for relief of nausea and vomiting in the treatment of colorectal cancer using oxaliplatin-based chemotherapy: a systematic review and meta-analysis. | the management of chemotherapy-induced nausea and vomiting (cinv) remains an issue in the treatment of colorectal cancer using oxaliplatin-based regimens. certain traditional plant-based medicines (tms) have histories of use for nausea and vomiting and have been integrated with conventional therapies for cinv. to assess the effectiveness of integrative management of cinv, meta-analysis was conducted of 27 randomised controlled studies (1843 participants) published from 2005 to 2013. the oxalipla ... | 2016 | 26912094 |
| pharmacokinetic interaction of astragaloside iv with atractylenolide i and prim-o-glucosylcimifugin in male sprague dawley rats. | astragaloside iv, atractylenolide i, and prim-o-glucosylcimifugin are main medicinal components of the traditional chinese medicine prescription yu-ping-feng which is composed of three herbs: astragalus membranaceus, atractylodes macrocephala, and saposhnikovia divaricata. this study is aimed to assess the influence of atractylenolide i and prim-o-glucosylcimifugin on the pharmacokinetic profile of astragaloside iv so as to investigate the pharmacokinetic mechanisms of the yu-ping-feng prescript ... | 2014 | 24452462 |
| folfox 4 combined with herbal medicine for advanced colorectal cancer: a systematic review. | this systematic review evaluates the clinical evidence for the addition of herbal medicines (hms) to folfox 4 for advanced colorectal cancer (acrc) in terms of tumor response rate (trr), survival, quality of life and reduction in adverse events (aes). seven electronic databases were searched for randomized controlled trials (rcts) of folfox4 combined with hms compared to folfox4 alone. outcome data for 13 randomized controlled trials were analysed using review manager 5.1. risk of bias for objec ... | 2014 | 24343974 |
| chemical composition and synergistic antioxidant activities of essential oils from atractylodes macrocephala and astragalus membranaceus. | chemical composition of the essential oils derived from atractylodes macrocephala (ama), astragalus membranaceus (ame) and ama-ame herb pair was investigated using gas chromatography-mass spectrometry (gc-ms). antioxidant activities were evaluated by 1,1-diphenyl-2-picyrlhydrazyl (dpph) radical-scavenging and trolox equivalent antioxidant capacity (teac) assays. forty-five, ten and forty-three components were identified in ama, ame and ama-ame essential oils, respectively. ama-ame essential oil ... | 2013 | 24273876 |
| a stable fixed-dose combination tablet of pseudoephedrine and kob extracts for the extended release. | allergic rhinitis (ar) is characterized by inflammation of the nasal mucosa with hypersensitivity resulting from seasonal or perennial responses to specific environmental allergens and by symptoms like nasal rubbing, sneezing, rhinorrhea, lacrimation, nasal congestion and obstruction, and less frequently cough. kob extracts, which is a polyherbal medicine consisting of 5 different herbs (atractylodes macrocephala, astragalus membranaceus, saposhnikovia divaricata, ostericum koreanum and scutella ... | 2013 | 23780499 |
| anti-inflammatory and immunoregulatory effects of yupingfeng powder on chronic bronchitis rats. | to investigate the anti-inflammatory and immunoregulatory effects of yupingfeng (, ypf) powder and its components in rats. | 2013 | 23504545 |
| synergistic antioxidant activities of eight traditional chinese herb pairs. | many chinese therapeutic herbs that are traditionally used in combination demonstrate significantly better pharmacological effects when used in the combination than when used alone. however, the pharmacological mechanism for this synergism is still not well understood. in the present study, the antioxidant activities of six herbs ((paeonia lactiflora (pl), atractylodes macrocephala (ama), angelica sinensis (as), astragalus membranaceus (ame), glycyrrhiza uralensis (gu) and rheum officinale (ro)) ... | 2009 | 19483308 |
| determination of the components in a chinese prescription, yu-ping-feng san, by rapd analysis. | in this study, the rapd (random amplified polymorphic dna) technique was employed for the first time to determine the components in a chinese herbal prescription. forty decamer oligonucleotide primers were screened in the rapd analysis to identify three chinese medicines, the dried root of astragalus membranaceus (fisch.) bge., the dried root of ledebouriella seseloides wolff, and the dried rhizome of atractylodes macrocephala koidz, in a chinese prescription. only primer opp-10 simultaneously g ... | 1998 | 9776663 |
| global protein expression analysis of molecular markers of ds-1-47, a component of implantation-promoting traditional chinese medicine. | this study investigated the molecular markers of ds-1-47, a component of an implantation- promoting traditional chinese medicine consisting of astragalus mongholicus, atractylodes macrocephala, scutellaria baicalensis and dipsacales, in an attempt to clarify the molecular mechanism and action targets of ds-1-47. controlled ovarian stimulation (cos) method was used to establish the implantation dysfunction models of mice. animals were divided into normal pregnant group, cos model group and ds-1-4 ... | 2016 | 27924510 |
| the natural compound codonolactone attenuates tgf-β1-mediated epithelial-to-mesenchymal transition and motility of breast cancer cells. | codonolactone (clt), a natural product, is the major bioactive component of atractylodes lancea, and also found in a range of other medical herbs, such as codonopsis pilosula, chloranthus henryi hemsl and atractylodes macrocephala koidz. this sesquiterpene lactone has been demonstrated to exhibit a range of activities, including anti-allergic activity, anti-inflammatory, anticancer, gastroprotective and neuroprotective activity. previously, we found that clt showed significant anti-metastatic pr ... | 2016 | 26549400 |
| anti-tumor effects of atractylenolide-i on human ovarian cancer cells. | background the aim of this study was to investigate the effects of atractylenolide-i (at-i), a naturally occurring sesquiterpene lactone isolated from atractylodes macrocephala koidz, on human ovarian cancer cells. material and methods the viability and anchorage-independent growth of ovarian cancer cells were evaluated using mtt and colony formation assay, respectively. cell cycle and apoptosis were detected with flow cytometry analysis. the level of cyclin b1 and cdk1 was measured using qpcr a ... | 2017 | 28141785 |
| stereoselective total syntheses of polyacetylene plant metabolites via ester-tethered ring closing metathesis. | total syntheses of five naturally occurring polyacetylenes from three different plants are described. these natural products have in common an e,z-configured conjugated diene linked to a di- or triyne chain. as the key method to stereoselectively establish the e,z-diene part, an ester-tethered ring-closing metathesis/base-induced eliminative ring opening sequence was used. the results presented herein do not only showcase the utility of this tethered rcm variant but have also prompted us to sugg ... | 2017 | 28085285 |
| two new compounds from atractylodes macrocephala with neuroprotective activity. | in the present study, two new compounds, together with six known compounds, were isolated from rhizome of atractylodes macrocephala koidz by a series of silica gel, ods column chromatography, and preparative hplc. their structures were characterized as atractylenolide ii (1), atractylenolide i (2), biepiasterolid (3), isoatractylenolide i (4), atractylenolide iii (5), 3β-acetoxyl atractylenolide i (6), (4e,6e,12e)-tetradeca-4,6,12-triene-8,10-diyne-13,14-triol (7), (3s,4e,6e,12e)-1-acetoxy-tetra ... | 2017 | 28027699 |
| the protective effect of atractylenolide i on systemic inflammation in the mouse model of sepsis created by cecal ligation and puncture. | atractylenolide i (at-i), an active compound isolated from atractylodes macrocephala koidz (compositae), shows several pharmacological activities. | 2016 | 25853971 |
| identification of constituent herbs in ginseng decoctions by dna markers. | dna in herbal decoctions is usually fragmented by extensive boiling and is usually regarded as unsuitable for molecular authentication. this study aims to evaluate the feasibility for molecular authentication methods by multiplex polymerase chain reaction (pcr) and dna sequencing for decoctions. | 2015 | 25657815 |
| structure characterization of three polysaccharides and a comparative study of their immunomodulatory activities on chicken macrophage. | in this study, we evaluated structure characterization and immunomodulatory activity of polysaccharides from astragalus aboriginum richardson (raps), atractylodes macrocephala koidz (ramps) and rumia seseloides hoffm (rsps) in vitro on chicken macrophage. we found that molecular weight of raps and ramps was 122.4 and 109.4kda higher than 64.71kda of rsps. glucose occupied 83.95% and 66.39% in raps and ramps, respectively. rsps mainly contained glucose and galacturonic acid, which accounted for 3 ... | 2016 | 27561535 |
| atractylodes lactone compounds inhibit platelet activation. | platelets play a crucial role in the development and progression of atherosclerosis-thrombosis and, therefore, antiplatelet drugs are widely used in the treatment of coronary artery disease. moreover, advances in understanding the biological functions of natural plant products can provide new pharmacological strategies aimed at promoting cardiovascular health. atractylenolide i (atl-1), atl-2, and atl-3 are the major bioactive components of a qi tonifying medicinal herb rhizoma atractylodis macr ... | 2017 | 27560602 |
| danggui-shaoyao-san: new hope for alzheimer's disease. | danggui-shaoyao-san (dss), also called toki-shakuyaku-san (tj-23) or dangguijakyak-san (djs), is a well-known herbal formula (angelica sinensis (oliv.) diels., ligusticum chuanxiong hort., paeonia lactiflora pall., poria cocos (schw.) wolf, alisma orientalis (sam.) juzep., atractylodes macrocephala koidz.), which has been widely used in oriental countries for the treatment of various gynecological diseases. recent studies show that dss has an effect on free radical-mediated neurological diseases ... | 2016 | 27493835 |
| sesquiterpenes from baizhu stimulate glucose uptake by activating ampk and pi3k. | baizhu, the dried rhizome of atractylodes macrocephala koidz (compositae), is one of the most important traditional chinese herbal medicines. baizhu is generally used to treat digestive disorders and diabetes in asian countries. this study investigates the activity of two sesquiterpenes isolated from baizhu, atractylenolide i (at-i) and atractylenolide ii (at-ii), for their effects on glucose uptake in mouse skeletal muscle c2c12 cells, and the corresponding mechanism. these compounds show a sig ... | 2016 | 27430917 |
| polystyrene-divinylbenzene-glycidyl methacrylate stationary phase grafted with poly (amidoamine) dendrimers for ion chromatography. | in this work, a novel ion exchange stationary phase based on different generations of poly (amidoamine) dendrimers (pamam) was developed for the determination of inorganic anions and carbohydrates. synthesis of the pamam was carried out with the polymerization reaction of ethylenediamine and methyl acrylate. the synthesized pamam was then grafted to the polystyrene-divinylbenzene-glycidyl methacrylate (ps-gma) to form pamam-based beads. these beads were finally modified with 1,4-butanediol digly ... | 2016 | 27311659 |
| atractylodes macrocephala koidz stimulates intestinal epithelial cell migration through a polyamine dependent mechanism. | atractylodes macrocephala koidz (amk), a valuable traditional chinese herbal medicine, has been widely used in clinical practice for treating patients with disorders of the digestive system. amk has shown noteworthy promoting effect on improving gastrointestinal function and immunity, which might represent a promising candidate for the treatment of intestinal mucosa injury. the aim of this study was to investigate the efficacy of amk on intestinal mucosal restitution and the underlying mechanism ... | 2015 | 25446597 |
| macrophage activation by polysaccharides from atractylodes macrocephala koidz through the nuclear factor-κb pathway. | atractylodes macrocephala koidz is a traditional herb. atractylodes macrocephalaon polysaccharides (amp) have been found to enhance immunity and improve heart function. however, the mechanisms of the immunomodulatory effect have not been investigated. | 2015 | 25327442 |
| inflammatory inhibitory activity of sesquiterpenoids from atractylodes macrocephala rhizomes. | three new sesquiterpenoids, 13-hydroxyl-atractylenolide ii (1), 4-ketone-atractylenolide iii (2), and eudesm-4(15)-ene-7β,11-diol (3), along with eleven known compounds (4-14), were isolated from the rhizomes of atractylodes macrocephala. the structures and relative configurations of 1-3 were determined by analysis of the spectroscopic data, and the absolute configurations of 1 and 2 were assigned by circular dichroism technique. the anti-inflammatory activities of these isolates were evaluated ... | 2016 | 27150484 |
| a recipe composed of chinese herbal active components regulates hepatic lipid metabolism of nafld in vivo and in vitro. | this study is to investigate the therapeutic effects of the recipe composed of atractylodes macrocephala polysaccharide, chlorogenic acid, and geniposide (named acg) on experimental nonalcoholic fatty liver (nafl). the research was divided into two parts as screening experiment and verification experiment. in the screening experiment, we used high-fat diet (hfd) induced nafl rat model and uniform design to get the recipe from five chinese herbal active components. in the verification experiment, ... | 2016 | 27069915 |
| induction of apoptosis and differentiation by atractylenolide-1 isolated from atractylodes macrocephala in human leukemia cells. | atractylodes macrocephula koidz (a. macrocephula, also known as baizhu) is an important ingredient in several traditional chinese herb complexes for the treatment of abdominal pain and gastroenterology diseases for thousands of years. we previously demonstrated the induction of ros-mediated apoptosis by methanol extract of a. macrocephula in human leukemia cells. after purification and assessment of those active compounds from a. macrocephula ethanol extracts, in this study, we focused on the ma ... | 2016 | 26988300 |
| anti-inflammatory and antinociceptive constituents of atractylodes japonica koidzumi. | the rhizomes of many atractylodes species, including atractylodes chinensis koidzumi, atractylodes macrocephala koidzumi, and atractylodes japonica koidzumi, are collectively termed atractylodis rhizoma. we prepared n-hexane extracts of the three species and evaluated their anti-inflammatory effects on lipopolysaccharide (lps)-induced raw 264.7 cells. among all n-hexane extracts, those of a. japonica most strongly inhibited nitric oxide (no) production in lps-induced raw 264.7 cells; five sesqui ... | 2016 | 26919689 |
| multi-optimization of ultrasonic-assisted enzymatic extraction of atratylodes macrocephala polysaccharides and antioxidants using response surface methodology and desirability function approach. | rhizoma atractylodes macrocephala polysaccharides (ramp) have been reported to have a variety of important biological activities. in this study, an ultrasonic-assisted enzymatic extraction (uaee) was employed to obtain the highest extraction yield and strongest antioxidant activity of ramp and optimized by a multi-response optimization process. a three-level four-factor box-behnken design (bbd) was performed as response surface methodology (rsm) with desirability function (df) to attain the opti ... | 2015 | 26690404 |
| neuroprotection of atractylenolide iii from atractylodis macrocephalae against glutamate-induced neuronal apoptosis via inhibiting caspase signaling pathway. | glutamate-induced excitotoxicity appears to play a crucial role in neurological disorders. neuroprotection against glutamate-induced excitotoxicity has been proposed as a therapeutic strategy for preventing and/or treating these excitotoxicity-mediated diseases. in the present study, atractylenolide iii, which exhibited significantly neuroprotective effect against glutamate-induced neuronal apoptosis, was isolated from atractylodes macrocephala by means of bioactivity-guided fractionation. the i ... | 2014 | 24958167 |
| the roots of atractylodes macrocephala koidzumi enhanced glucose and lipid metabolism in c2c12 myotubes via mitochondrial regulation. | the root of atractylodes macrocephala koidzumi (atractylodis rhizoma alba, ara) is a traditional korean medicine and has been commonly used for weight control. mitochondrial dysfunction appears to be a key contributor to insulin resistance, and therefore mitochondrial targeting drugs represent an important potential strategy for the treatment of insulin resistance and obesity. in this study, the authors investigated the regulatory effects of ara on mitochondrial function with respect to the stim ... | 2015 | 26617661 |
| strong specific inhibition of udp-glucuronosyltransferase 2b7 by atractylenolide i and iii. | drug-metabolizing enzymes inhibition-based drug-drug interaction remains to be the key limiting factor for the research and development of efficient herbal components to become clinical drugs. the present study aims to determine the inhibition of uridine 5'-diphospho-glucuronosyltransferases (ugts) isoforms by two important efficient herbal ingredients isolated from atractylodes macrocephala koidz, atractylenolide i and iii. in vitro recombinant ugts-catalysed glucuronidation of 4-methylumbellif ... | 2016 | 26536846 |
| cryopreservation of in vitro-grown shoot tips of chinese medicinal plant atractylodes macrocephala koidz. using a droplet-vitrification method. | atractylodes macrocephala koidz. is an important medicinal species from china that has been used for thousands of years for its special pharmacological antioxidant, hepatoprotective, anti-inflammatory, anti-allergic, antithrombotic, antiviral, and anticarcinogenic activities. | 2015 | 26510338 |
| the progress of metabolomics study in traditional chinese medicine research. | traditional chinese medicine (tcm) has played important roles in health protection and disease treatment for thousands of years in china and has gained the gradual acceptance of the international community. however, many intricate issues, which cannot be explained by traditional methods, still remain, thus, new ideas and technologies are needed. as an emerging system biology technology, the holistic view adopted by metabolomics is similar to that of tcm, which allows us to investigate tcm with c ... | 2015 | 26477800 |
| what caused the changes in the usage of atractylodis macrocephalae rhizoma from ancient to current times? | ancient chinese medicine treatises on atractylodis macrocephalae rhizoma (amr), the rhizome of atractylodes macrocephala koidz, indicated that it possessed an expectorant effect. however, in modern times, it is commonly used as a tocolytic agent. in this study, the components of amr that are responsible for its expectorant and tocolytic effects were evaluated in order to clarify the differences in its application between ancient and modern times. a decoction of amr was separated into five fracti ... | 2016 | 26382100 |
| complete genome sequence of a tentative new caulimovirus from the medicinal plant atractylodes macrocephala. | a total of nine contigs related to caulimovirus-like sequences were detected using high-throughput paired-end rna sequencing. an attempt to find the plant sample infected with this type of virus identified the medicinal plant atractylodes macrocephala koidzumi showing mild mottle symptoms. subsequently, the complete dna genome sequence of the atractylodes virus was determined. the 8,105-nt genome of the virus was composed of six open reading frames and displayed the highest nucleotide sequence i ... | 2015 | 26350978 |
| anti-tumor effects of atractylenolide i isolated from atractylodes macrocephala in human lung carcinoma cell lines. | atractylenolide i (atl-1) is the major sesquiterpenoid of atractylodes macrocephala. this study was designed to investigate whether atl-1 induced apoptosis in a549 and hcc827 cells in vitro and in vivo. in our results, atl-1 significantly decreased the percentage of in vitro viability, in a dose-dependent manner. in addition, dapi staining and flow cytometry tests demonstrated the induction of apoptosis by atl-i. western blot analysis indicated that the protein levels of caspase-3, caspase-9 and ... | 2013 | 24172243 |
| atractylenolide i protects mice from lipopolysaccharide-induced acute lung injury. | atractylenolide i (ao-i), one of the major bioactive components isolated from rhizoma atractylodes macrocephala, has been reported to have anti-inflammatory effects. in the present study, we investigated the protective effects of ao-i on acute lung injury (ali) using lps-induced ali mouse model. lung injury was assessed by histological study. inflammatory cytokines tnf-α, il-6 and il-1β production were detected by elisa. tlr4 expression and nf-κb activation were measured by western blot analysis ... | 2015 | 26297303 |
| the difference between blood-associated and water-associated herbs of danggui-shaoyao san in theory of tcm, based on serum pharmacochemistry. | danggui-shaoyao san (dss) is a famous chinese formula for activating blood circulation and promoting urination. this study was to investigate the difference of material basis between a blood-associated herbs group and a water-associated herbs group. according to the theory of traditional chinese medicine, the formula can be divided into a blood-associated herbs group (angelica sinensis, paeonia lactiflora and ligusticum chuanxiong) and a water-associated herbs group (atractylodes macrocephala, a ... | 2016 | 26270156 |
| [morphology and aflp analysis of tetraploid plantlets of atractylodes macrocephala]. | in order to investigate the genetic basis of morphological variation of tetraploid plantlets of atractylodes macrocephala, diploid plantlets were taken as experimental material, sterile filtration colchicine was used to soak 0.5-1.0 cm long buds. the difference between morphology and stomatal of diploid and tetraploid of a. macrocephala was compared, and genome polymorphism was explored by aflp. the results showed that the buds dipped in 0.1% colchicine solution for 36 h was optimal conditions t ... | 2015 | 26084160 |
| [authenticate of atractylodes macrocephala seed by amplification refractory mutation system]. | to design specific primers and authenticate atractylodes macrocephala from atractylodes lancea and a. chinensis. | 2013 | 24228563 |
| new bisesquiterpenoid lactone from the wild rhizome of atractylodes macrocephala koidz grown in qimen. | the rhizomes of atractylodes macrocephala are used as both a food source and traditional chinese medicine in china. a phytochemical investigation was carried out on wild a. macrocephala grown in qimen county in eastern china, and yielded a novel bisesquiterpenoid lactone, namely, biatractylenolide ii (1), along with two known compounds, atractylenolide ii (2) and taraxeryl acetate (3). the structure and relative configuration of the new compound were elucidated mainly by 1d and 2d nmr spectrosco ... | 2017 | 28345357 |
| oryeongsan suppressed high glucose-induced mesangial fibrosis. | the pathological change of kidney in diabetic nephropathy is represented hypertrophy, inflammation, and renal fibrosis. oryeongsan, traditional oriental herbal formula, is widely used for the treatment of nephrosis, dropsy, and uremia. this study was examined whether oryeongsan attenuate high-glucose (hg)-promoted rat mesangial cell fibrosis and matrix accumulation, major features of diabetic glomerulosclerosis. | 2015 | 25880429 |
| uplc-q-tof-ms/ms fingerprinting of traditional chinese formula sijunzitang. | sijunzitang (sjzt), a classic traditional chinese formula (tcmf) consisting of four herbs, radix ginseng, atractylodes macrocephala, poria cocos and glycyrrhiza uralensis, has been demonstrated to show protective effects on intestine and stomach injure. the chromatographic quality control is needed. uplc-q-tof-ms is a rapid and efficient technique for analysis of complex sample in combination with uplc and tandem mass spectrometry (ms/ms). in this paper, uplc-ms fingerprinting of sjzt was develo ... | 2013 | 23511229 |
| isolation and characterization of polymorphic microsatellite markers from the chinese medicinal herb atractylodes macrocephala (asteraceae). | atractylodes macrocephala koidz. (asteraceae) is an economically important chinese medicinal herb. in this study, 15 polymorphic microsatellite markers were developed from a. macrocephala using the compound microsatellite marker technique. levels of polymorphism within the 15 markers were assessed using 83 individuals from two wild and two cultivated populations in china. the number of alleles per locus ranged from 2 to 20, with an average of 9.9 alleles. observed and expected heterozygosities r ... | 2012 | 23443109 |
| assessment of the embryotoxicity of four chinese herbal extracts using the embryonic stem cell test. | rhizoma atractylodes macrocephala, radix isatidis, coptis chinensis and flos genkwa are common herbal remedies used by pregnant woman in china. in this study, their potential embryotoxicity was assessed using the embryonic stem cell test (est) and a prediction model. the potential embryotoxicity of the herbs was based on three endpoints: the concentrations of the compounds that inhibited the proliferation of 50% of embryonic stem cells (escs) (ic50es), the concentrations that inhibited 50% of 3t ... | 2015 | 25873199 |
| [genetic diversity of atractylodes macrocephala by issr]. | to assess the genetic diversity of atractylodes macrocephala in 12 cultivated populations and 3 wild populations. | 2012 | 23373206 |
| effect of atractylodes macrocephala on hypertonic stress-induced water channel protein expression in renal collecting duct cells. | edema is a symptom that results from the abnormal accumulation of fluid in the body. the cause of edema is related to the level of aquaporin (aqp)2 protein expression, which regulates the reabsorption of water in the kidney. edema is caused by overexpression of the aqp2 protein when the concentration of na(+) in the blood increases. the rhizome of atractylodes macrocephala has been used in traditional oriental medicine as a diuretic drug; however, the mechanism responsible for the diuretic effec ... | 2012 | 23258995 |
| atractylochromene is a repressor of wnt/β-catenin signaling in colon cancer cells. | wnt/β-catenin signaling pathway was mutated in about 90% of the sporadic and hereditary colorectal cancers. the abnormally activated β-catenin increases the cancer cell proliferation, differentiation and metastasis through increasing the expression of its oncogenic target genes. in this study, we identified an inhibitor of β-catenin dependent wnt pathway from rhizomes of atractylodes macrocephala koidzumi (compositae). the active compound was purified by activity-guided purification and the stru ... | 2015 | 25593640 |
| characterisation of oligosaccharides from baizhu by hilic-ms. | polysaccharides from baizhu were separated by preparative hydrophilic interaction liquid chromatography on an xamide column and its components were characterised as inulin-type polysaccharides with structures of α-d-glucopyranosyl-[-(1 → 2) -β-d-fructofuranosyl-](n -1)-(1 → 2) -β-d-fructofuranoside (n = 3-20) by a combinatory application of electrospray-ionisation mass spectrometry, nuclear magnetic resonance and ir, as well as the chemical analysis of monosaccharide composition. in addition, th ... | 2015 | 25553654 |
| the metabolism of polysaccharide from atractylodes macrocephala koidz and its effect on intestinal microflora. | an active polysaccharide from the rhizome of atractylodes macrocephala koidz (pam) was identified to improve and adjust disordered intestinal flora. high-performance gel permeation chromatography (hpgpc) and gas chromatography-mass spectrometry (gc-ms) were employed to identify the components of pam as rhamnose, glucose, mannose, xylose, and galactose at a ratio of 0.03 : 0.25 : 0.15 : 0.41 : 0.15. pam metabolized in gastrointestinal tract when incubated with artificial gastric and intestinal ju ... | 2014 | 25505927 |
| effect of selenylation modification on immune-enhancing activity of atractylodes macrocephala polysaccharide. | the atractylodes macrocephala polysaccharide (amp) was extracted purified and modified in selenylation by nitric acid-sodium selenite method to get nine selenizing amps (samps), samp(1)-samp(9). in vitro test their effects on chicken peripheral lymphocyte proliferation were determined by mtt assay. the results showed that nine samps and amp at five concentrations could significantly promote lymphocyte proliferation, the actions in six samps were significantly stronger than that in amp, and in sa ... | 2015 | 25453291 |
| dynamic analysis of the endogenous metabolites in depressed patients treated with tcm formula xiaoyaosan using urinary (1)h nmr-based metabolomics. | xiaoyaosan (xys), one of the best-known traditional chinese medicine prescriptions with a long history of use, is composed of bupleurum chinense dc., paeonia lactiflora pall., poria cocos (schw.) wolf, angelica sinensis (oliv.) diels, zingiber officinale rosc., atractylodes macrocephala koidz., glycyrrhiza uralensis fisch., and mentha haplocalyx briq. for centuries, xys has been widely used in china for the treatment of mental disorders such as depression. however, the complicated mechanism unde ... | 2014 | 25448502 |
| [identification of atractylodis macrocephalae rhizoma and atractylodis rhizoma from their adulterants using dna barcoding]. | atractylodis macrocephalae rhizoma and atractylodis rhizoma were widely used in strengthening spleen under different disease conditions, and were easily and often misused each other. therefore, dna barcode was used to distinguish atractylodis macrocephalae rhizoma and atractylodis rhizoma from their adulterants to ensure the safe use. the sequence lengths of its2 of atractylodes macrocephala, atractylodis rhizoma (a. lancea, a. japonica and a. coreana) were both 229 bp. among the its2 sequences ... | 2014 | 25244743 |
| fast analysis of principal volatile compounds in crude and processed atractylodes macrocephala by an automated static headspace gas chromatography-mass spectrometry. | atractylodes macrocephala, a famous herbal medicine, is used extensively in the practice of traditional chinese medicine (tcm). processing procedure is a common approach that usually occurs before a. macrocephala is prescribed. this paper describes a sensitive and specific assay for the determination of principal volatile compounds in crude and processed a. macrocephala. | 2014 | 25210311 |
| codonolactone, a sesquiterpene lactone isolated from chloranthus henryi hemsl, inhibits breast cancer cell invasion, migration and metastasis by downregulating the transcriptional activity of runx2. | metastasis is the most insidious aspect of breast cancer, but effective strategies to control this malignant process are still lacking. in previous studies, we screened over 200 extracts from plants of genus chloranthaceae by bioactivity-guided fractionation, and found that codonolactone (clt) exhibited potential antimetastatic properties in breast cancer cells. this sesquiterpene lactone was isolated from chloranthus henryi hemsl, and is also found in other medical herbs, such as codonopsis pil ... | 2014 | 25190326 |
| [restriction endonuclease digest - melting curve analysis: a new snp genotyping and its application in traditional chinese medicine authentication]. | single nucleotide polymorphisms (snp) is an important molecular marker in traditional chinese medicine research, and it is widely used in tcm authentication. the present study created a new genotyping method by combining restriction endonuclease digesting with melting curve analysis, which is a stable, rapid and easy doing snp genotyping method. the new method analyzed snp genotyping of two chloroplast snp which was located in or out of the endonuclease recognition site, the results showed that ... | 2014 | 24974477 |
| screening for compounds with aromatase inhibiting activities from atractylodes macrocephala koidz. | ten compounds were isolated from the dichloromethane extract of atractylodes macrocephala and their aromatase inhibiting activities were tested using an in vitro fluorescent-based aromatase assay. the results indicated that atractylenolide i, atractylenolide ii and atractylenolide iii had inhibition ratios of 94.56 ± 0.70%, 90.93 ± 1.41% and 86.31 ± 8.46%, respectively, at a concentration of 10 μm. we conclude from our results that atractylenolide and its derivates may serve as potential aromata ... | 2011 | 21494203 |
| chemical and ecological evaluation of a genuine chinese medicine: atractylodes macrocephala koidz. | the study was designated to complete a chemical and ecological evaluation of a genuine chinese medicine atractylodes macrocephala koidz (a. macrocephala) and to explore the existence of correlation between chemical ingredients of different a. macrocephala populations and ecological factors. different samples of a. macrocephala collected from six chinese habitats were analyzed using chemical and ecological methods. the results showed the bioactive ingredients of a. macrocephala to be closely rela ... | 2011 | 22654218 |