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monoclonal antibodies to the molluscan small cardioactive peptide scpb: immunolabeling of neurons in diverse invertebrates.we reported a development of murine monoclonal antibodies to a molluscan small cardioactive peptide (scpb) and their application to immunolabeling of neurons in several molluscan and arthropod species. in vitro stimulations of mouse lymphocytes with scpb conjugated to a carrier protein yielded exclusively igm class antibodies; in vivo stimulation resulted in generation of both igm and igg classes of antibodies. monoclonal antibodies of the igm class labeled identified scp-containing neuron b11 i ...19883062048
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