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neuropeptide y, an orexigenic hormone, regulates phagocytic activity of lizard splenic phagocytes.present in vitro study in the wall lizard hemidactylus flaviviridis, for the first time in ectothermic vertebrates, demonstrated the immunoregulatory role of neuropeptide y (npy) and its receptor-coupled downstream signaling cascade. npy inhibited the percentage phagocytosis and phagocytic index of splenic phagocytes. the inhibitory effect of npy on phagocytosis was completely antagonized by y(2) and y(5) receptor antagonists. this suggests that npy mediated its effect on phagocytosis through y( ...201121527297
role of gonadotropin and leydig cell-secreted factors in the control of testicular macrophage activities in the wall lizard hemidactylus flaviviridis.the present in vitro study for the first time demonstrates the endocrine and paracrine control of testicular macrophage activities in ectodermic vertebrates. follicle-stimulating hormone (fsh) increased phagocytosis and superoxide production by macrophages. in regard to paracrine control, non-activated leydig cell-conditioned medium (lccm) decreased both the activities, whereas fsh-preactivated lccm had differential effects: inhibitory on phagocytosis and stimulatory on superoxide production. ho ...200817825411
immunomodulatory role of substance p in the wall lizard hemidactylus flaviviridis: an in vitro study.present in vitro investigation for the first time in ectotherms demonstrated the immunomodulatory role of substance p in the wall lizard hemidactylus flaviviridis. substance p inhibited the percentage phagocytosis and phagocytic index of lizard splenic phagocytes. inhibitory effect of substance p was completely blocked by nk-1 receptor antagonist spantide i, indicating the nk-1 receptor mediated action. further, nk-1 receptor-coupled downstream signaling cascade involved in controlling phagocyto ...201121788073
dynorphin regulates the phagocytic activity of splenic phagocytes in wall lizards: involvement of a κ-opioid receptor-coupled adenylate-cyclase-camp-pka pathway.this in vitro study of the wall lizard hemidactylus flaviviridis demonstrates the role of the opioid peptide dynorphin a((1-17)) [dyn a((1-17))] in the regulation of the phagocytic activity of splenic phagocytes. dyn a((1-17)) in a concentration-dependent manner inhibited the phagocytic activity, and the maximum inhibition was recorded at a concentration of 10(-9) mol l(-1). to explore the receptor-mediated effect of dyn a((1-17)), cells were treated simultaneously with the non-selective opioid ...201122116765
seasonal changes in plasma steroid levels in relation to ovarian steroidogenic ultrastructural features and progesterone receptors in the house gecko, hemidactylus flaviviridis, in oman.a comprehensive study of the annual ovarian cycle in the house gecko, hemidactylus flaviviridis, was conducted in oman. circulating estradiol (e(2)), progesterone (p), and testosterone (t) were measured during the active and inactive phases of the cycle. the steroid levels were related to the steroidogenic ultrastructural features such as the abundance of smooth endoplasmic reticulum (ser), the presence of cisternal whorls, and close association of lipid droplets with swollen vesiculated mitocho ...201222387987
the reproductive cycle of the male house gecko, hemidactylus flaviviridis, in relation to plasma steroid concentrations, progesterone receptors, and steroidogenic ultrastructural features, in oman.the annual testicular cycle of the house gecko hemidactylus flaviviridis in oman was studied. plasma testosterone (t), estradiol (e2) and progesterone (p) concentrations were measured using a sensitive hplc-ms/ms detection technique. the ultrastructural steroidogenic features in sertoli and leydig cells, which were the major source of steriodogenesis, were examined, using transmission electron microscopy (tem). in addition, progesterone receptors (pr) were examined throughout the testicular cycl ...201323524273
repertoire of bone morphogenetic proteins and growth/differentiation factors in ovary of the indian wall lizard (hemidactylus flaviviridis) with emphasis on differential expression and gonadotropic regulation of bmp15 and gdf9.analysis of ovarian transcriptome of indian wall lizard demonstrates the existence of several bone morphogenetic proteins (bmp1, 2, 3, 3b, 7, 8, 15) and growth/differentiation factors (gdf5, 9) for the first time in reptilian ovary. the characterization of putative full-length/partial protein sequences of bmps (bmp2, 3, 3b, 7, 15) and gdf9 showed high homology of their tgf-β domain with that of other vertebrates while bmp1 bore homology to zinc-dependent metalloprotease. phylogenetic analyses sh ...201728837789
temporal expression and gonadotropic regulation of aromatase and estrogen receptors in the ovary of wall lizard, hemidactylus flaviviridis: correlation with plasma estradiol and ovarian follicular development.the current study in indian wall lizard hemidactylus flaviviridis for the first time demonstrates the reproductive phase-dependent expression pattern of aromatase (cyp19) and estrogen receptor subtypes (er-α and er-β) as well as their gonadotropic regulation in the ovary of a squamate. the expression of cyp19 remained low during regressed phase, increased markedly in recrudescent and declined sharply in breeding phase. further, temporal profile of plasma estradiol 17-β (e2) was found to be relat ...201729042199
protein expression pattern and analysis of differentially expressed peptides during various stages of tail regeneration in hemidactylus flaviviridis.epimorphic regeneration is a process allowing the animal to regain its lost structure which depends on the resident pluripotent stem cells as well as de-differentiation of existing cells to form multi-potent stem cells. many studies have been done to understand the appendage regeneration mechanism. the animal model used since decades is an urodele amphibian the axolotl. however, this ability is also seen in some members of reptiles, mainly lizards which on autotomy of tail regain the same by for ...201829410260
influence of cox-2-induced pge2 on the initiation and progression of tail regeneration in northern house gecko, hemidactylus flaviviridis.we investigated the role of prostaglandin e2 in reptilian regeneration. prostaglandin e2 is known to play a vital role during wound healing and cell proliferation. a significant delay in the rate of growth of regenerate after autotomy was observed when the production of prostaglandin e2 was blocked by usage of specific cyclooxygenase inhibitors as compared to control animals and this delay continued to all the defined stages of regeneration. therefore, prostaglandin e2 could be one of the essent ...200819393133
cyto-architecture and neuronal types of the dorsomedial cerebral cortex of the common indian wall lizard, hemidactylus flaviviridis.the cyto-architecture and morphology of the neuronal types of the dorsomedial cortex of the lizard, hemidactylus flaviviridis has been studied with the help of cresyl violet staining and golgi impregnation method. the dorsomedial cerebral cortex displayed three neuronal layers. layer-i contains only few neuronal somas and also the dendrites ascending from the subjacent layers. layer-ii is characterized by two to three cell thick densely packed neuronal somas. layer-iii contains loosely packed ne ...200919678594
nigella sativa seed extract and its bioactive compound thymoquinone: the new melanogens causing hyperpigmentation in the wall lizard melanophores.the effects of the lyophilized seed extract of nigella sativa and its active ingredient, thymoquinone, were studied on the isolated melanophores of the wall lizard to find the mechanism of skin darkening at the cellular level.201121492177
cox-2 activity and expression pattern during regenerative wound healing of tail in lizard hemidactylus flaviviridis.cyclooxygenase-2 (cox-2) is an important mediator of the immune response. it is found upregulated after pathogen invasion or tissue injury and also in many cancers. of the lesser known functions of this enzyme is its role in effecting epimorphic regeneration. we have previously shown that cox-2 activity is essential for proper regeneration of tail in lizard hemidactylus flaviviridis; however, the pattern of its activity and expression during the early stages of regeneration was unknown. the pres ...201829414669
macroenvironmental influence on hepatozoon lacertilis infectivity to lizard hemidactylus flaviviridis.hemidactylus flaviviridis ruppell, 1835 (n= 199) sampled during different seasons from bareilly (uttar pradesh, india) were infected with a sporozoan parasite belonging to the genus hepatozoon miller, 1908. four morphovariants of the parasite, type i, ii, iii and iv were identified on their growing pattern. when compared with earlier reported species, the parasite could be characterized taxonomically by its comparatively greater length 17.35 (13.57-21.30) microm and width 7.51 (5.59-10.11) micro ...201223033655
role of estrogen in the regulation of spermatogenesis in the indian wall lizard hemidactylus flaviviridis.the role of estrogen in the indian wall lizard, hemidactylus flaviviridis during pmsg induced spermatogenesis in the regression phase and during normal spermatogenesis in the active breeding phase was investigated. blood hormone levels demonstrated a high testosterone to estrogen ratio in the breeding and vice verse during the regressed phase. pmsg treatment (30 iu in 100 µl saline/lizard/alternate day for 30 days) during the regressed phase stimulated spermatogenesis which was associated with a ...201121414318
on the helminth fauna of some iraqi reptiles.a study on the parasitofauna of 7 species of iraqi reptiles revealed the presence of at least 8 adult helminth species and some tentatively identified larvae. the reptiles were hemidactylus flaviviridis, h. persicus, asaccus elisae, spalerosophis d. cliffordi, testudo g. terrestris, mauremys c. caspica and trionyx euphraticus. the helminths found comprised 1 species of digenetic trematodes (telorchis stunkardi), cysticercoids of diplopylidium nolleri and 7 nematode species (thelandros sp., micro ...200718224629
in vitro effect of temperature on phagocytic and cytotoxic activities of splenic phagocytes of the wall lizard, hemidactylus flaviviridis.the in vitro effect of temperature on phagocytosis, nitric oxide production and interleukin-1 (il-1) secretion by splenic phagocytes isolated from the wall lizard (hemidactylus flaviviridis) demonstrated that changes in temperature altered non-specific defenses. the lps-induced percentage phagocytosis and phagocytic index were recorded maximum at 25 degrees c. the phagocytic activity declined considerably when the phagocytes were incubated at low (7 and 15 degrees c) or high (37 degrees c) tempe ...200111423311
effect of gonadotropins and testosterone on the initiation of spermatogenesis in the hypophysectomised indian house lizard, hemidactylus flaviviridis ruppell. 19705423048
paracrine role of testicular macrophages in control of leydig cell activities in the wall lizard, hemidactylus flaviviridis.the present in vitro study in wall lizards hemidactylus flaviviridis demonstrates the differential paracrine role of testicular macrophages in regulation of leydig cell activities under normal physiological and inflammatory condition for the first time in reptiles. to accomplish the objective, the effect of condition media of testicular macrophages incubated in medium alone or with fsh/lps was observed on leydig cell steroidogenesis and proliferation. non-activated testicular macrophage-conditio ...200818086472
differential effects of histamine on leydig cell and testicular macrophage activities in wall lizards: precise role of h1/h2 receptor subtypes.the present study in the wall lizard, hemidactylus flaviviridis, was aimed to understand the role of histamine (ha) in the regulation of leydig cell and testicular macrophage activities, for the first time, in ectothermic vertebrates. although ha did not affect the testosterone production from unstimulated leydig cells, it had dual concentration-related effects, stimulatory at a low concentration of 10(-10) m while inhibitory at a high concentration of 10(-5) m, on fsh-induced testosterone produ ...200717641291
cellular mechanism of estrogen-induced thymic involution in wall lizard: caspase-dependent action.the present study, for the first time in an ectothermic vertebrate, demonstrates the cellular mechanism of estrogen-induced thymic involution. ovariectomy in lizards during the preparatory phase of the reproductive cycle resulted in distinct differentiation of cortico-medullary regions and increase in cellularity, especially in the cortical region. the ovariectomy-induced changes were reversed following administration of 17-estradiol (e2), suggesting a primary role of e2 in causing thymic atroph ...200616526045
mechanism of androgen-induced thymic atrophy in the wall lizard, hemidactylus flaviviridis: an in vitro study.the present in vitro study demonstrates the effect of androgen on thymocyte apoptosis leading to thymic atrophy in the wall lizard, hemidactylus flaviviridis. thymocytes collected from castrated lizards were incubated with varying concentrations of dihydrotestosterone (dht) to observe its effect on proliferation and apoptosis. dht treatment reduced the tritiated thymidine incorporation in thymocytes, suggesting that androgen directly inhibits thymocyte proliferation. it also caused apoptosis of ...200516004999
endocrine and paracrine control of leydig cell steroidogenesis and proliferation in the wall lizard: an in vitro study.the present in vitro study, for the first time, demonstrates the endocrine as well as paracrine control of leydig cell steroidogenesis and proliferation in the wall lizard hemidactylus flaviviridis. unlike mammals, leydig cell activity in the wall lizard seems to be directly controlled by ovine follicle-stimulating hormone (fsh)-like molecule, since fsh increased the testosterone production and tritiated thymidine ([(3)h]tdr) incorporation by leydig cells. in addition, sertoli cell paracrine fac ...200515613273
significance of regional difference in ion concentrations in lizard, hemidactylus flaviviridis (rüppell): assessment of ionic influence on sperm motility in vitro.a gradual increase in the concentration of ca2+ from anterior to the posterior region was observed when mono- and divalent cations were estimated in different segments of the epididymis in wall lizard. na+ and k+ levels increased from anterior to middle segment but declined significantly in the posterior segment. however, no significant difference in the levels of mg2+ was observed in various segments. to study the influence of mono- and divalent cations on sperm motility in vitro, the spermatoz ...200315320497
on the life cycle and morphology of development stages of paraspiralatus sakeri gibbons et al., 2004 (nematoda: spiroidea, spirocercidae), a heteroxenic stomach parasite of falcons.pitted darkling beetles (adesmia cancellata) were infected with nematode eggs found in the alimentary tract of a gyrfalcon (falco rusticolus) naturally infected with paraspiralatus sakeri. third-stage larvae in numbers between 1 and 84 were removed from the beetles 5 weeks postinfection and were used for morphological studies as well as to infect domestic chicken, yellow-bellied geckos (hemidactylus flaviviridis) and fringe-toed lizards (acanthodactylus schmidti). all experimental animals, necro ...201424652447
gross morphology of ovarian changes during the reproductive cycle of indian lizards (calotes versicolor and hemidactylus flaviviridis).a comparative study has been made of the reproductive cycle and gross ovarian changes in two species of indian lizards (calotes versicolor and hemidactylus flaviviridis), which are oviparous. they exhibit a single, short breeding season that extends over a few months. calotes ovalutes 10 to 32 eggs per clutch (the highest number recorded so far for lizards belonging to the family agamidae) from last week of june to the first week of september, with july through august being the months of highest ...20051239909
transcriptome analysis of spermatogenically regressed, recrudescent and active phase testis of seasonally breeding wall lizards hemidactylus flaviviridis.reptiles are phylogenically important group of organisms as mammals have evolved from them. wall lizard testis exhibits clearly distinct morphology during various phases of a reproductive cycle making them an interesting model to study regulation of spermatogenesis. studies on reptile spermatogenesis are negligible hence this study will prove to be an important resource.201323536792
seasonal dynamics of thelandros maplestonei infections in the wall lizard, hemidactylus flaviviridis in imphal valley, manipur, india.the influence of seasons on the population dynamics of the nematode, thelandros maplestonei infection in hemidactylus flaviviridis was studied for one annual cycle in the imphal valley, manipur, india. various factors like the incidence, intensity, density, index of infection and dominance of this parasite was observed in relation to temperature and rainfall. the incidence, intensity, density, index of infection and dominance of t. maplestonei was higher in monsoon season, while lowest during wi ...201324431569
a study of differential expression of testicular genes in various reproductive phases of hemidactylus flaviviridis (wall lizard) to derive their association with onset of spermatogenesis and its relevance to mammals.testis of hemidactylus flaviviridis, commonly known as indian wall lizard, displays a lack of cellular and metabolic activity in regressed phase of testis during non-breeding season of the year. retracted sertoli cells (sc), fibroid myoid cells and pre-meiotic resting spermatogonia are observed in such testis. this situation is akin to certain forms of infertility in men where hormone supplementation fails to generate sperm despite the presence of sc and germ cells (gc) in testis. in testis of l ...201626963275
alterations in liver dehydrogenases during tail regeneration in the gekkonid lizard, hemidactylus flaviviridis.histochemical studies on the activities of alpha-gpdh, ldh, sdh and mdh in liver have been carried out during the different phases of tail regeneration in the lizard, hemidactylus flaviviridis. changes in the metabolic activities of the liver during regeneration indicate that during the initial phases of regeneration (namely, wound healing and blastema formation) the energetics of the hepatic tissue are anaerobically oriented, but later (i.e. during the growth phase) the tca cycle appears to be ...1979500487
histochemical observation of the cortical zone of oocyte of indian wall lizard, hemidactylus flaviviridis (rüppel).the cortical zone of oocytes, which lies just below the follicular epithelium appears in the early stages of development, but reaches its fullest growth in vitellogenic oocytes. in the present studies it was found that the cortical zone of hemidactylus flaviviridis consists of proteins, lipoproteins, carbohydrates, fatty yolk, rna and little amount of dna in mature oocytes along with mitochondria and golgi bodies. in the early oocyte, this zone is fine granular in nature, but during the yolky st ...1979488864
histochemistry of ovarian changes in the house lizard, hemidactylus flaviviridis. 1978717067
tracing the evolutionary lineage of pattern recognition receptor homologues in vertebrates: an insight into reptilian immunity via de novo sequencing of the wall lizard splenic transcriptome.reptiles remain a deprived class in the area of genomic and molecular resources for the vertebrate classes. the transition of squamates from aquatic to terrestrial mode of life caused profound changes in their immune system to combat the altered variety of pathogens on land. the current study aims at delineating the evolution of defence mechanisms in wall lizard, hemidactylus flaviviridis, by exploring its immunome. de novo sequencing of splenic transcriptome from wall lizard on the illumina hi- ...201627032500
interrelationship among testicular cells in wall lizard hemidactylus flaviviridis (rüppell): an ultrastructural seasonal and experimental study.the present study was aimed at investigating ultrastructure of different testicular cells and their interactions through various junctional specializations during different phases of reproductive cycle in wall lizard h. flaviviridis to develop an integrated approach of cell-cell interaction in control of testicular functions. specialized steroid synthesizing cell organelles such as smooth endoplasmic reticulum (ser) and long slender mitochondria with tubulo-vesicular cristae were predominantly s ...200415088688
in vitro effect of fsh and testosterone on sertoli cell nursing function in wall lizard hemidactylus flaviviridis (rüppell).the present in vitro sertoli cell-enriched culture study was aimed to understand the precise role of fsh and testosterone either alone or in combination in regulation of sertoli cell nursing function such as lactate production, which in turn is utilized by the germ cells as an energy substrate. the stimulatory effect of fsh on lactate production by sertoli cell-enriched culture was significantly enhanced when fsh and dihydrotestosterone were supplemented in the medium either simultaneously or dh ...200415028526
thyroid activity and (hemidactylus flaviviridis rüppell) in relation to sex hormones. 19744422812
effect of chlorpromazine and morphine on the neurosecretory system of the indian wall lizard hemidactylus flaviviridis (ruppell). 19744450630
hypothalamo-hypophysial neurosecretory and portal system of the indian wall lizard, hemidactylus flaviviridis. 19744136789
seasonal variations in the pattern of lipids in the sexual segment, kidney and liver of the indian house lizard, hemidactylus flaviviridis ruppell. 19724401146
ascorbic acid in the normal and regenerating tail of the house lizard, hemidactylus flaviviridis. 19714258065
seasonal changes in the testicular lipids and after hypophysectomy in the indian house lizard, hemidactylus flaviviridis ruppell. 19715102495
hormonal control of the maintenance of spermatogenesis and sexual segment in the indian house lizard hemidactylus flaviviridis ruppell. 19705435509
effect of sex hormones on the sexual segment of kidney and other accessory reproductive organs of the indian house lizard hemidactylus flaviviridis ruppell. 19695765435
phospholipids in the androgen stimulated sexual segment of the kidney of the indian house lizard, hemidactylus flaviviridis rüppell. 19665960071
sexual segment of the kidney of the indian house lizard, hemidactylus flaviviridis rüppell. 19665956245
dual mode of catecholamine action on splenic macrophage phagocytosis in wall lizard, hemidactylus flaviviridis.in the present study, in vitro concentration-related effect of catecholamines, dopamine (da), norepinephrine (ne), and epinephrine (e) was observed on phagocytic activity of splenic macrophages to understand the impact of sympatho-adrenal-medullary (sam) activation on innate immunity in wall lizard hemidactylus flaviviridis under stress condition. restraint stress for 1 h resulted in marked suppression of macrophage phagocytosis, suggesting that supra-physiological level of catecholamines in res ...200415028521
ecological attributes of hepatozoon lacertilis gupta et al., 2011 susceptibility in indian lizards, hemidactylus flaviviridis (gekkonidae) and calotes versicolor (agamidae).ecological attributes of haematozoan parasites are poorly understood. in this study, we report haematozoan prevalence in two species of indian lizards, hemidactylus flaviviridis (family: gekkonidae) and calotes versicolor (family: agamidae) under three macro-environmental variables: host location, weight and seasonal variations. hemidactylus flaviviridis (n= 199) and calotes versicolor (n= 34) were sampled from bareilly, chandausi and mirzapur, uttar pradesh, india belonging to different weight ...201323665714
on the structure and development of the vertebral column in the house-gecko, hemidactylus flaviviridis ruppel. 195813559740
glucocorticoid-induced thymocyte apoptosis in wall lizard hemidactylus flaviviridis.the aim of the present study is to demonstrate the phenomenon and mechanism of gc-induced cell death of thymocytes in wall lizard hemidactylus flaviviridis. lizard thymocytes were treated in vitro with different concentration of corticosterone (cs) for varying durations and the genomic dna was analyzed both by agarose gel electrophoresis and flow cytometry. corticosterone induced dna fragmentation in a dose-dependent manner, as the dna laddering was more prominent at 10(-14) m than at lower conc ...200414723881
steroid synthesizing cellular sites in the ovaries of calotes versicolor (daud.), hemidactylus flaviviridis (ruppel) & chamaeleon calcaratus (boulenger): histochemical study.a histochemical study of steroid synthesizing cellular sites in the ovaries of calotes versicolor (daud.), hemidactylus flavivirdes (ruppel) and chamaeleon calcaratus (boulenger) is discussed. the distribution of delta 5-3beta-hydroxysteroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase, 11beta-hydroxysteroid dehydrogenase, glucose-6phosphate dehydrogenase, isocitrate dehydrogenase, lactate dehydrogenase and reduced nicotinamide-adenine dinucleotide diaphorase enzyme activities was studied ...19761024992
effects of cyproterone acetate and flutamide on the testis and epididymis of the indian wall lizard, hemidactylus flaviviridis (ruppell).intramuscular injections of 0.2 mg cyproterone acetate (ca) or flutamide every other day for 6 weeks resulted in the inhibition of spermatogenesis. while ca treatment reduced the weight of the testis significantly, flutamide did not. inhibition of steroidogenesis, indicated by an accumulation of sudanophilic lipid and a decrease in delta 5-3 beta-hydroxysteroid dehydrogenase and glucose-6-phosphate dehydrogenase activity, was evident in the leydig cells of ca-treated testis. flutamide, on the ot ...19862948871
dose and time-related in vitro effects of glucocorticoid on phagocytosis and nitrite release by splenic macrophages of wall lizard hemidactylus flaviviridis.glucocorticoids (gc) are usually considered to be immunosuppressive and anti-inflammatory. however, recent studies in mammals have demonstrated the diverse effects of gc on non-specific host-defense mechanism, depending on dose or duration of treatment. hence, in the present study in vitro dose and time-related effects of glucocorticoid, i.e. hydrocortisone (hc) on phagocytosis and nitrite production by lps-induced splenic macrophages in wall lizard hemidactylus flaviviridis has been investigate ...200212223202
thymic structural changes in relation to seasonal cycle and testosterone administration in wall lizard hemidactylus flaviviridis (ruppell).light microscopic and ultrastructural studies of thymus in wall lizard showed remarkable season dependent structural changes. in winter, the thymus was involuted and its cortico-medullary differentiation was not distinct. thymocytes were sparsely distributed. the epithelial cells exhibited atrophic features such as an appreciable decrease in the nuclear-cytoplasmic ratio and accordingly reduction in cell organelles. the reconstruction of thymus commenced during spring and it became fully develop ...200112019754
in vitro effect of sex steroids on cytotoxic activity of splenic macrophages in wall lizard (hemidactylus flaviviridis).sexual dimorphism was observed in nitrite release and il-1-like molecule production by splenic macrophages of the wall lizard (hemidactylus flaviviridis), with a higher level in females than in males. gonadectomy in both males and females resulted in a considerable increase of nitrite and il-1-like molecule secretion, suggesting that the sex hormones inhibit cytotoxic activity of macrophages. to verify this assumption, dose- and time-related in vitro experiments with male and female sex steroids ...200211884072
histological and structural observations on pre-anal glands of the gekkonid lizard, hemidactylus flaviviridis.this paper describes a structural and histological study of the pre-anal glands of hemidactylus flaviviridis. only males possess these glands, which have a tubulo-acinar structure. they are holocrine in nature and become hyperactive during the breeding period. thus they may be involved in the production of pheromones for socio-sexual communication.19863693051
epididymal protein secretion and its androgenic control in wall lizards hemidactylus flaviviridis (ruppell).the total protein level in different segments of epididymis of normal lizard exhibited noticeable increase from early february to late march of a same reproductive phase. comparison among the protein level of different epididymal segments showed insignificant variation from anterior to posterior part in early february but in late march, the protein level in posterior segment was appreciably higher than in anterior and middle segments. further, testosterone-induced epididymal protein did not exhi ...200011215317
is the pineal involved in the stimulatory influence of prolactin on tail regeneration in lizards? studies with exogenous prolactin in lizards exposed to continuous darkness.we have recently demonstrated that continuous light stimulates tail regeneration in the gekkonid lizard, hemidactylus flaviviridis, whereas continuous darkness and pinealectomy depress regeneration. as a sequel to this observation, the effect of exogenous ovine prolactin (oprl) on tail regeneration in normal (nl) and pinealectomized (px) hemidactylus exposed to continuous darkness (l:d 0:24) during the monsoon season was investigated. once-daily intraperitoneal (ip) injections of 500 micrograms/ ...19892591714
parachlorophenylalanine retards tail regeneration in the gekkonid lizard hemidactylus flaviviridis exposed to continuous light.parachlorophenylalanine (p-cpa) was used for chemical pinealectomy in a study of tail regeneration in the gekkonid lizard, hemidactylus flaviviridis. two doses of p-cpa (200 or 400 micrograms kg-1 body mass) were injected into two groups of lizards (5 days prior to and 30 days after caudal autotomy) exposed to continuous light of 2500 lx intensity during the summer season (march-may). our observations show that the initiation of regeneration, the daily growth rate, the total length of new growth ...19892525170
preliminary evidence for pineal-mediated extraretinal photoreception in relation to tail regeneration in the gekkonid lizard, hemidactylus flaviviridis.the tail of the gekkonid lizard hemidactylus flaviviridis was autotomized and the animals were subjected to eight different photoperiodic schedules during the process of tail regeneration. our previous observation had shown that long-day photoperiods stimulate the regeneration process, whereas short-day photoperiods depress it. furthermore, it has also been demonstrated that the lateral eyes, or retinae, do not participate in photoperiodically significant photoreception in h. flaviviridis, as bl ...19892915322
gonadectomy and tail regeneration in the gekkonid lizard hemidactylus flaviviridis. 19883248840
local and systemic alterations in cholinesterase activity during tail regeneration in normal and adrenal suppressed gekkonid lizards hemidactylus flaviviridis. 19883248827
effects of season, ovariectomy and mammalian gonadotropins on the oviduct of indian wall lizard hemidactylus flaviviridis (ruppel).the oviducts of hemidactylus flaviviridis exhibited seasonal changes and their enlargement coincided with a gradual increase in the size of the ovaries. during the breeding season (april) the oviductal wall was lined by tall, columnar epithelium which consisted of flask-like ciliated and nonciliated cells. the epithelium reacted strongly with pas and sudan black-b and exhibited delta 5-3 beta-hydroxysteroid dehydrogenase (delta 5-3 beta-hsd) and glucose-6-phosphate dehydrogenase (g-6-pd) activit ...19853939561
free amino acids during tail regeneration in the gekkonid lizard hemidactylus flaviviridis. 1979544477
thyroid-gonad interrelationship & its effect on growth rate of regenerating tail in the gekkonid lizard hemidactylus flaviviridis. 1979544466
morphology of ovarian changes during the reproductive cycle of the house lizard, hemidactylus flaviviridis.ovarian changes during the reproductive cycle of the oviparous wall lizard (hemidactylus flaviviridis rüppel) are described and discussed. it ovulates from mid-march to mid-may with a peak in april. two eggs, one from each ovary, are ovulated at a time. after the breeding season is over, the ovaries are reduced in size. from june to third week of february they contain small pre-vitellogenic fillicles which start increasing in size with the approach of march when yolk deposition occurs rapidly. t ...19761015364
histochemical analysis of mucosubstances in thyroid c cells of wall lizard hemidactylus flaviviridis. 1976992742
possible role of beta-glucuronidase in the normal and regenerating tail of the house lizard, hemidactylus flaviviridis.histochemical demonstration of beta-glucuronidase was carried out in the normal and regenerating tail of the house lizard, hemidactylus flaviviridis. greater enzyme activity was particularly discernible in the stratum germinativum of the skin of the normal and fully regenerated tail. during regeneration most of the cellular elements of the blastema and the differentiating regenerate exhibited enzyme activity. distribution of the enzyme beta-glucuronidase is correlated with the high degree of cel ...1976970088
seasonal variation in testis and total body cholesterol in the indian house lizard, hemidactylus flaviviridis rüppell. 19655882523
phospholipids of the sexual segment of the kidney of the indian house lizard, hemidactylus flaviviridis ruppell. 196514283078
fibroblast growth factor-2 signaling modulates matrix reorganization and cell cycle turnover rate in the regenerating tail of hemidactylus flaviviridis.lizards restore their lost tail by the recruitment of multipotent cells which are selectively differentiated into varied cell types so as to sculpt a new tail. the precise coordination of the events involved in this complex process requires crosstalk between many signaling molecules and differential regulation of several mediators that facilitate the achievements of various milestones of regeneration. fibroblast growth factor-2 is one such signaling molecule which activates a number of intracell ...202031780191
cyclooxygenase-2 interacts with mmp and fgf pathways to promote epimorphic regeneration in lizard hemidactylus flaviviridis.cyclooxygenase-2 (cox-2) is an inducible enzyme known for its role in promoting inflammation, pain and cancer. it has more recently been attributed a function in epimorphic regeneration of vertebrate appendages. however, its position among the molecular regulators of regeneration remains unclear. this work was aimed at analyzing the influence of cox-2 on critical mediators of regenerative processes in the lizard hemidactylus flaviviridis. it was found during the early events of regeneration that ...201830196771
inhibition of cyclooxygenase-2 alters wnt/β-catenin signaling in the regenerating tail of lizard hemidactylus flaviviridis.epimorphic regeneration in vertebrates involves the restoration of lost tissue or organs through the formation of a regeneration blastema and occurs through a complex interaction of a number of molecular signaling pathways. of the many effectors of successful tail regeneration in the lizard hemidactylus flaviviridis, one crucial pathway is the cyclooxygenase-2 (cox-2) mediated pge2 signaling pathway. the current study was aimed at understanding whether cox-2 signaling plays any role in the expre ...201730603474
epididymis of the indian wall lizard (hemidactylus flaviviridis) during the sexual cycle and in response to mammalian pituitary gonadotropins and testosterone. 198729907006
epididymal influence on acquisition of sperm motility in the gekkonid lizard hemidactylus flaviviridis.total sperm count and percent sperm motility were noted in different parts of the epididymis, and the effect of anterior, middle, and posterior epididymal fluid on the induction of motility of nonmotile testicular spermatozoa was observed. the results were used to compare the influence of different parts of epididymis of hemidactylus flaviviridis on the acquisition of sperm motility, which is a sign of sperm maturation. spermatozoa collected from different regions of the ductus epididymidis show ...20069272226
effects of cyproterone acetate on fsh and testosterone influenced spermatogenesis, steroidogenesis and epididymis in the indian wall lizard, hemidactylus flaviviridis (ruppell).the effects of fsh, testosterone and either cyproterone acetate (cpa) alone or in combination with fsh or testosterone on testis and epididymis in male lizards were studied histologically and histochemically during recrudescent phase to find out whether the onset of spermatogenesis is androgen dependent or fsh dependent. the testes of control lizards consisted of mainly spermatogonia, a few primary spermatocytes and secondary spermatocytes rarely. the interstitial or leydig cells were atrophied. ...19958907557
testis and epididymis of the indian wall lizard (hemidactylus flaviviridis): effects of flutamide on fsh and testosterone influenced spermatogenesis, leydig cell, and epididymis.to determine the separate spermatogenic actions of fsh and testosterone, adult male lizards hemidactylus flaviviridis with recrudescent testes were administered the non-steroidal antiandrogen flutamide either alone or in combination with fsh or testosterone, and the histology and histochemistry of the testes and ductus epididymides were studied. flutamide-treated animals displayed a marked hypertrophy of leydig cells. a few spermatids were also seen in testis of more than half the animals treate ...19911960735
dopamine antagonist speeds up tail regeneration in lizards exposed to continuous darkness: evidence for prolactin involvement.in earlier studies, we demonstrated that continuous light (ll:ld, 24:0) stimulated tail regeneration whereas continuous darkness (dd:ld, 0:24) and pinealectomy depressed the same in the gekkonid lizard, hemidactylus flaviviridis, and, furthermore, exogenous prolactin significantly enhanced the regeneration process in lizards kept in 0:24 ld. however, the regeneration process in animals exposed to 24:0 ld was unaffected by the dopamine agonist, bromocriptine. this study with pimozide, an antipsyc ...19892813444
inherent variations in the cellular events at the site of amputation orchestrate scar-free wound healing in the tail and scarred wound healing in the limb of lizard hemidactylus flaviviridis.lizards are unique in having both-regeneration competent (tail) as well as non-regenerating appendages (limbs) in adults. they therefore present an appropriate model for comparing processes underlying regenerative repair and nonregenerative healing after amputation. in the current study, we use northern house gecko hemidactylus flaviviridis to compare major cellular and molecular events following amputation of the limb and of the tail. although the early response to injury in both cases comprise ...201830054965
proceedings: histochemical demonstration of steroidogenic activity in the ovaries of two lizards, calotes versicolor and hemidactylus flaviviridis. 20154842313
on a new reptilian cestode oochoristica pauriensis n.sp. from hemidactylus brooki (gray) and hemidactylus flaviviridis (ruppell) from garhwal hills, u.p., india.oochoristica pauriensis n.sp. has been described and figured from hemidactylus brooki(gray) and h. flaviviridis(ruppell) on size of strobila, scolex, suckers, testes, ovary, eggs and oncosphere, and number of testes. the new species has been compared with close species.198412891038
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