| chemical constituents of the seeds and bark of syzygium cumini. | | 1975 | 1208683 |
| hypoglycemic activity of eugenia jambolana and ficus bengalensis: mechanism of action. | the extract of jaman pulp from fruit of eugenia jambolana showed hypoplycemic activity. this report is the first evidence of such activity in relation to pulp. the effect of pulp was seen in 30 min, while the seeds of the same fruit required 24 hr. the extracts of bark of ficus bengalensis caused reduction in blood sugar level. these results were confirmed in streptozotocin-induced diabetic animals. the oral administration of the extract resulted in enhancement in serum insulin levels in normogl ... | 1991 | 1768783 |
| antifertility effect in male rats of oleanolic acid, a triterpene from eugenia jambolana flowers. | the antifertility activity of oleanolic acid (c30h48o3), isolated from the flowers of eugenia jambolana, was evaluated in male albino rats. the administration of the compound for 60 days decreased the fertilizing capacity of the animals without any significant changes in body weight or reproductive organ weights. the compound produced arrest of spermatogenesis but did not cause any abnormality to spermatogenic cells, leydig interstitial cells and sertoli cells. oleanolic acid may prove to be a p ... | 1988 | 3199836 |
| [regression of cataract and hyperglycemia in diabetic sand rats (psammomys obesus) having received an extract of eugenia jambolana (lamarck)]. | | 1972 | 4622072 |
| [comparative study of the effect of a principle extracted from eugenia jambolana bark with nn-methyldimethyl biguanide and glybutamide on induced hypoglycemia in normal rats]. | | 1972 | 4628567 |
| [anorexigenic power of a principle extracted from the rotra of madagascar (eugenia jambolana lamarck)]. | | 1967 | 4962179 |
| [contribution to the study of the action of a principle extracted from the myrtle of madagascar (eugenia jambolana, myrtaceae) on blood sugar of the normal rat]. | | 1967 | 4963482 |
| [study of the metabolic modifications induced by extracts of eugenia jambolana (myrtacea lamarck) from madagascar on the rat and the mouse]. | | 1968 | 4970672 |
| tannins in black-plum (syzygium cumini l.) seeds. | | 1972 | 5085637 |
| effects of oral administration of eugenia jambolana seeds & chloropropamide on blood glucose level & pancreatic cathepsin b in rat. | | 1981 | 7341418 |
| the effect of syzygium cumini (l.) skeels on post-prandial blood glucose levels in non-diabetic rats and rats with streptozotocin-induced diabetes mellitus. | this study was undertaken to investigate whether a tea prepared from syzygium cumini, reported to be used by diabetics in porto alegre, brazil, might have an antihyperglycemic effect in experimental models. teas prepared from leaves and seeds of s. cumini, in concentrations ranging from 2-64 g/l, were administered, as water substitute for 14-95 days, to 16 groups with 8-9 normal albino rats and to four groups with 10-12 rats with streptozotocin-induced diabetes mellitus. post-prandial blood gluc ... | 1997 | 9201610 |
| screening of anti-diarrhoeal profile of some plant extracts of a specific region of west bengal, india. | ethanol extract of four different plants of the khatra region of the bankura district of west bengal, india were evaluated for anti-diarrhoeal activity against different experimental models of diarrhoea in rats. the extracts of ficus bengalensis linn. (hanging roots), eugenia jambolana lam. (bark), ficus racemosa linn. (bark) and leucas lavandulaefolia rees (aerial parts) showed significant inhibitory activity against castor oil induced diarrhoea and pge2 induced enteropooling in rats. these ext ... | 1998 | 9533436 |
| absence of antihyperglycemic effect of jambolan in experimental and clinical models. | the use of alternative therapies to treat diabetes, including teas prepared with different vegetables, is widespread in brazil. in porto alegre, a southern city of brazil, the tea prepared from leaves of syzygium cumini (l.) skeels or s. jambos (l.) alst has been report to be used frequently by diabetic patients. we investigated the postulated antihyperglycemic effect of the s. cumini (l.) skeels in three experiments. in the first, a randomized, parallel, placebo controlled trial, tea prepared f ... | 2000 | 10904184 |
| anti-hyperglycemic effect of eugenia jambolana and tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. | in india, the decoction of kernels of eugenia jambolana (ej) and extracts of tinospora cordifolia (tc) are used as a household remedy for diabetes. these also form constituents of many herbal formulations for diabetes that are marketed in this country. the anti-hyperglycemic effect of aqueous and alcoholic extracts as well as lyophilized powder of these two plants was evaluated in diabetic animals using different doses of diabetogenic agents for varying duration (21-120 days) so as to assess the ... | 2000 | 11091000 |
| lack of antidiabetic effect of a eugenia jambolana leaf decoction on rat streptozotocin diabetes. | streptozotocin-diabetic rats were treated for 17 days with a decoction of eugenia jambolana (myrtaceae) leaves (15%, w/v) as a substitute for water. body weight, food and fluid intake, urine volume, glycemia, urinary glucose and urea were evaluated every 5 days. the animals were sacrificed by decapitation and blood samples collected for the determination of glycemia, serum cholesterol, hdl-cholesterol, triglycerides and angiotensin-converting enzyme. the weight of adipose and muscle tissues was ... | 2001 | 11262591 |
| treatment with extracts of momordica charantia and eugenia jambolana prevents hyperglycemia and hyperinsulinemia in fructose fed rats. | insulin resistance has been implicated as a major contributor to the development of hyperglycemia in niidm patients. herbal extracts of momordica charantia (mc) and eugenia jambolana (ej) have been shown to reduce hyperglycemia in diabetic animal models and human patients. however, no work has been done so far to assess their effect on insulin resistance. this study was undertaken to study the effects of different doses (100,200 and 400 mg per day) of alcoholic and aqueous extracts of mc and ej ... | 2001 | 11390126 |
| anti-inflammatory activity of syzygium cumini bark. | the ethanolic extract of the bark of syzygium cumini was investigated for its anti-inflammatory activity in animal models. the extract did not show any sign of toxicity up to a dose of 10.125 g/kg, p.o. in mice. significant anti-inflammatory activity was observed in carrageenin (acute), kaolin-carrageenin (subacute), formaldehyde (subacute)-induced paw oedema and cotton pellet granuloma (chronic) tests in rats. the extract did not induce any gastric lesion in both acute and chronic ulcerogenic t ... | 2001 | 11395258 |
| traditional indian anti-diabetic plants attenuate progression of renal damage in streptozotocin induced diabetic mice. | the purpose of the study was to investigate the effects of daily oral feeding momordica charantia (mc) (200 mg/kg), eugenia jambolana (ej) (200 mg/kg), mucuna pruriens (mp) (200 mg/kg) and tinospora cordifolia (tc) extracts for 40 days on blood glucose concentrations and kidney functions in streptozotocin (stz)-diabetic rats. plasma glucose levels, body weight, urine volume and urinary albumin levels were monitored on every 10th day over a 40-day period while plasma creatinine levels were assess ... | 2001 | 11448544 |
| medicinal plants of india with anti-diabetic potential. | since ancient times, plants have been an exemplary source of medicine. ayurveda and other indian literature mention the use of plants in treatment of various human ailments. india has about 45000 plant species and among them, several thousands have been claimed to possess medicinal properties. research conducted in last few decades on plants mentioned in ancient literature or used traditionally for diabetes have shown anti-diabetic property. the present paper reviews 45 such plants and their pro ... | 2002 | 12020931 |
| syzygium cumini (jamun) reduces the radiation-induced dna damage in the cultured human peripheral blood lymphocytes: a preliminary study. | the effects of various concentrations (0.0, 1.56, 3.125, 6.25, 12.5, 25, 50 and 100 microg/ml) of the leaf extract of syzygium cumini linn. or eugenia cumini (sc; black plum, jamun, family myrtaceae) was studied on the alteration in the radiation-induced micronuclei formation in the cultured human peripheral blood lymphocytes. treatment of lymphocytes to various concentrations of sc resulted in a dose dependent increase in the micronuclei-induction, especially after 25-100 microg/ml extract. the ... | 2002 | 12084616 |
| antibacterial activity of syzygium cumini and syzygium travancoricum leaf essential oils. | the leaf essential oils of syzygium cumini and syzygium travancoricum were tested for their antibacterial property. the activity of s. cumini essential oil was found to be good, while that of s. travancoricum was moderate. | 2002 | 12165339 |
| prevention of experimental diabetic cataract by indian ayurvedic plant extracts. | the efficacy of momordica charantia (mc), eugenia jambolana (ej), tinospora cordifolia (tc) and mucuna pruriens (mp) was assessed in the prevention of murine alloxan dibetic cataract. alloxan (120 mg/kg) was used as the diabetogenic agent. while controls and diabetic controls did not receive any plant extract, treated rats received lyophilized aqueous extract of mc and ej (200 mg/kg p.o.), alcohol extract of tc (400 mg/kg) and mp (200 mg/kg p.o.) every day until 4 months. serum glucose concentra ... | 2002 | 12458487 |
| comparative evaluation of hypoglycaemic activity of some indian medicinal plants in alloxan diabetic rats. | in our experiments 30 hypoglycaemic medicinal plants (known and less known) have been selected for thorough studies from indigenous folk medicines, ayurvedic, unani and siddha systems of medicines. in all the experiments with different herbal samples (vacuum dried 95% ethanolic extracts), definite blood glucose lowering effect within 2 weeks have been confirmed in alloxan diabetic albino rats. blood glucose values are brought down close to normal fasting level using herbal samples at a dose of 2 ... | 2003 | 12499084 |
| amelioration of experimental diabetic neuropathy and gastropathy in rats following oral administration of plant (eugenia jambolana, mucuna pruriens and tinospora cordifolia) extracts. | extract of m. charantia (200 mg/kg), e. jambolana (200 mg/kg), m. pruriens (200 mg/kg) and t. cordifolia (400 mg/kg) was administered for 50 days in stz induced diabetic mice, the plasma glucose concentration was reduced by 24.4, 20.84, 7.45 and 9.07% respectively. tail flick latency (tfl) and gastric transit percentage were significantly higher in diabetic controls versus normal controls. m. charantia and e. jambolana modified it favorably while m. pruriens and t. cordifolia did not exert any f ... | 2002 | 12635695 |
| hypoglycaemic and hypolipidemic effect of ethanolic extract of seeds of eugenia jambolana in alloxan-induced diabetic rabbits. | the hypoglycaemic and hypolipidemic effect of ethanolic extract obtained from seeds of e. jambolana was investigated in alloxan-induced diabetic rabbits. hypoglycaemic activity was assessed by reduction in fasting blood glucose (fbg) at 90min and also fall in peak blood glucose during glucose tolerance test (gtt) in sub-diabetic and mild diabetic (md) rabbits, but in severe diabetic (sd) rabbits by reduction in fbg at 90min. ethanolic extract (100mg/kg body weight) when given orally to sub-diabe ... | 2003 | 12639741 |
| inhibitory role of syzygium cumini on autacoid-induced inflammation in rats. | the ethanolic extract of syzygium cumini bark has been reported to possess anti-inflammatory activity in our previous studies. the present study is an attempt to elucidate the anti-inflammatory activity of s. cumini bark against inflammation induced by individual autacoid insult. histamine (1 mg/ml), 5-ht (1 mg/ml), bradykinin (0.02 mg/ml) and pge2 (0.001 mg/ml) were used as inflammogens. one of these agents (0.1 ml) was injected s.c. into the right hind paw of each rat. the ethanolic extract of ... | 2002 | 12683225 |
| hypoglycaemic effect of defatted seeds and water soluble fibre from the seeds of syzygium cumini (linn.) skeels in alloxan diabetic rats. | the effect of feeding orally along with diet of different fractions obtained from the seeds of s. cumini was tried on fasting blood glucose and glucose tolerance in normal and alloxan diabetic rats. the quantitative determination showed that s. cumini seeds contained 40% of water soluble gummy fibre and 15% of water insoluble neutral detergent fibre (ndf). this study demonstrated that feeding for 21 days of the diets containing 15% powdered unextracted (intact) seeds containing water soluble gum ... | 2002 | 12693701 |
| evaluation of the radioprotective effect of the leaf extract of syzygium cumini (jamun) in mice exposed to a lethal dose of gamma-irradiation. | the effects of various concentrations (5, 10, 20, 30, 40, 50, 60, and 80 mg/kg body weight (b.wt.) of the leaf extracts of syzygium cumini linn. and eugenia cumini (sce, black plum, jamun, family myrtaceae) on the radiation-induced sickness and mortality in mice exposed to 10 gy gamma-irradiation were studied. the treatment of mice with different doses of sce, consecutively for five days before irradation, delayed the onset of mortality and reduced the symptoms of radiation sickness when compare ... | 2003 | 12866620 |
| photoelectrochemical solar cell using extract of eugenia jambolana lam as a natural sensitizer. | the extract of jambol o (java plum), eugenia jambolana lam, was used as a natural sensitizer of a wide band-gap semiconductor (tio2) in photoelectrochemical solar cells. the natural dye, adsorbed onto the semiconductor surface, absorbs visible light and promotes electron transfer across the dye/semiconductor interface. photogenerated current and voltage as high as 2.3 ma and 711 mv, respectively, were obtained and effective conversion of visible light into electricity was achieved. the use of a ... | 2003 | 12894301 |
| decayed wood of syzygium cumini and ficus religiosa living trees in delhi/new delhi metropolitan area as natural habitat of cryptococcus neoformans. | the isolation is reported of cryptococcus neoformans var. gattii and c. n. var. neoformans from decayed wood inside trunk hollows of syzygium cumini and of c. n. var. neoformans from ficus religiosa trees in the delhi/new delhi metropolitan area. fourteen of sixty-six (21%) s. cumini trees investigated proved to be positive, seven for each variety. the two varieties never co-occurred in the same hollow. c. n. var. neoformans was also isolated from three of seventeen ficus religiosa-trees. two of ... | 2003 | 12964711 |
| the gastroprotective effect of tannins extracted from duhat (syzygium cumini skeels) bark on hcl/ethanol induced gastric mucosal injury in sprague-dawley rats. | the gastroprotective effect of quantified tannins (13.4%) from syzygium cumini was determined. gastric mucosal damage was induced in sixty eight rats by oral gavage administration of hcl/ethanol solution. for macroscopic and microscopic studies, 30 rats were divided into three groups consisting of a negative control, an omeprazole group and a tannins group. there was no significant difference in the number, size and surface area of macroscopic lesions between the three groups. microscopic examin ... | 2003 | 14724349 |
| hypoglycemic activity of inorganic constituents in eugenia jambolana seed on streptozotocin-induced diabetes in rats. | medicinal herbs used in indigenous medicines for the management of diabetes mellitus contain both organic and inorganic constituents. some of these inorganic trace elements possess antidiabetic properties, which accounts for the activity of medicinal herbs. the aim of this study was to analyze the inorganic trace elements present in eugenia jambolana seeds and to evaluate the hypoglycemic activity of the inorganic part of e. jambolana seeds on streptozotocin-induced diabetes. the seeds of e. jam ... | 2004 | 15235149 |
| anti-diabetic activity of eugenia jambolana seed kernels on streptozotocin-induced diabetic rats. | the present study evaluated the hypoglycemic activity of different parts of eugenia jambolana seeds such as whole seed, kernel, and seed coat on streptozotocin-induced diabetic rats. administration of the ethanolic extract of kernel at a concentration of 100 mg/kg of body weight significantly decreased the levels of blood glucose, blood urea, and cholesterol, increased glucose tolerance and levels of total proteins and liver glycogen, and decreased the activities of glutamate oxaloacetate transa ... | 2004 | 15298766 |
| protective effect of eugenia jambolana seed kernel on tissue antioxidants in streptozotocin-induced diabetic rats. | oxidative stress plays an important role in chronic complications of diabetes. in the present study the antioxidant effect of oral administration of ethanolic extract of eugenia jambolana seed kernel on tissue antioxidant enzymes and lipid peroxidation in liver and kidney of streptozotocin-induced diabetic rats was evaluated. administration of seed kernel to diabetic rats significantly decreased the levels of blood glucose, glycosylated hemoglobin and increased body weight gain, plasma insulin a ... | 2004 | 15305024 |
| effect of eugenia jambolana seed kernel on antioxidant defense system in streptozotocin-induced diabetes in rats. | increased oxidative stress has been suggested to be involved in the pathogenesis and progression of diabetic tissue damage. the aim of this study was to investigate the effect of ethanolic extract of eugenia jambolana seed kernel on antioxidant defense systems of plasma and pancreas in streptozotocin-induced diabetes in rats. the levels of glucose, vitamin-c, vitamin-e, ceruloplasmin, reduced glutathione and lipidperoxides were estimated in plasma of control and experimental groups of rats. the ... | 2004 | 15369706 |
| the evaluation of nitric oxide scavenging activity of certain indian medicinal plants in vitro: a preliminary study. | the plant extracts of 17 commonly used indian medicinal plants were examined for their possible regulatory effect on nitric oxide (no) levels using sodium nitroprusside as an no donor in vitro. most of the plant extracts tested demonstrated direct scavenging of no and exhibited significant activity. the potency of scavenging activity was in the following order: alstonia scholaris > cynodon dactylon > morinda citrifolia > tylophora indica > tectona grandis > aegle marmelos (leaf) > momordica char ... | 2004 | 15383230 |
| antihyperglycaemic and antioxidant effect of hyponidd, an ayurvedic herbomineral formulation in streptozotocin-induced diabetic rats. | hyponidd is a herbomineral formulation composed of the extracts of ten medicinal plants ( momordica charantia, melia azadirachta, pterocarpus marsupium, tinospora cordifolia , gymnema sylvestre, enicostemma littorale, emblica officinalis, eugenia jambolana, cassia auriculata and curcuma longa). we have investigated hyponidd for its possible antihyperglycaemic and antioxidant effect in diabetic rats. rats were rendered diabetic by streptozotocin (stz) (45 mg kg(-1) body weight). oral administrati ... | 2004 | 15525451 |
| fruit of the jambolan tree (eugenia jambolana lam.) and experimental diabetes. | the fruit of indian eugenia jambolana have been shown to have therapeutic properties, but because the therapeutic potential of a plant is related to the geographic region in which the plant was grown and to the part of the plant used, we investigated brazilian eugenia jambolana fruit using the same preparation and experimental methods as have been used in india. the well-established metabolic cage model was used to evaluate the physiological and metabolic parameters associated with streptozotoci ... | 2005 | 15588649 |
| efficacy of swabbing versus a conventional technique for isolation of cryptococcus neoformans from decayed wood in tree trunk hollows. | the efficacy of swabbing versus a conventional sedimentation technique was evaluated for sampling of decayed wood in tree trunk hollows for isolation of cryptococcus neoformans. of 52 samples of decayed wood, bark or other plant debris originating from 35 living trees, 42 wood samples yielded c. neoformans. the positive samples included 40 collected from 31 syzygium cumini trees growing along roadsides in old delhi, whereas the remaining two were from inside tree trunk fissures of ficus religios ... | 2005 | 15712609 |
| preclinical evaluation of the antidiabetic effect of eugenia jambolana seed powder in streptozotocin-diabetic rats. | the world is facing an explosive increase in the incidence of diabetes mellitus and cost-effective complementary therapies are needed. the effects of eugenia jambolana, a household remedy for diabetes, were studied. streptozotocin diabetic female albino wistar rats weighing 150-200 g (n = 6) were fed e. jambolana seed powder (250, 500 or 1000 mg/kg) for 15 days. diabetic rats fed 500 and 1000 mg/kg seed powder showed an increase in body weight on day 20 in relation to day 5 (6 +/- 4.7, 9 +/- 7.8 ... | 2005 | 15761627 |
| influence of seed extract of syzygium cumini (jamun) on mice exposed to different doses of gamma-radiation. | the radioprotective activity of the hydroalcoholic extract of jamun seeds (sce) was studied in mice exposed to different doses of gamma radiation. the mice were injected with 0, 5, 10, 20, 40, 60, 80, 100, 120, 140 or 160 mg/kg body weight of sce, before exposure to 10 gy of gamma radiation, to select the optimum dose of radiation protection. the 80 mg/kg sce was found to offer highest protection, therefore, further studies were carried out using this dose. the drug was more effective when admin ... | 2005 | 15802860 |
| antihyperlipidemic effect of eugenia jambolana seed kernel on streptozotocin-induced diabetes in rats. | abnormalities in lipid profile are one of the most common complications in diabetes mellitus, which is found in about 40% of diabetics. in the present study, anti-hyperlipidemic efficacy of eugenia jambolana seed kernel (ejs-kernel) was evaluated in streptozotocin (stz)-induced diabetic rats and the efficacy was compared with standard hypoglycemic drug, glibenclamide. the effect of oral administration of ethanolic extract of ejs-kernel (100 mg/kg body weight) was examined on the levels of choles ... | 2005 | 15964674 |
| effect of the extracts and fractions of baccharis trimera and syzygium cumini on glycaemia of diabetic and non-diabetic mice. | in the present study, we investigated the effects of extracts and fractions of baccharis trimera and syzygium cumini on glycaemia of diabetic and non-diabetic mice. crude ethanolic extracts and aqueous and butanolic fractions of the aerial parts of baccharis trimera and leaves of syzygium cumini were evaluated. none of the extracts or fractions (200 or 2000 mg/kg, per os) induced any effect after acute administration. seven-day treatment with crude ethanolic and aqueous and butanolic fractions ( ... | 2005 | 16055289 |
| phenolic contents and antioxidant activity of some food and medicinal plants. | to identify promising sources of antioxidants, some food and medicinal plants were studied for total phenolic contents and antioxidant activity. the leaves, bark and fruits of terminalia arjuna, terminalia bellerica, terminalia chebula and terminalia muelleri, the leaves and fruits of phyllanthus emblica, and the seeds of syzygium cumini were found to have high total phenolic contents (72.0-167.2 mg/g) and high antioxidant activity (69.6-90.6%). leaves of eucalyptusglobulus were a rich source of ... | 2005 | 16096138 |
| effect of dianex, a herbal formulation on experimentally induced diabetes mellitus. | dianex, a polyherbal formulation consisting of the aqueous extracts of gymnema sylvestre, eugenia jambolana, momordica charantia azadirachta indica, cassia auriculata, aegle marmelose, withania somnifera and curcuma longa was screened for hypoglycemic activity in normal and streptozotocin induced diabetic mice. dianex was administered in different doses of 100-500 mg/kg/day orally in acute (6 h) and long-term (6 weeks) studies. blood glucose levels were checked 2-6 h after treatment in acute stu ... | 2005 | 16106394 |
| comparative anti-hyperglycemic potentials of medicinal plants. | validation of the ethnobotanical use of the leaves of artemisia vulgaris linn. (compositae), eucalyptus tereticornis sm. (myrtaceae), solanum nigrum linn. (solanaceae), and vitex negundo linn. (verbenaceae); stems of nopalea cochinellifera (linn.) salm-dyck (cactaceae); roots of imperata cylindrica beauv. (gramineae); dried bark of syzygium cumini (linn.) skeels (myrtaceae) as anti-diabetic agents using the oral glucose tolerance test showed that only the bark of syzygium cumini and the leaves o ... | 2006 | 16253452 |
| sos-red fluorescent protein (rfp) bioassay system for monitoring of antigenotoxic activity in plant extracts. | an optical antigenotoxicity assay using genetically engineered red fluorescent bacteria is presented. exposure of escherichia coli rs4u to genotoxicants [mitomycin c (mmc), nalidixic acid (na) and hydrogen peroxide (hp)] resulted in phenotypic red fluorescence proportional to the concentration of the inducer. except for tannic acid (ta), co-treatment of the genotoxicant-activated bacteria with ascorbic acid (aa) and aqueous plant extracts (mangifera indica, psidium guajava and syzygium cumini) a ... | 2006 | 16321516 |
| antihyperglycemic effect of the fruit-pulp of eugenia jambolana in experimental diabetes mellitus. | the oral antihyperglycemic effect of the water and ethanolic extracts of the fruit-pulp of eugenia jambolana (ej) was investigated in alloxan-induced diabetic with fasting blood glucose between 120 and 250 mg/dl as well as severely diabetic rabbits (fasting blood glucose above 250 mg/dl). water extract was found to be more effective than the ethanolic extract in reducing fasting blood glucose and improving blood glucose in glucose tolerance test. chromatographic purification of the water extract ... | 2006 | 16386863 |
| in vitro glucose uptake activity of aegles marmelos and syzygium cumini by activation of glut-4, pi3 kinase and ppargamma in l6 myotubes. | the purpose of the present study is to investigate the effect of methanolic extracts of aegles marmelos and syzygium cumini on a battery of targets glucose transporter (glut-4), peroxisome proliferator activator receptor gamma (ppargamma) and phosphatidylinositol 3' kinase (pi3 kinase) involved in glucose transport. a. marmelos and s. cumini are anti-diabetic medicinal plants being used in indian traditional medicine. different solvent extracts extracted sequentially were analysed for glucose up ... | 2006 | 16716914 |
| production of tannase from aspergillus ruber under solid-state fermentation using jamun (syzygium cumini) leaves. | tannase producing fungal strains were isolated from different locations including garbages, forests and orchards, etc. the strain giving maximum enzyme yield was identified to be aspergillus ruber. enzyme production was studied under solid state fermentation using different tannin rich substrates like ber leaves (zyzyphus mauritiana), jamun leaves (syzygium cumini), amla leaves (phyllanthus emblica) and jawar leaves (sorghum vulgaris). jamun leaves were found to be the best substrate for enzyme ... | 2007 | 16870410 |
| the efficacy of herbal medicines in clinical models: the case of jambolan. | a large proportion of drugs employed in clinical practice come from plants. the development of new medical agents is a lengthy and time-consuming process, with the identification of extracts with putative therapeutic effects, the isolation of active ingredients and pre-clinical studies to investigate their pharmacological profile. we propose a shortcut in this sequence of procedures, testing first if the extracts, in the way they are used by patients, have efficacy in clinical models. on the one ... | 2006 | 16963214 |
| distribution of cryptococcus gattii and cryptococcus neoformans in decayed trunk wood of syzygium cumini trees in north-western india. | the aim of this study is to report the regional distribution of cryptococcus. gattii and cryptococcus. neoformans in decayed wood inside trunk hollows of syzygium cumini trees (java plum, indian black berry) investigated in amritsar (panjab), meerut cantt. and bulandshahr (uttar pradesh) and delhi, in north-western india. two hundred and seventeen wood samples collected from 74 s. cumini trees were investigated. this includes 7 known positive s. cumini trees in delhi subjected to a mycological s ... | 2006 | 17071556 |
| protection of testicular dysfunctions by mtec, a formulated herbal drug, in streptozotocin induced diabetic rat. | single injection of streptozotocin (stz) resulted diabetes mellitus which was reflected here by the levels of fasting blood glucose and serum insulin. moreover, this experimental diabetes also resulted testicular dysfunctions evaluated by count, viability and motility of sperm as well as by the activities of key enzymes for androgen synthesis. diabetes induced testicular oxidative stress has been indicated here by the monitoring of testicular peroxidase and catalase activities as well as by quan ... | 2007 | 17202665 |
| pharmacological study of anti-allergic activity of syzygium cumini (l.) skeels. | myrtaceae is a plant family widely used in folk medicine and syzygium and eugenia are among the most important genera. we investigated the anti-allergic properties of an aqueous leaf extract of syzygium cumini (l.) skeels (sc). hplc analysis revealed that hydrolyzable tannins and flavonoids are the major components of the extract. oral administration of sc (25-100 mg/kg) in swiss mice (20-25 g; n = 7/group) inhibited paw edema induced by compound 48/80 (50% inhibition, 100 mg/kg; p <or= 0.05) an ... | 2007 | 17225003 |
| antileishmanial and antifungal activity of plants used in traditional medicine in brazil. | the antileishmanial and antifungal activity of 24 methanol extracts from 20 plants, all of them used in the brazilian traditional medicine for the treatment of several infectious and inflammatory disorders, were evaluated against promastigotes forms of two species of leishmania (l. amazonensis and l. chagasi) and two yeasts (candida albicans and cryptococcus neoformans). among the 20 tested methanolic extracts, those of vernonia polyanthes was the most active against l. amazonensis (ic(50) of 4 ... | 2007 | 17234373 |
| effect of the aqueous extract of syzygium cumini on carbon tetrachloride-induced hepatotoxicity in rats. | the aim of this study was to evaluate the effect of the aqueous syzygium cumini leaf extract, given either as a single dose or by 7 days of pretreatment, on hepatotoxicity induced by carbon tetrachloride in rats. blood samples obtained after treatments were measured for aspartate aminotransferase (ast) and alanine aminotransferase (alt). a significant increase in the ast and alt activities occurred after carbon tetrachloride administration alone, which was significantly lowered by preadministrat ... | 2007 | 17450508 |
| antifungal susceptibility of cryptococcus neoformans and cryptococcus gattii isolates from decayed wood of trunk hollows of ficus religiosa and syzygium cumini trees in north-western india. | we present antifungal susceptibility data on environmental isolates of cryptococcus neoformans (serotype a, n=117) and cryptococcus gattii (serotype b, n=65) cultured from decayed wood of trunk hollows of ficus religiosa and syzygium cumini trees. | 2007 | 17553813 |
| in vitro hypoglycemic activity of methanolic extract of some indigenous plants. | pakistan is rich in medicinally important plants and has ancient herbal treatment methods. present work is based on the study of six indigenous plants eugenia jambolana, lawsonia inermis, momordica charantia, morus alba, nigella sativa and trigonella foenum graecum which show the inhibitory effect of glucose utilization, and are in use as hypoglycemic agents of varying degree in traditional system of medicine. the glucose uptake activity of (methanolic extracts) of these plants was tested in vit ... | 2007 | 17604247 |
| ecological niche of cryptococcus neoformans var. grubii and cryptococcus gattii in decaying wood of trunk hollows of living trees in jabalpur city of central india. | cryptococcus neoformans var. grubii and c. gattii were repeatedly isolated from decaying wood of trunk hollows in living trees growing in jabalpur city in central india. the isolation of c. gattii has been reported from decayed wood inside trunk hollow of tamarindus indica (15.6%), mangifera indica (2.2%), pithecolobium dulce (12.5%), syzygium cumini (14%), and one from bark of s. cumini. c. n. var. grubii was isolated from decaying wood debris of t. indica (4.4%), m. indica (13.3%), terminalia ... | 2007 | 17661160 |
| dioxin uptake by indian plant species. | dioxins like various gaseous pollutants and aerosols can be scavenged by appropriate vegetative greenbelts. based on their stomatal properties and the models for contaminant uptake, uptake of dioxin (2,3,7,8-tcdd) by three important indian plant species, viz. eugenia jambolana (jamun), azadirachta indica (neem) and ficus religiosa (peepal), has been estimated. 2,3,7,8-tcdd is a contaminant with severe harmful ecological ramifications. computations show that ficus religiosa has highest uptake cap ... | 2008 | 17874332 |
| effects of ethanolic extract of syzygium cumini (linn) seed powder on pancreatic islets of alloxan diabetic rats. | the ethanolic extract of seeds of s. cumini increased body weight and decreased blood sugar level in alloxan diabetic albino rats. level of significance for decrease in blood sugar after feeding alcoholic extract of s. cumini seeds in various doses was highly significant. the extract feeding showed definite improvement in the histopathology of islets. the most important finding is that the blood sugar level, which once dropped to normal levels after extract feeding was not elevated when extract ... | 2007 | 17948734 |
| effect of ethanolic extract of eugenia jambolana seeds on gastric ulceration and secretion in rats. | eugenia jambolana (jamun) fruit has been reported to give soothing effect on human digestive system. present study includes the effect of ethanolic extract of seeds of e. jambolana (eje) against gastric ulcers induced by 2 h cold restraint stress (crs), aspirin (asp, 200 mg/kg, 4 h), 95% ethanol (etoh, 1 ml/200 g, 1 h) and 4 h pylorus ligation (pl) in rats. to ascertain the mechanism of action of eje, its effect was studied on mucosal offensive acid-pepsin secretion, lipid peroxidation (lpo, fre ... | 2007 | 18175656 |
| radioprotective potential of plants and herbs against the effects of ionizing radiation. | ionizing radiations produce deleterious effects in the living organisms and the rapid technological advancement has increased human exposure to ionizing radiations enormously. there is a need to protect humans against such effects of ionizing radiation. attempts to protect against the deleterious effects of ionizing radiations by pharmacological intervention were made as early as 1949 and efforts are continued to search radioprotectors, which may be of great help for human application. this revi ... | 2007 | 18188408 |
| in vitro antiviral activity of plant extracts on goatpox virus replication. | four plants having known medicinal properties were screened for inhibition of goatpox virus (gtpv) replication in vitro. of the 4 plants, extract of acacia arabica (babul) and eugenia jambolana (jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (cpe) inhibition assays. inhibition of gtpv virus replication was further confirmed by pcr and sybr green based quantitative rea ... | 2008 | 18335810 |
| alpha-glucosidase inhibitory activity of syzygium cumini (linn.) skeels seed kernel in vitro and in goto-kakizaki (gk) rats. | syzygium cumini seed kernel extracts were evaluated for the inhibition of alpha-glucosidase from mammalian (rat intestine), bacterial (bacillus stearothermophilus), and yeast (saccharomyces cerevisiae, baker's yeast). in vitro studies using the mammalian alpha-glucosidase from rat intestine showed the extracts to be more effective in inhibiting maltase when compared to the acarbose control. since acarbose is inactive against both the bacterial and the yeast enzymes, the extracts were compared to ... | 2008 | 18374320 |
| indian herbs and herbal drugs used for the treatment of diabetes. | traditional medicines derived from medicinal plants are used by about 60% of the world's population. this review focuses on indian herbal drugs and plants used in the treatment of diabetes, especially in india. diabetes is an important human ailment afflicting many from various walks of life in different countries. in india it is proving to be a major health problem, especially in the urban areas. though there are various approaches to reduce the ill effects of diabetes and its secondary complic ... | 2007 | 18398493 |
| hypoglycemic and hypolipidemic effects of flavonoid rich extract from eugenia jambolana seeds on streptozotocin induced diabetic rats. | the hypoglycemic and hypolipidemic effects of flavonoid rich extract obtained from seeds of eugenia jambolana (ej) was analyzed in streptozotocin induced diabetic rats. hypoglycemic activity was assessed by reduction in fasting blood glucose (fbg) and peak blood glucose level within 60 min of glucose tolerance test (gtt) in mild and severe diabetic (md and sd respectively) rats. different biochemical parameters like glycogen biosynthesis, glucose homeostatic enzyme (glucose-6-phosphatase, hexoki ... | 2008 | 18474411 |
| efficient amelioration of carbon tetrachloride induced toxicity in isolated rat hepatocytes by syzygium cumini skeels extract. | syzygium cumini, indian black plum or java plum, is a rich source for anthocyanins (230 mg/100g dw) showing high antioxidant activity in vitro. in the following study it is further demonstrated that s. cumini peel extract rich in anthocyanins (sca) offers considerable protection against carbon tetrachloride (ccl(4))-induced damage in rat hepatocytes. sca itself being non-toxic to primary rat hepatocytes at concentrations ranging from 50 to 500 ppm, was found to suppress ccl(4)-induced ldh leakag ... | 2008 | 18538978 |
| therapeutic effect of ferulic acid, an ethereal fraction of ethanolic extract of seed of syzygium cumini against streptozotocin-induced diabetes in male rat. | diabetic therapeutic and antioxidative effects of an ethereal fraction of the ethanolic extract of the seed of syzygium cumini was studied in streptozotocin (stz)-induced diabetic rats. diabetes resulted in a significant elevation in the fasting blood glucose level and in the activity of hepatic glucose-6-phosphatase. there was diminution in the levels of glycogen in the liver and skeletal muscle along with diminution in the activities of hepatic glucose-6-phosphate dehydrogenase, catalase and p ... | 2008 | 18560627 |
| seasonal variations of airborne pollen in allahabad, india. | using a burkard 7-day volumetric sampler a survey of airborne pollen grains in allahabad was carried out from december 2004--november 2005 to assess the qualitative and quantitative occurrence of pollen grains during different months of the year, and to characterize the pollen seasons of dominant pollen types in the atmosphere of allahabad. 80 pollen types were identified out of the total pollen catch of 3,416.34 pollen grains/m(3). bulk of the pollen originated from anemophilous trees and grass ... | 2008 | 19061265 |
| eugenia jambolana lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. | the ripe purple berries of the native indian plant eugenia jambolana lam., known as jamun, are popularly consumed and available in the united states in florida and hawaii. despite the growing body of data on the chemopreventive potential of edible berry extracts, there is paucity of such data for jamun fruit. therefore our laboratory initiated the current study with the following objectives: (1) to prepare a standardized jamun fruit extract (jfe) for biological studies and (2) to investigate the ... | 2009 | 19166352 |
| environmental isolation of cryptococcus neoformans and cryptococcus gattii from living trees in guindy national park, chennai, south india. | we report for the first time the environmental isolation of cryptococcus neoformans from decaying wood and bark debris of living trees in guindy national park, chennai, south india. of the 40 trees screened, four isolates of cryptococcus species were recovered of which two were cryptococcus gattii, one was c. neoformans and one was untypable. the isolation of c. neoformans from eucalyptus globulus and c. gattii from cassia marginata in this study constitutes the first record of the natural occur ... | 2010 | 19389069 |
| in vitro phototoxic activity of eugenia jambolana l. and hyptis martiusii benth. | ethanol extracts from hyptis martiusii and eugenia jambolana were assayed for light-mediated activity against strains of staphylococcus aureus, escherichia coli and pseudomonas aeruginosa. duplicate assays were conducted with and without exposure to uv-a radiation to test for light-activated or light-enhanced activity. both extracts showed activity against at least two bacterial strains, but h. martiusii was the most active extract, being active against all strains of s. aureus and e. coli. the ... | 2009 | 19409807 |
| antifungal activity of syzygium cumini against ascochyta rabiei-the cause of chickpea blight. | aqueous, ethanol and n-hexane extracts from leaves, fruit, root-bark and stem-bark of syzygium cumini (l.) skeels were tested for their antifungal activity against ascochyta rabiei (pass.) lab., the cause of blight disease of the chickpea (cicer arietinum l.). different concentrations, namely 1, 2, ..., 5% of both aqueous and the two organic solvent extracts were used in this study. aqueous extracts of all the four test plant parts, namely leaves, fruit, stem-bark and root-bark, showed significa ... | 2010 | 19588279 |
| antihyperglycemic, antihyperlipidemic and antioxidant effects of dihar, a polyherbal ayurvedic formulation in streptozotocin induced diabetic rats. | present investigation was undertaken to evaluate antihyperglycemic, antihyperlipidemic and antioxidant activities of dihar, a polyherbal formulation containing drugs from eight different herbs viz., syzygium cumini, momordica charantia, emblica officinalis, gymnema sylvestre, enicostemma littorale, azadirachta indica, tinospora cordifolia and curcuma longa in streptozotocin (stz, 45 mg/kg iv single dose) induced type 1 diabetic rats. stz produced a significant increase in serum glucose, choleste ... | 2009 | 19761040 |
| ulcer healing properties of ethanolic extract of eugenia jambolana seed in diabetic rats: study on gastric mucosal defensive factors. | diabetes has been reported to cause an increase in offensive and decrease in defensive gastric mucosal factors, the imbalance of which can cause ulceration and delay the ulcer healing. eugenia jambolana has been documented to have both antidiabetic and antiulcer activities. the present study evaluates the effects of ethanolic extract of e. jambolana on gastric ulcer healing and on rat gastric mucosal defensive factors in gastric ulcer with co-occurring diabetes. e. jambolana extract was administ ... | 2009 | 19810572 |
| complementary and comparative study on hypoglycemic and antihyperglycemic activity of various extracts of eugenia jambolana seed, momordica charantia fruits, gymnema sylvestre, and trigonella foenum graecum seeds in rats. | in present study, we investigated hypoglycemic and antihyperglycemic potential of five extracts (water, ethanol, methanol, hexane, and chloroform) of four plants (i.e., seeds of eugenia jambolana, fruits of momordica charantia, leaves of gymnema sylvestre, and seeds of trigonella foenum graecum) alone and/or in combination with glimepiride in rats. ethanol extract of e. jambolana, water extract of m. charantia, ethanol extract of g. sylvestre, and water extract of t. graecum exhibited highest hy ... | 2010 | 19904502 |
| ellagic acid derivatives from syzygium cumini stem bark: investigation of their antiplasmodial activity. | bioguided fractionation of syzygium cumini (myrtaceae) bark decoction for antiplasmodial activity was performed, leading to the isolation of three known ellagic acid derivatives (ellagic acid, ellagic acid 4-o-alpha-l-2"-acetylrhamnopyranoside, 3-o-methylellagic acid 3'-o-alpha-l-rhamnopyranoside), as well as the new derivative 3-o-methylellagic acid 3'-o-beta-d-glucopyranoside. activity investigation was based on the reduction of p. falciparum (pfk1) parasitaemia in vitro and the inhibition of ... | 2009 | 19911574 |
| effects of fruit ellagitannin extracts, ellagic acid, and their colonic metabolite, urolithin a, on wnt signaling. | recent data suggest that ellagitannins (ets), a class of hydrolyzable tannins found in some fruits and nuts, may have beneficial effects against colon cancer. in the stomach and gut, ets hydrolyze to release ellagic acid (ea) and are converted by gut microbiota to urolithin a (ua; 3,8-dihydroxy-6h-dibenzopyran-6-one) type metabolites, which may persist in the colon through enterohepatic circulation. however, little is known about the mechanisms of action of either the native compounds or their m ... | 2010 | 20014760 |
| diabetic therapeutic effects of ethyl acetate fraction from the roots of musa paradisiaca and seeds of eugenia jambolana in streptozotocin-induced male diabetic rats. | the folklore medicine of primitive people has been greatly appreciated for centuries. many researchers study the curative efficiency and mode of action of various medicinal plants. serum glucose level, lipid profile, glucose tolerance, hepatic and muscle glycogen contents as well as the activities of hepatic hexokinase and glucose-6-phosphatase recovered significantly after oral administration of ethyl acetate fractions of eugenia jambolana (e. jambolana) or musa paradisiaca (m. paradisiaca) in ... | 2009 | 20094640 |
| antidiabetic and antiulcer effects of extract of eugenia jambolana seed in mild diabetic rats: study on gastric mucosal offensive acid-pepsin secretion. | diabetes has been reported to increase propensity to peptic ulceration through its effect both on offensive and defensive mucosal factors. seeds of eugenia jambolana (ej) have been reported to have both antidiabetic as well as ulcer protective effects. the present study evaluates the antidiabetic effects of ethanolic extract of dried seed kernel of eugenia jambolana (eje) and its comparative effect on gastric ulceration and acid-pepsin secretion with standard antisecretory fl-blocker. ranitidine ... | 2009 | 20112817 |
| hepatoprotective activity of eugenia jambolana lam. in carbon tetrachloride treated rats. | to estimate the hepatoprotective effects of the methanolic seed extract of eugenia jambolana lam. (myrtaceae), in wistar albino rats treated with carbon tetrachloride (ccl(4)). | 2009 | 20177577 |
| histological effects of eugenia jambolana seed extract on liver of adult albino rats. | the therapeutic value of eugenia jambolana, commonly known as 'jamun' in hindi, has been recognized in different system of traditional medicine for the treatment of various conditions. its seeds are used for the treatment of diabetes mellitus and hyperlipedemia by reducing the lipid levels in the body; this action is presumed to be due to blocking the action of enzyme 3-hydroxyl methyl glutaryl (hmg-coa reductase in the liver. herbal drugs are getting into use with the notion that these are rela ... | 2009 | 20364766 |
| vibriocidal activity of certain medicinal plants used in indian folklore medicine by tribals of mahakoshal region of central india. | screening of the medicinal plants and determination of minimum inhibitory concentration (mic) against vibrio cholerae and vibrio parahaemolyticus. | 2009 | 20442821 |
| determination of antibacterial and antioxidant potential of some medicinal plants from saurashtra region, india. | many plants used in saurashtra folk medicine have been reported to exhibit high antibacterial and antioxidant activities. in the present study, some parts of five plants, guazuma ulmifolia l., manilkara zapota l., melia azedarach l., syzygium cumini l. and wrightia tomentosa r.& s., were evaluated for their antibacterial activity, total phenol content, flavonoid content, 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity and phytochemical analysis, using successive extraction by cold ... | 2009 | 20502546 |
| effect of alcoholic extracts of indian medicinal plants on the altered enzymatic activities of diabetic rats. | in present study, the effect of alcoholic extract of momordica charantia, aegle marmelos and eugenia jambolana was studied on serum glutamic oxaloacetate transminase and serum glutamic pyruvate transminase activities and on serum urea, total protein and albumin concentrations of streptozotocin diabetic rats. diabetes in rats was induced by single dose of streptozotocin (30 mg/kg i. p.). on confirming the diabetes after 48 h of injection, alcoholic extracts of three plants were administered orall ... | 2009 | 20502588 |
| attenuation of renal dysfunction by anti-hyperglycemic compound isolated from fruit pulp of eugenia jambolana in streptozotocin-induced diabetic rats. | the renal protective effect of an active principle isolated from the aqueous extract of fruit pulp of eugenia jambolana was investigated in streptozotocin (45 mg/kg body weight)-induced severely diabetic rats (fbg > or = 300 mg/dl). for isolation of active principle, crude aqueous extract of e. jambolana fruit pulp was subjected to purification by ion-exchange column chromatography, which yielded a partially purified compound (fii), which on further purification by rechromatography gave a purifi ... | 2010 | 20521620 |
| chemopreventive action of syzygium cumini on dmba-induced skin papillomagenesis in mice. | syzygium cumini l. is widely used for the treatment of diabetes in various parts of india. the protective efficacy of s. cumini seed extract (sce) against peroxidative damage contributing to skin carcinogenesis in swiss albino mice was tested in the present study. a single topical application of 7,12-dimethyl benz(a)anthracene (100 microg/100 microl acetone), followed 2 weeks later by repeated application of croton oil (1% in acetone three times a week) and continued till the end of the experime ... | 2010 | 20593968 |
| activity of eugenia jambolana, an ethnomedical plant, against drug-resistant bacteria. | seeds of eugenia jambolana lam. (myrtaceae) are used by many tribes in india to treat diarrhea and dysentery. the crude extracts of seeds of this plant demonstrated zones of inhibition in the range of 14- 21 mm against the isolated beta-lactamase-producing drug-resistant bacteria. the methanol extract showed promising antibacterial activity which was subjected to fractionation. the effective fraction (f2) showed a minimum inhibitory concentration (mic) ranging from 31.75 to 62.5 microg/ml. phyto ... | 2010 | 20645718 |
| toxicological assessments of aqueous extract of eugenia jambolana stem bark. | eugenia jambolana lam. (myrtaceae) is widely used in folk medicine as an antidiabetic, but there is a lack of information about its toxicity, especially for the stem bark. the present study evaluated acute oral and repeated-dose toxicity of the stem bark aqueous extract of eugenia jambolana (ej) in albino mice and wistar rats. in the acute toxicity tests, mice received oral doses of ej extract as 300, 2000, and 5000 mg/kg body weight. mortality, signs of toxicity, body weight, food consumption, ... | 2010 | 20673170 |
| evaluation of traditional indian antidiabetic medicinal plants for human pancreatic amylase inhibitory effect in vitro. | pancreatic α-amylase inhibitors offer an effective strategy to lower the levels of post prandial hyperglycemia via control of starch breakdown. eleven ayurvedic indian medicinal plants with known hypoglycemic properties were subjected to sequential solvent extraction and tested for α-amylase inhibition, in order to assess and evaluate their inhibitory potential on pancreatic α-amylase. analysis of 91 extracts, showed that 10 exhibited strong human pancreatic amylase (hpa) inhibitory potential. o ... | 2010 | 20953430 |
| evaluation of anti-cancer and anti-oxidative potential of syzygium cumini against benzo[a]pyrene (bap) induced gastric carcinogenesis in mice. | syzygium cummini extract (sce) was used in the present study to explore anti-tumor promoting activity in a stomach carcinogenesis model in mice. for this purpose, swiss albino mice were administered with 1 mg of benzo-a-pyrene (bap) in 100?l sesame oil by oral gavage twice a week for 4 consecutive weeks. the animals were sacrificed 14 weeks after the last administration of bap. oral administration of the extract to pre-treated (i.e. sce as 25mg/kg b. wt./ day before bap application for 2 weeks), ... | 2010 | 21039048 |
| syzygium cumini extract decrease adenosine deaminase, 5'nucleotidase activities and oxidative damage in platelets of diabetic patients. | diabetes mellitus, a chronic metabolic disorder, has assumed epidemic proportions and its long-term complications can have devastating consequences. the oxidative stress in diabetes was greatly increased due to prolonged exposure to hyperglycemia and impairment of oxidant/antioxidant equilibrium. syzygium cumini is being widely used to treat diabetes by the traditional practitioners over many centuries. adenosine deaminase (ada) and 5'-nucleotidase (5'nt) are enzymes of purine nucleoside metabol ... | 2010 | 21063110 |
| elimination of deleterious effects of dmba-induced skin carcinogenesis in mice by syzygium cumini seed extract. | the inhibition of tumor incidence by hydro-alcoholic extract of s.cumini seed was evaluated in mice on two stage process of skin carcinogenesis induced by single application of 7, 12-dimethyl benz(a)anthracene (100 μg/100μl of acetone), and 2 weeks later promoted by repeated application of croton oil (1% acetone/thrice in a week) till the end of the experiment (i.e. 16 weeks). oral administration of extract at a dose of 250mg/kg b.wt./day at the pre-initiational stage (i.e. 7 days before and 7 d ... | 2010 | 21147816 |
| antimicrobial potential of some plant extracts against candida species. | the increase in the resistance to antimicrobial drugs in use has attracted the attention of the scientific community, and medicinal plants have been extensively studied as alternative agents for the prevention of infections. the candida genus yeast can become an opportunistic pathogen causing disease in immunosuppressive hosts. the purpose of this study was to evaluate dichloromethane and methanol extracts from mentha piperita, rosmarinus officinalis, arrabidaea chica, tabebuia avellanedae, puni ... | 2010 | 21180915 |
| role of syzygium cumini seed extract in the chemoprevention of in vivo genomic damage and oxidative stress. | ethanopharmacological relevance: the seeds of syzygium cumini, skeels (jamun) are extensively used in india for treatment of diabetes and other ailments. | 2010 | 21182920 |
| protective effects of syzygium cumini seed extract against methylmercury-induced sistemic toxicity in neonatal rats. | syzygium cumini (l.) skeels (sc) belongs to the medicinal plants with an important source of phenolic compounds. sc has been shown to possess antioxidant and anti-inflammatory properties. methylmercury (mehg), a highly toxic environmental pollutant, induces oxidative stress and dysfunction in many cell types. this study was aimed to evaluate the effect of aqueous seed extract of sc (asc) on mehg-induced toxicity in rats. two-day-old rats (p2) received a single dose of mehg (10 mg/kg) and two dos ... | 2011 | 21207116 |
| ethnobotanical survey of medicinal plants commonly used by kani tribals in tirunelveli hills of western ghats, india. | for thousands of years, medicinal plants have played an important role throughout the world in treating and preventing a variety of diseases. kani tribal people in tirunelveli hills still depend on medicinal plants and most of them have a general knowledge of medicinal plants which are used for first aid remedies, to treat cough, cold, fever, headache, poisonous bites and some simple ailments. | 2011 | 21291981 |
| antihyperlipidemic effect of active principle isolated from seed of eugenia jambolana on alloxan-induced diabetic rabbits. | diabetes is accompanied by lipid abnormalities, which contribute significantly to cardiovascular morbidity and mortality in diabetic patients. we previously demonstrated the potent antihyperglycemic activity of the active principle (fraction ii from sephadex lh 20 chromatography [lh ii]) isolated from ethanolic seed extract of eugenia jambolana in diabetic rabbits. in the present study, the efficacy of lh ii was evaluated for its hypolipidemic activity in alloxan-induced mildly diabetic (md) and ... | 2011 | 21370965 |
| anticancer, chemopreventive and radioprotective potential of black plum (eugenia jambolana lam.). | despite good understanding of the molecular basis of the disease and advances in treatment, globally cancer is still a major cause of death. estimates are that it will surpass cardiovascular disease as the leading cause of death, with higher incidences in the developing countries that have minimal resources. chemotherapy and radiotherapy, the two most commonly used treatment modalities, are associated with untoward side effects. this has necessitated the search for alternatives that are effectiv ... | 2011 | 21517226 |