| antiadipogenic activity of isohamnetin 3-o-β-d-glucopyranoside from salicornia herbacea. | in the present study, effect of flavonoid glucopyranoside, isorhamnetin 3-о-β-d-glucopyranoside, from salicornia herbacea on adipogenic differentiation were evaluated in 3t3-l1 adipocytes. confluent 3t3-l1 preadipocytes in medium (0.5 mm methylisobutylxanthine, 0.25 µm dexamethasone, 5 µg/ml insulin, and 10% fetal bovine serum [fbs]) were differentiated into adipocytes for 6 days with/without isorhamnetin 3-о-β-d-glucopyranoside. the presence of isorhamnetin 3-о-β-d-glucopyranoside effectively s ... | 2012 | 22978277 |
| a pks i gene-based screening approach for the discovery of a new polyketide from penicillium citrinum salicorn 46. | salicorn 46, an endophytic fungus isolated from salicornia herbacea torr., was identified as penicillium citrinum based on its internal transcribed spacer and ribosomal large-subunit dna sequences using a type i polyketide synthase (pks i) gene screening approach. a new polyketide, penicitriketo (1), and seven known compounds, including ergone (2), (3β,5α,8α,22e)-5,8-epidioxyergosta-6,9,22-trien-3-ol (3), (3β,5α,8α,22e)-5,8-epidioxyergosta-6,22-dien-3-ol (4), stigmasta-7,22-diene-3β,5α,6α-triol ... | 2014 | 24535256 |
| effect of glasswort (salicornia herbacea l.) on microbial community variations in the vinegar-making process and vinegar characteristics. | three types of nuruk were made from rice, wheat, and a rice-glasswort (6:4) mixture. nuruk, makgeolli, and vinegar were manufactured with rice nuruk (rn), wheat nuruk (wn), and rice-glasswort nuruk (rgn). the saccharifying activity and ethanol productivity of nuruk, polyphenol content in makgeolli, and acetic acid and polyphenol content in the vinegar were increased as the result of the addition of glasswort. the variable region of 18s- or 16s-rdna amplified with genomic dna extracted directly f ... | 2010 | 20890098 |
| 3-caffeoyl, 4-dihydrocaffeoylquinic acid from salicornia herbacea inhibits tumor cell invasion by regulating protein kinase c-delta-dependent matrix metalloproteinase-9 expression. | in this study, we determined the effects of a novel chlorogenic acid, 3-caffeoyl, 4-dicaffeoylquinic acid (cdcq) isolated from salicornia herbacea, on tumor invasion and migration in human fibrosarcoma ht-1080 cells and investigated the possible mechanism(s) involved. cdcq reduced the phorbol myristate acetate (pma)-induced activation of matrix metalloproteinase (mmp)-9 and mmp-2 and inhibited cell invasion and migration. cdcq suppressed pma-induced expression of mmp-9 mrna and protein by suppre ... | 2010 | 20599481 |
| protective mechanisms of 3-caffeoyl, 4-dihydrocaffeoyl quinic acid from salicornia herbacea against tert-butyl hydroperoxide-induced oxidative damage. | salicornia herbacea has been used as a folk medicine for disorders such as constipation, obesity, diabetes, and cancer. recent studies have shown that s. herbacea has antioxidative, anti-inflammatory, immunomodulatory, antihyperglycemic, and antihyperlipidemic activities. in the present work, we investigated the protective effects of the chlorogenic acid derivative, 3-caffeoyl, 4-dihydrocaffeoyl quinic acid (cdcq), which was isolated from s. herbacea, against tert-butyl hydroperoxide (t-bhp)-ind ... | 2009 | 19647727 |
| protective effect of isorhamnetin 3-o-beta-d-glucopyranoside from salicornia herbacea against oxidation-induced cell damage. | isorhamnetin 3-o-beta-d-glucopyranoside (1) was isolated from salicornia herbacea. the inhibitory effects of compound 1 on oxidative stress were evaluated in free-cellular and cellular systems. an increased concentration of compound 1 not only exhibited dose-dependent scavenging activities on the generation of 1,1-diphenyl-2-picrylhydrazyl (dpph), hydroxyl and carbon-centered radicals, but also significantly decreased levels of intracellular reactive oxygen species (ros) in a dose-dependent mann ... | 2009 | 19445998 |
| antioxidative and skin-whitening effect of an aqueous extract of salicornia herbacea. | salicornia herbacea (sh) is a halophyte that grows in the salt marshes along the coastline of south korea, and is known to have antioxidative activity. in this study, the antioxidative and skin-whitening effects of sh aqueous extract were investigated in human dermal fibroblasts (hdfs) and b16 melanoma cells. the water extract of sh had potent antioxidative capacity and protected hdfs from tert-butyl hydroperoxide (tbooh)-induced oxidative stress in a dose-dependent manner. in a cell cycle analy ... | 2009 | 19270393 |
| flavonoid glycosides isolated from salicornia herbacea inhibit matrix metalloproteinase in ht1080 cells. | flavonoid glycosides, isorhamnetin 3-capital o, cyrillic-beta-d-glucoside, and quercetin 3-o-beta-d-glucoside were isolated from salicornia herbacea and their inhibitory effects on matrix metalloproteinase-9 and -2 (mmp-9 and -2) were evaluated in human fibrosarcoma cell line (ht1080). in zymography experiments, these flavonoid glycosides led to the reduction of the expression levels and activities of mmp-9 and -2 without any significant difference between these flavonoid glycosides. protein exp ... | 2008 | 18715546 |
| antioxidant and antithrombus activities of enzyme-treated salicornia herbacea extracts. | this study was attempted to investigate antioxidant and antithrombus activities of water and methanol extracts of enzyme-treated salicornia herbacea (sh)by in vitro assays observing the inhibitory activity of a rat liver microsomal lipid peroxidation, dpph radical scavenging activity, activated partial thromboplastin times (aptt) and thromboplastin times (tt). the water and methanol extracts from enzyme-treated sh inhibited the lipid peroxidation in a dose-dependent manner over a concentration r ... | 2007 | 17536188 |
| synergistic activation of monocytes by polysaccharides isolated from salicornia herbacea and interferon-gamma. | the hot water extract of salicornia herbacea, she, has recently been shown to have strong immunomodulatory activity. in the present study, we purified the polysaccharides, termed shp, from she preparation and examined their immunomodulatory activity alone and in combination with interferon (ifn)-gamma. the combination of shp and ifn-gamma synergistically inhibited the growth of the mouse monocytic cell line, raw 264.7, inducing further differentiation to strongly adherent macrophages. the differ ... | 2007 | 17204386 |
| immunomodulatory activity of polysaccharides isolated from salicornia herbacea. | several types of immunomodulatory polysaccharides originated from plants or mushrooms have been used as immunotherapeutic agents in the treatment of cancers. here, we describe an immunomodulatory polysaccharide that cannot only activate monocytic cells strongly, but also induce differentiation of monocytic cells into macrophages. high molecular weight substances, she, were isolated from salicornia herbacea, which has been used to treat a variety of diseases including cancers in traditional orien ... | 2006 | 16846839 |
| the role of salicornia herbacea in ovariectomy-induced oxidative stress. | ovarian hormone deficiency increases the generation of reactive oxygen species. their excess induces oxidative stress, which results in the cell damage or death. it causes the aging diseases-atherosclerosis, rheumatoid arthritis, osteoporosis, etc. ovariectomized rats are used as oxidative stress models. we verified the effects of ovariectomy-induced oxidative stress on free radical production as evaluated by dpph elimination, lipoperoxidation evaluated by malondialdehyde levels, and antioxidant ... | 2006 | 16819158 |
| salicornia herbacea prevents high fat diet-induced hyperglycemia and hyperlipidemia in icr mice. | salicornia herbacea l. (chenopodiaceae) has been used as a seasoned vegetable by living in coastal areas. s. herbacea (sh) has been demonstrated to stimulate cytokine production, nitric oxide release, and to show anti-oxidative effect. in a series of investigations to develop potential anti-diabetic and/or anti-hyperlipidemic agents from korean indigenous plants, 50% ethanol extract of salicornia herbacea was found to prevent the onset of the hyperglycemia and hyperlipidemia induced by high fat ... | 2006 | 16597000 |
| macrophage activation by polysaccharide fraction isolated from salicornia herbacea. | we demonstrate that polysaccharides isolated from salicornia herbacea (salicornia polysaccharides, sps) significantly induces nitric oxide (no) production and inducible no synthase (inos) transcription through the activation of nuclear factor-kappab/rel (nf-kappab/rel). sps dose-dependently induced the production of no in isolated mouse peritoneal macrophages and raw 264.7, a mouse macrophage-like cell line. moreover, inos gene expression was strongly induced by sps in raw 264.7 cells. to furthe ... | 2006 | 16183225 |
| inhibitory effects of isorhamnetin-3-o-beta-d-glucoside from salicornia herbacea on rat lens aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. | the inhibitory effects of compounds from salicornia herbacea (chenopodiaceae) on rat lens aldose reductase (rlar) and sorbitol accumulation in streptozotocin-induced diabetic rat tissues were investigated. the various fractions from the meoh extract of s. herbacea were tested for their effects on rlar in vitro. among them, the etoac fraction was found to exhibit a potent rlar inhibition (ic(50)=0.75 microg/ml), from which an active principle as a potent ar inhibitor was isolated and its chemical ... | 2005 | 15863906 |
| hypolipidemic effect of salicornia herbacea in animal model of type 2 diabetes mellitus. | to control blood glucose level as close to normal is a major goal of treatment of diabetes mellitus. hyperglycemia and hyperlipidemia are the major risk factors for cardiovascular complications, the major cause of immature death among the patients with type 2 diabetes. the purpose of this study is to determine the hypoglycemic and hypolipidemic effects of salicornia herbacea in animal model of type 2 diabetes and to investigate the possible mechanisms for the beneficial effects of s. herbacea. s ... | 2007 | 20368964 |
| anti-proliferative effect of polysaccharides from salicornia herbacea on induction of g2/m arrest and apoptosis in human colon cancer cells. | in this study, we investigated the anti-proliferative effect of polysaccharides from salicornia herbacea on ht-29 human colon cancer cells. crude polysaccharides from s. herbacea (cs) were prepared by extraction with hot steam water, and fine polysaccharides from s. herbacea (ps) were obtained through further size exclusion chromatography. the anti-proliferative effect of cs and ps were measured using the mts assay, apoptosis analysis, cell cycle analysis, and rt-pcr. ht-29 cells were treated wi ... | 2009 | 19996705 |