| fulminating fungal sinusitis caused by valsa sordida, a plant pathogen, in a patient immunocompromised by acute myeloid leukemia. | we describe a case in which a patient immunocompromised by acute myeloid leukemia experienced acute fulminating invasive fungal sinusitis followed by pneumonia and then death. though the microbiology of the pneumonia could not be directly investigated, nasal lesions revealed fungal mycelium. valsa sordida was consistently cultured from a biopsied sample. the fungus was identified to the genus level based on morphology in culture and dna sequence homology, and then was placed at species level by ... | 2006 | 16966170 |
| [investigation of the effect of constructions in hospital environment on the crucial units for immunocompromised patients and the development of opportunistic mold infections]. | this study was planned to determine the effect of building constructions in and around our hospital, on the development of opportunistic mold infections in immunocompromised patients hospitalized in bone marrow and kidney transplantation units and haematology and oncology units. samples were collected from high risk units by an air sampler (air ideal) from indoors and outdoors of a total of 43 patient rooms. the most commonly isolated species from indoor air cultures of our hospital were penicil ... | 2008 | 18444565 |
| cloning and characterization of a novel chitinase gene (chi46) from chaetomium globosum and identification of its biological activity. | chitinases play a major role in the defensive strategies of plants against fungal pathogens. in the current study, the gene for a 46-kda endochitinase (chi46) was cloned from chaetomium globosum, an important biocontrol fungus. the corresponding complementary deoxyribonucleic acid sequence was 1,350 bp in length, encoding 449 amino acid residues. the temporal expression of chi46, in response to the treatments of cell walls of six pathogens and confrontation against two fungal pathogens, was meas ... | 2008 | 18563407 |
| cloning and characterization of a chitinase gene lbchi31 from limonium bicolor and identification of its biological activity. | chitinases are digestive enzymes that break down glycosidic bonds in chitin. in the current study, an endochitinase gene lbchi31 was cloned from limonium bicolor. the cdna sequence of lbchi31 was 1,107 bp in length, encoding 322 amino acid residues with a calculated molecular mass of 31.7 kda. clustal analysis showed that there was a highly conserved chitin-binding domains in lbchi31 protein, containing four sulfide bridges. the lbchi31 gene was inserted into the ppic9 vector and transferred int ... | 2010 | 19685157 |
| cloning, heterologous expression, and functional characterization of a chitinase gene, lbchi32, from limonium bicolor. | in the present study, an endochitinase gene, lbchi32, was cloned from limonium bicolor. the cdna sequence of lbchi32 was 1,443 bp in length and encoded 319 amino acid residues. the dna sequence of lbchi32 was 2,512 bp in length and contained three exons and two introns. the lbchi32 gene was inserted into a ppic9 vector and transferred into pichia pastoris strains gs115 and km71 for heterologous expression. sds-page analyses indicated that lbchi32 was expressed in both gs115 and km71 and that it ... | 2010 | 20512617 |