| erve virus, a probable member of bunyaviridae family isolated from shrews (crocidura russula) in france. | an apparently new agent, provisionally named erve virus, was isolated in 1982 from tissues of three white toothed shrews, crocidura russula, trapped near saulges village in western france. results of virological and ultrastructural studies suggest that this virus belongs to the bunyaviridae family and is a bunyavirus-like agent. serosurveys indicate that erve virus had apparently a large geographical distribution in france and infects rodents, insectivores, wild boars (sus scrofa), red deer (cer ... | 1989 | 2570514 |
| thunderclap headache caused by erve virus? | systematic studies of a possible human neuropathogenicity of the erve virus have not yet been carried out. in a randomized, blind study 166 patients with viral encephalitis, 46 patients with cerebral hemorrhage, 72 patients with "thunderclap" headache, and 205 healthy blood donors were examined by indirect immunofluorescence for erve virus antibodies. none of the patients with encephalitis, two patients with cerebral hemorrhage (4.3%), 10 patients with thunderclap headache (13.9%; p < 0.0001), a ... | 1998 | 9484383 |
| [erve and eyach: two viruses isolated in france, neuropathogenic for man and widely distributed in western europe]. | two arboviruses have been isolated from mayenne, western france, in 1981-1982, during systematic field surveys: eyach virus, a cultivirus from ixodes ricinus and i. ventalloi ticks, and erve virus, a nairovirus from the tissues of white-toothed shrews, crocidura russula. for many years, these two viruses were considered as "orphan viruses" without pathogenic power for man, since it became evident that they circulate actively in europe among populations of wild small and large mammals. moreover, ... | 1998 | 9673063 |
| the erve virus: possible mode of transmission and reservoir. | the erve virus is suspected to cause severe headache in humans, lasting several days (thunderclap headache). mice are characterized as a probable reservoir for the erve virus. we tested 396 wild mice for erve virus using an immunofluorescence test and found erve virus antibodies in five cases, showing that small mammals form a reservoir for erve virus. if ticks are the vector for the virus, a coincidence with borreliosis should exist. we were unable to confirm this in a homogeneous cohort of 955 ... | 2000 | 10879642 |
| genetic characterization of erve virus, a european nairovirus distantly related to crimean-congo hemorrhagic fever virus. | erve virus (ervev) is a european nairovirus that is suspected to cause severe headache (thunderclap headache) and intracerebral hemorrhage. the mode of transmission to humans (ticks or mosquitoes) is still unknown. currently, no standardized testing method for ervev exists and only a small partial sequence of the polymerase gene is available. here, we present the first complete genome sequence of ervev s, m, and l segments. phylogenetic comparison of the amino acid sequence of the l-protein (rna ... | 2012 | 22864548 |
| genomic characterization of the genus nairovirus (family bunyaviridae). | nairovirus, one of five bunyaviral genera, includes seven species. genomic sequence information is limited for members of the dera ghazi khan, hughes, qalyub, sakhalin, and thiafora nairovirus species. we used next-generation sequencing and historical virus-culture samples to determine 14 complete and nine coding-complete nairoviral genome sequences to further characterize these species. previously unsequenced viruses include abu mina, clo mor, great saltee, hughes, raza, sakhalin, soldado, and ... | 2016 | 27294949 |
| genomic characterization of yogue, kasokero, issyk-kul, keterah, gossas, and thiafora viruses: nairoviruses naturally infecting bats, shrews, and ticks. | the genus nairovirus of arthropod-borne bunyaviruses includes the important emerging human pathogen, crimean-congo hemorrhagic fever virus (cchfv), as well as nairobi sheep disease virus and many other poorly described viruses isolated from mammals, birds, and ticks. here, we report genome sequence analysis of six nairoviruses: thiafora virus (tfav) that was isolated from a shrew in senegal; yogue (yogv), kasokero (kkov), and gossas (gosv) viruses isolated from bats in senegal and uganda; issyk- ... | 2015 | 26324724 |
| biochemical and structural insights into the preference of nairoviral deisgylases for interferon-stimulated gene product 15 originating from certain species. | the regulation of the interferon type i (ifn-i) response has been shown to rely on posttranslational modification by ubiquitin (ub) and ub-like interferon-stimulated gene product 15 (isg15) to stabilize, or activate, a variety of ifn-i signaling and downstream effector proteins. unlike ub, which is almost perfectly conserved among eukaryotes, isg15 is highly divergent, even among mammals. since zoonotic viruses rely on viral proteins to recognize, or cleave, isg15 conjugates in order to evade, o ... | 2016 | 27412597 |
| structural and functional diversity of nairovirus-encoded nucleoproteins. | the nairoviruses include assorted tick-borne bunyaviruses that are emerging as causative agents of infectious diseases among humans and animals. as negative-sense single-stranded rna (-ssrna) viruses, nairoviruses encode nucleoprotein (np) that encapsidates the genomic rna and further forms ribonucleoprotein (rnp) complex with viral rna-dependent rna polymerase (rdrp). we previously revealed that the monomeric np encoded by crimean-congo hemorrhagic fever virus (cchfv) presents a racket-shaped s ... | 2015 | 26246561 |