Publications

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pcb residues in mullet, mugil cephalus, fed to captive eastern australian water rats, hydromys chrysogaster. 1978104751
pesticide contamination of water rats in the murrumbidgee irrigation areas, new south wales, australia, 1970-72.organochlorine pesticides were found in all samples of livers, kidneys, mammary glands, and fetuses of eastern water rats (hydromys chrysogaster) collected in the murrumbidgee irrigation areas of new south wales in 1970 and 1972. dde was the predominant residue. livers contained 0.01--3.10 ppm sigma ddt air-dried weight; kidneys, less than 0.01--1.12 ppm; mammary glands, 0.14--23.75 ppm; fetal liver, 0.28--0.66 ppm. variations in residue levels are discussed in relation to the possible effects o ...1979461114
experimental infections of brush-tailed possums, common wombats and water rats with leptospira interrogans serovars balcanica and hardjo.of 12 brush-tailed possums (trichosurus vulpecula) inoculated with leptospira interrogans serovar balcanica 11 developed migroagglutination (ma) antibody to jardjo antigen by 14 days postincubation (pi). leptospiruria was observed in 2 possums 117 to 145 days pi. of 6 possums inoculated with serovar hardjo 4 developed low short-lived titres by day 18 pi. two of 3 wombats (vombatus ursinus) inoculated with balcanica had high ma titres (greater than or equal to 1:128) by day 16 pi and leptospiruri ...1979533478
rodent zoonoses in north queensland: the occurrence and distribution of zoonotic infections in north queensland rodents.a study of potentially zoonotic infections was carried out on 351 rodents trapped in north-eastern queensland. their ecosystems included towns, agricultural and livestock areas, wookland and rainforest. nine serotypes of salmonellae were obtained from asymptomatic carries in predominantly settled locations. two strains of ps. pseudomallei occurred in rainforest near innisfail and one on a cattle property adjacent to townsville. ps. aeruginosa caused bronchopneumonia in one animal from townsville ...1978678225
changes in brain regional manganese and magnesium levels during postnatal development: modulations by chronic manganese administration.manganese (mn) and magnesium (mg) levels in hypothalamus, cerebellum, pons and medulla, striatum, midbrain, and cerebral cortex of control and mn-treated (10 mg mncl2.4h2o per ml of drinking water) rats during postnatal development were studied using instrumental neutron activation analysis. the age-dependent mn accumulation showed regional variation: at day 5, this accumulation was most marked in striatum (12.05 micrograms/g wet weight) but least marked in cerebral cortex (0.85 micrograms/g wet ...19921608364
regional alterations in hexokinase activity within rat brain during dehydration and rehydration.histochemical localization and photodensitometric quantification of the metabolic enzyme, hexokinase (hk), were used to study changes in brain metabolic activity that occur during the development of (5 days) and recovery from (7 days) dehydration. in water-deprived (wd) rats, hk activity increased after 2 days in the subfornical organ (sfo, 22%), nucleus circularis (nc, 36%), parvo- and magnocellular divisions of the paraventricular nucleus (ppvh, 17%; mpvh, 46%) and supraoptic nucleus (son, 46% ...19892719147
intimal changes in the aorta of prehypertensive rats.intimal changes were quantitated in several rat models of arterial hypertension. one kidney-one clip rats drinking water (1k-1c-water), one-kidney rats treated with deoxycorticosterone acetate and drinking 1% nacl (1k-doca-salt), and two-kidney rats drinking 1% nacl (2k-salt) were studied after 1 to 8 weeks. the thoracic aorta was examined en face and by electron microscopy. surprisingly, all 2k-salt, most 1k-doca-salt (17 out of 19), and two-thirds of 1k-1c-water rats (12 out of 18) had normal ...19883169204
basic carriers of trichophyton mentagrophytes var. gypseum in the sverdlovsk region.tests for myococarriers were made on 4.297 wild small mammals. clinical examinations only were carried out on 1,204 animals, both clinical and laboratory examinations on 3,093 animals. the suppurative form of trichophytosis was diagnosed in only one specimen of microtus oeconomus out of 1,204 animals examined. t. ectothrix microides was found in the hair taken from the focus. t. mentagrophytes var. gypseum was obtained by culture on nutrient media. no clinical signs of mycosis were found in 3,09 ...19873680938
energy requirement and coefficient of utilization of food in the common hamster and water rat. 19724668839
a rickettsia-like organism from a water-rat, hydromys chrysogaster, from brisbane. 19674864429
[studies of wild reservoirs and vectors of trypanosoma cruzi. xxvi. natural infection of the water rat, nectomys squamipes squamipes (brants, 1827) with t. cruzi]. 19684971320
klossiella hydromyos n. sp. from the kidneys of an australian water rat (hydromys chrysogaster). 19715006041
[detection of the tularemia zoonosis in the territory of the kartlian plain].the natural focus of tularemia was found to cover the whole territory of the kartlian plain. epizooty occurred mainly among common voles with the involvement of insectivorous voles. hard ticks, gamasids and fleas infected with francisella tularensis were detected. rodents highly sensitive to tularemia can be affected by this infection. water rats were not involved into the enzootic process. further studies are necessary for the final solution of this problem.19836225274
uncinaria hydromyidis sp, n (nematoda: ancylostomatidae) from the australian water rat, hydromys chrysogaster. 19807218097
the prevalence of anti-leptospiral agglutinins in sera of wildlife in southeastern australia.anti-leptospiral agglutinins were found in the serum from 18 (7 species) of 419 (25 species) animals sampled from various areas of southeastern australia. positive serologic reactions were observed in 5 of 25 (20%) brush-tailed possum (trichosurus vulpecula), 1 of 26 (3.8%) tammar wallaby (macropus eugenii), 2 of 12 (16.7%) swamp wallaby (wallabia bicolor), 1 of 3 (33.3%) koala (phascolarctos cinereus), 3 of 41 (7.3%) common wombat (vombatus ursinus), 2 of 100 (2%) bush rat (rattus fuscipes) and ...19817241704
leptospirosis in wildlife in brazil: isolation of serovars canicola, pyrogenes and grippotyphosa.the isolation of serovar canicola from the norway rat (rattus norvegicus), shows that it is a reservoir of canicola and is therefore significant from an epidemiological point of view. the isolation of pyrogenes and grippotyphosa from a water rat, nectomys squamipes is also described.19807461916
review of styrene and styrene oxide long-term animal studies.eleven long-term toxicity studies were reviewed on styrene and five on styrene oxide in an effort to evaluate the potential carcinogenic activity of these chemicals in animals. the styrene studies included inhalation exposure (rats, mice, guinea pigs, and rabbits), intragastric gavage (rats and mice), drinking water (rats), and intraperitoneal injection (rats), while styrene oxide exposure was via intragastric gavage (rats and mice) or skin painting (mice). each study was reviewed and evaluated ...19947818772
protozoan parasites and pathological findings in hydromys chrysogaster (muridae: hydromyinae) from queensland.tissues from 23 australian water rats (hydromys chrysogaster) collected from five localities in central and northern queensland, australia, between february 1992 and may 1993, were examined for protozoan parasites and additional pathological changes. we found klossiella hydromyos in the kidneys, toxoplasma gondii in the brain and skeletal muscles and sarcocystis sp. in the somatic musculature. other pathological findings, including interstitial nephritis, interstitial pneumonia and a tongue absc ...19968722276
tapironema coronatum n. gen., n. sp. (trichostrongyloidea-cooperiidae-obeliscoidinae), a parasite of holochilus brasiliensis and tapirus terrestris.in this paper we provide a description of tapironema coronatum n. gen. n. sp. (trichostrongyloidea, obeliscoidinae) from the cricetid holochilus brasiliensis or "water rat" in argentina (type material) and from tapirus terrestris in french guyana (voucher material in poor condition). the new genus is characterized by a corona radiata, an oesophageal tooth, a bilaterally synlophe with about 73 (male), 122 (female) cuticular ridges, a caudal bursa pattern 2-1-2 with rays 5 and 6 parallel and close ...19979587607
reevaluation of physaloptera bispiculata (nematoda: spiruroidaea) by light and scanning electron microscopy.this study was undertaken to clarify several aspects of morphological and taxonomic characters of physaloptera bispiculata vaz and pereira, 1935, a parasite of the water rat, nectomys squamipes. the cephalic structures (including lips, papillae, teeth, amphids, and porous areas) and details of the posterior end of male and female adult worms were examined by scanning electron microscopy, leading to the addition of new taxonomic characters for this species. we consider p. bispiculata a valid spec ...19989645861
susceptibility of nectomys rattus (pelzen, 1883) to experimental infection with schistosoma mansoni (sambon, 1907): a potential reservoir in brazil.the aim of the present research was to evaluate the potential of nectomys rattus, the "water rat", to develop schistosoma mansoni infection. comparison with n. squamipes was carried out. both species of rodents were submitted to transcutaneous infection using different infective cercariae loads: 50, 100 or 500. n. rattus showed high susceptibility to s. mansoni, with an infection rate of 71%. rodents were able to excrete viable eggs of s. mansoni in the faeces during all infection period. for bo ...19989921374
a new nematode, ansiruptodera scapteromi sp.nov. (nematoda: aspidoderidae), recovered from the argentinean water rat scapteromys tumidis (waterhouse, 1837) in uruguay.this report describes a new species of aspidoderid nematode, ansiruptodera scapteromi sp. nov., the second species to be reported in the genus ansiruptodera skrjabin and shikhobalova, 1947. the a. scapteromi sp. nov. is the first species of the genus to be recorded from a rodent host. the new species is clearly different from the only other species, a. ansiruipta (proença, 1937) skrjabin and shikhobalova, 1947, in that it possesses short lateral alae that terminate before the midbody; a smaller ...199910382611
structure and innervation of the vibrissal follicle-sinus complex in the australian water rat, hydromys chrysogaster.light and electron microscopic techniques were used to examine the structure and innervation of the mystacial vibrissal follicle-sinus complex (f-sc) in the australian water rat. the f-scs of this semiaquatic rodent show the same morphologic elements described in terrestrial rats but differ in size, structure, and innervation. most striking is the size of the water rat's caudal f-scs, measuring 6.3 mm in length and 2.4 mm in diameter. the sinus system is divisible into a ring sinus and a caverno ...199910421867
identification of microsatellite loci in the water-rat nectomys squamipes (rodentia, sigmodontinae). 200011123638
robertsonian polymorphism, b chromosomes variation and sex chromosomes heteromorphism in the african water rat dasymys (rodentia, muridae).chromosome banding analysis (g- and c-bands) of dasymys rufulus from senegal, mali and the ivory coast, and d. cf. incomtus from eastern and south-western ethiopia was carried out. the diploid numbers (2n) in the former species range between 36 and 39 due to the presence of 0-3 small biarmed heterochromatic b chromosomes, resulting in a corresponding variation of the number of autosomal arms (nfa) between 44 and 50. the basic autosomal set was, however, constant and identical in these specimens. ...200011196132
fecundity of hoplopleura scapteromydis (phthiraptera: anoplura, hoplopleuridae), ectoparasite of scapteromys aquaticus (rodentia: muridae) in rio de la plata marshlands, argentina.density and age structure of lice collected from captured scapteromys aquaticus rodents were studied to estimate the fecundity of hoplopleura scapteromydis. the number of eggs with a visible embryo inside (e), nymphs (n), adult males (am), and adult females (af) were recorded for each rodent. for the ith rodent, the fecundity of h. scapteromydis, f(i), was estimated as f(i) = [[e(i) + n(i)]/2]/af(i)/t, where t represents the period of preimaginal development (unknown and arbitrarily considered a ...200111426716
biological aspects of a new isolate of echinostoma paraensei (trematoda: echinostomatidae): susceptibility of sympatric snails and the natural vertebrate host.a new isolate of echinostoma paraensei (lie & basch, 1967) was obtained from a natural vertebrate host, the water rat nectomys squamipes. relationships with sympatric snails, biomphalaria glabrata; physa marmorata and lymnaea columella, as well as allopatric snails and the definitive hosts n. squamipes, mus musculus, rattus norvegicus, mesocricetus auratus and birds were investigated. e. paraensei developed in all sympatric snail species following exposure to one or five miracidia. p. marmorata ...200111688893
new records and laboratory-rearing data for ixodes schulzei (acari: ixodidae) in brazil.ixodes schulzei aragão and fonseca was described from brazil in 1951 based on female ticks collected on wild rats from the states of rio de janeiro and santa catarina. since that time, there have been no additional reports of i. schulzei in the literature. we report two new records of i. schulzei: a female collected on the water rat nectomys squamipes (brants) from minas gerais state, and another female from this same host species from são paulo state. this last specimen was engorged and oviposi ...200312597665
cuticular architecture of hassalstrongylus epsilon (nematoda: trichostrongyloidea).hassalstrongylus epsilon is a small nematode, whose adult forms are found among the intestinal microvilli of the water rat nectomys squamipes, brants 1827 (rodentia: muridae). the external appearance of the cuticle, which presents transversal striations and longitudinal ridges, is described using scanning electron microscopy. transmission electron microscopy of thin sections and replicas of quick-frozen, freeze-fractured, deep-etched and rotatory shadowed samples showed the presence in the cutic ...200312884020
arthropod and filarioid parasites associated with wild rodents in the northeast marshes of buenos aires, argentina.during 1995, 16 species of arthropods and 2 species of filarioids, totaling 1 287 specimens were collected from 64 wild rodents captured in the hudson natural reserve, buenos aires, argentina. infestation parameters and indexes were analyzed. host specific richness was s = 6, diversity h = 1.48, and relative density rdi = 40%. high values of parasite species richness and diversity were found on oligoryzomys delticola (s = 9; h = 1.40), oxymycterus rufus (s = 9; h = 1.37), and oligoryzomys flaves ...200312973536
[hygienic evaluation of water rat control methods using arsenicals]. 196314187243
a virus of the encephalomyocarditis group from a water-rat, hydromys chrysogaster, in north queensland. 195914434075
inheritance of white head spotting in natural populations of south american water rat (nectomys squamipes rodentia: sigmodontinae).specimens with white head spots are present at low frequency in the natural populations of south american water rat (nectomys squamipes) and absent in the sibling species nectomys rattus. we analyzed the pattern of inheritance of the phenotype using complex segregation analysis of pedigrees of a captive-bred population of n. squamipes. we found that the inheritance of the white head spot in this species can be described within the framework of the major gene recessive model with incomplete penet ...200414757733
wild and synanthropic hosts of leishmania (viannia) braziliensis in the endemic cutaneous leishmaniasis locality of amaraji, pernambuco state, brazil.evidence of leishmania infection was found in small mammals captured between 1996 and 2000 in the amaraji region, pernambuco state, brazil. the kdna polymerase chain reaction (pcr), using primers specific for subgenus l. (viannia), was positive for 43/153 water rats (nectomys squamipes), 13/81 black rats (rattus rattus), 15/103 grass mice (bolomys lasiurus), 1/14 marsh mice (holochilus scieurus), 2/50 field mice (akodon arviculoides), 2/12 woolly opossums (marmosa sp.), and 5/37 common opossums ...200315228244
prolonged and transient neonatal hypothyroidism on leydig cell differentiation in the postnatal rat testis.hypothyroidism arrests the differentiation of adult leydig cells (alc) in the neonatal rat testis, and transient neonatal hypothyroidism produces a two-fold increase in the alc numbers in the adult rat testis. we investigated 1) whether prolonged hypothyroidism beyond the neonatal period could continue to arrest the differentiation of the alc, and 2) to understand how a two-fold increase in the number of alc is produced in adult rats subjected to transient neonatal hypothyroidism. three groups o ...200415551749
experimental evidence and ecological perspectives for the adaptation of schistosoma mansoni sambon, 1907 (digenea: schistosomatidae) to a wild host, the water-rat, nectomys squamipes brants, 1827 (rodentia: sigmodontinae).due to the semi aquatic habits and the overlap of the geographical distribution of the water-rat, nectomys spp., with schistosomiasis endemic areas, these wild rodents are very likely to acquire schistosoma mansoni infection in their daily activities. the role of the water-rat in the s. mansoni cycle would be substantiated if one could prove that these rodents acquire the parasite during their own activity time, a completely independent time schedule of human activities. to pursue this goal, we ...200212426586
the primordial cranium of microtus amphibius (water-rat), as determined by sections and a model of the 25-mm. stage. with comparative remarks. 191717103821
helminth communities of nectomys squamipes naturally infected by the exotic trematode schistosoma mansoni in southeastern brazil.the water rat nectomys squamipes is endemic in brazil and found naturally infected with schistosoma mansoni. helminth communities, their prevalences, intensity of infection and abundance in n. squamipes in an endemic area of schistosomiasis in the state of rio de janeiro, brazil were studied. four species of nematodes (physaloptera bispiculata, syphacia venteli, hassalstrongylus epsilon and litomosoides chagasfilhoi) were recovered in 85.3%, two trematodes (schistosoma mansoni and echinostoma pa ...200617125546
redescription of trichuris laevitestis (nematoda: trichuridae) from akodon azarae and scapteromys aquaticus (sigmodontinae: cricetidae) in buenos aires province, argentina.trichuris spp. have a cosmopolitan distribution; the species are typically identified by features related to the reproductive system. trichuris laevitestis was described on the basis of specimens collected from rodents captured in punta lara, buenos aires province, argentina. here, t. laevitestis is redescribed considering new and relevant morphological features of diagnostic importance such as arrangement of spines on the spicular sheath, spicule length, length and shape of proximal cloacal tub ...200617152950
the systematic position of some nippostrongyline nematodes (trichostrongylina: heligmosomoidea) parasitic in argentinean sigmodontine rodents.the systematic position of two nippostrongyline nematodes described from argentinean sigmodontine rodents is clarified. the first species, hassalstrongylus multiovatus suriano & navone, 1992, parasitic in akodon simulator thomas from the province of tucumán, was studied on the basis of type and voucher material. h. multiovatus is proposed as a junior synonym of trichofreitasia lenti sutton & durette-desset, 1991, a parasite described from oligoryzomys flavescens (waterhouse) in the province of b ...200717195037
changes on schistosoma mansoni (digenea: schistosomatidae) worm load in nectomys squamipes (rodentia: sigmodontinae) concurrently infected with echinostoma paraensei (digenea: echinostomatidae).the water rat, nectomys squamipes, closely involved in schistosomiasis transmission in brazil, has been found naturally infected simultaneously by schistosoma mansoni and echinostoma paraensei. laboratory experiments were conducted to verify parasitic interaction in concurrent infection. it was replicated four times with a total of 42 water rats and essayed two times with 90 mice pre-infected with e. paraensei. rodents were divided into three groups in each replication. a wild strain recently is ...200111586449
influence of phenobarbital on changes in na(+) handling, hemodynamics and liver function due to partial portal vein ligation in rats.this study examined the influence of phenobarbital, an inducer of hepatic enzymes, on na(+) handling, hemodynamics and liver function (measured by the rate constant of elimination of aminopyrine in the aminopyrine breath test) after partial portal vein ligation. rats were randomized to drink either phenobarbital + water or water only for 10 days and then underwent either sham operation or partial portal vein ligation. the aminopyrine rate constant of elimination and na(+) balance were measured d ...200111226405
the parasitism of schistosoma mansoni (digenea-trematoda) in a naturally infected population of water rats, nectomys squamipes (rodentia-sigmodontinae) in brazil.schistosomiasis is a health problem in brazil and the role of rodents in maintaining the schistosome life-cycle requires further clarification. the influence of schistosoma mansoni on a population of nectomys squamipes was studied by capture-recapture (1st phase, from june 1991 to november 1995) and removal (2nd phase, from april 1997 to march 1999) studies at sumidouro, rio de janeiro, brazil. during both phases coproscopic examinations were performed. at the 2nd phase the rodents were perfused ...200010874720
energetics of locomotion by the australian water rat (hydromys chrysogaster): a comparison of swimming and running in a semi-aquatic mammal.semi-aquatic mammals occupy a precarious evolutionary position, having to function in both aquatic and terrestrial environments without specializing in locomotor performance in either environment. to examine possible energetic constraints on semi-aquatic mammals, we compared rates of oxygen consumption for the australian water rat (hydromys chrysogaster) using different locomotor behaviors: swimming and running. aquatic locomotion was investigated as animals swam in a water flume at several spee ...19999914144
heterogeneity and meiotic behaviour of b and sex chromosomes, banding patterns and localization of (ttaggg)n sequences by fluorescence in situ hybridization in the neotropical water rat nectomys (rodentia, cricetidae).a cytogenetic study using fluorescence in situ hybridization (fish) of telomere probes, cbg, gtg and rbg banding patterns and synaptonemal complex data was carried out in 41 specimens of nectomys from three brazilian states: pernambuco, mato grosso and são paulo. the specimens presented 2n = 52, 53, 56 and 57, and the differences in chromosome number were due to the presence of three different supernumeraries and also to the occurrence of tandem fusions. the tandem fusions involved chromosome pa ...19989865784
the relationship of sex and ectoparasite infestation in the water rat scapteromys aquaticus (rodentia: cricetidae) in la plata, argentina.i studied the relationship between sex and infestation with ectoparasites in the water rat scapteromys aquaticus from la plata river marshland, argentina. the relative density's index (rdi) for males was 3.90% (females 3.60%). a total of 2653 ectoparasites were collected on 33 male hosts, and 1945 on 31 females. ectoparasite specific richness (s) and diversity (h) were s = 14, h = 1.17 on males, and s = 10, h = 1.52 on females. the similarity between male and female rodents according to their ec ...200618494333
there be land rats and water rats. 191718737324
lifetime health risk assessment from exposure of recreational users to polycyclic aromatic hydrocarbons.in order to assess the lifetime risk of skin cancer for recreational users from dermal exposure to polycyclic aromatic hydrocarbons (pahs), sediment samples were collected from beach sites along the st. marys river near sault ste. marie, ontario, and in hamilton harbor and toronto harbor, ontario, and analyzed for pahs. dermal exposure and lifetime skin cancer risk were estimated as follows: concentrations of 11 pahs with sufficient or limited evidence of carcinogenicity or mutagenicity were con ...19989732487
australian helminths in australian rodents: an issue of biodiversity.the australian public as well as australian funding bodies are generally unsympathetic to native murids, rats and mice, in spite of the fact that 36% have either become extinct or critically endangered since european settlement. the endemic australian parasites of these rats and mice have been even less sympathetically regarded. prior to 1958 very little work was carried out on the helminths of australian rodents and little more is known today. records are known from only 28% of the extant host ...19989673864
serological studies in nectomys squamipes demonstrate the low sensitivity of coprological exams for the diagnosis of schistosomiasis.the existence of wild rodents naturally infected by schistosoma mansoni is a drawback for schistosomiasis control programs. as a consequence, it is necessary to have a precise diagnosis of s. mansoni infection in wild rodents (water rats; nectomys squamipes), the species seemingly involved in the transmission of schistosomiasis at sumindouro, rio de janeiro, brazil. a total of 78 specimens of n. squamipes was captured in an endemic area at vale do pamparrão and porteira verde, sumidouro, brazil; ...200918983203
effects of subchronic exposure of monochloramine in drinking water on male rats.a subchronic rat study with paired-water control was conducted to resolve the question of whether monochloramine at 200 ppm in drinking water can cause reduced body weight gain and other changes observed in earlier investigations. male sprague-dawley rats (93 +/- 5 g) were divided into three groups of 10 rats each: the treatment group was fed drinking water containing 200 ppm monochloramine, the control group was fed bicarbonate-buffered water ad libitum, and the paired-water control rats were g ...19979185892
twenty-four hours, or five days, of continuous sleep deprivation or experimental sleep fragmentation do not alter thirst or motivation for water reward in rats.sleep disruption results in an increased demand for energy, which typically causes hyperphagia in an attempt to redress the energy metabolism imbalance. therefore, experiments combining food reward and sleep disruption may underestimate the effect of sleep disruption due to their contradictory influences on behavior (for example on operant measures of attention). in contrast, water is not a central component of energy metabolism and thus thirst may not be affected by sleep disruption. however, l ...201020493906
determinants of ectoparasite assemblage structure on rodent hosts from south american marshlands: the effect of host species, locality and season.the relative effects of host species identity, locality and season on ectoparasite assemblages (relative abundances and species richness) harboured by four cricetid rodent hosts (akodon azarae, oligoryzomys flavescens, oxymycterus rufus and scapteromys aquaticus) were assessed across six closely located sites in buenos aires province, argentina. relative abundances of ectoparasites (14 species including gamasid mites, an ixodid tick, a trombiculid mite, lice and fleas), as well as total ectopara ...201020546127
the first description of eggs in the male reproductive system of physaloptera bispiculata (nematoda: spiruroidaea).physaloptera bispiculata (nematoda: spiruroidaea) is a parasite of nectomys squamipes (rodentia: cricetidae), a water rat that only occurs in brazil. naturally infected rodents were captured in the municipality of rio bonito, rio de janeiro, brazil. adult p. bispiculata worms were collected, prepared and analysed by light and scanning electron microscopy. under scanning electron microscopy, several eggs were seen glued by cement to the cloacal aperture. light microscopy revealed that some male w ...201020653989
breeding of the water rat (nectomys squamipes) in the laboratory.the water rat, nectomys squamipes, is reported as a natural host of schistosoma mansoni in brazil. this paper presents some reproductive, growth and developmental data, and laboratory management of a breeding programme for n. squamipes. the colony was derived from animals captured at sumidouro, rio de janeiro state. the animals' diploid number was 56, conception rate was 66.7% and gestation period was 30 days. litter size ranged from 1 to 6, with a mean of 4.1 (sd +/- 1.2) and a mode of 4 and 5. ...19968938625
toxicology studies of a chemical mixture of 25 groundwater contaminants: hepatic and renal assessment, response to carbon tetrachloride challenge, and influence of treatment-induced water restriction.because groundwater contamination is an important environmental concern, we examined the hepatic and renal effects of repeated exposure to a mixture of 25 chemicals frequently found in groundwater near hazardous-waste disposal sites and the effect of such exposure on carbon tetrachloride (cci4) toxicity. adult male f-344 rats received ad libitum deionized water and feed (ad lib water) or ad libitum 10% mix (referring to 10% of a technically achievable stock mixture) and feed for 14 d. because ex ...19947966440
seasonal dynamics and hosts of amblyomma triste (acari: ixodidae) in argentina.the seasonal dynamics and host usage of amblyomma triste in argentina were analyzed. adults of a. triste were present from early winter to mid-summer, with the peak of abundance from late winter to mid-spring (august to october). larvae and nymphs were found from december to june, with the peak of abundance in summer. there were no differences among the biological parameters (pre-moult period of larvae and nymphs, pre-oviposition period of females, and minimum incubation period of eggs) of engor ...201121536384
aliskiren reduces vascular pathology in diabetic retinopathy and oxygen-induced retinopathy in the transgenic (mren-2)27 rat.aim/hypothesis: we examined whether the renin inhibitor, aliskiren, provides similar or greater protection than ace inhibition from non-proliferative diabetic retinopathy and from the proliferative neoangiogenesis of oxygen-induced retinopathy. methods: transgenic (mren-2)27 rats, which overexpress mouse renin and angiotensin in extra-renal tissues, were studied. for diabetic studies, non-diabetic, diabetic (streptozotocin, 55 mg/kg), diabetic + aliskiren (10 mg kg(-1) day(-1), pump), or diabeti ...201121755314
Life-cycle and host preference of Amblyomma ovale (Acari: Ixodidae) under laboratory conditions.This study evaluated for the first time the life cycle of Amblyomma ovale in the laboratory. For this purpose, larvae and nymphs were exposed to Gallus gallus (chickens), Cavia porcellus (guinea pigs), Rattus norvegicus (wistar rats), Oryctolagus cuniculus (domestic rabbits), Calomys callosus (vesper mouse), and Didelphis albiventris (white-eared opossum). Nymphs were also exposed to Nectomys squamipes (South American water rat). Adult ticks were fed on dogs. The life-cycle of A. ovale in labora ...201122113779
description of a new capillariinae (nematoda: trichuridae) from scapteromys aquaticus (cricetidae: sigmodontinae) from buenos aires, argentina.abstract a new species of genus capillaria is described on the basis of specimens recovered from the intestine of the swamp rat scapteromys aquaticus (cricetidae: sigmodontinae) from argentina. capillaria alainchabaudi n. sp. and a peculiar species from australian marsupials are the only 2 species of capillaria sensu stricto parasitic in mammals. a comparison with the australian species and with the 18 species of this genus described from other vertebrates from the western hemisphere is given. ...201222236218
introduction and persistence of tularemia in bulgaria.outbreaks of the zoonotic disease tularemia occurred in north-east bulgaria in the 1960s. then came 30 years of epidemiological silence until new outbreaks occurred in west bulgaria in the 1990s. to investigate how bacterial strains of francisella tularensis causing tularemia in wildlife and humans in the 1960s and the 1990s were related, we explored their genetic diversity.201627790972
outbreak with clonally related isolates of corynebacterium ulcerans in a group of water rats.the zoonotic bacterium corynebacterium ulcerans may be pathogenic both in humans and animals: toxigenic strains can cause diphtheria or diphtheria-like disease in humans via diphtheria toxin, while strains producing the dermonecrotic exotoxin phospholipase d may lead to caseous lymphadenitis primarily in wild animals. diphtheria toxin-positive corynebacterium ulcerans strains have been isolated mainly from cattle, dogs and cats.201525887321
rodentborne fungal pathogens in wetland agroecosystem.the past few decades have witnessed an overwhelming increase in the incidence of fungal infections, particularly in immunocompromised individuals. consequently, zoonotic diseases, especially through rodents constitute a prominent group among the emerging diseases. rodents are commensal to man and related health risks are common. water rats (rattus norvegicus) are typical to vembanadu-kol wetland agroecosystems, where they can act as a good carrier nexus for pathogens. the present study evaluates ...201224031825
small mammals as hosts of leishmania spp. in a highly endemic area for zoonotic leishmaniasis in north-eastern brazil.leishmania parasites cause leishmaniasis in humans and animals worldwide. these parasites are transmitted by phlebotomine sand flies, which become infected upon feeding on an infected mammalian host. we assessed the occurrence of leishmania infection in small mammals in an area of cutaneous and visceral leishmaniasis endemicity.201323868744
natural schistosoma mansoni infection in the wild reservoir nectomys squamipes leads to excessive lipid droplet accumulation in hepatocytes in the absence of liver functional impairment.schistosomiasis is a neglected tropical disease of a significant public health impact. the water rat nectomys squamipes is one of the most important non-human hosts in the schistosomiasis mansoni transmission in brazil, being considered a wild reservoir. cellular mechanisms that contribute to the physiological adaptation of this rodent to the schistosoma mansoni parasite are poorly understood. here we identified, for the first time, that a hepatic steatosis, a condition characterized by excessiv ...201627880808
pressure-diuresis-natriuresis response in hyperthyroid and hypothyroid rats.1. renal responses to changes in renal perfusion pressure were studied in anaesthetized hyperthyroid (thyroxine, 300 micrograms day-1 kg-1) and hypothyroid (methimazole, 0.03% via drinking water) rats to determine whether an abnormality in the pressure-diuresis-natriuresis phenomenon is involved in the resetting of kidney function in these disorders. 2. there were no significant differences between control and hypothyroid rats with respect to the relationships between renal perfusion pressure an ...19947955909
chronic nitric oxide synthase inhibition and carotid artery distensibility in renal hypertensive rats.the goal of the present study was to examine the viscoelastic properties of the carotid artery in genetically identical rats exposed to similar levels of blood pressure sustained by different mechanisms. eight-week old male wistar rats were examined 2 weeks after renal artery clipping (two-kidney, one clip [2k1c] goldblatt rats, n = 53) or sham operation (n = 49). one half of the 2k1c and sham rats received the nitric oxide synthase inhibitor ng-nitro-l-arginine methyl ester (l-name, 1.48 mmol/l ...19957543453
[the osmoregulating function of the kidney and activity of the loop of henle in water rats, gerbils and brattleboro rats].the concentration index u-p osm in dehydration was 7.9 in gerbil, 2.7 in water rats and 1.7 in the brattleboro homozygote rats. the sodium content in the kidney medullar substance of the animals under study correlated with the ability for creation of the high concentration gradient u-p osm. the sodium excretion for 100 ml of filtrate, in maximal suppression with furosemide of the cl- ions reabsorption in the large ascending parti of henle's loop, was practically the same in all the rodents under ...19836873378
noteworthy records of ixodes schulzei (acari: ixodidae) on rodents from the state of parana, southern brazil.ixodes schulzei aragão & fonseca is an endemic tick to brazil and has already been reported in the northern (state of rondonia), southeastern (states of minas gerais, rio de janeiro and sao paulo) and southern (state of santa catarina) regions, always found in association with the water rat nectomys squamipes (brandt). this communication records the first occurrence of this tick species in the state of parana, southern region of brazil, and it constitutes its first report on akodon montensis (th ...201324252964
[the water rat (arvicola terrestris l.) as a natural reservoir of pathogenic leptospira]. 195624544493
life-cycle of amblyomma oblongoguttatum (acari: ixodidae) under laboratory conditions.this study evaluated for the first time the life cycle of amblyomma oblongoguttatum in the laboratory. for this purpose, larvae and nymphs were exposed to gallus gallus (chicks), rattus norvegicus (wistar rat), calomys callosus (vesper mouse), oryctolagus cuniculus (domestic rabbit), cavia porcellus (guinea pig), and didelphis albiventris (white-eared opossum). nymphs were exposed to g. gallus, c. callosus, c. porcellus, o. cuniculus, r. norvegicus, and nectomys squamipes (water rat). adult tick ...201728493036
endogenous noradrenaline re-uptake blocking factor in rats with reduced renal mass hypertension.this study was carried out to elucidate the involvement of the peripheral sympathetic nervous system in the pathogenesis of reduced renal mass (rrm)-salt hypertension in rats. male wistar rats underwent subtotal nephrectomy (70-80% reduction in renal mass). on the 10th postoperative day, systolic blood pressure was higher in rrm-salt rats than in rrm-water rats. perfusion of isolated mesenteric vasculature from normotensive rats, with the deproteinized plasma from rrm-salt hypertensive rats indu ...19883241217
circadian variations in plasma corticosterone permit normal termination of adrenocorticotropin responses to stress.we previously reported that adrenalectomized rats given constant corticosterone via a sc pellet (b-pellet) hypersecrete acth in response to stress. although lacking a feedback signal, b-pellet rats do not secrete acth indefinitely after stress; plasma acth levels in these animals returned to those in sham-operated (sham) rats within 1-4 h after 2-min restraint. to distinguish between the requirement for circadian or stress-induced increases in corticosterone, we compared changes in acth and cort ...19882831028
cytogenetics and karyosystematics of south american oryzomyine rodents (cricetidae: sigmodontinae). iv. karyotypes of venezuelan, trinidadian, and argentinian water rats of the genus nectomys.bone marrow chromosomes were studied in south american water rats of the genus nectomys from venezuela, trinidad, and argentina. specimens of n. squamipes from western and southern venezuela showed a 2n = 52-53 karyotype, whereas a 2n = 56-57 karyotype was found in specimens from northeastern argentina. in both cases, odd karyotypes can be explained by the presence of a supernumerary chromosome. in contrast, water rats from northeastern venezuela and trinidad showed a strikingly reduced 2n = 16- ...19921733670
oral caffeine consumption by rats: the role of flavor history, concentration, concurrent food, and an adenosine agonist.some determinants of caffeine consumption by rats were examined using the two-bottle choice test. to describe the role of flavor history, groups of eight rats each received one of three fluids as their only source of fluid beginning at 29 days of age and continuing throughout the experiments. one group ("water") received tapwater, a second group ("caffeine") received 0.5 mg/ml caffeine in tapwater, and a third group ("quinine") received 0.01 mg/ml quinine in tapwater. two-bottle choice tests beg ...19921513846
altered secretion of corticosteroids and prolactin in adrenal regeneration hypertensive rats.to assess the possible role of mineralocorticoids in the onset and maintenance of hypertension in adrenal regeneration hypertensive (arh) rats, the change in plasma mineralocorticoids, with adrenal regeneration after enucleation in arh rats was investigated and compared with those in unilaterally nephroadrenalectomized, 1% saline-fed (una) rats, sham-operated, 1% saline-fed (1% nacl) rats and water-fed (water) rats. plasma aldosterone was determined by ria and the other mineralocorticoids were m ...19921396350
behavioural change in rats due to chronic oral and systemic formaldehyde.impact of chronic formaldehyde exposure in respect of route on behaviour was studied. preconditioned (environmental) male albino rats (340-400 g) in 3 groups (n = 5) under 60 days oral and systemic exposure to 10 mg/kg/day hcho were examined for their behavioural performance (i.e. short term memory) in cook's apparatus. twenty percent rats settled in grade iii (unconditioned avoidance response) in the i.p. (i.e. systemic group) whereas in oral fed (hcho route in drinking water) rats, 60% settled ...19921291481
a serological survey of australian wildlife for antibodies to leptospires of the hebdomadis serogroup.a serological survey for antibodies to leptospira interrograns serovar hardjo was conducted on 574 serum samples from 10 native and 4 introduced wildlife species in south-eastern australia. the microscopic agglutination (ma) test was used, and titres to hardjo antigen were detected in 33.5% of 352 brushtailed possums (trichosurus vulpecula) sampled in several areas of victoria. prevalence of reactors ranged from 14 to 66% in 4 populations examined intensively. serovar balcanica was isolated from ...1979485984
deoxycorticosterone acetate-salt rats: hypertension and sympathoexcitation driven by increased nacl levels.using deoxycorticosterone acetate (doca)-salt rats, we tested the hypothesis that increased plasma nacl concentration supports sympathetic activity and blood pressure (bp) during salt-sensitive hypertension. one day before experimentation, femoral catheters and an electrode for measurement of lumbar sympathetic nerve activity (lsna) probe were surgically positioned in doca-salt and sham-salt rats. doca-salt rats exhibited increased (p<0.05) bp and nacl concentration (bp, 163+/-8 mm hg; nacl, 260 ...200616520400
risk assessment of acrylamide in foods.daily mean intakes of acrylamide present in foods and coffee in a limited norwegian exposure assessment study have been estimated to be 0.49 and 0.46 microg per kg body weight in males and females, respectively. testicular mesotheliomas and mammary gland adenomas have consistently been found in 2-year drinking water rat cancer studies with acrylamide. acrylamide also shows initiating activity in mouse skin after systemic administration. since acrylamide is converted to the mutagenic metabolite g ...200312805639
interrelationship between ectoparasites and wild rodents from northeastern buenos aires province, argentina.infestation parameters and indices of mites, ticks and fleas associated with wild rodents from northeastern buenos aires province, argentina, were studied. host species similarity was also analyzed in relation to their ectoparasites. fifty-five rodents were captured from january 2000 to march 2001. in total, 1,022 ectoparasites were collected and three ectoparasite-host associations were new records. however, this is the first study on craneopsylla minerva wolffhuegeli infesting parameters. ecto ...200312700861
a new genus of nippostrongylinae (nematoda: heligmonellidae) from the water rat scapteromys aquaticus (sigmodontinae) in argentina.a new genus of nippostrongylinae, malvinema n. gen., with 3 coparasitic species m. frederici n. sp., m. carolinae n. sp., and m. victoriae n. sp. from the intestine of the water rat, scapteromys aquaticus thomas (rodentia: muridae), from the northeast of buenos aires province, argentina, is proposed in this study. the new genus shows similarities to 2 neotropical nippostrongylinae: carolinensis (travassos, 1937) by some characters of the synlophe and stilestrongylus freitas, lent and almeida, 19 ...200312659314
[first report on leptospira interrogans in the sigmodontine rodent scapteromys aquaticusprimeiro relato da presença de leptospira interrogans em roedores sigmodontíneos scapteromys aquaticus].leptospirosis is a globally distributed zoonosis that can be transmitted through direct or indirect contact with the urine or tissues of infected animals. in argentina, leptospirosis is endemic in the province of santa fe and epidemic outbreaks occur during floods. however, very little is known about the role that wild rodents play in the spread of the disease in argentina. the objective of this study was to identify the host species of pathogenic leptospira among rodents in a riverine settlemen ...201831093111
an ecological field study of the water-rat nectomys squamipes as a wild reservoir indicator of schistosoma mansoni transmission in an endemic area.small mammals are found naturally infected by schistosoma mansoni, becoming a confounding factor for control programs of schistosomiasis in endemic areas. the aims of this study were: to investigate the infection rates by s. mansoni on the water-rat nectomys squamipes during four years in endemic areas of sumidouro, state of rio de janeiro, using mark-recapture technique; to compare two diagnostic methods for schistosomiasis; and to evaluate the effects of the chemotherapy in the human infected ...200617308757
description of the immature stages and redescription of the female of ixodes schulzei aragão & fonseca, 1951 (acari: ixodidae), an endemic tick species of brazil.ixodes schulzei aragão & fonseca, 1951 is a tick endemic to brazil, where nine species of ixodes latreille, 1796 are currently known to occur. larvae, nymphs and females of i. schulzei were obtained from a laboratory colony originating from an engorged female collected on a free-living water rat nectomys squamipes from the santa branca municipality, são paulo state. only female ticks were obtained from engorged nymphs. unfed immature and female adult specimens were measured and the descriptions ...200717896185
attenuation of n-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol-morin.morin (3,5,7,2',4'-pentahydroxyflavone), a plant-derived flavonoid belonging to the subclass of flavonol is believed to play a role in chemoprevention and cancer chemotherapy. in this study, we found that the cotreatment of morin (500 ppm in diet) for 16 weeks to n-nitosodiethylamine-induced (200 mg/kg bodyweight in drinking water) rats provides protection against the oxidative stress caused by the carcinogen and thereby prevents hepatocellular carcinogenesis. on administration of the carcinogen ...200817950263
a traditional chinese herbal antilithic formula, wulingsan, effectively prevents the renal deposition of calcium oxalate crystal in ethylene glycol-fed rats.we investigated the effects of a traditional chinese herbal formula, wulingsan (wls), on renal stone prevention using an ethylene glycol-induced nephrocalcinosis rat model. forty-one male sprague-dawley (sd) rats were divided into four groups. group 1 (n=8) was the normal control; group 2 (n=11) served as the placebo group, and received a gastric gavage of starch and 0.75% ethylene glycol (eg) as a stone inducer; group 3 received eg and a low dose of wls (375 mg/kg); and group 4 received eg and ...200818040675
[individual sensitivity of wistar rats to piracetam].effects of repeated piracetam (pir) injections in a dose of 40 and 250 mg/kg/day on the learning in water rats were studied. it has been found that character of the effects depends on typological features of the animals. rats with strong predominance of excitation (choleric type) showed low sensitivity to pir. small dose of pir provoked clear negative effect in rats with relative balance of the basic nervous processes: excitation and inhibition (sanguine and phlegmatic types). despite of express ...200718198598
biological implications of the phenotypic plasticity in the schistosoma mansoni-nectomys squamipes model.the water-rat nectomys squamipes is mostly important non-human host in schistosomiasis mansoni transmission in brazil, due to its susceptibility, high abundance and water-contact pattern. during experimental infection of n. squamipes with schistosoma mansoni, adult worms show phenotypic plasticity. this finding led us to investigate whether biological behavior is also affected. this was assessed comparing the biological characteristics of four s. mansoni strains: be (state of belém do pará), ce ...200818813763
mathevotaenia niuguiniensis n. sp. (cestoda: anoplocephalidae: linstowiinae) from the water-rat parahydromys asper (thomas) in papua new guinea, with a list of species of mathevotaenia akumyan, 1946.a new species of cestode, mathevotaenia niuguiniensis n. sp. (anoplocephalidae: linstowiinae), is described from the hydromyine rodent parahydromys asper (thomas) in papua new guinea. this is the third species of the genus reported from the australasian region. the new species differs from all congeners in rodents by having an elongate cirrus-sac, which crosses the osmoregulatory canals and extends into the medulla, compared with a short, ovoid cirrus-sac which does not penetrate into the medull ...200818815898
do schistosomes grow old? a confocal laser scanning microscopy study.infected hosts progressively decrease egg output during the chronic phase of schistosoma mansoni infection. ageing may be a factor that results in a progressive decrease in the ability to reproduce. this study was performed to gain insight into the effects of ageing on adult schistosomes, using confocal laser scanning microscopy. adult worms were recovered from experimentally infected nectomys squamipes (water rat). viable eggs were voided in the faeces for 65 weeks and, thereafter, only unviabl ...201019941681
coffee reduces liver damage in a rat model of steatohepatitis: the underlying mechanisms and the role of polyphenols and melanoidins.epidemiological data associate coffee consumption with a lower prevalence of chronic liver disease and a reduced risk of elevated liver enzyme levels (γ glutamyl transpeptidase and alanine aminotransferase), advanced liver disease and its complications, and hepatocellular carcinoma. knowledge of the mechanisms underlying these effects and the coffee components responsible for these properties is still lacking. in this study, 1.5 ml/day of decaffeinated coffee or its polyphenols or melanoidins (c ...201021038411
na+-cl- cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats.recently, in addition to epithelial sodium channel alpha-subunit (αenac), the thiazide-sensitive sodium-chloride cotransporter (ncc) and pendrin, also known as sodium-independent chloride/iodide transporter, were reported to be activated by aldosterone. here, we investigated whether chloride (cl-) is responsible for hypertension, inflammation, and renal damage in aldosterone-infused rats. following left nephrectomy, 8-wk-old male sprague-dawley rats were allocated into four groups: 1) drinking 1 ...201829631358
evaluation of immunological, parasitological and molecular methods for the diagnosis of schistosoma mansoni infection before and after chemotherapy treatment with praziquantel in experimentally infected nectomys squamipes.in low endemicity areas of schistosomiasis, the recommended diagnostic method of coprological examination results in an underestimation of infection cases. alternative diagnostic methods have been developed, such as immunodiagnostic and molecular techniques. in this study we evaluated three methods used in the diagnosis of schistosoma mansoni infection: parasitological (kato-katz), immunological (elisa) and molecular (real time pcr), and also investigated the sensitivity of each technique in the ...201121458922
biochemical and histological changes in liver of nectomys squamipes naturally infected by schistosoma mansoni.the south american water rat nectomys squamipes is a wild mammal reservoir of schistosoma mansoni in brazil. in the present study, wild rodents were collected in the field and categorized into two groups: infected and uninfected by s. mansoni. blood was collected to analyze changes in the serum glucose level (mg/dl) and liver fragments were used to determine the hepatic glycogen content (mg of glucose/g tissue). the histological examination showed inflammatory granulomatous lesions in different ...201424473876
paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats.macrophages in other organs (e.g. kidneys, lungs, and spleen, et. al) have rarely been reported in the development of liver fibrosis. therefore, it is important to investigate macrophage activation in the main organs in liver fibrosis. we investigated the potential antifibrogenic effects of paeoniflorin (pf) in a dimethylnitrosamine (dmn)-induced rat model with special focus on inhibiting macrophage activation in the main organs.201223237422
seroprevalence of leptospiral antibodies in rodents from riverside communities of santa fe, argentina.leptospirosis is a zoonotic disease that can be transmitted by contact with the urine of infected mammals. rodents play a mayor role in the transmission of leptospires to humans. the province of santa fe reports the greatest number of cases in argentina. yet, in this region, there are still knowledge gaps regarding the diversity of rodent species that may be hosts of pathogenic leptospires. the aims of this study were to evaluate the presence of leptospiral antibodies in rodents from three river ...202032330132
orthohantavirus genotype lechiguanas in oligoryzomys nigripes (rodentia: cricetidae): new evidence of host-switching.to identify and predict situations of increased risk of orthohantavirus infection in humans, it is necessary to study the relationships between the virus and its rodent hosts. the present study investigated orthohantavirus infection in an assemblage of wild sigmodontinae rodents of the paraná delta, argentina, and providing new evidence of host-switching events. rodents belonging to the species oxymycterus rufus (n = 187), akodon azarae (n = 82), oligoryzomys flavescens (n = 80), oligoryzomys ni ...201930599176
new species and records of the mite genus prolistrophorus (acariformes: listrophoridae) from rodents of the subfamily sigmodontinae (rodentia: cricetidae).six fur-mite species of the genus prolistrophorus fain, 1970 (acariformes: listrophoridae) were recorded from central and south american rodents of the subfamily sigmodontinae (rodentia: cricetidae). among them, prolistrophorus (aprolistrophorus) parabidentatus sp. nov. from akodon azarae from argentina and prolistrophorus (aprolistrophorus) tylomys sp. nov. from tylomys nudicaudus from guatemala are described as new for science. new hosts are recorded for the following species: prolistrophorus ...201425236266
daily movements and microhabitat selection of hantavirus reservoirs and other sigmodontinae rodent species that inhabit a protected natural area of argentina.abundance, distribution, movement patterns, and habitat selection of a reservoir species influence the dispersal of zoonotic pathogens, and hence, the risk for humans. movements and microhabitat use of rodent species, and their potential role in the transmission of hantavirus were studied in otamendi natural reserve, buenos aires, argentina. movement estimators and qualitative characteristics of rodent paths were determined by means of a spool and line device method. sampling was conducted durin ...201526063039
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