| bat lyssaviruses (aravan and khujand) from central asia: phylogenetic relationships according to n, p and g gene sequences. | bat lyssaviruses aravan and khujand were isolated in southern kyrgyzstan in 1991 and in northern tajikistan in 2001, respectively. preliminary studies with anti-nucleocapsid monoclonal antibodies suggested that the viruses were distinct from other lyssavirus serotypes. these data were supported by sequencing of the n gene of aravan virus. in the present study, we sequenced the entire n, p and g genes of both aravan and khujand viruses and compared them with respective sequences of other lyssavir ... | 2003 | 14602198 |
| isolation of irkut virus from a murina leucogaster bat in china. | bats are recognized as a major reservoir of lyssaviruses; however, no bat lyssavirus has been isolated in asia except for aravan and khujand virus in central asia. all chinese lyssavirus isolates in previous reports have been of species rabies virus, mainly from dogs. following at least two recent bat-associated human rabies-like cases in northeast china, we have initiated a study of the prevalence of lyssaviruses in bats in jilin province and their public health implications. a bat lyssavirus h ... | 2013 | 23505588 |
| comparative studies on the genetic, antigenic and pathogenic characteristics of bokeloh bat lyssavirus. | bokeloh bat lyssavirus (bblv), a novel lyssavirus, was isolated from a natterer's bat (myotis nattererii), a chiropteran species with a widespread and abundant distribution across europe. as a novel lyssavirus, the risks of bblv to animal and human health are unknown and as such characterization both in vitro and in vivo was required to assess pathogenicity and vaccine protection. full genome sequence analysis and antigenic cartography demonstrated that the german bblv isolates are most closely ... | 2014 | 24828330 |
| analysis of the complete genome of the first irkut virus isolate from china: comparison across the lyssavirus genus. | the genome of irkut virus, isolate irkv-thchina12, the first non-rabies lyssavirus from china (of bat origin), has been completely sequenced. in general, coding and non-coding regions of this viral genome are similar to those of other lyssaviruses. however, alignment of the deduced amino acid sequences of the structural proteins of irkv-thchina12 with those of other lyssavirus representatives revealed significant variability between viral species. the nucleoprotein and matrix protein were found ... | 2013 | 23872529 |
| [rabies in bats]. | rabies is a zoonosis ending fatally in all mammals, including humans. unlike the other mammals, this disease is usually not fatal in bats. rabies is caused by lyssaviruses which are divided into several distinct phylogroups comprising 15 known viruses. it is believed that the original hosts of all lyssaviruses are bats. classical rabies virus (rabv) occurs in bats across americas and represents the major cause of rabies in humans and domestic animals there. european bat lyssavirus type 1 (eblv-1 ... | 2016 | 27450525 |
| experimental infection of big brown bats (eptesicus fuscus) with eurasian bat lyssaviruses aravan, khujand, and irkut virus. | here we describe the results of experimental infections of captive big brown bats (eptesicus fuscus) with three newly isolated bat lyssaviruses from eurasia (aravan, khujand, and irkut viruses). infection of e. fuscus was moderate (total, 55-75%). there was no evidence of transmission to in-contact cage mates. incubation periods for irkut virus infection were significantly shorter (p < 0.05) than for either aravan or khujand virus infections. in turn, quantification of viral rna by taqman pcr su ... | 2006 | 16705370 |
| survey for bat lyssaviruses, thailand. | surveillance for lyssaviruses was conducted among bat populations in 8 provinces in thailand. in 2002 and 2003, a total of 932 bats of 11 species were captured and released after serum collection. lyssavirus infection was determined by conducting virus neutralization assays on bat serum samples. of collected samples, 538 were either hemolysed or insufficient in volume, which left 394 suitable for analysis. these samples included the following: pteropus lylei (n = 335), eonycteris spelaea (n = 45 ... | 2005 | 15752440 |