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new communesin derivatives from the fungus penicillium sp. derived from the mediterranean sponge axinella verrucosa.the ethyl acetate extract of penicillium sp., derived from the mediterranean sponge axinella verrucosa, yielded the known compound communesin b (1) and its new congeners communesins c (2) and d (3), as well as the known compounds griseofulvin, dechlorogriseofulvin, and oxaline. all structures were unambiguously established by 1d and 2d nmr and ms data. in several bioassays performed on different leukemia cell lines, the communesins exhibited moderate antiproliferative activity.200414738391
biosynthetic studies of marine lipids. 35. the demonstration of de novo sterol biosynthesis in sponges using radiolabeled isoprenoid precursors.1. de novo sterol biosynthesis in the sponges tethya aurantia and aplysina fistularis was investigated, using sodium [5,5-3h]-mevalonate, [1-3h]-farnesol and [3-3h]-squalene. [3-3h]-squalene was found to be the best precursor for demonstrating de novo sterol biosynthesis in a wider range of sponges. 2. by feeding [3-3h]-squalene and using cell-free techniques, the de novo sterol biosynthesis was established in 18 sponges belonging to nine orders. among these sponges were axinella polypoides and ...19911790671
fulvitalea axinellae gen. nov., sp. nov., a member of the family flammeovirgaceae isolated from the mediterranean sponge axinella verrucosa.the yellow-pigmented, non-motile, gram-negative, strictly aerobic, rod-shaped bacterial strain vi.18(t) was isolated from the mediterranean sponge axinella verrucosa collected off the coast near sdot yam, israel. results from 16s rrna gene sequence analysis indicated that the isolate belonged to the family flammeovirgaceae. the highest nucleotide similarity (91.4 %) occurred with aureibacter tunicatorum a5q-118(t). the predominant cellular fatty acids of strain vi.18(t) were iso-c15 : 0 (56.0 %) ...201322904228
aureivirga marina gen. nov., sp. nov., a marine bacterium isolated from the mediterranean sponge axinella verrucosa.two bacterial strains, vi.14 and viii.04(t), were isolated from the mediterranean sponge axinella verrucosa collected off the israeli coast near sdot yam. the non-motile, aerobic, gram-negative isolates were oxidase-negative and catalase-positive, and formed golden-brown colonies on marine agar 2216. the pigment was neither diffusible nor flexirubin-like. strain viii.04(t) grew at 15-37 °c, at ph 6.0-9.0, in the presence of 20-50 g nacl l(-1) and 20-80 g sea salts l(-1), the spectrum was narrowe ...201322707537
novel bioactive bromopyrrole alkaloids from the mediterranean sponge axinella verrucosa.the mediterranean sponge axinella verrucosa has been investigated for its alkaloid composition and has been found to produce a complex mixture of bromopyrrole alkaloids. along with the previously isolated compounds 5-18, four novel alkaloids of this class, compounds 1-4, have been isolated, and their structures established through spectroscopic methods. compounds 1-4 were found to display neuroprotective activity against the agonists serotonin and glutamate in vitro.200616169235
[further characterization of the orange carotenoid protein extracted from the marine demosponge axinella verrucosa].the orange coloration of the marine sponge a. verrucosa is provided by some carotenoids widespread in the ectosome and mesohyl of this sponge. these carotenoids are bound to a glyco(lipo)protein forming a non covalent complex. six carotenoids are bound to the glyco(lipo)protein, but only alpha-carotene was identified by hplc. the aminoacid composition is quite different from those previously reported in porifera. the content of ser and gly and the total polar residues are high. the presence of m ...19902100534
[caroteno-protein complexes in axinella verrucosa (porifera: demospongae)].carotenoproteins are common to a wide variety of animals, most notably invertebrates although other animal groups have been shown to have these complexes as well. in a previous paper alpha-carotene, renieratene, isorenieratene and an unknown isomer of renieratene were isolated, but at present nothing is known about nature of the carotenoid-protein complexes in a. verrucosa. in this paper we report our results about a carotenoid-protein complex extracted by triton x-100 and purified by sephadex g ...19892502159
high performance liquid chromatography and fast atom bombardment mass spectrometry of unusual branched and unsaturated phospholipid molecular species.the unusual symmetrical molecular species 1,2-di-3,7,11,15-tetramethylhexadecanoyl-sn-glycero-3-phosphoglyce rol, 1,2-di-5,8,11,14-docosatetraenoyl-sn-glycero-3-phosphocholine, 1,2-di-5,9,19-octacosatrienoyl-sn-glycero-3-phosphoethanolamine, and 1,2-di-5,9,23-triacontatrienoyl-sn-glycero-3-phosphoethanolamine were isolated from the marine sponges axinella verrucosa, higginsia tethyoides, tethya aurantia and aplysina fistularis by hplc and studied by fast atom bombardment (fab) mass spectrometry. ...19873594713
[carotenoids of axinella verrucosa (demosponge tetractinomorphae)]. 19761026244
metabolism in porifera iv. biosynthesis of the 3 beta-hydroxymethyl-a-nor-5 alpha-steranes from cholesterol by axinella verrucosa. 19751120497
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