Publications

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predicted disease susceptibility in a panamanian amphibian assemblage based on skin peptide defenses.chytridiomycosis is an emerging infectious disease of amphibians caused by a chytrid fungus, batrachochytrium dendrobatidis. this panzootic does not equally affect all amphibian species within an assemblage; some populations decline, others persist. little is known about the factors that affect disease resistance. differences in behavior, life history, biogeography, or immune function may impact survival. we found that an innate immune defense, antimicrobial skin peptides, varied significantly a ...200616870844
stability of microbiota facilitated by host immune regulation: informing probiotic strategies to manage amphibian disease.microbial communities can augment host immune responses and probiotic therapies are under development to prevent or treat diseases of humans, crops, livestock, and wildlife including an emerging fungal disease of amphibians, chytridiomycosis. however, little is known about the stability of host-associated microbiota, or how the microbiota is structured by innate immune factors including antimicrobial peptides (amps) abundant in the skin secretions of many amphibians. thus, conservation medicine ...201424489847
conservation and divergence in the frog immunome: pyrosequencing and de novo assembly of immune tissue transcriptomes.frogs are a diverse group of vertebrates for which limited genomic resources are available. natural frog populations face a multitude of threats, including habitat degradation, infectious disease, and environmental change. characterizing the functional genomics of anuran tissues in general - and the immune system in particular - will enhance our knowledge of genetic and epigenetic responses to environmental threats and inform conservation and recovery efforts.201424680726
fine scale gene flow and individual movements among subpopulations of centrolene prosoblepon (anura: centrolenidae).dispersal capabilities determine and maintain local gene flow, and this has implications for population persistence and/or recolonization following environmental perturbations (natural or anthropogenic), disease outbreaks, or other demographic collapses. to predict recolonization and understand dispersal capacity in a stream-breeding frog, we examined individual movement patterns and gene flow among four subpopulations of the neotropical glassfrog, centrolene prosoblepon, at a mid-elevation clou ...200818624225
toxicity of formulated glyphosate (glyphos) and cosmo-flux to larval colombian frogs 1. laboratory acute toxicity.the spraying of coca (erythroxylum coca) with glyphosate in colombia has raised concerns about possible impacts on amphibians. there are few toxicity data for species other than those from temperate regions, and these have not been generated with the combination of formulated glyphosate (glyphos) and the adjuvant, cosmo-flux (coca mix) as used in coca control in colombia. in order to characterize toxicity of the spray mixture to frogs from colombia, gosner stage-25 tadpoles of scinax ruber, dend ...200919672764
impact of daily variable temperatures in life-history traits of tropical anurans.anuran embryos and tadpoles are daily exposed to wide thermal variations in their ponds, with maximum temperatures at midday. the aim of this research was to study the impact of three daily variable thermal environments (with maximum experimental temperatures between 10:00 and 16:00 hours), on the survival, developmental time and body size of metamorphs of four tropical anuran species from lowland habitats in colombia. a total of 50 embryos (gosner stage ten) to metamorphosis (gosner stage 46) o ...201729465973
external reinfection of a fungal pathogen does not contribute to pathogen growth.chytridiomycosis is an emerging infectious disease of amphibians caused by the fungal pathogen batrachochytrium dendrobatidis (bd), which has led to devastating declines in amphibian populations worldwide. current theory predicts that bd infections are maintained through both reproduction on the host's skin and reinfection from sources outside of the host. to investigate the importance of external reinfection on pathogen burden, we infected captive-bred individuals of the highly susceptible pana ...201830128614
a polymorphism in oocyte pigmentation in natural populations of the glass frog espadarana prosoblepon (centrolenidae).the adaptive role of amphibian oocyte melanic pigmentation and its molecular control are still elusive. here we present evidence of a polymorphism in egg pigmentation in the emerald glass frog espadarana prosoblepon. in ecuadorian natural populations of this species, females can lay dark brown or pale eggs that develop into normal pigmented tadpoles and adults. this trait is a sex-limited phenotype that is inherited like a recessive allele that we called pale eggs like (pel). the pel phenotype i ...202032930380
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