| oleanane-type triterpenoids from the leaves and twigs of fatsia polycarpa. | seven new oleanane-type triterpenoids (1-7), named fatsicarpains a-g, and the known compounds 3a-hydroxyolean-11,13(18)-dien-28-oic acid (8) and 3a-hydroxyolean-11-en-28,13ß-olide (9) were isolated from the leaves and twigs of fatsia polycarpa on the basis of bioassay-guided fractionation. the structures of compounds 1-7 were elucidated through spectroscopic analyses and single-crystal x-ray crystallography of 1, 8, and 9. cytotoxicity against hepg2 2.2.15 and ags cells and antihepatitis b virus ... | 2011 | 21766884 |
| biological activity of oleanane triterpene derivatives obtained by chemical derivatization. | nine new derivatives of oleanane triterpenoids isolated from fatsia polycarpa hayata were synthesized through chemical transformations. acetylation was effected by reaction with acetic anhydride in pyridine to afford compounds 1-5, while compound 6 was obtained using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (edc·hcl) in ch2cl2. the others derivatives 7-9 were obtained in reactions of the corresponding triterpenoids with edc·hcl, 4-n,n-dimethylaminopyridine hydrochloride and 4- ... | 2013 | 24145793 |
| anti-inflammatory effects and mechanisms of fatsia polycarpa hayata and its constituents. | fatsia polycarpa, a plant endemic to taiwan, is an herbal medicine known for treating several inflammation-related diseases, but its biological function needs scientific support. thus, the anti-inflammatory effects and mechanisms of the methanolic crude extract (mce) of f. polycarpa and its feature constituents, that is, brassicasterol (a phytosterol), triterpenoids 3 α -hydroxyolean-11,13(18)-dien-28-oic acid (hoda), 3 α -hydroxyolean-11-en-28,13 β -olide (hoeo), fatsicarpain d, and fatsicarpai ... | 2013 | 24489593 |