| nucleotide and predicted amino acid sequence-based analysis of the avian metapneumovirus type c cell attachment glycoprotein gene: phylogenetic analysis and molecular epidemiology of u.s. pneumoviruses. | a serologically distinct avian metapneumovirus (ampv) was isolated in the united states after an outbreak of turkey rhinotracheitis (trt) in february 1997. the newly recognized u.s. virus was subsequently demonstrated to be genetically distinct from european subtypes and was designated ampv serotype c (ampv/c). we have determined the nucleotide sequence of the gene encoding the cell attachment glycoprotein (g) of ampv/c (colorado strain and three minnesota isolates) and predicted amino acid sequ ... | 2003 | 12682171 |
| development and evaluation of a blocking enzyme-linked immunosorbent assay for detection of avian metapneumovirus type c-specific antibodies in multiple domestic avian species. | the first cases of infection caused by avian metapneumoviruses (ampvs) were described in turkeys with respiratory disease in south africa during 1978. the causative agent was isolated and identified as a pneumovirus in 1986. ampvs have been detected in domestic nonpoultry species in europe, but tests for the detection of these viruses are not available in the united states. to begin to understand the potential role of domestic ducks and geese and wild waterfowl in the epidemiology of ampv, we ha ... | 2003 | 12904358 |
| [human metapneumovirus]. | the human metapneumovirus (hmpv) is a new pneumovirinae related to the avian metapneumovirus type c. hmpv genome differs from human respiratory syncytial virus (rsv) genome by the gene order and the lack of nonstructural genes. two genetic sub-groups and four sub-types of hmpv are identified. hmpv infections evolve as regular winter outbreaks which have roughly the same size and overlaping rsv epidemics. among hospitalized children in caen, hmpv is detected in 9.7% of the cases after rsv (37%), ... | 2009 | 18515017 |
| a family-wide rt-pcr assay for detection of paramyxoviruses and application to a large-scale surveillance study. | family-wide molecular diagnostic assays are valuable tools for initial identification of viruses during outbreaks and to limit costs of surveillance studies. recent discoveries of paramyxoviruses have called for such assay that is able to detect all known and unknown paramyxoviruses in one round of pcr amplification. we have developed a rt-pcr assay consisting of a single degenerate primer set, able to detect all members of the paramyxoviridae family including all virus genera within the subfami ... | 2012 | 22496880 |
| genetic diversity and evolution of human metapneumovirus fusion protein over twenty years. | human metapneumovirus (hmpv) is an important cause of acute respiratory illness in children. we examined the diversity and molecular evolution of hmpv using 85 full-length f (fusion) gene sequences collected over a 20-year period. | 2009 | 19740442 |