| ttv, a new human virus with single stranded circular dna genome. | tt virus (ttv) was found in 1997 from a hepatitis patient without virus markers. however, the real impact of ttv on liver diseases remains uncertain to date. due to the lack of suitable cell systems to support the growth of ttv, the biology of ttv is still obscure. this review tries to summarise the current status of ttv on aspects other than the taxonomic diversity of ttv. ttv was the first human virus with a single stranded circular dna genome. ttv was considered to be a member of circoviridae ... | 2002 | 11987140 |
| comparison of the structures of three circoviruses: chicken anemia virus, porcine circovirus type 2, and beak and feather disease virus. | circoviruses are small, nonenveloped icosahedral animal viruses characterized by circular single-stranded dna genomes. their genomes are the smallest possessed by animal viruses. infections with circoviruses, which can lead to economically important diseases, frequently result in virus-induced damage to lymphoid tissue and immunosuppression. within the family circoviridae, different genera are distinguished by differences in genomic organization. thus, chicken anemia virus is in the genus gyrovi ... | 2003 | 14645560 |
| avian circovirus diseases: lessons for the study of pmws. | the diseases associated with psittacine beak and feather disease virus (bfdv), pigeon circovirus (picv) and goose circovirus (gocv), which can be classified with porcine circovirus type 2 (pcv2) as members of the genus circovirus of the family circoviridae, have clinico-pathological features in common with post-weaning multisystemic wasting syndrome (pmws), with which pcv2 infection is causally associated. intracytoplasmic botryoid inclusions within macrophages and depletion of t and b lymphocyt ... | 2004 | 14741130 |
| identification of chicken anemia virus putative intergenotype recombinants. | chicken anemia virus (cav), the only member of the genus gyrovirus in the family circoviridae is the pathogen of chicken infectious anemia. it is unknown whether homologous recombination happens between cav strains. in order to gain insight into this matter, we have performed a phylogenetic analysis of full-length cav strains isolated to detect possible recombination events. two putative recombinants, sd24, sd22 and the putative parental-like strains were identified with the use of simplot progr ... | 2007 | 17618666 |
| relationship of torque teno virus to chicken anemia virus. | this chapter examines the correlation between torque teno virus (ttv) and chicken anemia virus (cav). each has a circular single-stranded (ss)dna genome with every one of its known open reading frames (orf) on its antigenomic strand. this structure is distinct from those of circoviruses. the genomic sizes of ttv and cav are different, 3.8 kb and 2.3 kb, respectively. while the spectrum of the ttv genome is enormously diverse, that of the cav genome is quite narrow. although a 36-nt stretch near ... | 2009 | 19230561 |
| chicken anemia virus. | chicken anemia virus (cav), the only member of the genus gyrovirus of the circoviridae, is a ubiquitous pathogen of chickens and has a worldwide distribution. cav shares some similarities with torque teno virus (ttv) and torque teno mini virus (ttmv) such as coding for a protein inducing apoptosis and a protein with a dual-specificity phosphatase. in contrast to ttv, the genome of cav is highly conserved. another important difference is that cav can be isolated in cell culture. cav produces a si ... | 2009 | 19230563 |
| discovery of a genome of a distant relative of chicken anemia virus reveals a new member of the genus gyrovirus. | a 2.4-kb phi29 polymerase amplification product from serum of a diseased chicken was cloned and sequenced. the 2383-nucleotide sequence showed about 40% identity to a representative genome of chicken anemia virus (cav), the only member of the genus gyrovirus, family circoviridae. the new genome had an organization similar to that of cav: a putative 5' untranscribed region of about 400 nt followed by three partially overlapping open reading frames encoding vp1, vp2 and vp3 homologs. the amino aci ... | 2011 | 21442232 |
| identification of the first human gyrovirus, a virus related to chicken anemia virus. | we have identified in a skin swab sample from a healthy donor a new virus that we have named human gyrovirus (hgyv), because of its similarity with the chicken anemia virus (cav), the only previously known member of the gyrovirus genus. in particular, this virus encodes an homolog of the cav apoptin, a protein that selectively induces apoptosis in cancer cells. by pcr screening, hgyv was found in 5 of 115 other non-lesional skin specimens, but in none of 92 bronchoalveolar lavages or nasopharyng ... | 2011 | 21632766 |
| high yield expression in a recombinant e. coli of a codon optimized chicken anemia virus capsid protein vp1 useful for vaccine development. | abstract: background: chicken anemia virus (cav), the causative agent chicken anemia, is the only member of the genus gyrovirus of the circoviridae family. cav is an immune suppressive virus and causes anemia, lymph organ atrophy and immunodeficiency. the production and biochemical characterization of vp1 protein and its use in a subunit vaccine or as part of a diagnostic kit would be useful to cav infection prevention. results: significantly increased expression of the recombinant full-length v ... | 2011 | 21781331 |
| variants of the recently discovered avian gyrovirus 2 are detected in southern brazil and the netherlands. | a genome of a virus preliminarily named avian gyrovirus 2 (agv2), a close relative to chicken anemia virus, was recently discovered in a chicken in the state of rio grande do sul, southern brazil. to study the occurrence of agv2 in rio grande do sul and the neighboring state santa catarina, a number of adult chickens (n=108 and n=48, respectively) were tested for the presence of agv2 dna. an agv2-specific pcr was developed, optimized and used to analyze dna extracted from clinical samples. agv2 ... | 2011 | 22018524 |