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byssovorax cruenta gen. nov., sp. nov., nom. rev., a cellulose-degrading myxobacterium: rediscovery of 'myxococcus cruentus' thaxter 1897.a rare, cellulose-decomposing myxobacterium is described, and a new genus name, byssovorax, is proposed for it. the organism is almost certainly identical to the species 'myxococcus cruentus' thaxter 1897, and that species epithet is therefore revived for the novel bacterium: the type strain of byssovorax cruenta gen. nov., sp. nov., nom. rev. is strain by c2(t) (=dsm 14553(t)=cip 108850(t)). the g+c content of its dna is 69.9 mol%. the 16s rrna gene sequence shows that the species belongs to th ...200617012562
cruentaren, a new antifungal salicylate-type macrolide from byssovorax cruenta (myxobacteria) with inhibitory effect on mitochondrial atpase activity. fermentation and biological properties.the novel macrolide cruentaren a was produced at levels up to 3.2 mg/liter by cultures of the myxobacterium byssovorax cruenta. the new compound strongly inhibited the growth of yeasts and filamentous fungi and showed high cytotoxicity against l929 mouse fibroblast cells. a minor co-metabolite of cruentaren a, named cruentaren b, and identified as a six-membered lactone isomer of cruentaren a, showed only marginal cytotoxicity and no antifungal activity. cruentaren a inhibited f0f1 mitochondrial ...200617191683
characterization of a defined cellulolytic and xylanolytic bacterial consortium for bioprocessing of cellulose and hemicelluloses.diminishing fossil fuel reserve and increasing cost of fossil hydrocarbon products have rekindled worldwide effort on conversion of lignocellloloses (plant biomass) to renewable fuel. inedible plant materials such as grass, agricultural, and logging residues are abundant renewable natural resources that can be converted to biofuel. in an effort to mimic natural cellulolytic-xylanolytic microbial community in bioprocessing of lignocelluloses, we enriched cellulolytic-xylanolytic microorganisms, p ...201120859703
phaselicystis flava gen. nov., sp. nov., an arachidonic acid-containing soil myxobacterium, and the description of phaselicystidaceae fam. nov.a bacterial strain designated sbko001(t) was isolated from a forest soil sample from mt makiling in laguna, philippines. it shows the general characteristics associated with myxobacteria, such as swarming of gram-negative, rod-shaped vegetative cells, fruiting body formation and bacteriolytic activity. the strain is mesophilic, strictly aerobic and chemoheterotrophic and also exhibits resistance to various antibiotics. major fatty acids are iso-c(15 : 0), c(17 : 1) 2-oh and c(20 : 4) (arachidoni ...200919502347
cruentaren a, a highly cytotoxic benzolactone from myxobacteria is a novel selective inhibitor of mitochondrial f1-atpases.cruentaren a, a new antifungal benzolactone produced by the myxobacterium byssovorax cruenta, proved to be highly cytotoxic against various human cell lines. it inhibited the proliferation of different cancer cell lines including a multidrug-resistant kb line at low nanomolar levels. it arrested human histocytic lymphoma cells (u-937) in g(0/1) phase, but did not trigger an apoptotic process. studies to uncover the molecular target of cruentaren a showed that the novel compound, despite its stru ...200717624334
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