| antifertility plant products: testicular cell population dynamicsfollowing solasodine (c27h43o2n) administration in rhesus monkey (macaca mulatta). | solasodine obtained from the solanum xanthocarpum berries was administered to rhesus monkeys for 150 days to evaluate their effect on testicular cell population dynamics. solasodine brings about an interference with spermiogenesis at the stage xii of late spermatids. the spermatids were decreased by 69% (p less than 0.001). no significant change was found in the population of spermatogonia/primary and secondary spermatocytes. the production of immature and mature leydig cells were decreased by 6 ... | 1989 | 2619100 |
| effects of alcoholic extract of solanum xanthocarpum seeds in adult male rats. | | 1988 | 3397114 |
| effect of solanum xanthocarpum and clerodendron serratum on histamine release from tissues. | | 1967 | 4172641 |
| cardiac stimulating effects of kantakari (solanum xanthocarpum). | | 1966 | 5974787 |
| chemical and pharmacological studies on solanum xanthocarpum (kantakari). | | 1967 | 6056284 |
| antispermatogenic/antiandrogenic properties of solasodine (c27h43o2n) obtained from solanum xanthocarpum berries on the male genital tract of dog (canis-familiaris). a histophysiological approach. | chronic administration of solasodine (20 mg/kg alt. day for 30 days) caused testicular lesions resulting in a severe impairment of spermatogenic elements. the epididymides were devoid of spermatozoa. total protein, sialic acid and glycogen contents of the testis and epididymis were reduced significantly whereas the testicular cholesterol was elevated. acid phosphatase enzyme activity of the testes was low after solasodine treatment. serum enzymes (sgpt, alkaline phosphatase) serum protein, trigl ... | 1982 | 7118268 |
| effects of short-term treatment of solasodine on cauda epididymis in dogs. | oral administration (80 mg/kg body wt/day for 30 days) of solasodine (extracted and isolated from the berries of the solanum xanthocarpum) to intact dogs significantly decreased the epithelial cell height of cauda epididymides. the cells became atrophic and the lumen was devoid of spermatozoa. castration followed by the adminstration of solasodine further reduced the epithelial cell height in comparison to castrated controls. concurrent treatment of solasodine along with testosterone propionate ... | 2002 | 12622179 |
| antifungal potential of indian medicinal plants. | fourteen indian plants, selected based on their use in respiratory and other disorders in traditional systems of medicine, were analyzed for their potential activity against fungi. the antifungal activity was investigated by disc diffusion, microbroth dilution and percent spore germination inhibition tests against pathogenic aspergilli. methanolic extracts of solanum xanthocarpum and datura metel inhibited the growth of aspergillus fumigatus, a. flavus and a. niger and their in vitro mics were f ... | 2004 | 15159003 |
| studies on hypoglycaemic activity of solanum xanthocarpum schrad. & wendl. fruit extract in rats. | aqueous extract of the fruits of solanum xanthocarpum schrad. & wendl. (solanaceae) was investigated for hypoglycaemic activity in rats and mice. screening for the hypoglycaemic activity was assessed on normoglycaemic, alloxan treated hyperglycaemic and glucose loaded rats along with in vitro study on glucose utilization by isolated rat hemidiaphragm. the various haematological and biochemical parameters were also studied. the extract was found to possess significant hypoglycaemic activity when ... | 2006 | 16829003 |
| repellency of volatile oils from moschosma polystachyum and solanum xanthocarpum against filarial vector culex quinquefasciatus say. | volatile oils extracted by steam distillation from leaves of two plant species moschosma polystachyum and solanum xanthocarpum were evaluated in mosquito cages for their topical repellency effects against filarial vector culex quinquefasciatus. the oil from m. polystachyum was tested at four different concentrations ranging from 1 to 4%. the 4% concentration gave 332.2 minutes protection whereas control gave only 4.4 minutes protection against mosquito bites. however, the volatile oil of s.xanth ... | 2005 | 16883279 |
| isolation of steroidal glycosides from solanum xanthocarpum and studies on their antifungal activities. | isolation of the methanol extract of solanum xanthocarpum resulted in the isolation and characterization of carpesterol (1) and four steroidal glycosides (2, 3, 4, and 5). the structures of these compounds were established by spectroscopic analysis. the antifungal activity of the steroidal compounds extracted from the fruits of s. xanthocarpum was investigated against aspergillus niger and trichoderma viride. the isolated compounds 1, 2, 3, 4, and 5 exhibited inhibitory effects on the radial gro ... | 2007 | 17613815 |
| in vitro screening for the tumoricidal properties of international medicinal herbs. | there is growing use of anticancer complementary and alternative medicines (cams) worldwide. the purpose of the current study is to assess a sizeable variety of natural and plant sources of diverse origin, to ascertain prospective research directives for cancer treatment and potential new chemotherapy drug sources. in this study, 374 natural extracts (10 microg/ml-5 mg/ml) were evaluated for dose-dependent tumoricidal effects using immortal neuroblastoma of spontaneous malignant origin. the find ... | 2009 | 18844256 |
| evaluation of larvicidal efficacy of solanum xanthocarpum storage against vector mosquitoes in north - western rajasthan. | efficacy of the methanol extracts from fruits without seeds, whole yellow ripe fruits and seeds of the plant solanum xanthocarpum was evaluated against larvae of anopheles culicifacies, anopheles stephensi, aedes aegypti and culex quinquefasciatus, the important vector mosquitoes prevalent in the arid region. experiments were carried out on late 3rd or early 4th instar larvae of these mosquitoes using standard who technique. 24 and 48 hr lc50 and lc90 values along with their fiducial limits, reg ... | 2009 | 20143723 |
| effect of crude extract of solanum xanthocarpum against snails and mosquito larvae. | the ethanolic crude extract from solanum xanthocarpum was investigated for its molluscicidal activity against biomphalaria glabrata, the snail vector of schistosoma mansoni, and indoplanorbis exustus, the snail vector of intestinal echinostomiasis and schistosoma spindale, together with the larvicidal activity against the larvae of aedes aegypti, mosquito vector of dengue hemorrhagic fever and culex quinquefasciatus, the mosquito vector of urban bancroftian filariasis. the bioassays were carried ... | 2010 | 20578514 |
| study of the synergistic anti-inflammatory activity of solanum xanthocarpum schrad and wendl and cassia fistula linn. | nonsteroidal and steroidal drugs are generally used as a part of drug therapy in inflammation. however, these drugs have severe side-effects like nausea and vomiting. therefore, there is a need to identify anti-inflammatory compounds that will be effective with a better safety profile. solanum xanthocarpum schrad and wendl and cassia fistula linn has many therapeutic uses mentioned in ayurveda and therefore we aimed to study its anti-inflammatory activity both alone and in combination. | 2010 | 21170209 |
| Hepatoprotective effect of Solanum xanthocarpum fruit extract against CCl(4) induced acute liver toxicity in experimental animals. | To investigate the hepatoprotective potential of Solanum xanthocarpum (Solanaceae) (S. xanthocarpum) in experimental rats to validate its traditional claim. | 2011 | 22118032 |
| Antihyperglycemic and antioxidant effects of Solanum xanthocarpum leaves (field grown & in vitro raised) extracts on alloxan induced diabetic rats. | To investigate antidiabetic efficacy of the extract of field grown and in vitro raised leaves of Solanum xanthocarpum (S. xanthocarpum) against alloxan induced diabetic rats. | 2011 | 22014732 |
| potential wound healing activity of the ethanolic extract of solanum xanthocarpum schrad and wendl leaves. | the present work objective are to investigate indigenous plants used in wound healing in india, we hereby reported our findings related to wound healing activities of plant solanum xanthocarpum schrad and wendl (solanaceae) from some in vitro and in vivo model studies. the plant ethanolic extracts of the leaves of solanum xanthocarpum was identified qualitative phytochemical constituents and tested wound healing activity. the important secondary metabolites alkaloid, glycosides, saponins, carboh ... | 2012 | 22186329 |
| evaluation of antimicrobial activity and bronchodialator effect of a polyherbal drug-shrishadi. | to investigate antimicrobial and bronchodialator effect of hydroalcholic extract of polyherbal drug shirishadi containing shirisha (albezzia lebbeck), nagarmotha (cyprus rotandus) & kantakari (solanum xanthocarpum). | 2012 | 23569869 |
| evaluation of antihepatotoxic potential of solanum xanthocarpum fruit extract against antitubercular drugs induced hepatopathy in experimental rodents. | to assess the hepatoprotective effect of solanum xanthocarpum (s. xanthocarpum) fruit extract against antitubercular drug-induced liver toxicity in experimental animals. | 2012 | 23569949 |
| phytochemical and antimicrobial studies of extracts of solanum xanthocarpum. | antibacterial activity pf various parts (stem, leaf and fruits) of solvent extracts (petroleum ether, alcohol and acetone) of solanum xanthocarpum against escherichia coli, klebsiella pneumoniae, salmonella typhi and bacillus cereus were detected by zone of inhibition. the extracts of solanum xanthocarpum showed high sensitivity to kiebsiella pneumoniae and salmonella typhi, moderate sensitivity to escherichia coli and less sensitivity and resistant to bacillus cereus. in control, there is no in ... | 2003 | 22557117 |
| phytochemical and antimicrobial studies of extracts of solanum xanthocarpum. | antibacterial activity of various parts (stem, leaf and fruits) of solvent extracts (petroleum ether, alcohol and acetone) of solanum xanthocarpum against escherichia coil, klebsiella of solanum xanthocarpum showed high sensitivity to escherichia coil & less sensitivity and resistance to bacillus cereus. in control, no inhibitory zone was observed. | 2004 | 22557158 |
| mosquito larvicidal and pupicidal efficacy of solanum xanthocarpum (family: solanaceae) leaf extract and bacterial insecticide, bacillus thuringiensis, against culex quinquefasciatus say (diptera: culicidae). | the bio-efficacy of solanum xanthocarpum leaf extract and bacterial insecticide, bacillus thuringiensis, were assessed against the first to fourth instar larvae and pupae of culex quinquefasciatus, under the laboratory conditions. the medicinal plants were collected from the outskirt bharathiar university, coimbatore, tamil nadu, india. the shade dried plant materials were extracted by employing the soxhlet apparatus with ethanol (organic solvent) for 8 h and filtered. the extracts were concentr ... | 2012 | 22215195 |
| green synthesis of silver nanoparticles through reduction with solanum xanthocarpum l. berry extract: characterization, antimicrobial and urease inhibitory activities against helicobacter pylori. | a green synthesis route for the production of silver nanoparticles using methanol extract from solanum xanthocarpum berry (sxe) is reported in the present investigation. silver nanoparticles (agnps), having a surface plasmon resonance (spr) band centered at 406 nm, were synthesized by reacting sxe (as capping as well as reducing agent) with agno(3) during a 25 min process at 45 °c. the synthesized agnps were characterized using uv-visible spectrophotometry, powdered x-ray diffraction, and transm ... | 2012 | 22949839 |
| evaluation of antiplasmodial activity of medicinal plants from north indian buchpora and south indian eastern ghats. | development of resistance against the frontline anti-malarial drugs has created an alarming situation, which requires intensive drug discovery to develop new, more effective, affordable and accessible anti-malarial agents. | 2015 | 25879738 |
| mosquitocidal activity of solanum xanthocarpum fruit extract and copepod mesocyclops thermocyclopoides for the control of dengue vector aedes aegypti. | the present study was carried out on solanum xanthocarpum fruit extract and copepods mesocyclops thermocyclopoides, which were assessed for the control of dengue vector, aedes aegypti, under laboratory conditions. the medicinal plants were collected from the outskirts of bharathiar university, coimbatore, tamil nadu, india. the shade-dried fruit materials were extracted by employing the soxhlet apparatus with methanol (organic solvent) 8 h and the extracts were filtered through a buchner funnel ... | 2012 | 22398832 |
| larvicidal activity of the extracts from different parts of the plant solanum xanthocarpum against important mosquito vectors in the arid region. | larvicidal efficacy of the aqueous and methanol extracts from green unripe and yellow ripe fruits, seeds, leaves and roots of the plant solanum xanthocarpum was evaluated against anopheles culicifacies, anopheles stephensi, aedes aegypti and culex quinquefasciatus, the important mosquito vectors prevalent in the arid region. studies were carried out on late 3rd orearly 4th instarlarvae of these species using standard who technique. based on concentration mortality data lc50 and lc90 values along ... | 2009 | 20121022 |
| bioactivity studies of the individual ingredients of the dashamularishta. | the bioactivity studies of the individual ingredients of dashamularishta--a classical ayurvedic preparation were done with the aqueous extracts of the individual ingredients. the aegle marmelos correa. exhibited severe toxicity to the brine shrimp (bst) nauplii, wheat rootlet growth (wrg) inhibition bioassay and lettuce seed germination (lsg) bioassay. it exhibited no inhibition to the growth of ppr and reo virus in vero cell line. the oroxylum indicum exhibited moderate toxicity to the bst and ... | 2004 | 16414581 |
| traditional uses of medicinal plants reported by the indigenous communities and local herbal practitioners of bajaur agency, federally administrated tribal areas, pakistan. | in the study area, knowledge related to the traditional uses of medicinal plants is totally in the custody of elder community members and local herbalists. the younger generation is unaware of the traditional knowledge, however with only few exceptions. therefore, this study was planned with objective to document the medicinal importance of plants, conserve this precious indigenous knowledge, and share it among other communities through published literature. | 2017 | 28108383 |
| comparative efficacy of solanum xanthocarpum extracts alone and in combination with a synthetic pyrethroid, cypermethrin, against malaria vector, anopheles stephensi. | with a goal of minimal application of environmentally hazardous chemical insecticides, the larvicidal activity of cypermethrin was studied alone and in combination with the root extract of solanum xanthocarpum against anopheline larvae. petroleum ether extract was observed to be the most toxic, with lc,, of 1.41 and 0.93 ppm and lc90 of 16.94 and 8.48 ppm at 24 and 48 hours after application, respectively, followed by carbon tetrachloride and methanol extracts. the values for cypermethrin were a ... | 2007 | 17539274 |
| evaluation of solanum xanthocarpum extracts as mosquito larvicides. | mosquito larvicidal activity of crude carbon-tetra-chloride, methanol and petroleum ether extracts of solanum xanthocarpum fruits was examined against anopheles stephensi and culex quinquefasciatus. among the extracts tested, carbon-tetra-chloride extract was the most effective with lc50 values of 5.11 ppm after 24 hours and 1.27 ppm after 48 hours of treatment against an. stephensi. in the case of cx. quinquefasciatus the petroleum ether extract was observed as most toxic with lc50 values of 62 ... | 2005 | 16334274 |
| toxicology of a potential molluscicide derived from the plant solanum xanthocarpum: a preliminary study. | a potential molluscicidal extract, obtained from the indigenous chinese plant solanum xanthocarpum (schrad. and wendl), was tested for toxicity against snails and fish in static, acute-toxicity tests. the extract had a significant effect on mature and young snails of the amphibious asian freshwater prosobranch oncomelania hupensis (gredler) and also on mature specimens of the freshwater pulmonate snails biomphalaria glabrata (say) and lymnaea stagnalis (linnaeus). the minimum dose that produced ... | 2002 | 12061979 |
| combination larvicidal action of solanum xanthocarpum extract and certain synthetic insecticides against filarial vector, culex quinquefasciatus (say). | the combination activities of temephos, fenthion and petroleum ether extract of solanum xanthocarpum were observed for their larvicidal activities against culex quinquefasciatus. the combination of temephos and s. xanthocarpum was studied at ratios of 1:1, 1:2, and 1:4. similar ratios were also used for the combination of fenthion and s. xanthocarpum. the temephos/plant extract combination acted antagonistically. the combination of fenthion and plant extract acted synergistically against the tar ... | 2010 | 20578513 |