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antiatherosclerotic effects of artemisia princeps pampanini cv. sajabal in ldl receptor deficient mice.antiatherosclerotic effects of ethanolic extracts of artemisia princeps pampanini cv. sajabal (esj) were investigated in low-density lipoprotein receptor deficient (ldlr(-/-)) mice. the western diet-induced high levels of total cholesterol and triglyceride were similar in the esj and control groups. however, circulating oxidized ldl was significantly decreased in the esj group (p < 0.05). esj also markedly decreased aortic expression levels of intercellular adhesion molecule-1 (icam-1), vascular ...200919166336
fragrant unsaturated aldehydes elicit activation of the keap1/nrf2 system leading to the upregulation of thioredoxin expression and protection against oxidative stress.thioredoxin, a key molecule in redox regulation, and many redox enzymes are regulated through the antioxidant responsive element (are). to search for antioxidative constituents, we screened extracts from vegetables and found that the extracts of perilla frutescens and artemisia princeps have potent thioredoxin-inducing activities. by activity-guided purification of perilla frutescens extracts, we identified perillaldehyde as a novel thioredoxin inducer. fragrant unsaturated aldehydes, such as tr ...200919123792
the ethanol extract from artemisia princeps pampanini induces p53-mediated g1 phase arrest in a172 human neuroblastoma cells.in the present study, the antiproliferative effects of the ethanol extract of artemisia princeps pampanini (eapp) and the mechanism involved were investigated. of the various cancer cells examined, human neuroblastoma a172 cells were most sensitive to eapp, and their proliferation was dose- and time-dependently inhibited by eapp. dna flow cytometry analysis indicated that eapp notably induced the g(1) phase arrest in a172 cells. of the g(1) phase cycle-related proteins examined, the expressions ...200818598164
antiasthmic effect of fermented artemisia princeps in asthmic mice induced by ovalbumin.artemisia princeps pampanini (ap) was fermented with bifidobacterium infantis k-525 and its antiasthmic effect investigated. ap and fermented ap (fap) reduced the ige level in the blood of ovalbumin-induced asthmic mice. moreover, fap reduced the ige, proinflammatory cytokine il-6, and il-4 levels in the trachea, as well as in the lung of the experimental asthmic mice, whereas ap only reduced the ige and il-6 levels in the lungs. nonetheless, ap and fap both inhibited the mrna expression of il-6 ...200718062237
the anti-diabetic effects of ethanol extract from two variants of artemisia princeps pampanini in c57bl/ksj-db/db mice.the anti-diabetic effects of two variants of artemisia princeps pampanini, sajabalssuk (sb) and sajuarissuk (ss), were investigated in type 2 diabetic animal using their ethanol extracts. male c57bl/ksj-db/db (db/db) mice were divided into control, sb ethanol extract (sbe), ss ethanol extract (sse), or rosiglitazone (rg) groups and their age-matched littermates (db/+) were used. supplementation of the sbe (0.171 g/100g diet), sse (0.154 g/100g diet), and rg (0.005 g/100g diet) improved glucose a ...200717574717
the effect of essential oils of dietary wormwood (artemisia princeps), with and without added vitamin e, on oxidative stress and some genes involved in cholesterol metabolism.wormwood (artemisia princeps) due to the abundance of antioxidant in its essential oils (eo), has been used as a traditional drug and health food in korea. oxidative stress plays an important role in the etiology of atherosclerosis thus antioxidative chemicals improves hepatic lipid metabolism partly by reducing oxysterol formation. the antioxidant activity was assessed using two methods, human low-density lipoprotein (ldl) oxidation and the anti-dpph free radical assays. it was found that the a ...200717368686
lactic acid bacteria increase antiallergic effect of artemisia princeps pampanini ss-1.artemisia princeps pampanini, which is called ssajuarissuk in korean (ss-1), was fermented with lactic acid bacteria (lab) and their passive cutaneous anaphylaxis reaction-inhibitory activity was investigated. of these fermented agents, ss-1 extract fermented with bifidobacterium infantis k-525 (f-ss-1) most effectively inhibited the release of p-hexosamindase from rbl-2h3 cells induced ige. in ige-induced rbl-2h3 cells, f-ss-1 inhibited proinflammatory cytokines il-6 and tnf-alpha mrna expressi ...200617024848
in vitro antioxidant and anti-inflammatory activities of jaceosidin from artemisia princeps pampanini cv. sajabal.oxidized low-density lipoprotein (oxldl) plays a key role in the inflammatory processes of atherosclerosis. jaceosidin isolated from the methanolic extracts of the aerial parts of artemisia princeps pampanini cv. sajabal was tested for antioxidant and anti-inflammatory activities. jaceosidin inhibited the cu(2+)-mediated ldl oxidation with ic(50) values of 10.2 microm in the thiobarbituric acid-reactive substances (tbars) assay as well as the macrophage-mediated ldl oxidation. the antioxidant ac ...200818449499
a cytotoxic and apoptosis-inducing sesquiterpenoid isolated from the aerial parts of artemisia princeps pampanini (sajabalssuk).repeated silica gel and octadecyl silica gel (ods) column chromatography of the aerial parts of artemisia princeps pampanini (sajabalssuk) led to the isolation of a new sesquiterpenoid, 3-((s)-2-methylbutyryloxy)-costu-1(10),4(5)-dien-12,6 alpha-olide (2), along with two previously reported sesquiterpenoids: 8 alpha-angeloyloxy-3beta,4 beta-epoxy-6 beta h,7 alpha h,8 beta h-guaia-1(10),11(13)-dien-12,6 alpha-olide (1, carlaolide b) and 3beta,4 beta-epoxy-8 alpha-isobutyryloxy-6 beta h,7 alpha h, ...200818670120
eupatilin, isolated from artemisia princeps pampanini, enhances hepatic glucose metabolism and pancreatic beta-cell function in type 2 diabetic mice.eupatilin (5,7-dihydroxy-3',4',6-trimethoxyflavone) was isolated from artemisia princeps to investigate the dose-response effects on blood glucose regulation and pancreatic beta-cell function in type 2 diabetic mice. db/db mice were divided into control (eupatilin-free, ain-76 standard diet), low-eupa (0.005g/100g diet) and high-eupa (0.02g/100g diet) groups. the supplementation of eupatilin for 6 weeks significantly lowered fasting blood glucose concentration while it increased hepatic glycogen ...200818703253
inhibitory effects of polyphenols in leaves of artemisia princeps pamp on protein fragmentation by cu(ii)-h2o2 in vitro.the leaves of artemisia princeps pamp have traditionally been used as teas and foods in japan. polyphenols in artemisia plants have been shown to have inhibitory effects against biological damages. the inhibitory effects of polyphenols in the leaves of a. princeps pamp were investigated on protein fragmentation induced by cu(ii)-h(2)o(2) in vitro. the total polyphenol content in the leaves of a. princeps pamp was 4.58%. the condensed tannin content was 0.62% by vanillin assay and 0.14% by proant ...200415117553
growth-inhibiting effects of seco-tanapartholides identified in artemisia princeps var. orientalis whole plant on human intestinal bacteria.the present work aimed at isolating antibacterial constituents from the whole plant of artemisia princeps var. orientalis active towards nine human intestinal bacteria.200312807448
development of scar marker for discrimination of artemisia princeps and a. argyi from other artemisia herbs.some artemisia herbs are used for medicinal purposes. in particular, a. princeps and a. argyi are classified as 'aeyup' and are used as important medicinal material in traditional korean medicine. on the other hand, a. capillaris and a. iwayomogi, which are classified as 'injinho' and 'haninjin', respectively, are used for other purposes distinct from those of 'aeyup'. however, sometimes 'aeyup' is not clearly discriminated from 'injinho' and/or 'haninjin'. furthermore, artemisia capillaris and/ ...200616595892
antimutagenicity of japanese traditional herbs, gennoshoko, yomogi, senburi and iwa-tobacco.the multistage induction theory is generally regarded as the mechanism of carcinogenesis. in order to prevent the initiation stage of carcinogenesis, it is meaningful to discover the functional components of edible plants. the objective of this research was to test the antimutagenicity of the functional components of several typical traditional herbs used in japan. the traditional herbs, gennoshoko (geranium nepalense var. thunbergii), yomogi (artemisia vulgaris var. indica), senburi (swertia ja ...200415630266
the antioxidative activity of traditional japanese herbs.the objective of this research was to examine the radical scavenging activity of traditional japanese herbs. samples used in the experiments were gennoshoko (geranium nepalense var. thunbergii), yomogi (artemisia vulgaris var.indica), senburi (swertia japonica), iwa-tobacco (conandron ramondioides), sarunokoshikake (elfvingia applanata), kanzo (glycyrrhiza uralensis fisch) and matatabi (actinidia polygama). the water-soluble components of the herbs were extracted in boiling water, and the volati ...200415630212
synergistic induction of 1,25-dihydroxyvitamin d(3)- and all-trans-retinoic acid-induced differentiation of hl-60 leukemia cells by yomogin, a sesquiterpene lactone from artemisia princeps.many anti-inflammatory agents are known to significantly enhance the terminal differentiation of some cancer cells such as leukemia cells. in this study, the effect of yomogin, a eudesmane sesquiterpene lactone isolated from artemisia princeps with anti-inflammatory activity, was investigated in human promyelocytic leukemia hl-60 cells. yomogin by itself induced small increases in cell differentiation, with less than 19 % of the cells attaining a differentiated phenotype. importantly, yomogin sy ...200212391550
selective activation of heparin cofactor ii by a sulfated polysaccharide isolated from the leaves of artemisia princeps.while checking anticoagulant activities in crude fractions from wakan-yakus (traditional herbal drugs), we detected antithrombin activity in the polysaccharide fraction of the leaves of artemisia princeps pamp. a sulfated polysaccharide purified from the crude fractions by ion-exchange chromatography on deae-cellulose and gel filtration on sepharose 6b potentiated the heparin cofactor ii (hc ii)-dependent antithrombin activity but not the antithrombin activity of antithrombin iii (at iii). the p ...19958562835
anti-complementary neutral polysaccharides from leaves of artemisia princeps.the three anti-complementary neutral polysaccharides, ia-1, ib-1 and ic-1, were purified from the leaves of artemisia princeps by anion-exchange chromatography, gel filtration and affinity chromatography. the order of the anti-complementary activity was ia-1 > ib-1 > ic-1. the polysaccharides appeared to be homogeneous from the results of gel filtration, hplc and electrophoresis. the m(r)s of ia-1 ib-1 and ic-1 were estimated to be 56,000, 16,000, and 7000, respectively, by hplc. ia-1 consisted ...19947764377
chemical analysis and antifungal activity of the essential oil of calea clematidea.the chemical composition of the essential oils of calea clematidea baker obtained by hydrodistillation of the leaves and flowers was analysed by gc and gc/ms and the oils were assayed for their antifungal activities. the essential oil of the leaves showed a high content of a new natural epoxy terpenoid, named clemateol (ca. 70 %), with minor amounts of o-vanillin (6.5 %), spathulenol (4.2 %), alpha-terpinene (4.0 %), germacrene b (2.9 %), yomogi alcohol (1.8 %), ( e)-caryophylene (1.7 %), m-cyme ...200212357399
possible mechanism of the stimulatory effect of artemisia leaf extract on the proliferation of cultured endothelial cells: involvement of basic fibroblast growth factor.to investigate the possible mechanism of the stimulatory effect of a hot water extract from artemisia leaf (artemisia princeps panpanini) (afe) on the proliferation of endothelial cells, cells from bovine aorta were cultured for 72 h in rpmi1640 medium supplemented with 10% fetal calf serum in the presence of 5 micrograms/ml afe. the afe treatment significantly increased the cell number after culture, while in the presence of 10 micrograms/ml unfractionated heparin, afe conversely decreased it. ...19902285980
mode of complement activation by acidic heteroglycans from the leaves of artemisia princeps pamp.the mode of action of the anti-complementary acidic heteroglycans, aaf-iib-2 and iib-3 which consisted of rhamnogalacturonan core and arabinogalactan moieties, purified from the leaves of artemisia princeps pamp (japanese name = gaiyo) were investigated. the anti-complementary activities of aaf-iib-2 and iib-3 were reduced partially in the absence of ca2+ ions. a marked consumption of c4 was observed to have occurred when serum was incubated with both polysaccharides in the presence of ca2+ ions ...19911797428
inhibitory effect of eupatilin and jaceosidin isolated from artemisia princeps on carrageenan-induced inflammation in mice.artemisia princeps pampanini (family asteraceae) is an herbal medicine widely used as a hepatoprotective, antioxidative, anti-inflammatory, and antibacterial agent in korea, china, and japan.200919505561
eupatilin inhibits t-cell activation by modulation of intracellular calcium flux and nf-kappab and nf-at activity.eupatilin, one of the pharmacologically active ingredients of artemisia princeps, exhibits a potent anti-ulcer activity, but its effects on t-cell immunity have not been investigated. here, we show that eupatilin has a profound inhibitory effect on il-2 production in jurkat t cells as well as in human peripheral blood leukocytes. eupatilin neither influenced clustering of cd3 and lfa-1 to the immunological synapse nor inhibited conjugate formation between t cells and b cells in the presence or a ...200919565564
antilipogenic and hypolipidemic effects of ethanol extracts from two variants of artemisia princeps pampanini in obese diabetic mice.the objective of this study was to determine the effects of the ethanol extract of two variants of artemisia princeps pampanini, sajabalssuk (sb) and sajuarissuk (ss), on lipid metabolism in type 2 diabetic animals. male c57bl/ksj-db/db mice were divided into control, sb ethanol extract (sbe) (0.171 g/100 g of diet), ss ethanol extract (sse) (0.154 g/100 g of diet), and rosiglitazone (rg) (0.005 g/100 g of diet) groups. supplementation of sbe and sse significantly lowered the plasma levels of fr ...200920041776
eupafolin, a flavonoid isolated from artemisia princeps, induced apoptosis in human cervical adenocarcinoma hela cells.although eupafolin, a flavone found in artemisia princeps pampanini, has been shown to inhibit the growth of several human cancer cells, its mode of action is poorly understood. in this study, we investigated the pro-apoptotic activities of eupafolin in human cervical carcinoma hela cells. it was found that eupafolin induced apoptosis in a dose-dependent manner, as evidenced by dna fragmentation and the accumulation of positive cells for annexin v. in addition, eupafolin triggered the activation ...201020397191
essential-oil composition, antileishmanial, and toxicity study of artemisia abyssinica and satureja punctata ssp. punctata from ethiopia.essential oils of artemisia abyssinica and satureja punctata ssp. punctata from ethiopia were analyzed by gc and gc/ms, and screened for leishmanicidal activity against promastigote and axenic amastigotes of leishmania donovani and l. aethiopica, including toxicity studies on human monocytic leukemia cells (thp-1) and erythrocytes in vitro. gc/ms of a. abyssinica oil revealed 67 compounds (99.94%) with the major constituents yomogi alcohol (38.47%), artemisyl acetate (24.88%), and artemisia alco ...201020397218
artemisia princeps var orientalis induces apoptosis in human breast cancer mcf-7 cells.dried leaves of artemisia princeps var orientalis are used in the eastern practice of moxibustion to improve general health. the ability of a. princeps smoke and water extracts to induce apoptosis was evaluated in human breast cancer mcf-7 cells in vitro.200718225547
anti-scratching behavioral effect of the essential oil and phytol isolated from artemisia princeps pamp. in mice.the anti-scratching behavioral effect of the essential oil and phytol isolated from artemisia princeps pamp. (ap, family asteraceae), which is widely used in traditional medicine for inflammatory diseases, was investigated in vivo. treatment of mice with ap essential oil (apeo) and phytol inhibited histamine- and compound 48/80-induced scratching behaviors. the anti-scratching behavioral effects of apeo and phytol are in proportion to their vascular permeability-inhibitory effects. these agents ...201120645242
neuroprotective effect of caffeoylquinic acids from artemisia princeps pampanini against oxidative stress-induced toxicity in pc-12 cells.phenolics in dry artemisia princeps pampanini, an herbal plant traditionally consumed as food ingredients in korea was extracted, fractionated, and quantified as well as evaluated for its neuroprotection for pc-12 cells. whole extract had 5,852 mg gallic acid equivalents/100 g of total phenolics and 6,274 mg and 9,698 mg vitamin c equivalents/100 g of antioxidant capacities assayed by dpph and abts radicals, respectively. the fraction extracted with n-butanol had the highest levels of total phen ...201121535743
a stimulatory effect of artemisia leaf extract on the proliferation of cultured endothelial cells.to investigate the effect of the hot water extract from artemisia leaf (artemisia princeps panpanini) (afe) on the proliferation of endothelial cells, the cells from bovine aorta were cultured for up to 96 h in the presence of 1, 5, 10 or 50 micrograms/ml afe in rpmi1640 medium supplemented with 10% fetal bovine serum. after a 72 h culture, the cell number was significantly increased by afe at 1, 5 and 10 micrograms/ml. an increase in the cell number by 5 micrograms/ml afe observed after a 72 or ...19902337970
artemisia princeps pamp. essential oil and its constituents eucalyptol and +¦-terpineol ameliorate bacterial vaginosis and vulvovaginal candidiasis in mice by inhibiting bacterial growth and nf-+¦b activation.to investigate the inhibitory effects of artemisia princeps pamp. (family asteraceae) essential oil (apeo) and its main constituents against bacterial vaginosis and vulvovaginal candidiasis, their antimicrobial activities against gardnerella vaginalis and candida albicans in vitro and their anti-inflammatory effects against g. vaginalis-induced vaginosis and vulvovaginal candidiasis were examined in mice. apeo and its constituents eucalyptol and +¦-terpineol were found to inhibit microbe growths ...201121830186
identification and partial purification of pollen allergens from artemisia princeps.the pollen of artemisia has been considered as the main late summer-autumn allergen source in this country. to identify its allergenic components, artemisia princeps pollen extracts were separated by 10% sodium dodecylsulfate polyacrylamide gel electrophoresis (sds-page), and transferred to nitrocellulose membrane, where ige binding components were detected by the reaction with sera of twenty artemisia-allergic patients and 125i-anti-human ige, sixteen components in the molecular range of 10,000 ...19892626839
dose-response study of sajabalssuk ethanol extract from artemisia princeps pampanini on blood glucose in subjects with impaired fasting glucose or mild type 2 diabetes.previously we reported that an ethanol extract from artemisia princeps pampanini lowered blood glucose in db/db mice. here we report a preliminary study in which the blood glucose-lowering effects of two different doses of sajabalssuk ethanol extract (sbe), containing eupatilin and jaseocidin, were examined in hyperglycemic subjects with fasting blood glucose (fbg) levels of 100-150 mg/dl. subjects were randomized into four groups: negative control (2,000 mg of lactose /day), positive control (1 ...201021138376
antibacterial and antifungal activities of otanthus maritimus (l.) hoffmanns. & link essential oil from sicily.the chemical composition of the essential oil obtained from the flowers of otanthus maritimus l., a perennial plant growing wild in maritime sands in the mediterranean region, was investigated by gc and gc-ms analyses. totally 66 were identified. the oil was dominated by the high content of monoterpene compounds, especially oxygenated monoterpenes which accounted for 73.1%. the most abundant components were yomogi alcohol (20.8%), camphor (15.8%), artemisyl acetate (15.3%) and artemisia alcohol ...201323126552
eupatilin, a dietary flavonoid, induces g2/m cell cycle arrest in human endometrial cancer cells.this study is the first to investigate the antiproliferative effect of eupatilin in human endometrial cancer cells. eupatilin, a naturally occurring flavonoid isolated from artemisia princeps, has anti-inflammatory, anti-oxidative, and anti-tumor activities. in the present study, we investigated the potential effect of eupatilin on cell growth and its molecular mechanism of action in human endometrial cancer cells. eupatilin was more potent than cisplatin in inhibiting cell viability in the huma ...201121554918
anti-obesity and anti-diabetic effects of ethanol extract of artemisia princeps in c57bl/6 mice fed a high-fat diet.artemisia princeps is commonly used as a food ingredient and in traditional asian medicine. in this study, we examined the effects of long-term administration of an ethanol extract of a. princeps (ape) on body weight, white adipose tissue, blood glucose, insulin, plasma and hepatic lipids, and adipocytokines in c57bl/6 mice fed a high-fat diet. daily feeding of a 1% ape diet for 14 weeks normalized elevated body weight, white adipose tissue, and plasma glucose and insulin levels, and delayed imp ...201121773585
multidimensional effects of biologically synthesized silver nanoparticles in helicobacter pylori, helicobacter felis, and human lung (l132) and lung carcinoma a549 cells.silver nanoparticles (agnps) are prominent group of nanomaterials and are recognized for their diverse applications in various health sectors. this study aimed to synthesize the agnps using the leaf extract of artemisia princeps as a bio-reductant. furthermore, we evaluated the multidimensional effect of the biologically synthesized agnps in helicobacter pylori, helicobacter felis, and human lung (l132) and lung carcinoma (a549) cells. uv-visible (uv-vis) spectroscopy confirmed the synthesis of ...201525852332
yomogin, an inhibitor of nitric oxide production in lps-activated macrophages.in activated macrophages the inducible form of nitric oxide synthase (i-nos) generates high amounts of toxic mediator, nitric oxide (no) which contributes to the circulatory failure associated with septic shock. a sesquiterpene lactone compound (yomogin) isolated from medicinal plant artemisia princeps pampan inhibited the production of no in lps-activated raw 264.7 cells by suppressing i-nos enzyme expression. thus, yomogin may be a useful candidate for the development of new drugs to treat end ...19989875481
[studies on the crude drugs used for the folk medicine described in "mimi-bukuro"]."mimi-bukuro" is a book written by moriyasu negishi in the edo period. m. negishi (1737-1815) was a magistrate in the town of edo. he was very much interested in listening and recording many kinds of stories, which were told by the various kinds of people, such as public officers, samurais, merchants, doctors, etc. among the stories of this book, some stories were found concerning folk medicine, medicinal substance and charms. in this report, i studied the medicines which were used in these stor ...199511613523
allohumibacter endophyticus gen. nov., sp. nov., isolated from the root of wild artemisia princeps (mugwort).a novel actinobacterium designated strain mwe-a11t was isolated from the root of wild artemisia princeps (mugwort). the isolate was aerobic, gram-stain-positive and short rod-shaped, and the colonies were yellow and circular with entire margin. strain mwe-a11t grew at 15-37 °c and ph 6.0-8.0. the predominant isoprenoid quinones were mk-11 and mk-10. the predominant fatty acids were anteiso-c15:0 and iso-c16:0, and the dna g+c content was 68.8 mol%. the main polar lipids were diphosphatidylglycer ...201626842896
purification and chemical properties of anti-complementary polysaccharide from the leaves of artemisia princeps. 20144034728
design, synthesis, and antiviral activity of novel rutin derivatives containing 1, 4-pentadien-3-one moiety.rutin (compound 5) and some compounds (compounds 1-4 and 6) were isolated from artemisia princeps pamp (a. princeps pamp.) and a series of novel rutin derivatives containing 1,4-pentadien-3-one moiety were designed and synthesized. the target compounds were characterized by proton nuclear magnetic resonance spectroscopy ((1)h nmr), carbon nuclear magnetic resonance spectroscopy ((13)c nmr), and esi-ms. bioassay results indicated that some of the compounds showed good to excellent antiviral activ ...201525618020
fermented rice bran prevents atopic dermatitis in dncb-treated nc/nga mice.the fermentation of natural plants has a favorable effect on the functional and biological activities of living systems. these include anti-oxidative, anti-inflammatory, and anti-platelet aggregation activities. this is attributed to the chemical conversion of the parent plants to functional constituents, which show more potent biological activity. in our study, rice bran along with oriental medicinal plants (angelicae gigantis, cnidium officinale, artemisia princeps, and camellia sinensis) was ...201627323667
volatile oil constituents of different parts of artemisia chamaemelifolia and the composition and antibacterial activity of the aerial parts of a. turcomanica from iran.the essential oils obtained by hydrodistillation from the aerial parts, stem, leaf and flower of artemisia chamaemelifolia vill. and the aerial parts of a. turcomanica gand. were analyzed by gc and gc/ms. thirty-one compounds representing 96.6%, 94.6%, 93.2% and 91.0% of the oil were identified in the aerial parts, stem, leaf and flower oils of a. chamaemelifolia. menthyl acetate (26.5%, 22.0%, 20.5% and 20.5%) and (z)-nerolidol (20.8%, 26.3%, 14.7% and 18.1%) were the main constituents in the a ...201223285821
effects of artemisia princeps supplementation on bone metabolism in ovariectomized rats.the aim of this study was to investigate the effects of artemisia princeps (ap) extract on bone metabolism and its potential role in the prevention of osteoporosis in ovariectomized rats. twenty-six female sprague-dawley rats were divided into five groups and treated as follows: sham-operated control group (sham); ovariectomized control group (ovx), ovariectomized group treated by gavage with 10 mg/kg/day alendronate (alen); ovariectomized group treated by gavage with 100 mg/kg/day artemisia pri ...201627102792
unexpected irregular monoterpene "yomogi alcohol" in the volatiles of the lathyrus l. species (leguminosae) of cyprus.lathyrus species including l. ochrus and l. sativus are known for their food, feed and horticultural uses. despite their widespread uses and cultivation, there is limited information on their chemistry. previously, only the essential oil composition of l. rotundifolius, l. vernus and volatiles of l. odoratus have been reported. in the present research, volatiles of seven lathyrus l. species, namely, l. aphaca, l. ochrus, l. cicera, l. sativus, l. gorgonei, l. saxatilis and l. blepharicarpos var. ...201626876676
evaluation of nutritional and economic feed values of spent coffee grounds and artemisia princeps residues as a ruminant feed using in vitro ruminal fermentation.much research on animal feed has focused on finding alternative feed ingredients that can replace conventional ones (e.g., grains and beans) to reduce feed costs. the objective of this study was to evaluate the economic, as well as nutritional value of spent coffee grounds (scg) and japanese mugwort (artemisia princeps) residues (apr) as alternative feed ingredients for ruminants. we also investigated whether pre-fermentation using lactobacillus spp. was a feasible way to increase the feed value ...201526528409
artemisia princeps inhibits biofilm formation and virulence-factor expression of antibiotic-resistant bacteria.in this study, we used ethanol extract of a. princeps and investigated its antibacterial effects against mrsa. ethanol extract of a. princeps significantly inhibited mrsa growth and organic acid production during glucose metabolism at concentrations greater than 1 mg/ml (p < 0.05). mrsa biofilm formation was observed using scanning electron microscopy (sem) and safranin staining. a. princeps extract was found to inhibit mrsa biofilm formation at concentrations higher than 2 mg/ml significantly ( ...201526247012
comparative evaluation of antioxidant and insecticidal properties of essential oils from five moroccan aromatic herbs.this study describes the antioxidant and insecticidal activities of essential oils (eos) of mentha suaveolens subsp. timija, thymus satureioides, achillea ageratum, cotula cinerea and salvia officinalis widely used in morocco as flavorings, food additives and preservatives. sixty seven components were identified accounting for more than 95.0 % of the total oils. m. suaveolens subsp. timija oil had as main components menthone and pulegone. a. ageratum oil was particularly rich in artemisyl acetat ...201525829614
long-term treatment with oriental medicinal herb artemisia princeps alters neuroplasticity in a rat model of ovarian hormone deficiency.artemisia princeps (ap) is a flowering perennial used as a traditional medicine and dietary supplement across east asia. no study has yet assessed its effects on synaptic plasticity in hippocampus and much less in a model of ovarian hormone deficiency. we examined the influence of chronic oral ap ethanol extract treatment in ovariectomized rats on the induction of long-term depression in a representative synapse (ca3-ca1) of the hippocampus. ovariectomized rats demonstrated lower trabecular mean ...201525792871
chemopreventive effects of standardized ethanol extract from the aerial parts of artemisia princeps pampanini cv. sajabal via nf-κb inactivation on colitis-associated colon tumorigenesis in mice.chronic inflammation is an underlying risk factor of colon cancer, and nf-κb plays a critical role in the development of inflammation-associated colon cancer in an aom/dss mouse model. the aim of this study was to determine whether the standardized ethanol extract obtained from the aerial parts of artemisia princeps pampanini cv. sajabal (eapp) is effective at preventing inflammation-associated colon cancer, and if so, to identify the signaling pathways involved. in the present study, protective ...201525449198
goat meat does not cause increased blood pressure.while there are persistent rumors that the consumption of goat meat dishes increases blood pressure, there is no scientific evidence to support this. two experiments were conducted to clarify whether or not blood pressure increases in conjunction with the consumption of goat meat dishes. in experiment 1, 24 dahl/iwai rats (15 weeks old, body weight 309.3±11.1 g) were evenly separated into 4 groups. the control group (cp) was fed a diet containing 20% chicken and 0.3% salt on a dry matter basis. ...201425049932
jaceosidin, a natural flavone, promotes angiogenesis via activation of vegfr2/fak/pi3k/akt/nf-κb signaling pathways in endothelial cells.angiogenesis, the growth of new blood vessels from pre-existing vasculature, plays an important role in physiological and pathological processes such as embryonic development wound healing and revascularization of tissues after exposure to ischemia. we investigated the effects of jaceosidin, a main constituent of medicinal herbs of the genus artemisia, on angiogenesis and signaling pathways in endothelial cells. jaceosidin stimulated proliferation, migration and tubulogenesis of ecs as well as e ...201424939823
anticoagulant and antiplatelet activities of artemisia princeps pampanini and its bioactive components.artemisia princeps pampanini (ap) has been used as a traditional medicine in korea, china and japan and reported to exhibit various beneficial biological effects including anti-inflammatory, antioxidant, anti-atherogenic and lipid lowering activities; however, its antiplatelet and anticoagulant properties have not been studied. in the present study, we evaluated the effects of an ethanol extract of artemisia princeps pampanini (eap) and its major flavonoids, eupatilin and jaceosidin, on platelet ...201324471130
antioxidant and anticancer activity of artemisia princeps var. orientalis extract in hepg2 and hep3b hepatocellular carcinoma cells.the aim of the present study was to investigate antioxidant and the anticancerigen activity of a methanol extract from artemisia princeps var. orientalis (apme), a well-known traditional herbal medicine in asia, in hepatocellular cancer cells.201324255577
evaluation of the antioxidant effect of ganghwayakssuk (artemisia princeps pamp.) extract alone and in combination with ascorbic acid in raw chicken patties.we investigated the inhibition of lipid oxidation of raw chicken patties by the antioxidants ascorbic acid (aa), ganghwayakssuk extracts (ge), and their combination (aa + ge). all antioxidant combinations were effective at delaying lipid oxidation compared with the control or aa. a combination of aa + ge (0.05% aa + 0.2% ge) was the most effective for delaying lipid oxidation (tba reactive substances, conjugated dienes, and peroxide formation). the color values of all samples were significantly ...201324235235
determination of five active compounds in artemisia princeps and a. capillaris based on uplc-dad and discrimination of two species with multivariate analysis.five active compounds, chlorogenic acid, 3,5-di-o-caffeoylquinic acid, 4,5-di-o-caffeoylquinic acid, jaceosidin, and eupatilin, in artemisia princeps (compositae) were simultaneously determined by ultra-performance liquid chromatography connected to diode array detector. the morphological resemblance between a. princeps and a. capillaris makes it difficult to properly identify species properly. it occasionally leads to misuse or misapplication in korean traditional medicine. in the study, the di ...201423835834
eupafolin enhances trail-mediated apoptosis through cathepsin s-induced down-regulation of mcl-1 expression and ampk-mediated bim up-regulation in renal carcinoma caki cells.eupafolin, a flavone found in artemisia princeps, has been reported for its anti-tumor activity in several cancer cells. in this study, we examined whether eupafolin could sensitize trail-mediated apoptosis in human renal carcinoma caki cells. we found that eupafolin alone and trail alone had no effect on apoptosis. however, combined treatment with eupafolin and trail markedly induced apoptosis in human renal carcinoma (caki) cells, glioma cells (u251mg), and prostate cancer cells (du145), but n ...201627582546
in vitro and in vivo immunostimulatory effects of hot water extracts from the leaves of artemisia princeps pampanini cv. sajabal.artemisia princeps pampanini (asteraceae) is used as a traditional medicine to immune function-related diseases, such as dysmenorrhea, inflammation, cancer, and ulcers.201323810843
jaceosidin, isolated from dietary mugwort (artemisia princeps), induces g2/m cell cycle arrest by inactivating cdc25c-cdc2 via atm-chk1/2 activation.jaceosidin, a flavonoid derived from artemisia princeps (japanese mugwort), has been shown to inhibit the growth of several human cancer cells, however, the exact mechanism for the cytotoxic effect of jaceosidin is not completely understood. in this study, we investigated the molecular mechanism involved in the antiproliferative effect of jaceosidin in human endometrial cancer cells. we demonstrated that jaceosidin is a more potent inhibitor of cell growth than cisplatin in human endometrial can ...201323274058
artemisia leaf extract induces apoptosis in human endometriotic cells through regulation of the p38 and nfκb pathways.artemisia leaves have long been used for the treatment of gynecological disorders, including infertility and dysmenorrhea, which can be commonly caused by endometriosis. in the present study, we investigated the effect of artemisia princeps extract (ape) on the cell growth and apoptosis of human endometriotic cells.201323228915
effect of dietary supplementation of lactobacillus-fermented artemisia princeps on growth performance, meat lipid peroxidation, and intestinal microflora in hy-line brown male chickens.the objective of this experiment was to investigate the effect of dietary supplementation of lactobacillus-fermented artemisia princeps (lfa) on growth performance, meat lipid peroxidation, and intestinal microflora in hy-line brown male chickens. a total of six hundred twenty-four 1-d-old hy-line brown male chicks were randomly allotted to 3 dietary treatments with 4 replicated pens consisting of 52 chicks. the control diet was formulated to be adequate in energy and nutrients. two additional d ...201223091141
[bioaccumulation of heavy metals by the dominant plants growing in huayuan manganese and lead/zinc mineland, xiangxi].heavy metal pollution is a major environmental problem of mine wasteland. finding out the tolerant plants, which can adapt to the local climate and the soil conditions, is the premise of vegetation restoration. an extensive vegetation survey and sampling were conducted in huayuan mn and pb/zn mineland, 76 species belonging to 69 genera and 39 families were recorded. the main dominant species and their associated soils were determined for heavy metal concentrations. the results showed that soil p ...201222946193
the memory-ameliorating effects of artemisia princeps var. orientalis against cholinergic dysfunction in mice.artemisia princeps var. orientalis (compositae) is widely distributed in china, japan and korea and is known to have anti-inflammatory and anti-oxidative activities. the ethyl acetate fraction of ethanolic extract of a. princeps var. orientalis (aea) was found to inhibit acetylcholinesterase activity in a dose-dependent manner in vitro (ic(50) value: 541.4 ± 67.5 μg/ml). therefore, we investigated the effects of aea on scopolamine-induced learning and memory impairment using the passive avoidanc ...201222928830
development of monacolin k-enriched ganghwayakssuk (artemisia princeps pamp.) by fermentation with monascus pilosus.monacolin k-enriched ganghwayakssuk (artemisia princeps pamp.) was developed by fermentation with monascus sp. among the 15 monascus spp. isolated previously from monascus fermentation products, monascus pilosus kmu108 produced 2,219 mg/kg of monacolin k during ganghwayakssuk fermentation with no detectable citrinin. the optimum concentrations of ganghwayakssuk and glucose determined from the response surface methodology (rsm) design were 2.2% and 3.8%, respectively. by applying these conditions ...201222580317
standardized flavonoid-rich fraction of artemisia princeps pampanini cv. sajabal induces apoptosis via mitochondrial pathway in human cervical cancer hela cells.artemisia princeps pampanini is widely used in eastern traditional medicine for the treatment of circulatory disorders, such as, dysmenorrhea, hematuria, hemorrhoids, and inflammation, and is also used to treat chronic conditions, such as, cancers, ulcers, and digestive disorders.201222449440
essential oil composition and antimicrobial activity of wild and cultivated moroccan achillea ageratum l.: a rare and threatened medicinal species.the essential oils of leaves and flowers of the wild and cultivated moroccan achillea ageratum l., a rare and threatened medicinal species, were examined by gc/ms, and their chemical compositions were compared. at least nine components were identified in both wild and cultivated a. ageratum oils, representing more than 95% of the oils. artemisyl acetate (62.34-78.79%), yomogi alcohol (4.89-12.40%), santolina alcohol (4.86-11.77%), and artemisia alcohol (3.36-7.04%) were the major compounds. terp ...201222422527
a new species of the genus aulacorthum (hemiptera: aphididae) from the korean peninsula and its discrimination from a closely-related species using morphological and molecular characters.aulacorthum sp. collected on artemisia princeps and artemisia stolonifera (asteraceae) in the korean peninsula was compared with the eight aulacorthum species using molecular and morphological characters. in the sequence analysis, the genetic divergences of two mitochondrial genes, coi and cytb, between aulacorthum sp. and the congeneric species were higher than those among the congeneric species. in the morphometric analysis, principal components analysis using 13 morphological characters revea ...201121466349
cytotoxic components of artemisia princeps. 19979270388
sulfated polysaccharide from the leaves of artemisia princeps activates heparin cofactor ii independently of the lys173 and arg189 residues of heparin cofactor ii.a sulfated polysaccharide (afe-hcd) purified from the leaves of artemisia princeps pamp selectively accelerated the rate of thrombin inhibition by heparin cofactor ii (hcii). by using plasma derived hcii and bacterial expressed recombinant hcii molecules, the interaction between each hcii molecule and afe-hcd was analyzed. afe-hcd accelerated thrombin inhibition by plasma derived hcii or bacterial expressed wild type hcii to the same extent (ic50: 0.056 micrograms/ml for plasma derived hcii and ...19979253805
[history of the nippon shinyaku institute for botanical research].soon after its foundation in 1919, nippon shinyaku co., ltd began to develop the domestic production of santonin, an anthelmintic agent, which, until then, had been totally imported from russia. in 1927, artemisia maritima ssp. monogyna was introduced from europe and confirmed to contain santonin. this european aster plant was named mibu-yomogi after the place name of the headquarters of nippon shinyaku. in 1934, yamashina experimental farm was founded to breed mibu-yomogi cultivars of high qual ...201121372535
combined effects between temporal heterogeneity of water supply, nutrient level, and population density on biomass of four broadly distributed herbaceous species.temporal heterogeneity of water supply affects grassland community productivity and it can interact with nutrient level and intraspecific competition. to understand community responses, the responses of individual species to water heterogeneity must be evaluated while considering the interactions of this heterogeneity with nutrient levels and population density. we compared responses of four herbaceous species grown in monocultures to various combinations of water heterogeneity, nutrient level, ...201221327692
allelopathic effects of water extracts ofartemisia princeps var.orientalis on selected plant species.the allelopathic effects of wormwood plants (artemisia princeps var.orientalis) and their possible phytotoxicity on receptor species were investigated. the aqueous extracts of mature leaf, stem, and root of wormwood plants caused significant inhibition in germination and decreased seedling elongation of receptor plants, whereas germination of some species was not inhibited by extracts of stems and roots. dry weight growth was slightly increased at lower concentrations of the extract, whereas it ...199224254631
volatile constituents of artemisia vestita oil1.the essential oil of artemisia vestita (compositae) was investigated by glc, nmr, and mass spectrometry. main constituents are alpha-, beta-, gamma-himachalene, caryophyllene, germacrene d, himachalol, allohimachalol, alpha-, gamma-atlantone, 1,8-cineole, yomogi alcohol, artemisia, and santolina alcohol and their acetates, and the thujones and thujanols. the characteristic oder of the oil is determined by the freshly smelling, 1, 8-cineole and thujone, and by the woody and sweet note of himachal ...198717268966
relevance of the directionality of skin elasticity to aging and sagging of the face.forces acting in facial skin have been suggested to show directionality. non-invasive methods of measuring this directionality may thus provide information related to aging processes. the reviscometer(®) rvm600 device is capable of measuring directionality of forces on the skin. this device has not been used previously in a published study to evaluate changes in directionality of forces on facial skin with aging.201121226877
artemisia princeps extract promoted glucose uptake in cultured l6 muscle cells via glucose transporter 4 translocation.artemisia princeps is a familiar plant as a food substance and medicinal herb. in this study, we evaluated the effects of an ethanol extract of a. princeps (ape) on glucose uptake in differentiated l6 muscle cells. treatment with ape elevated deoxyglucose uptake, and translocation of the insulin-responsive glucose transporter (glut4) to the plasma membrane in l6 myotubes occurred. the pi3k inhibitor ly294002 attenuated glucose uptake induced by ape. phosphorylation of the ser(473) residue of akt ...201020944421
the anti-inflammatory effects and mechanisms of eupafolin in lipopolysaccharide-induced inflammatory responses in raw264.7 macrophages.eupafolin is a flavone isolated from artemisia princeps pampanini (family asteraceae). the aim of this study was to examine the anti-inflammatory effects of eupafolin in lipopolysaccharide (lps)-treated raw264.7 macrophages and lps-induced mouse skin and lung inflammation models and to identify the mechanism underlying these effects. eupafolin decreased the lps-induced release of inflammatory mediators (inos, cox-2 and no) and proinflammatory cytokines (il-6 and tnf-α) from the raw264.7 macropha ...201627414646
the combination of artemisia princeps pamp, leonurus japonicas houtt, and gardenia jasminoides ellis fruit attenuates the exacerbation of energy, lipid, and glucose by increasing hepatic pgc-1α expression in estrogen-deficient rats.artemisia princeps pamp (app), leonurus japonicas houtt (ljh), and gardenia jasminoides ellis fruit (gje) have been traditionally used in east asia to treat women's diseases related to reproductive system. they may attenuate the deterioration of energy, lipid, glucose and bone metabolism by estrogen deficiency. the present study explored the combination of app, ljh, and gje to overcome the symptoms of estrogen deficiency and the mechanism was explored.201627216600
antioxidant action of ganghwayakssuk (artemisia princeps pamp.) in combination with ascorbic acid to increase the shelf life in raw and deep fried chicken nuggets.raw and deep fried chicken nuggets containing various levels of ganghwayakssuk ethanolic extract (ge) in combination with ascorbic acid (aa) were evaluated for shelf-life during refrigerated storage (4°c). the ph and color (lightness, redness, and yellowness) values of raw and deep fried samples were significantly affected by the addition of ge (p<0.05). all antioxidant combinations except for aa+ge 0.01 were effective at delaying lipid oxidation (cd, pov, and tbars) when compared to the control ...201323797017
revised structure of yomogi alcohol a from artemisia feddei lév. et van. 19705412312
positional distribution of fatty acids in galactolipids of artemisia princeps leaves. 19676030374
sesquiterpenoid lactones of artemisia species. i. artemisia princeps pamp. 19665917440
phytohormones in japanese mugwort gall induction by a gall-inducing gall midge.a variety of insect species induce galls on host plants. liquid chromatographic/tandem mass spectrometric analyses showed that a gall midge (rhopalomyia yomogicola) that induces galls on artemisia princeps contained high levels of indole-3-acetic acid and cytokinins. the gall midge larvae also synthesized indole-3-acetic acid from tryptophan. close observation of gall tissue sections indicated that the larval chamber was surrounded by layers of cells having secondary cell walls with extensive li ...201324018692
nocardioides endophyticus sp. nov. and nocardioides conyzicola sp. nov., isolated from herbaceous plant roots.two gram-stain-positive, non-motile, non-spore-forming, rod-shaped actinobacterial strains were isolated from the surface-sterilized roots of mugwort (artemisia princeps) and horse-weed (conyza canadensis), and subjected to taxonomic characterization. 16s rrna gene sequence analysis indicated that the isolates, designated mwe 3-5(t) and hwe 2-02(t), should be placed in the genus nocardioides of the family nocardioidaceae. the strains were closely related to nocardioides hankookensis ds-30(t), wh ...201323990649
[pollinosis. 3. ezo-yomogi (artemisia montana) pollinosis in sapporo, hokkaido, japan]. 19695365966
characterization of nutritional composition, antioxidative capacity, and sensory attributes of seomae mugwort, a native korean variety of artemisia argyi h. lév. & vaniot.few studies have investigated seomae mugwort (a korean native mugwort variety of artemisia argyi h. lév. & vaniot), exclusively cultivated in the southern korean peninsula, and the possibility of its use as a food resource. in the present study, we compared the nutritional and chemical properties as well as sensory attributes of seomae mugwort and the commonly consumed species artemisia princeps pamp. in comparison with a. princeps, seomae mugwort had higher contents of polyunsaturated fatty aci ...201526550520
massive elimination of multinucleated osteoclasts by eupatilin is due to dual inhibition of transcription and cytoskeletal rearrangement.osteoporosis is an aging-associated disease requiring better therapeutic modality. eupatilin is a major flavonoid from artemisia plants such as artemisia princeps and artemisia argyi which has been reported to possess various beneficial biological effects including anti-inflammation, anti-tumor, anti-cancer, anti-allergy, and anti-oxidation activity. complete blockade of rank-dependent osteoclastogenesis was accomplished upon stimulation prior to the receptor activator of nuclear factor κb (rank ...201528377971
multiplex pcr method to discriminate artemisia iwayomogi from other artemisia plants.some plants in the genus artemisia have been used for medicinal purposes. among them, artemisia iwayomogi, commonly referred to as "haninjin," is one of the major medicinal materials used in traditional korean medicine. by contrast, artemisia capillaris and both artemisia argyi and artemisia princeps, referred to as "injinho" and "aeyup," respectively, are used to treat diseases different from those for which "haninjin" is prescribed. therefore, the development of a reliable method to differenti ...201222419495
volatile components of the essential oil of artemisia montana and their sedative effects.the sedative effects of volatile components in the essential oil of artemisia montana ("yomogi") were investigated and measured using gas chromatography-mass spectrometry (gc-ms). major components identified included 1,8-cineol, camphor, borneol, α-piperitone, and caryophyllene oxide. among them, 1,8-cineol exhibited the highest flavor dilution (fd) value in an aroma extract dilution analysis (aeda), followed by borneol, o-cymene, β-thujone, and bornyl acetate. the sedative effects of yomogi oil ...201728381767
anti-inflammatory effects of artemisia princeps in antigen-stimulated t cells and regulatory t cells.the aim was to investigate the anti-inflammatory effects of artemisia princeps extract on the activity of anti-cd3/cd28-stimulated cd4(+)cd25(-) t cells and antigen-expanded regulatory t cells.200919703348
inhibitory effect of eupatilin and jaceosidin isolated from artemisia princeps in ige-induced hypersensitivity.to understand the antiallergic effect of artemisia princeps (ap), which has been found to show inhibitory activity against degranulation and a passive cutaneous anaphylaxis (pca) reaction, eupatilin and jaceosidin, as the active components, were isolated by degranulation-inhibitory activity-guided fractionation, with their antiallergic activity investigated. these isolated components potently inhibited the release of beta-hexosaminidase from rbl-2h3 cells induced by the ige-antigen complex, with ...200717996677
antioxidant activity of various teas against free radicals and ldl oxidation.tea is a widely consumed beverage throughout the world. we assessed the antioxidant activity of six teas, including the aqueous extracts of green tea and oolong tea (camellia sinensis), tochu (eucommia ulmoides), gymnema sylvestre, japanese mugwort (artemisia princeps), and barley (hordeum vulgare), against 1,1-diphenyl-2-picrylhydrazyl (dpph) radicals and ldl oxidation, and examined the association of ldl oxidizability with the plasma catechin levels in 10 healthy volunteers with a single dose ...200516296404
repellent and insecticidal activities of essential oils from artemisia princeps and cinnamomum camphora and their effect on seed germination of wheat and broad bean.repellent and insecticidal activities of essential oils extracted from leaves of artemisia princeps pamp and seeds of cinnamomum camphora (l.) presl. against storage pests sitophillus oryzae l. and bruchus rugimanus bohem were investigated. results showed that the two individual oils displayed good, but their mixture (1:1) exhibited much better repellent activities at concentrations from 250 to 1000 microg g(-1) and insecticidal actions at concentrations 1000 microg g(-1) against the test beetle ...200616230008
chemical composition and antimicrobial activity of the essential oil of artemisia lavandulaefolia.the chemical components of the essential oil obtained from artemisia lavandulaefolia dc. were analyzed by gc-ms. ninety-nine compounds accounting for 94.9 % of the essential oil were identified. the major compounds in the essential oil were beta-caryophyllene (16.1 %), cis-chrysanthenol (7.0 %), 1,8-cineole (5.6 %), borneol (5.3 %), trans-beta-farnesene (5.1 %), camphor (4.9 %), yomogi alcohol (4.5 %), alpha-terpineol (3.9 %), and alpha-humulene oxide (3.3 %). the essential oil and some of its m ...200515971134
mycorrhizal colonization and plant growth affected by aqueous extract of artemisia princeps var. orientalis and two phenolic compounds.the effects of an aqueous extract of artemisia princeps var. orientalis and two phenolic compounds on mycorrhizal colonization and plant growth have been investigated. greenhouse studies showed that the inhibitory effect of the extract on mycorrhizal colonization and plant growth increased in proportion to the concentration of the extract. when the mycorrhizal test plants were treated with an increasing concentration of phenolic compounds, the mycorrhizal colonization in roots of the test plant ...200211925073
[the advantages and disadvantages of artemisia princeps and a. montana].in japan, moxa is made from artemisia princeps and a. montana p. which are plants of the composiae family. evaluations of the superiority or inferiority of these raw materials for moxa have been confusing. the judgement of superiority or inferiority is roughly based on the strenght of the fragrance and somewhat of down. when i investigated 14 kinds of documents from the edo period to the showa period, 10 of the documents gave good evaluations for artemisia princeps. on the other hand the remaini ...200011640207
volatile chemicals identified in extracts from leaves of japanese mugwort (artemisia princeps pamp.).extracts from leaves of japanese mugwort (artemisia princeps pamp.) were obtained using two methods: steam distillation under reduced pressure followed by dichloromethane extraction (drp) and simultaneous purging and extraction (spse). a total of 192 volatile chemicals were identified in the extracts obtained by both methods using gas chromatography (gc) and gas chromatography-mass spectrometry (gc-ms). they included 47 monoterpenoids (oxygenated monoterpenes), 26 aromatic compounds, 19 aliphati ...200010956134
yomogin inhibits the degranulation of mast cells and the production of the nitric oxide in activated raw 264.7 cells.yomogin (1), an eudesmane sesquiterpene isolated from artemisia princeps, was tested for the effects on the degranulation process of cultured mast cells and on the nitric oxide production in lps-activated murine macrophages. it demonstrated a significant inhibition on the release of beta-hexosaminidase from the cultured rbl-2h3 cells in a dose-dependent manner (ic50 value, 50 microm) and also exhibited a potent inhibition on the nitric oxide production from the activated raw264.7 cells (ic50 val ...200010763594
[simejigahara, a place noted for moxa].shimejigahara is a place-name often used in old waka (japanese poems). it was reputed in the past to be a site rich in the plants moxa and mugwort. a study of this placed carried out. shimejigahara, as mentioned in the literature of the heian to kamakura eras, seems to have been located at the site of the current tochigi city. during the edo era, however, senjogahara in nikko came to be referred to as shimejigahara. in addition, some other places in what is now called utsunomiya city, on ibuki m ...199611619106
influence ofartemisia princeps var.orientalis components on callus induction and growth.an in vitro study was performed to determine the potential application of tissue culture in determining allelopathic potentialof artemisia princeps var.orientalis (wormwood). aqueous extracts and volatile substances ofa. princeps var.orientalis were tested to determine their effects on callus induction and growth of several tested species. extracts of 5%a. princeps var.orientalis caused some reduction in concentration, induction, and growth of callus, although they looked normal, whereas the exp ...199224254218
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