| observations on the relationship in chickens between the virulence of some avian influenza viruses and their pathogenicity for various organs. | comparative histological and immunocytochemical studies were conducted on formalin-fixed tissues from chickens infected with avian influenza viruses of varying virulence. results showed a distinct pattern of disease that depended on the virulence of the virus and the susceptibility of the birds. at 3 days post-intranasal inoculation with a highly virulent h7n7 virus, all 6-to-8-week-old specific-pathogen-free (spf) birds were affected, and all developed pancreatic necrosis and encephalitis assoc ... | 1995 | 8561728 |