| iamia majanohamensis gen. nov., sp. nov., an actinobacterium isolated from sea cucumber holothuria edulis, and proposal of iamiaceae fam. nov. | a novel, gram-positive bacterial strain, f12(t), was isolated from the abdominal epidermis of a sea cucumber, holothuria edulis, collected from seawater off the coast of japan. according to 16s rrna gene sequence analysis, this strain represents a novel, deep-rooting lineage within the class actinobacteria and clusters with uncultured bacteria and acidimicrobium ferrooxidans. compared to species with validly published names, the highest 16s rrna gene sequence similarity (89.8 %) was to acidimicr ... | 2009 | 19329622 |
| euzebya tangerina gen. nov., sp. nov., a deeply branching marine actinobacterium isolated from the sea cucumber holothuria edulis, and proposal of euzebyaceae fam. nov., euzebyales ord. nov. and nitriliruptoridae subclassis nov. | a tangerine-coloured, gram-positive actinobacterial strain, designated f10(t), was isolated from the abdominal epidermis of a sea cucumber, holothuria edulis, collected in seawater off the coast of japan. a 16s rrna gene sequence analysis indicated that strain f10(t) was a member of the class actinobacteria and was most closely related to nitriliruptor alkaliphilus anl-iso2(t) (87.4 % sequence similarity). phylogenetic analyses showed that strain f10(t) represented a novel, deep-rooted, and dist ... | 2010 | 19915105 |
| structural analysis and anticoagulant activities of the novel sulfated fucan possessing a regular well-defined repeating unit from sea cucumber. | sulfated fucans, the complex polysaccharides, exhibit various biological activities. herein, we purified two fucans from the sea cucumbers holothuria edulis and ludwigothurea grisea. their structures were verified by means of hpgpc, ft-ir, gc-ms and nmr. as a result, a novel structural motif for this type of polymers is reported. the fucans have a unique structure composed of a central core of regular (1→2) and (1→3)-linked tetrasaccharide repeating units. approximately 50% of the units from l. ... | 2015 | 25871288 |
| antioxidant and cytotoxic properties of two sea cucumbers, holothuria edulis lesson and stichopus horrens selenka. | sea cucumbers are marine invertebrates of the phylum of echinodermata that have been used in asian traditional medicine since ancient times. this study was conducted to investigate the antioxidant and cytotoxic properties of aqueous and organic extracts from two sea cucumber species, holothuria edulis lesson (holothuriidae) and stichopus horrens selenka (stichopodidae). antioxidant activities of the extracts were evaluated by dpph· and β-carotene bleaching assays, while mtt and trypan blue exclu ... | 2013 | 23567827 |
| anticancer activity and mediation of apoptosis in human hl-60 leukaemia cells by edible sea cucumber (holothuria edulis) extract. | sea cucumbers have been a dietary delicacy and important ingredient in asian traditional medicinal over many centuries. in this study, edible sea cucumber holothuria edulis was evaluated for its in vitro anticancer potential. an aqueous fraction of the edible sea cucumber (esc-aq) has been shown to deliver a strong cytotoxic effect against the human hl-60 leukaemia cell line. an induction effect of apoptotic body formation in response to esc-aq treatment was confirmed in hl-60 cells stained with ... | 2013 | 23561113 |
| comparison of physicochemical characteristics and anticoagulant activities of polysaccharides from three sea cucumbers. | in order to search for sulfated polysaccharides in different invertebrate connective tissues and to examine their biological activities, we have isolated three types of polysaccharides from the body wall of the three sea cucumbers holothuria edulis, apostichopus japonicas and holothuria nobilis. the physicochemical properties and anticoagulant activities of these polysaccharides were examined and compared. the chemical composition analysis and nuclear magnetic resonance (nmr) analysis indicate t ... | 2013 | 23385300 |