| complete sequence characterization of the genome of the st croix river virus, a new orbivirus isolated from cells of ixodes scapularis. | an orbivirus identified as st croix river virus (scrv) was isolated from cells of ixodes scapularis ticks. electron microscopy showed particles with typical orbivirus morphology. the scrv genome was sequenced completely and compared to previously characterized orbivirus genomes. significant identity scores (21-38%) were detected between proteins encoded by segments s1, s2, s4, s5, s6, s8, s9 and s10 of scrv and those encoded by segments s1, s3, s4, s5, s6, s7, s9 and s10, respectively, of blueto ... | 2001 | 11257184 |
| characterising non-structural protein ns4 of african horse sickness virus. | african horse sickness is a serious equid disease caused by the orbivirus african horse sickness virus (ahsv). the virus has ten double-stranded rna genome segments encoding seven structural and three non-structural proteins. recently, an additional protein was predicted to be encoded by genome segment 9 (seg-9), which also encodes vp6, of most orbiviruses. this has since been confirmed in bluetongue virus and great island virus, and the non-structural protein was named ns4. in this study, in si ... | 2015 | 25915516 |
| investigating the effects of age-related spatial structuring on the transmission of a tick-borne virus in a colonially breeding host. | higher pathogen and parasite transmission is considered a universal cost of colonial breeding due to the physical proximity of colony members. however, this has rarely been tested in natural colonies, which are structured entities, whose members interact with a subset of individuals and differ in their infection histories. we use a population of common guillemots,uria aalge, infected by a tick-borne virus,great island virus, to explore how age-related spatial structuring can influence the infect ... | 2017 | 29299270 |
| genetic characterization of the tick-borne orbiviruses. | the international committee for taxonomy of viruses (ictv) recognizes four species of tick-borne orbiviruses (tbos): chenuda virus, chobar gorge virus, wad medani virus and great island virus (genus orbivirus, family reoviridae). nucleotide (nt) and amino acid (aa) sequence comparisons provide a basis for orbivirus detection and classification, however full genome sequence data were only available for the great island virus species. we report representative genome-sequences for the three other t ... | 2015 | 25928203 |
| [the taxonomy of the baku virus (bakv; reoviridae, orbivirus) isolated from the birds obligate parasites argasidae ticks in azerbaijan, turkmenistan, and uzbekistan]. | the baku virus (bakv) was originally isolated from the ticks ornithodoros capensis neumann, 1901 (acari: argasidae) collected from the seagull (larus argentatus) seating nests on the islands of the baku archipelago, the caspian sea. bakv was assigned to kemerovo group (kemv) (orbivirus, reoviridae). the bakv was frequently isolated from the ticks o. coniceps canestrini, 1980, collected from l. argentatus and tern (sterna hirundo) nests in turkmenia and pigeon (columba livia neglecta) nests in uz ... | 2016 | 24772642 |
| genetic characterization of tribeč virus and kemerovo virus, two tick-transmitted human-pathogenic orbiviruses. | we determined the complete genome sequences of tribeč virus (trbv) and kemerovo virus (kemv), two tick-transmitted orbiviruses that can cause diseases of the central nervous system and that are currently classified into the great island virus serogroup. vp2 proteins of trbv and kemv show very low sequence similarity to the homologous vp4 protein of tick-transmitted great island virus (giv). the new sequence data support previous serological classification of these orbiviruses into the kemerovo s ... | 2011 | 22189211 |
| detection of a fourth orbivirus non-structural protein. | the genus orbivirus includes both insect and tick-borne viruses. the orbivirus genome, composed of 10 segments of dsrna, encodes 7 structural proteins (vp1-vp7) and 3 non-structural proteins (ns1-ns3). an open reading frame (orf) that spans almost the entire length of genome segment-9 (seg-9) encodes vp6 (the viral helicase). however, bioinformatic analysis recently identified an overlapping orf (orfx) in seg-9. we show that orfx encodes a new non-structural protein, identified here as ns4. west ... | 2011 | 22022432 |
| Umatilla virus genome sequencing and phylogenetic analysis: identification of stretch lagoon orbivirus as a new member of the Umatilla virus species. | The genus Orbivirus, family Reoviridae, includes 22 species of viruses with genomes composed of ten segments of linear dsRNA that are transmitted between their vertebrate hosts by insects or ticks, or with no identified vectors. Full-genome sequence data are available for representative isolates of the insect borne mammalian orbiviruses (including bluetongue virus), as well as a tick borne avian orbivirus (Great Island virus). However, no sequence data are as yet available for the mosquito borne ... | 2011 | 21897849 |
| complete sequence of great island virus and comparison with the t2 and outer-capsid proteins of kemerovo, lipovnik and tribec viruses (genus orbivirus, family reoviridae). | the complete nucleotide sequence of great island virus (giv) genome was determined, along with genome segments (seg) 1, 2 and 6 of kemerovo (kemv), lipovnik (lipv) and tribec (trbv) viruses. all four viruses, together with broadhaven virus, are currently classified within the species great island virus and have been isolated from ticks, birds or humans. sequence comparisons showed that seg-4 of giv encoded the outer-capsid protein responsible for cell attachment, although it was approximately ha ... | 2010 | 20739272 |
| tick-borne great island virus: (i) identification of seabird host and evidence for co-feeding and viraemic transmission. | great island virus (giv) is an arbovirus present in the tick ixodes uriae, a common ectoparasite of nesting seabirds. common guillemot (uria aalge) and black-legged kittiwake (rissa tridactyla) are the preferred and most abundant hosts of i. uriae on the isle of may, scotland. as part of a study to understand the epidemiology of giv, the ability of guillemot and kittiwake to support tick-borne transmission of giv was examined. giv was present in ticks feeding in isolated guillemot colonies and g ... | 2006 | 16216136 |
| tick-borne great island virus: (ii) impact of age-related acquired immunity on transmission in a natural seabird host. | tick-borne pathogen transmission is dependent upon tick number per host and the physical and temporal distribution of each feeding stage. age-related acquired immunity to tick and pathogen may also be important but has received less attention. in this study we evaluate which of these parameters has the greatest impact on great island virus (giv) transmission between ixodes uriae ticks and common guillemots (uria aalge). the study system is well suited to investigate age-related effects because t ... | 2006 | 16197591 |
| [molecular-genetic characterization of the okhotskiy virus (okhv) and aniva virus (aniv) (orbivirus, reoviridae) isolated from the ticks ixodes (ceratixodes) uriae white, 1852 in high latitudes of the northern eurasia]. | molecular-genetic characteristics of the okhotskiy virus (okhv) and aniva virus (aniv) were studied (id genbank kf981623-32). these viruses are distributed over the shelf and island areas in the high latitudes in the okhotsk, bering, and barents seas and linked with nesting colonies of alcidae seabirds and their obligatory parasites, the ixodes uriae (ixodidae) ticks. okhv and aniv are observed to be independent species within the limits of the great island virus (giv) group of the orbivirus gen ... | 2016 | 25069281 |
| genetic and biological characterization of muko virus, a new distinct member of the species great island virus (genus orbivirus, family reoviridae), isolated from ixodid ticks in japan. | among the tick-borne orbiviruses (genus orbivirus, family reoviridae), 36 serotypes are currently classified within a single virus species, great island virus. in this study, we report the first characterization of a tick-borne orbivirus isolated from the tick ixodes turdus in japan, which we identified as a new member of the species great island virus. the virus isolate, designated muko virus (muv), replicated and induced cytopathic effects in bhk-21, vero e6, and ccl-141 cells and caused high ... | 2015 | 26350980 |