| the genome phylogeny of domestic cat, red panda and five mustelid species revealed by comparative chromosome painting and g-banding. | genome-wide homology maps among stone marten (martes foina, 2n = 38), domestic cat (felis catus, 2n = 38), american mink (mustela vison, 2n = 30), yellow-throated marten (martes flavigula, 2n = 40), old world badger (meles meles, 2n = 44), ferret badger (melogale moschata, 2n = 38) and red panda (ailurus fulgens, 2n = 36) have been established by cross-species chromosome painting with a complete set of stone marten probes. in total, 18 stone marten autosomal probes reveal 20, 19, 21, 18 and 21 p ... | 2002 | 12067210 |
| molecular phylogeny of arctoids (mammalia: carnivora) with emphasis on phylogenetic and taxonomic positions of the ferret-badgers and skunks. | phylogenetic relationships among the ferret-badger melogale moschata, the skunk mephitis mephitis, and 21 other arctoid carnivorans, representing mustelidae (mustelinae: mustela, martes, gulo; lutrinae: enhydra; melinae: meles), procyonidae (procyon), and ursidae (ursus, melursus), were evaluated through maximum-parsimony phylogenetic analysis of concatenated partial nucleotide sequences of the nuclear recombination-activating gene 1 (rag1) and gene encoding interphotoreceptor retinoid-binding p ... | 2004 | 14745111 |
| detection of a novel and highly divergent coronavirus from asian leopard cats and chinese ferret badgers in southern china. | since an outbreak of severe acute respiratory syndrome (sars) was averted in 2004, many novel coronaviruses have been recognized from different species, including humans. bats have provided the most diverse assemblages of coronaviruses, suggesting that they may be the natural reservoir. continued virological surveillance has proven to be the best way to avert this infectious disease at the source. here we provide the first description of a previously unidentified coronavirus lineage detected fro ... | 2007 | 17459938 |
| canine distemper virus in wild ferret-badgers of taiwan. | canine distemper is an acute or subacute, highly contagious, febrile disease that is caused by canine distemper virus (cdv). two cdv-infected wild taiwan ferret-badgers (melogale moschata subauantiaca) were found in kaohsiung county, southern taiwan, in 2005. each case was confirmed by detecting cdv rna in lung and brain tissues. a suspected third case was detected based on clinical signs and histology. these cases are the first record of wildlife infected by cdv in taiwan. it is believed that d ... | 2008 | 18436676 |
| characterization of a rabies virus isolate from a ferret badger (melogale moschata) with unique molecular differences in glycoprotein antigenic site iii. | rabies virus was isolated from the brain of a chinese ferret badger (melogale moschata) and identified as having an r333q substitution within its glycoprotein antigenic site iii. additionally, compared with vaccine strains and other rabies virus isolates from dogs and ferret badgers in china, the isolate had five other amino acid substitutions in its glycoprotein: p(-17)l in the signal peptide, r88h, l225m, and d422e in the ectoplasmic region, and g478e in the cytoplasmic region. this isolate po ... | 2010 | 20109507 |
| [complete genome sequencing and analyses of rabies viruses isolated from wild animals (chinese ferret-badger) in zhejiang province]. | based on sequencing the full-length genomes of two chinese ferret-badger, we analyzed the properties of rabies viruses genetic variation in molecular level to get information on prevalence and variation of rabies viruses in zhejiang, and to enrich the genome database of rabies viruses street strains isolated from chinese wildlife. | 2009 | 20193207 |
| [sequencing and analysis of complete genome of rabies viruses isolated from chinese ferret-badger and dog in zhejiang province]. | based on sequencing the full-length genomes of four chinese ferret-badger and dog, we analyze the properties of rabies viruses genetic variation in molecular level, get the information about rabies viruses prevalence and variation in zhejiang, and enrich the genome database of rabies viruses street strains isolated from china. rabies viruses in suckling mice were isolated, overlapped fragments were amplified by rt-pcr and full-length genomes were assembled to analyze the nucleotide and deduced p ... | 2010 | 20329558 |
| experimental oral immunization of ferret badgers (melogale moschata) with a recombinant canine adenovirus vaccine cav-2-e3δ-rgp and an attenuated rabies virus srv9. | ferret badgers (melogale moschata) are a major reservoir of rabies virus in southeastern china. oral immunization has been shown to be a practical method for wildlife rabies management in europe and north america. two groups of 20 ferret badgers were given a single oral dose of a recombinant canine adenovirus-rabies vaccine, cav-2-e3δ-rgp, or an experimental attenuated rabies virus vaccine, srv9. at 21 days, all ferret badgers had seroconverted, with serum virus-neutralizing antibodies ranging f ... | 2014 | 24506428 |
| rabies and rabies virus in wildlife in mainland china, 1990-2013. | the number of wildlife rabies and wildlife-associated human and livestock rabies cases has increased in recent years, particularly in the southeast and northeast regions of mainland china. to better understand wildlife rabies and its role in human and livestock rabies, we reviewed what is known about wildlife rabies from the 1990s to 2013 in mainland china. in addition, the genetic diversity and phylogeny of available wildlife-originated rabies viruses (rabvs) were analyzed. several wildlife spe ... | 2014 | 24911887 |
| origin, evolution, and virulence of porcine deltacoronaviruses in the united states. | a novel porcine deltacoronavirus (pdcv) was first discovered in ohio and indiana in february 2014, rapidly spread to other states in the united states and canada, and caused significant economic loss in the swine industry. the origin and virulence of this novel porcine coronavirus are not known. here, we characterized u.s. pdcv isolates and determined their virulence in gnotobiotic and conventional piglets. genome analyses revealed that u.s. pdcv isolates possess unique genetic characteristics a ... | 2015 | 25759498 |
| pathology and molecular detection of rabies virus in ferret badgers associated with a rabies outbreak in taiwan. | until rabies virus (rabv) infection in taiwan ferret badgers (twfb; melogale moschata subaurantiaca) was diagnosed in mid-june 2013, taiwan had been considered rabies free for >50 yr. although rabies has also been reported in ferret badgers in china, the pathologic changes and distribution of viral antigens of ferret badger-associated rabies have not been described. we performed a comprehensive pathologic study and molecular detection of rabies virus in three necropsied rabid twfbs and evaluated ... | 2016 | 26560756 |
| rabies virus infection in ferret badgers (melogale moschata subaurantiaca) in taiwan: a retrospective study. | fifteen ferret badgers (melogale moschata subaurantiaca), collected 2010-13 and stored frozen, were submitted for rabies diagnosis by direct fluorescent antibody test and reverse transcription pcr. we detected seven positive animal samples, including some from 2010, which indicated that the ferret badger population in taiwan had been affected by rabies prior to 2010. | 2015 | 26267459 |
| molecular characterization of cryptically circulating rabies virus from ferret badgers, taiwan. | after the last reported cases of rabies in a human in 1959 and a nonhuman animal in 1961, taiwan was considered free from rabies. however, during 2012-2013, an outbreak occurred among ferret badgers in taiwan. to examine the origin of this virus strain, we sequenced 3 complete genomes and acquired multiple rabies virus (rabv) nucleoprotein and glycoprotein sequences. phylogeographic analyses demonstrated that the rabv affecting the taiwan ferret badgers (rabv-twfb) is a distinct lineage within t ... | 2014 | 24751120 |
| molecular characterization of three ferret badger (melogale moschata) rabies virus isolates from jiangxi province, china. | ferret badger (fb) rabies viruses jx09-17(fb), jx09-18 and jx10-37 were isolated from three different regions in jiangxi province, china, in 2009 and 2010. the complete nucleotide sequence identity between these three isolates was 87-93 %. compared with the other chinese rabies virus isolates and vaccine strains, 101 substitutions (53 in jx10-37, 23 in jx09-17(fb) and 25 in jx09-18) in the five structural proteins were observed, and 47 of these substitutions (27 in jx10-37, 14 in jx09-17(fb) and ... | 2014 | 24643334 |
| complete genome sequence of a rabies virus isolate from a ferret badger (melogale moschata) in jiangxi, china. | the genome of ferret badger rabies virus jx09-17(fb), isolated in jiangxi province, china, in 2009 has been completely sequenced. the genomic length is 11, 923 nucleotides (nt) with an overall organization similar to that of other rabies virus isolates. jx09-17(fb) is closely related to chinese epidemic canine isolates in clade i. | 2013 | 23766399 |
| epidemic and maintenance of rabies in chinese ferret badgers (melogale moschata) indicated by epidemiology and the molecular signatures of rabies viruses. | an epidemic of chinese ferret badger-associated human rabies was investigated in wuyuan county, jiangxi province and rabies viruses isolates from ferret badgers in different districts in jiangxi and zhejiang provinces were sequenced with their nucleotides and amino acids and aligned for epidemiological analysis. the results showed that the human rabies in wuyuan are only associated with ferret badger bites; the rabies virus can be isolated in a high percentage of ferret badgers in the epidemic a ... | 2013 | 23689981 |
| complete genome sequence of a rabies virus isolate from cattle in guangxi, southern china. | a street rabies virus (rv) isolate, gxhxn, was obtained from brain tissue of rabid cattle in the guangxi zhuang autonomous region of china in 2009. gxhxn is the first isolate from cattle in china with its entire genome sequenced and is closely related to bj2011e from horse in beijing, wh11 from donkey in the hubei province, and isolates from dogs in the guangxi and fujian provinces, with homologies of 97.6% to 99.6%. it is more distantly related to isolates from domestic cat, pig, chinese ferret ... | 2013 | 23405368 |
| adaptation of a chinese ferret badger strain of rabies virus to high-titered growth in bhk-21 cells for canine vaccine development. | rabies virus strain jx08-45cc was derived from a chinese isolate (jx08-45) by serial passage in the bhk-21 cell line, reaching a titer of 10(8) tcid(50)/ml. jx08-45cc produced rabies in adult mice but was nonpathogenic in dogs after intramuscular injection. a comparison of the entire genomes of jx08-45 and jx08-45cc led to the identification of 17 nucleotide substitutions, resulting in seven amino acid changes in the mature g and l proteins. the immunogenicity of β-propiolactone-inactivated jx08 ... | 2012 | 22886183 |
| prevalence and genetic characterization of toxoplasma gondii in badgers (melogale moschata) in southern china by pcr-rflp. | toxoplasma gondii is an obligate intracellular apicomplexan parasite which is able to infect almost all warm-blooded animals. there is no information about the prevalence and genetic characterization of t. gondii in badgers (melogale moschata) in china. here, a total of 367 badgers were captured from different cities in jiangxi province, southern china. genomic dna was extracted from brain tissues of each badgers, and 57 (15.45%) of them were positive for t. gondii by semi-nested pcr of the b1 g ... | 2017 | 28434971 |
| [research advances in the porcine deltacoronavirus]. | the deltacoronavirus is a new member of the subfamily coronaviridae of the family coronaviridae. deltacoronaviruses can infect birds and mammals. deltacoronaviruses were detected in early 2007 in asian leopard cats and chinese ferret badgers. in 2014, porcine deltacoronavirus (pdcov) infection spread rapidly in the usa. moreover, cell culture-adapted pdcov has been obtained from infected piglets. animal experiments have confirmed that the isolated pdcov is highly pathogenic and causes severe dia ... | 2016 | 27396171 |
| novel calicivirus from a ferret badger (melogale moschata) in china. | we describe the isolation and complete genome sequence of a new calicivirus, fbcv-jx12, isolated from a ferret badger (melogale moschata). comparison of fbcv-jx12 with other vesiviruses revealed that it shared the highest amino acid sequence identities of 71.6, 60.5, and 59.3% in the nonstructural protein, vp1, and vp2, respectively, with mcv-dl2007 (mink calicivirus). phylogenetic analysis of the whole genomic sequence showed that it clustered most closely with mcv-dl2007 of the genus vesivirus ... | 2015 | 25976558 |
| notes from the field: wildlife rabies on an island free from canine rabies for 52 years--taiwan, 2013. | dog-to-dog transmission of rabies in taiwan was eliminated in 1961; the island was considered canine rabies-free for 52 years. on july 16, 2013, three ferret-badgers (melogale moschata) tested positive for rabies by fluorescent antibody testing at the animal health research institute, council of agriculture of taiwan. this was the first time wild animals other than bats were tested. during 1999-2012, a total of 6,841 clinically healthy dogs and five apparently normal cats from shelters were test ... | 2014 | 24572614 |
| initial pen and field assessment of baits to use in oral rabies vaccination of formosan ferret-badgers in response to the re-emergence of rabies in taiwan. | taiwan had been considered rabies free since 1961, until a newly established wildlife disease surveillance program identified rabies virus transmission within the formosan ferret-badger (melogale moschata subaurantiaca) in 2013. ferret-badgers occur throughout southern china and southeast asia, but their ecological niche is not well described. | 2018 | 29293591 |
| blood lead and zinc levels and their impact on health of free-living small carnivores in taiwan, republic of china. | lead and zinc are recognized as the most widespread trace metals in nature and can, at high levels, compromise the health of wildlife and their habitat. because of their position in a higher trophic level, wild carnivores can be valuable biological indicator species of trace-metal contamination in the environment. we assessed blood lead and zinc concentrations of four small carnivore species native to taiwan, the small indian civet (viverricula indica), the masked palm civet (paguma larvata), th ... | 2020 | 31532734 |
| ferret badger rabies in zhejiang, jiangxi and taiwan, china. | ferret badger (fb, melogale moschata) rabies is an increasing public health threat to humans, with fbs being a major reservoir and vector of rabies in china. based on 152 published nucleotide sequences of the fb rabies virus (rabv) nucleoprotein, phylogenetic analysis revealed them to be clustered into six fb-related lineages, fb-i to fb-vi. the genetic features of members of lineage fb-vi suggest that cross-species transmission occurs between fbs and dogs. here, we describe the phylogenetic rel ... | 2019 | 30417198 |
| modeling the transmission dynamics of rabies for dog, chinese ferret badger and human interactions in zhejiang province, china. | human rabies is one of the major public health problems in china with an average of 1977 cases per year. it is estimated that 95% of these human rabies cases are due to dog bites. in recent years, the number of wildlife-associated human rabies cases has increased, particularly in the southeast and northeast regions of mainland china. chinese ferret badgers (cfbs) are one of the most popular wildlife animals which are distributed mostly in the southeast region of china. human cases caused by rabi ... | 2019 | 30536160 |
| emerging new phylogenetic groups of rabies virus in chinese ferret badgers. | chinese ferret badger (fb)-transmitted rabies is a serious threat to public health in southeast china. although mostly associated with dogs, the rabies virus (rabv) presents genetic diversity and has a significantly wide host range in china. instead of the dog- and wildlife-associated china ii lineage in the past decades, the china i lineage has become the main epidemic group hosted and transmitted by dogs. in this study, four new lineages, including 43 rabvs from fbs, have been classified withi ... | 2018 | 30025563 |
| human exposure to ferret badger rabies in taiwan. | on 17 july 2013, taiwan confirmed multiple cases of the rabies virus (rabv) in the wild taiwan ferret badger (tfb) (melogale moschata) member of the family mustelidae. this study aims at investigating the risk factors for human exposure to rabid tfbs. statistical inference based on pearson correlation showed that there was a strong positive correlation between the total number of positive tfb rabies cases and the number of rabid tfbs involved with human activities in 81 enzootic townships (r = 0 ... | 2018 | 29954098 |
| molecular characteristics of carnivore protoparvovirus 1 with high sequence similarity between wild and domestic carnivores in taiwan. | carnivore protoparvovirus 1 (cppv-1) is a dna virus causing gastrointestinal disease and immunosuppression in various terrestrial carnivores. domestic dogs and cats are considered the primary cppv-1 reservoirs. the habitat overlap of wild carnivores and free-roaming dogs increases the threat of cppv-1 transmission between them. this study explored the cppv-1 distribution among wild carnivores in taiwan through pcr screening and compared the partial capsid protein (vp2) gene sequences from wild a ... | 2021 | 34072499 |