| brocaenols a-c: novel polyketides from a marine derived penicillium brocae. | chemical investigation of a penicillium brocae, obtained from a tissue sample of a fijian zyzyya sp. sponge, yielded two known diketopiperazines and three novel cytotoxic polyketides, brocaenols a-c. the brocaenols contain an unusual enolized oxepine lactone ring system that to the best of our knowledge is unprecedented in the literature. the structures were elucidated by using 2d-nmr methods including an inadequate experiment. the absolute stereochemistry of brocaenol a was established by using ... | 2003 | 12608826 |
| penicillium brocae, a new species associated with the coffee berry borer in chiapas, mexico. | penicillium brocae is a new monoverticillate species isolated from coffee berry borers collected at coffee plantations in mexico near cacahoatán, chiapas, and from borers reared on artificial diets at ecosur laboratory facilities in tapachula, chiapas. phenotypically, it is in penicillium series implicatum, but because it does not conform to known species we have described it as new. its and large subunit rdna were sequenced and compared to determine the phylogenetic position of this species. it ... | 2003 | 21156600 |
| three diketopiperazine alkaloids with spirocyclic skeletons and one bisthiodiketopiperazine derivative from the mangrove-derived endophytic fungus penicillium brocae ma-231. | four new diketopiperazines including spirobrocazines a-c (1-3) and brocazine g (4) were characterized from the mangrove-derived penicillium brocae ma-231. compounds 1 and 2 had a 6/5/6/5/6 cyclic system with a rare spirocyclic center at c-2. their structures and absolute configurations were determined by spectroscopic analysis, tddft-ecd calculations, and x-ray diffraction. compound 4 exhibited potent cytotoxicity against both sensitive and cisplatin-resistant human ovarian cancer cells and stro ... | 2016 | 27723361 |
| penicibrocazines a-e, five new sulfide diketopiperazines from the marine-derived endophytic fungus penicillium brocae. | five new sulfide diketopiperazine derivatives, namely, penicibrocazines a-e (1-5), along with a known congener (6), were isolated and identified from the culture extract of penicillium brocae ma-231, an endophytic fungus obtained from the fresh tissue of the marine mangrove plant avicennia marina. the structures of these compounds were elucidated by detailed interpretation of nmr and mass spectroscopic data and the structures of compounds 1 and 3 were confirmed by single-crystal x-ray diffractio ... | 2015 | 25574740 |
| brocazines a-f, cytotoxic bisthiodiketopiperazine derivatives from penicillium brocae ma-231, an endophytic fungus derived from the marine mangrove plant avicennia marina. | six new disulfide-bridged diketopiperazine derivatives, brocazines a-f (1-6), along with one known analogue (7), were isolated and identified from the cytotoxic extract of penicillium brocae ma-231, a fungus obtained from the fresh tissue of the marine mangrove plant avicennia marina. the structures of these compounds were established on the basis of detailed interpretation of nmr and mass spectroscopic data. x-ray crystallographic analysis confirmed the structure of 1 and established the struct ... | 2014 | 25105722 |
| fungal biodegradation of phthalate plasticizer in situ. | this unique study describes how aspergillus japonicus, penicillium brocae and purpureocillium lilacinum, three novel isolates of our laboratory from heavily plastics-contaminated soil completely utilized the plasticizer di(2-ethylhexyl)phthalate (dehp) bound to pvc blood storage bags (bb) in simple basal salt medium (bsm) by static submerged growth (28 °c). initial quantification as well as percentage utilization of dehp blended to bb were estimated periodically by extracting it into n-hexane. a ... | 2013 | 22903609 |
| occurrence of penicillium brocae and penicillium citreonigrum, which produce a mutagenic metabolite and a mycotoxin citreoviridin, respectively, in selected commercially available rice grains in thailand. | commercially available rice grains in thailand were examined to isolate the monoverticillate penicillium species responsible for toxic yellowed rice. penicillium species were obtained from seven out of 10 rice samples tested. among them, one penicillium citreonigrum isolate and six penicillium brocae isolates were morphologically identified. the p. citreonigrum isolate produced the mycotoxin citreoviridin on a yeast extract sucrose broth medium. mycotoxin surveys showed that citreoviridin was no ... | 2017 | 28617318 |