| [migraine and fumaria officinalis]. | | 1967 | 5598644 |
| protopine alkaloids in horse urine. | protopine was extracted from fumaria officinalis and purified by column chromatography. urine samples were collected from horses and a human volunteer that had been administered either f. officinalis or protopine free base. plant and urine samples were acetylated and analysed by gcms after solid-phase extraction (spe). the urinary metabolites of protopine were identified as 4,6,7,13-tetrahydro-9,10-dihydroxy-5-methyl-benzo[e]-l,3-benzodioxolo [4,5-1][2] benzazecin-12(5h)-one, 4,6,7,13-tetrahydro ... | 2004 | 15458726 |
| thin-layer chromatography of alkaloids on cyanopropyl bonded stationary phases. part i. | selected alkaloids are chromatographed on cyanopropyl-silica thin layers using various nonaqueous and aqueous eluents. because of the strong retention of these basic compounds, nonaqueous eluents containing medium polar diluents, strongly polar modifiers, and silanol blockers (ammonia or diethylamine) are required for separation. likewise, aqueous eluents containing modifiers (acetonitrile, methanol, and tetrahydrofuran), buffered aqueous solutions at ph 2-8, ion-pair reagents [octane sulfonic a ... | 2007 | 17725873 |
| in vitro trematocidal effects of crude alcoholic extracts of artemisia annua, a. absinthium, asimina triloba, and fumaria officinalis : trematocidal plant alcoholic extracts. | trematode infections negatively affect human and livestock health, and threaten global food safety. the only approved human anthelmintics for trematodiasis are triclabendazole and praziquantel with no alternative drugs in sight. we tested six crude plant extracts against adult schistosoma mansoni, fasciola hepatica, and echinostoma caproni in vitro. mortality was best achieved by ethanolic extracts of artemisia annua (sweet annie), asimina triloba (paw-paw), and artemisia absinthium (wormwood) w ... | 2011 | 21562762 |
| protopine and allocryptopine increase mrna levels of cytochromes p450 1a in human hepatocytes and hepg2 cells independently of ahr. | the isoquinoline alkaloids protopine and allocryptopine are present in phytopreparations from medicinal plants, such as fumaria officinalis. since nothing is known about effects of the alkaloids on the expression of xenobiotic-metabolizing enzymes, we examined whether protopine or allocryptopine affect the expression of cytochromes p450 (cyps) 1a1 and 1a2 in primary cultures of human hepatocytes and human hepatoma hepg2 cells. in hepg2 cells, protopine and allocryptopine significantly increased ... | 2011 | 21419197 |
| [the flavone heterosides of the fumitory. fumaria officinalis l., fumariaceae]. | | 1971 | 5149947 |
| [amphocholeretic effect of fumaria officinalis]. | | 1971 | 5134143 |
| [effect of nebulized fumaria officinalis on experimental gallbladder calculi in mice]. | | 1973 | 4794071 |
| alkaloids of fumaria officinalis. | | 1973 | 4773119 |
| [optimization of conditions for extraction of alkaloids from fumaria officinalis]. | | 2014 | 4817299 |
| [fumaria officinalis (fumitory)--clinical applications]. | fumaria officinalis-fumitory or earth smoke-is a medicinal plant which has long had a role to play in empirical medicine in numerous countries. a review of the literature, however, reveals very few studies that support its use for dermatological indications (milk crust, eczema, scabies, etc.) or as a diuretic or laxative. this contrasts with its use to treat functional diseases of the biliary system. although no placebo-controlled studies have been done, a number of empirical reports, clinical c ... | 1995 | 7672742 |
| 1h and 13c nmr signal assignment of benzylisoquinoline alkaloids from fumaria officinalis l. (papaveraceae). | the nmr signal assignments of a series of structurally divergent benzylisoquinolines isolated from fumaria officinalis l. (fumariaceae, papaverales), namely adlumine, corlumine, corydamine, cryptopine, fumarophycine, o-methylfumarophycine, hydrastine, parfumine, protopine and sinactine, are presented. | 2004 | 15366062 |
| herbal medicine with curcuma and fumitory in the treatment of irritable bowel syndrome: a randomized, placebo-controlled, double-blind clinical trial. | irritable bowel syndrome (ibs) is a common functional disorder for which there is no reliable medical treatment. the aim of this study was to determine the efficacy of two herbal remedies used in the treatment of ibs. | 2005 | 16173134 |
| quantification of fumaria officinalis isoquinoline alkaloids by nonaqueous capillary electrophoresis-electrospray ion trap mass spectrometry. | a capillary electrophoresis (ce) method using non-aqueous (na) separation solutions combined with an ion trap mass spectrometer (ms and ms/ms) as detection device is presented for the separation, identification and quantification of isoquinoline alkaloids from fumaria officinalis. the best results were obtained with a mixture of acetonitrile-methanol (9:1, v/v) containing 60mm ammonium acetate and 2.2m acetic acid as running electrolyte and an applied voltage of 30 kv. electrospray ms measuremen ... | 2006 | 16378615 |
| tlc of alkaloids on cyanopropyl bonded stationary phases. part ii. connection with rp18 and silica plates. | some standards of the alkaloids and synthetic or natural mixtures are separated by two-dimensional thin-layer chromatography (tlc) on different adsorbent layers. normal- and reversed-phase systems are used to obtain significant differences in the separation selectivity. optimization of the one-dimensional tlc separation of the alkaloids' standards is performed on cyanopropyl-silica, rp18w, and silica layers in various eluents containing (besides diluent and modifier) silanol blockers, such as di ... | 2008 | 18402718 |
| effect of chromatographic conditions on the separation and system efficiency for hplc of selected alkaloids on different stationary phases. | retention parameters of alkaloid standards were determined on different stationary phases, i.e., octadecyl silica, base-deactivated octadecyl silica, cyanopropyl silica, preconditioned cyanopropyl silica, and pentafluorophenyl, using different aqueous eluant systems: acetonitrile-water mixtures; buffered aqueous mobile phases at ph 3 or 7.8; and aqueous eluants containing ion-pairing reagents (octane-1-sulfonic acid sodium salt and pentane-1-sulfonic acid sodium salt) or silanol blockers (tetrab ... | 2011 | 21391483 |
| herbal medicines for the management of irritable bowel syndrome: a comprehensive review. | irritable bowel syndrome (ibs) is a functional gut disorder with high prevalence. because of various factors involved in its pathophysiology and disappointing results from conventional ibs medications, the treatment of ibs is challenging and use of complementary and alternative medicines especially herbal therapies is increasing. in this paper, electronic databases including pubmed, scopus, and cochrane library were searched to obtain any in vitro, in vivo or human studies evaluating single or c ... | 2012 | 22363129 |
| combined hplc-dad-ms, hplc-ms(n) and nmr spectroscopy for quality control of plant extracts: the case of a commercial blend sold as dietary supplement. | the efficiency of 1d and 2d nmr spectroscopy along with hplc-dad-ms analyses in characterising the content of a dietary supplement is demonstrated. experiments directly performed on a lyophilised sample of a commercial product gave details on the quality control of the product. the lack of the marker constituents of some of the declared plant species (crataegus oxyacantha, olea europea, capsella bursa-pastoris and fumaria officinalis) and the presence of banned adulterants, responsible for the s ... | 2014 | 24013031 |
| protopine production by fumaria cell suspension cultures: effect of light. | protopine biosynthesis in fumaria rostellata and fumaria officinalis cell suspensions was investigated. for the first time, we reported for calli and cell suspensions obtained from f. rostellata and f. officinalis. callus induction was initiated on a murashige and skoog medium, supplemented with sucrose and various concentrations of plant growth regulators: 2,4-dichlorophenoxyacetic acid (2,4-d) and 6-benzylaminopurine (bap). the best morphological characteristics, growth behavior, and protopine ... | 2015 | 25820387 |
| isoquinoline alkaloids from fumaria officinalis l. and their biological activities related to alzheimer's disease. | two new isoquinoline alkaloids, named fumaranine (2) and fumarostrejdine (10), along with 18 known alkaloids were isolated from aerial parts of fumaria officinalis. the structures of the isolated compounds were elucidated on the basis of spectroscopic analyses and by comparison with literature data. the absolute configuration of the new compound 2 was determined by comparing its circular dichroism spectra with those of known analogs. compounds isolated in sufficient amounts were evaluated for th ... | 2016 | 26765356 |
| total phenolic content, antioxidant and antimicrobial activities of some medicinal plants. | crude extracts from inula aucherana, fumaria officinalis, crocus sativus, vicum album, tribulus terestris, polygonatum multiflorum, alkanna tinctoria and taraxacum officinale were screened for their in vitro antioxidant and antimicrobial properties. total phenolic content of extracts from these plants were also determined. beta-carotene bleaching assay and folin-ciocalteu reagent were used to determine total antioxidant activity and total phenols of plant extracts. antimicrobial activity was det ... | 2009 | 19168430 |