| verruculotoxin, a new mycotoxin from penicillium verruculosum. | | 1975 | 1145632 |
| letter: structure and synthesis of verruculotoxin, a new mycotoxin from penicillium verruculosum peyronel. | | 1976 | 1244370 |
| ng-011 and ng-012, novel potentiators of nerve growth factor. i. taxonomy, isolation, and physico-chemical and biological properties. | ng-011 and ng-012, novel potentiators of nerve growth factor (ngf), were isolated from the culture broth of penicillium verruculosum f-4542, together with 3,4-dihydro-6,8-dihydroxy-3-methylisocoumarin. they potentiated the neurite outgrowth induced by ngf in rat pheochromocytoma cell line (pc12). | 1992 | 1473982 |
| ng-011 and ng-012, novel potentiators of nerve growth factor. ii. the structure determination of ng-011 and ng-012. | ng-011 and ng-012, novel potentiators of nerve growth factor (ngf) were isolated from the culture broth of penicillium verruculosum f-4542. the structures of ng-011 and ng-012 were elucidated by their spectral analysis and degradation experiments as shown in fig. 1. | 1992 | 1473983 |
| tremorgenic toxin from penicillium veruculosum. | a new mycotoxin that produces severe tremors and acute toxicity when administered orally or intraperitoneally (ip) to mice and 1-day-old cockerels was obtained from a strain of penicillium verruculosum peyronel isolated from peanuts. the ip 50% lethal dose (ld(50)) of this tremorgen was 2.4 mg/kg in mice and 15.2 mg/kg in chickens. orally administered ld(50) values for the toxin were 126.7 mg/kg in mice and 365.5 mg/kg in chickens. the trivial name "verruculogen" is proposed for this tremorgenic ... | 1972 | 4341967 |
| letter: structure of verruculogen, a tremor producing peroxide from penicillium verruculosum. | | 1974 | 4414411 |
| isolation of myosin light chain kinase inhibitors from microorganisms: dehydroaltenusin, altenusin, atrovenetinone, and cyclooctasulfur. | dehydroaltenusin, cyclooctasulfur, atrovenetinone, and altenusin were isolated from the culture broths of penicillium verruculosum iam-13756, streptomyces verticillus subsp. tskushiensis atcc-21633, penicillium sp. spc-16375, and penicillium sp. spc-16524, respectively, as new myosin light chain kinase (mlck) inhibitors. these compounds inhibited the calmodulin-dependent activity of mlck with ic50 values of 0.69, 0.86, 3.7, and 350 microm, respectively. among them, dehydroaltenusin was the best ... | 1995 | 7670197 |
| antifungal macrocyclic polylactones from penicillium verruculosum. | three macrocyclic polylactones have been isolated from penicillium verruculosum. two were found to be novel and the third to be identical with ng-012(1). their structures were elucidated by spectroscopic and chemical methods. a full assignment of 1h- and 13c-resonances in acetone-d6 are given for all three compounds. the compounds show antifungal activity. | 1993 | 8360106 |
| species-specific production of microbial volatile organic compounds (mvoc) by airborne fungi from a compost facility. | thirteen airborne fungal species frequently isolated in composting plants were screened for microbial volatile organic compounds (mvoc), i.e., aspergillus candidus, a. fumigatus, a. versicolor, emericella nidulans, paecilomyces variotii, penicillium brevicompactum, penicillium clavigerum, penicillium crustosum, penicillium cyclopium, penicillium expansum, penicillium glabrum, penicillium verruculosum, and tritirachium oryzae. air samples from pure cultures were sorbed on tenax gr and analyzed by ... | 1999 | 10448558 |
| study of protein adsorption on indigo particles confirms the existence of enzyme--indigo interaction sites in cellulase molecules. | adsorption of several crude and purified cellulases (from trichoderma reesei, penicillium verruculosum and chrysosporium lucknowense) on indigo particles and avicel cellulose was studied. much higher amounts of protein were bound to indigo than to cellulose under similar conditions. for different purified enzymes, the quantity of bound protein per mg of adsorbent (indigo or cellulose) varied in the range of 57-111 and 0-62 microg x mg(-1), respectively. however, in general, the enzyme adsorption ... | 2001 | 11267701 |
| [isolation and properties of cellobiase from penicillium verruculosum]. | cellobiase (beta-d-glucosidase) with a molecular weight of 100 kda and pi 5.2 was isolated from the cellulolytic system of penicillium verruculosum. kinetic parameters of enzymatic hydrolysis of cellobiose, gentiobiose, sophorose, and synthetic substrates, i.e. methylumbelliferyl and p-nitrophenyl sugar derivatives were determined. glucose and d-glucose-delta-lactone competitively inhibited cellobiase (ki = 0.19 mm and 17 microm, respectively). glucosyl transfer reactions were studied with cello ... | 2001 | 11771322 |
| [studies of hydrolytic activity of enzyme preparations of penicillium and trychoderma fungi]. | enzyme preparations were isolated from the culture liquid of five mutant strains of the cellulase producer penicillium verruculosum. the hydrolytic activities of these preparations against unbleached eucalypt cellulose was compared to that of commercial preparations of trichoderma reesei (t. longibrachiatum). in the majority of cases, p. verruculosum enzymes provided higher yields of reducing sugars (rss) and glucose. a correlation was found between the yield of rss and the avicelase activity of ... | 2005 | 15859466 |
| [the selection and properties of penicillium verruculosum mutants with enhanced production of cellulases and xylanases]. | the paper describes three penicillium verruculosum 28k mutants with about threefold enhanced production of five industrially important carbohydrases. the two-stage fermentation process that we developed provided a further two- to threefold increase in the production of carbohydrases. physiological and biochemical studies showed that the synthesis of all five carbohydrases is inducible. carboxymethylcellulase, xylanase, and beta-glucanase are synthesized under a common regulatory control, as is e ... | 2005 | 15938392 |
| design of highly efficient cellulase mixtures for enzymatic hydrolysis of cellulose. | an extremely highly active cellobiohydrolase (cbh iib or cel6b) was isolated from chrysosporium lucknowense uv18-25 culture filtrate. the cbh iib demonstrated the highest ability for a deep degradation of crystalline cellulose amongst a few cellobiohydrolases tested, including c. lucknowense cbh ia, ib, iia, and trichoderma reesei cbh i and ii. using purified c. lucknowense enzymes (cbh ia, ib, and iib; endoglucanases ii and v; beta-glucosidase, xylanase ii), artificial multienzyme mixtures were ... | 2007 | 17221887 |
| isolation and identification of vermistatin, ergosterol, stearic acid and mannitol, metabolic products of penicillium verruculosum. | | 1997 | 17252345 |
| isolation and properties of fungal beta-glucosidases. | using chromatography on different matrixes, three beta-glucosidases (120, 116, and 70 kda) were isolated from enzymatic complexes of the mycelial fungi aspergillus japonicus, penicillium verruculosum, and trichoderma reesei, respectively. the enzymes were identified by maldi-tof mass-spectrometry. substrate specificity, kinetic parameters for hydrolysis of specific substrates, ability to catalyze the transglucosidation reaction, dependence of the enzymatic activity on ph and temperature, stabili ... | 2009 | 19538132 |
| isolation and properties of xyloglucanases of penicillium sp. | using chromatographic technique, xyloglucanase (xg) a (25 kda, pi 3.5, 12th glycosyl hydrolase family) was isolated from the enzyme complex secreted by the mycelial fungus penicillium canescens, and xyloglucanases xg 25 (25 kda, pi 4.1, 12th glycosyl hydrolase family) and xg 70 (70 kda, pi 3.5, 74th glycosyl hydrolase family) were isolated from the enzyme complex of penicillium verruculosum. properties of the isolated enzymes (substrate specificity, optimal ranges of ph and temperature for enzym ... | 2010 | 20331423 |
| cellulases of penicillium verruculosum. | nine major cellulolytic enzymes were isolated from a culture broth of a mutant strain of the fungus penicillium verruculosum: five endo-1, 4-beta-glucanases (egs) having molecular masses 25, 33, 39, 52, and 70 kda, and four cellobiohydrolases (cbhs: 50, 55, 60, and 66 kda). based on amino acid similarities of short sequenced fragments and peptide mass fingerprinting, the isolated enzymes were preliminary classified into different families of glycoside hydrolases: cel5a (eg iia, 39 kda), cel5b (e ... | 2010 | 20540109 |
| decalpenic acid, a novel small molecule from penicillium verruculosum cr37010, induces early osteoblastic markers in pluripotent mesenchymal cells. | osteoblasts are the cells responsible for bone formation during embryonic development and adult life. small compounds that could induce osteoblast differentiation might be promising sources of therapies for bone diseases such as osteoporosis. during screening for inducers of osteoblast differentiation of mouse pluripotent mesenchymal c3h10t1/2 cells, we isolated a small compound from the fermentation broth of penicillium verruculosum cr37010. this compound, named decalpenic acid, bears a decalin ... | 2010 | 20940725 |
| (e)-3-[2,5-dioxo-3-(propan-2-yl-idene)pyrrolidin-1-yl]acrylic acid. | the title compound, c(10)h(11)no(4), was extracted from a culture broth of penicillium verruculosum yl-52. the mol-ecular structure is essentially planar, with an r.m.s. deviation of 0.01342 (2) å for the non-h atoms. in the crystal structure, adjacent mol-ecules are connected into a centrosymmetric dimer through a pair of o-h⋯o hydrogen bonds. the dimers are further extended into a chain by weak c-h⋯o hydrogen bonds. | 2010 | 21580390 |
| Production of cellulase enzymes during the solid-state fermentation of empty palm fruit bunch fiber. | Penicillium verruculosum COKE4E is a fungal strain isolated from bituminous coal. The microorganism cultivated in a minimal medium supplemented with Avicel, carboxymethylcellulose, and oat spelt xylan produced cellulase enzymes as exhibiting carboxymethylcellulase (CMCase), Avicelase, xylanase, and cellobiosidase activities. In this study, the productivity of the extracellular enzymes in the strain was evaluated by using empty palm fruit bunch fiber (EPFBF), a lignocellulosic biomass, as a subst ... | 2011 | 22052232 |