| [regeneration of mesencephalon in the larvae of discoglossus sardus (tschudi) and bufo bufo(l.)]. | | 1970 | 4999478 |
| ontogeny of the bizarre: an osteological description of pipa pipa (anura: pipidae), with an account of skeletal development in the species. | the adult osteology of the direct-developing pipid frog, pipa pipa, is described based on cleared-and-stained and dry skeletal specimens. observations on skeletal development are based on cleared-and-stained embryos and young removed from the backs of preserved females. osteologically, p.pipa is distinguished from its congeners and other pipid anurans by its large size and peculiar skull, which is extremely depressed and hyperossified. skulls of the smallest individuals are not significantly dif ... | 2000 | 10629097 |
| fatal chytridiomycosis in the tyrrhenian painted frog. | batrachochytrium dendrobatidis (bd), the causative agent of the amphibian disease chytridiomycosis, is an important factor in the global decline of amphibians. within europe, animals that exhibit clinical signs of the disease have only been reported in spain despite the pathogen's wide, but patchy, distribution on the continent. recently, another occurrence of chytridiomycosis was reported in euproctus platycephalus, the sardinian brook newt, on the mediterranean island of sardinia, but without ... | 2009 | 19418096 |
| a family of antimicrobial and immunomodulatory peptides related to the frenatins from skin secretions of the orinoco lime frog sphaenorhynchus lacteus (hylidae). | peptidomic analysis of norepinephrine-stimulated skin secretions of the orinoco lime tree frog sphaenorhynchus lacteus (hylidae, hylinae) revealed the presence of three structurally related host-defense peptides with limited sequence similarity to frenatin 2 from litoria infrafrenata (hylidae, pelodryadinae) and frenatin 2d from discoglossus sardus (alytidae). frenatin 2.1s (glvgtllghigkailg.nh2) and frenatin 2.2s (glvgtllghigkails.nh2) are c-terminally α-amidated but frenatin 2.3s (glvgtllghigk ... | 2014 | 24704757 |
| an immunomodulatory peptide related to frenatin 2 from skin secretions of the tyrrhenian painted frog discoglossus sardus (alytidae). | norepinephrine-stimulated skin secretions of the tyrrhenian painted frog discoglossus sardus tschudi, 1837 (alytidae) did not contain any peptide with antimicrobial or hemolytic activity. however, peptidomic analysis of the secretions revealed the presence of an abundant peptide with structural similarity to frenatin 2, previously isolated from the australian frog litoria infrafrenata (hylidae). the primary structure of the peptide, termed frenatin 2d, was established as dllgtlgnlplpfi.nh2 by au ... | 2013 | 23262358 |
| osteology and skeletal development of discoglossus sardus (anura:discoglossidae). | although frogs in the archaeobatrachian family discoglossidae are reasonably well known, descriptions of their larval skeletons and osteogenesis are almost nonexistent. skeletogenesis, chondrocranial development, and the adult skeleton of discoglossus sardus are described on the basis of cleared and stained, dry, and radiographed specimens. in d. sardus, the first elements to ossify are the parasphenoid, frontoparietals, exoccipitals, neural arches, ischium, long bones, and dermal elements of th ... | 1997 | 9259125 |
| insulinotropic activity of the host-defense peptide frenatin 2d: conformational, structure-function and mechanistic studies. | of four naturally occurring frenatin peptides tested, frenatin 2d (dllgtlgnlplpfi.nh2) from discoglossus sardus was the most potent and effective in producing concentration-dependent stimulation of insulin release from brin-bd11 rat clonal β-cells without displaying cytotoxicity. the peptide also stimulated insulin release from 1.1b4 human-derived clonal β-cells and isolated mouse islets and improved glucose tolerance concomitant with increased circulating insulin concentrations in mice followin ... | 2019 | 30244134 |