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the end of the fat dodo? a new mass estimate for raphus cucullatus.a new mass estimate for the dodo (raphus cucullatus), based on the lengths of the femur, tibiotarsus and tarsometatarsus, is attempted. the obtained mean mass is 10.2 kg, which is less than previous estimates based on other methods, which ranged from 10.6 to 21.1 kg, and much lower than the 50 lbs reported by a seventeenth-century eyewitness. the new estimated mass, which is similar to that of a large wild turkey, seems more realistic than previous ones and supports the hypothesis that contempor ...201121240603
chemotherapy dose and schedule in adjuvant treatment of breast cancer: phoenix, turkey, or dodo? 200312957087
strengths and weaknesses of current polio vaccines--a view from industry.polio eradication is within our grasp and, unless something terribly wrong and unexpected happens, the three types of wild polioviruses will cease to circulate in human populations within the next few years. this achievement will be a result of the rational use of opv. a momentous global decision--discontinuation of vaccination--will then have to be taken. the most important uncertainty that will weigh upon that decision is whether wild polioviruses can re-emerge after "eradication" defined as " ...200111763338
the dodo gene family encodes a novel protein involved in signal transduction and protein folding.recent studies in yeast, drosophila and humans have revealed the existence of a highly conserved gene encoding a novel protein, dodo, comprised of four modules: a ww domain, involved in protein-protein interactions, a peptidyl-prolyl cis-trans isomerase (ppiase) domain belonging to a recently described third family of ppiases involved in protein folding and unfolding, a nuclear localization motif and finally, a long, surface-exposed alpha-helix that is likely to be involved in binding to a cell ...19979426238
effect of mango weevil (coleoptera: curculionidae) damage on mango seed viability in tanzania.studies were conducted at the horticulture unit of sokoine university of agriculture, morogoro, tanzania, to assess the incidence and effect of mango weevil, cryptorhynchus mangiferae (f.) (coleoptera: curculionidae), infestation on mango, mangifera indica l., seed viability. three polyembryo mango cultivars ('sindano nyeusi', 'sindano nyeupe', and 'dodo') as well as three monoembryo mango cultivars ('ex-horticulture', 'tango', and 'bongwa') were collected and examined for the presence of c. man ...200818330124
assembling the dodo in early modern natural history.this paper explores the assimilation of the flightless dodo into early modern natural history. the dodo was first described by dutch sailors landing on mauritius in 1598, and became extinct in the 1680s or 1690s. despite this brief period of encounter, the bird was a popular subject in natural-history works and a range of other genres. the dodo will be used here as a counterexample to the historical narratives of taxonomic crisis and abrupt shifts in natural history caused by exotic creatures co ...201526256311
medical school lectures--as dead as the dodo. 201323281879
convex-hull mass estimates of the dodo (raphus cucullatus): application of a ct-based mass estimation technique.the external appearance of the dodo (raphus cucullatus, linnaeus, 1758) has been a source of considerable intrigue, as contemporaneous accounts or depictions are rare. the body mass of the dodo has been particularly contentious, with the flightless pigeon alternatively reconstructed as slim or fat depending upon the skeletal metric used as the basis for mass prediction. resolving this dichotomy and obtaining a reliable estimate for mass is essential before future analyses regarding dodo life his ...201626788418
effectiveness and efficiency in the treatment of gambling disorder: reflections on the dodo bird conjecture.in the field of research into the treatment of problem gambling, researchers have been attempting to identify the treatment pathways that are effective in remediating gambling disorder among people seeking help. in spite of these efforts, research results remain equivocal in relation to which components of the various treatment options are effective, echoing the familiar claim that all psychotherapy treatments are effective, the dodo bird conjecture.this recent tendency towards the revival of th ...201626791758
chernobyl's shield, dodo skeleton and hiv vaccines. 201627905458
from efficacy to pragmatic trials: does the dodo bird verdict apply? 201727914904
bone histology sheds new light on the ecology of the dodo (raphus cucullatus, aves, columbiformes).the dodo, raphus cucullatus, a flightless pigeon endemic to mauritius, became extinct during the 17(th) century due to anthropogenic activities. although it was contemporaneous with humans for almost a century, little was recorded about its ecology. here we present new aspects of the life history of the dodo based on our analysis of its bone histology. we propose that the dodo bred around august and that the rapid growth of the chicks enabled them to reach a robust size before the austral summer ...201728839147
effects of health-care services and commodities cost on the patients at the primary health facilities in zaria metropolis, north western nigeria.the payment for health-care services is a major problem for many poor patients in developing nations. the aim of the study was to examine the cost of services and commodities and how these affect the patients who utilizes the primary health-care centers in zaria, north western nigeria.201728891549
from dodo bird to mindfulness: the effect of theoretical orientation on work and self.i discuss my transformation from a confused graduate student with a common factors theoretical orientation to a licensed psychologist focused on humanistic, cognitive, and mindfulness approaches. my theoretical journey was shaped by my work with clients and my own personal development and primarily motivated by a sense of uncertainty that accompanied the lack of a specific theoretical identity. this discussion of trying to find the "right" theoretical approach is set against the well-supported e ...201424953554
high connectivity of animal populations in deep-sea hydrothermal vent fields in the central indian ridge relevant to its geological setting.dispersal ability plays a key role in the maintenance of species in spatially and temporally discrete niches of deep-sea hydrothermal vent environments. on the basis of population genetic analyses in the eastern pacific vent fields, dispersal of animals in the mid-oceanic ridge systems generally appears to be constrained by geographical barriers such as trenches, transform faults, and microplates. four hydrothermal vent fields (the kairei and edmond fields near the rodriguez triple junction, and ...201324358117
drosophila peptidyl-prolyl isomerase pin1 modulates circadian rhythms via regulating levels of period.in animal circadian clock machinery, the phosphorylation program of period (per) leads to the spatio-temporal regulation of diverse per functions, which are crucial for the maintenance of ~24-hr circadian rhythmicity. the peptidyl-prolyl isomerase pin1 modulates the diverse functions of its substrates by inducing conformational changes upon recognizing specific phosphorylated residues. here, we show that overexpression of drosophila pin1, dodo (dod), lengthens the locomotor behavioral period. us ...201525998391
refuge-effect hypothesis and the demise of the dodo.the dodo was last sighted on the inshore island of ile d'ambre in 1662, nearly 25 years after the previous sighting on the mainland of mauritius. it has been suggested that its survival on the inshore island is representative of the refuge effect. understanding what constitutes significant persistence is fundamental to conservation. i tested the refuge-effect hypothesis for the persistence of the dodo (raphus cucullatus) on an inshore island beyond that of the mainland population. for a location ...201323992554
[on the present situation in psychotherapy and its implications - a critical analysis of the facts].the currently dominating research paradigm in evidence-based medicine is expounded and discussed regarding the problems deduced from so-called empirically supported treatments (est) in psychology and psychotherapy. prevalent political and economic as well as ideological backgrounds influence the present dominance of the medical model in psychotherapy by implementing the randomized-controlled research design as the standard in the field. it has been demonstrated that randomized controlled trials ...201526175169
the drosophila melanogaster dodo (dod) gene, conserved in humans, is functionally interchangeable with the ess1 cell division gene of saccharomyces cerevisiae.we have sequenced the region of dna adjacent to and including the flightless (fli) gene of drosophila melanogaster and molecularly characterized four transcription units within it, which we have named tweety (twe), flightless (fli), dodo (dod), and penguin (pen). we have performed deletion and transgenic analysis to determine the consequences of the quadruple gene removal. only the flightless gene is vital to the organism; the simultaneous absence of the other three allows the overriding majorit ...19968552658
a revision of pheidole westwood (hymenoptera: formicidae) in the islands of the southwest indian ocean and designation of a neotype for the invasive pheidole megacephala.the myrmicine genus pheidole westwood is revised for the smaller islands of the southwest indian ocean: comoros, juan de nova island, mauritius, mayotte, reunion, and the seychelles. descriptions and keys are provided for the thirteen species on these islands of which seven are newly described: p. decepticon sp. n., p. dodo sp. n., p. komori sp. n, p. loki sp. n., p. megatron sp. n., p. ragnax sp. n., p. vulcan sp. n.; and six were previously described: p. braueri forel, p. fervens smith, f., p. ...201325250457
the evolutionary significance of mass extinctions.local extinctions of populations, species or groups of species in a particular area are commonly observed by biologists. there are also historical records of the total extinction of single species such as the dodo, the great auk and the tasmanian wolf. mass extinctions are on a much larger scale, and their study is based on the fossil record. the aims of this review are to explore the nature of mass extinctions and their evolutionary significance. the key questions are: what is mass extinction, ...198621227796
genetic engineering for removing food allergens from plants.genetic engineering has great potential for improving the safety of plant-based foods by eliminating allergenic components. a recent publication by dodo et al. demonstrates that rna interference can mediate the silencing of a major allergen protein from peanuts. three additional papers (two by le et al. and one by lorenz et al.) report the removal of allergenic proteins from tomato fruits. this research highlights the potential for using genetically engineered hypoallergenic plants in a new appr ...200818467156
academic surgery in new zealand: dodo or phoenix? 200818380726
routine psychological treatment and the dodo verdict: a rejoinder to clark et al. (2007). 200818261246
where is the forest? 201525678290
sadly, pyridoxalated hemoglobin polyoxyethylene is more a dodo than a phoenix. 201525514711
looking both ways.on the occasion of the 25th anniversary of the journal, psychotherapy research, three former editors first look back at: (i) the controversial persistence of the dodo verdict (i.e., the observation that all bona fide therapies seem equally effective); (ii) the connection between process and outcome; (iii) the move toward methodological pluralism; and (iv) the politicization of the field around evidence-based practice and treatment guidelines. we then look forward to the next 25 years, suggesting ...201525427829
perhaps it is the dodo bird verdict that should be extinct. 201020078458
palaeobiology: dutch diaries and the demise of the dodo. 200415190921
flightless birds: when did the dodo become extinct?the extinction of the dodo (raphus cucullatus l.; fig. 1) is commonly dated to the last confirmed sighting in 1662, reported by volkert evertsz on an islet off mauritius. by this time, the dodo had become extremely rare - the previous sighting having been 24 years earlier - but the species probably persisted unseen beyond this date. here we use a statistical method to establish the actual extinction time of the dodo as 1690, almost 30 years after its most recent sighting.200314628039
flight of the dodo. 200211872833
[farewell to the dodo-bird: specific versus general psychotherapy from the perspective of psychotherapy research].based upon different specificity problems in psychotherapy, it is shown that psychotherapy research consists of two different worlds, the one focussing on disorder specific factors, the other traditionally investigating unspecific or common therapeutic factors. relating to the dodobird verdict that has been used to describe the so-called equivalence paradox in psychotherapy, several views of common therapeutic factors are summarized. recent research shows that psychotherapy research also indicat ...200111689966
is the dodo bird endangered in the 21st century? a meta-analysis of treatment comparison studies.the dodo bird hypothesis asserts that when bona fide treatments are compared they yield similar outcomes and this hypothesis is consistent with a common factors or contextual model of psychotherapy. wampold et al. (1997), the most recent comprehensive meta-analysis to test the dodo bird hypothesis, yielded consistent evidence of treatment equivalence. however, some of wampold et al.'s analytic strategies, such as using multiple effect sizes from the same study and prioritizing long-term follow-u ...201425238455
empirically supported treatments in psychotherapy: towards an evidence-based or evidence-biased psychology in clinical settings?the field of research and practice in psychotherapy has been deeply influenced by two different approaches: the empirically supported treatments (ests) movement, linked with the evidence-based medicine (ebm) perspective and the "common factors" approach, typically connected with the "dodo bird verdict". about the first perspective, since 1998 a list of ests has been established in mental health field. criterions for "well-established" and "probably efficacious" treatments have arisen. the develo ...201021833197
optimal allocation of conservation resources to species that may be extinct.statements of extinction will always be uncertain because of imperfect detection of species in the wild. two errors can be made when declaring a species extinct. extinction can be declared prematurely, with a resulting loss of protection and management intervention. alternatively, limited conservation resources can be wasted attempting to protect a species that no longer exists. rather than setting an arbitrary level of certainty at which to declare extinction, we argue that the decision must tr ...201020214673
the mysterious spotted green pigeon and its relation to the dodo and its kindred.the closely related and extinct dodo (raphus cucullatus) and rodrigues solitaire (pezophaps solitaria), both in the subfamily raphinae, are members of a clade of morphologically very diverse pigeons. genetic analyses have revealed that the nicobar pigeon (caloenas nicobarica) is the closest living relative of these birds, thereby highlighting their ancestors' remarkable migration and morphological evolution. the spotted green pigeon (caloenas maculata) was described in 1783 and showed some simil ...201425027719
characterization and determination of lignin in different types of iraqi phoenix date palm pruning woods.this study aimed to find analytical data base for iraqi phoenix date palm pruning woods, which produced by pruning process at the season of date palm production. lignin has been extracted and purified for five types of iraqi date palm using klason lignin method. the weight of the extracted lignin ranged from 0.410 g to 0.720 g, and the lignin % ranged from 17.6 to 36. the other ingredients (waxes, oils, resin, and proteins of wood gums) % ranged from 20 to 29.5. ft-ir characterization showed tha ...201323811162
competing perspectives on erasing the stigma of illness: what says the dodo bird?the dodo bird is an alice in wonderland character who, at the end of a race, concludes "everybody has won and all must have prizes". the dodo bird effect has been used to describe a conundrum resulting from behavior change research that fails to distinguish superiority among discrete strategies for psychotherapeutic change. research on stigma change may find itself at this point. advocates have developed and implemented multiple approaches to changing stigma; some of these might be shown to have ...201423787069
discovery of new hydrothermal activity and chemosynthetic fauna on the central indian ridge at 18°-20° s.indian ocean hydrothermal vents are believed to represent a novel biogeographic province, and are host to many novel genera and families of animals, potentially indigenous to indian ocean hydrothermal systems. in particular, since its discovery in 2001, much attention has been paid to a so-called 'scaly-foot' gastropod because of its unique iron-sulfide-coated dermal sclerites and the chemosynthetic symbioses in its various tissues. despite increasing interest in the faunal assemblages at indian ...201222431990
dodo remains from an in situ context from mare aux songes, mauritius.since 2005, excavations at mare aux songes, mauritius, have revealed the presence of a very rich, ∼4,200-year-old fossil bone bed including dodo (raphus cucullatus) bones and bone fragments. the recently excavated dodo assemblage comprises at least 17 individuals and is characterised by the presence of small and fragile skeletal elements, a dominance of leg elements and an absence of juveniles. the hydrology of the area suggests that dodos, like many other species, were probably lured to mare au ...201222282037
mediators and moderators in meta-analysis: there's a reason we don't let dodo birds tell us which psychotherapies should have prizes.in primary studies, psychotherapy researchers frequently search for mediator and moderator variables that can help them understand the relationship between treatment and outcome. yet a review of past psychotherapy meta-analyses revealed that none examined the possible role of mediator variables; and although all of them searched for moderators of study outcome, that search was generally not as complete as it could have been. this article illustrates methods for studying such mediator and moderat ...19911837794
allocating resources to health care: is the qaly (quality adjusted life year) a technical solution to a political problem?the allocation of health care resources has always been and will remain a contentious issue. classically, the arguments have been posed in terms of the "need" for health care and/or the "right" to treatment. more recently, there have been attempts to shape the debate in consequentialist terms, by introducing a composite outcome measure. in the united kingdom, the qaly (quality adjusted life year) has been promoted enthusiastically. but, like many other such proposals, it is a dodo, and one that ...19912071312
quality assurance in europe: dead as the dodo? 198510276033
the dodo you save may be your own. 19846150629
the dodo and the tambalacoque tree. 197917780481
prolonged exposure, time-limited dynamic psychotherapy, and the dodo. 201121515201
the dodo was not so slim: leg dimensions and scaling to body mass. 201121380621
biogeography and diversification of hermit spiders on indian ocean islands (nephilidae: nephilengys).the origin of the terrestrial biota of madagascar and, especially, the smaller island chains of the western indian ocean is relatively poorly understood. madagascar represents a mixture of gondwanan vicariant lineages and more recent colonizers arriving via cenozoic dispersal, mostly from africa. dispersal must explain the biota of the smaller islands such as the comoros and the chain of mascarene islands, but relatively few studies have pinpointed the source of colonizers, which may include mai ...201121316478
sympathectomy revisited: dodo or phoenix?personal experience with temporary or permanent interruption of adrenergic impulses to brain, heart, kidney, pancreas, and the extemities is reviewed and certain concepts which were formulated long ago are re-emphasized. first, adrenergic blockade unmasks the cholinergic activity of the autonomic nervous system. this is apparent particularly when cardiac, renal, or pancreatic functions are studied under stress. second, in the immediate treatment of cerebral, cardiac, or digital ischemia, the pot ...1975242086
malaria in mauritius--as dead as the dodo. 19744609014
the technical exhibit: will it follow the dodo? 19705418771
island of the dodo. 196113723670
education for dermatology in the united states; some personal views on doctors, dermatologists, and dodos. 196013835677
diet kitchens are the dodos of hospital food service. 195212990125
that dodo again. 194818731361
the dodo flies again. 194718731291
is the dodo an extinct bird? 188617832802
is the dodo an extinct bird? 188617783344
is the dodo an extinct bird? 188617832700
is the dodo an extinct bird? 188617819515
is the dodo an extinct bird? 188617835083
obamacare-the way of the dodo. 201123137374
dodo: an efficient orthologous genes assignment tool based on domain architectures. domain based ortholog detection.orthologs are genes derived from the same ancestor gene loci after speciation events. orthologous proteins usually have similar sequences and perform comparable biological functions. therefore, ortholog identification is useful in annotations of newly sequenced genomes. with rapidly increasing number of sequenced genomes, constructing or updating ortholog relationship between all genomes requires lots of effort and computation time. in addition, elucidating ortholog relationships between distant ...201021106128
cognitive behaviour therapy (cbt) for the treatment of co-occurring depression and substance use: current evidence and directions for future research.issues and approach: the high rates of co-occurring depression and substance use, and the negative impact of this on illness course and outcomes have been well established. despite this, few clinical trials have examined the efficacy of cognitive behaviour therapy (cbt). this paper systematically reviews these clinical trials, with an aim of providing recommendations for how future research can develop a more robust evidence base for the treatment of these common comorbidities. leading electroni ...201020887574
core processes of psychopathology and recovery: "does the dodo bird effect have wings?".this editorial proposes that the task of identifying common processes across disorders and across psychotherapies will be the most fruitful way to develop efficient, easily trainable and coherent psychological interventions. the article adapts the concept of the 'dodo bird effect' to argue for a mechanistic, testable account of functioning, akin to other unified approaches in science. the articles in the special issue complement this perspective in several ways: (1) three articles identify commo ...201120624664
[the ferenczi-cult, the therapeutic technique and the dodo hypothesis]. 201020503847
the dodo bird verdict--controversial, inevitable and important: a commentary on 30 years of meta-analyses.in this article, the assertion that different psychological therapies are of broadly similar efficacy-often called the 'dodo bird verdict'-is contrasted with the alternative view that there are specific therapies that are more effective than others for particular diagnoses. we note that, despite thirty years of meta-analytic reviews tending to support the finding of therapy equivalence, this view is still controversial and has not been accepted by many within the psychological therapy community; ...201119728292
complete mitochondrial genomes of living and extinct pigeons revise the timing of the columbiform radiation.pigeons and doves (columbiformes) are one of the oldest and most diverse extant lineages of birds. however, the nature and timing of the group's evolutionary radiation remains poorly resolved, despite recent advances in dna sequencing and assembly and the growing database of pigeon mitochondrial genomes. one challenge has been to generate comparative data from the large number of extinct pigeon lineages, some of which are morphologically unique and therefore difficult to place in a phylogenetic ...201627782796
the human pin1 peptidyl-prolyl cis/trans isomerase gene maps to human chromosome 19p13 and the closely related pin1l gene to 1p31.the human pin1 gene encodes an essential nuclear peptidyl-prolyl cis/trans isomerase involved in the regulation of mitosis. pin1 is a member of a new class of peptidyl-prolyl cis/trans isomerases that includes the escherichia coli parvulin, yeast ess1, and drosophila melanogaster dodo gene products. analysis of human ests showed that there are two different but closely related human transcripts, one of which corresponds to pin1. gene localization, using both fish and tritium-labeled probes, show ...19979299231
the dodo or the phoenix? 200818552093
mitochondrial and nuclear dna sequences support a cretaceous origin of columbiformes and a dispersal-driven radiation in the paleocene .phylogenetic relationships among genera of pigeons and doves (aves, columbiformes) have not been fully resolved because of limited sampling of taxa and characters in previous studies. we therefore sequenced multiple nuclear and mitochondrial dna genes totaling over 9000 bp from 33 of 41 genera plus 8 outgroup taxa, and, together with sequences from 5 other pigeon genera retrieved from genbank, recovered a strong phylogenetic hypothesis for the columbiformes. three major clades were recovered wit ...200717661233
treating copd--the torch trial, p values, and the dodo. 200717314345
ornithology: digging for dodo. 200616971921
grizzlies, dodos and gore put science on film. 200616495960
medical thought of dosan manase's early years. (1) the meaning of the work "toryu".dosan manase was a famous japanese doctor in the muromachi era and was in the vanguard of the goseiha school of sino-japanese traditional medicine. in his "shinmyakukudenshu" we found an interesting account to explain the meaning of the word "toryu", which was often found in the medical books written in dosan's early years. this word signifies "our school" in a general sense, but in this book dosan used it with the additional meaning of his medical thought originating in zhu dan xi who was a fam ...199911624025
genetic characteristics of double hypoglossal canal as a nonmetric trait.the hypothesis that the hypoglossal canal bridging or double (hgcd), a nonmetric cranial trait, is a powerful discriminator between populations (dodo, 1980, 1987) is still controversial. to examine this issue, the incidences of hgcd were investigated in six inbred mice strains (cba, c57bl, balb/c, strong a, nzb, and dab) and one group of wild mice, six matings of cba and c57bl, and four experimental diet groups. the above hypothesis was supported by some results such as no effects of diet on the ...200111577438
paradigm clash: empirically supported treatments versus empirically supported psychotherapy practice.lampropoulos argues that the concerns of opponents of empirically supported treatments (ests) can be addressed within the est format. while this may be partially true, it does not address underlying paradigmatic concerns. i discuss paradigmatic differences and the dodo verdict, and present an alternative to the est paradigm. i argue that there are science-based forms of practice outside of the est paradigm.200021756119
sudden cardiac death & the reverse dodo verdict.adverse effects of treatment on cardiac qt intervals were first reported 50 years ago. a clear link to sudden death was established, but the problem remained relatively unknown. the issue of treatment related effects on the heart, and the contribution this might make to sudden cardiac deaths in general, came more clearly into focus 20 years ago, linked to regulatory actions. in an era of polypharmacy, and mixing of prescribed and non-prescribed pharmacologically active agents it is now becoming ...201424902504
the albatross and the dodo. 201424834613
observations on the nhs internal market: will the dodo get the last laugh?distinguishing between the theory and practice of the internal market has been obscured by the considerable controversy generated by the reforms themselves. in such an environment both the advocates and the opponents of a market based solution have tended to promote their respective claims by reference to underlying political philosophies and economic theories rather than practical experience. royce gives his observations of the actual operation of the internal market with particular reference t ...19957640593
rude awakenings.a new nurse recently complained in a national nursing publication that her manager, a 22-year veteran, refers to her staff as"dodos," "dipsticks" and "resident idiots." the vexed grad wanted to know whether she had to put up with this verbal abuse. it's amazing that she even had to ask. the los angeles times reports that rudeness is epidemic in america, as "embedded in the workplace culture as time cards, fluorescent lighting and computers." emts and paramedics are prime targets. you endure it f ...199510142525
buzzwords and baloney dodos and nurses. 19957613688
past-president's address. is the dodo bird really extinct? 1977609605
plant-animal mutualism: coevolution with dodo leads to near extinction of plant.an endemic sapotaceous tree calvaria major found on the island of mauritius is nearly extinct because its seeds apparently required passage through the digestive tract of the now-extinct dodo raphus cucullatus to overcome persistent seed coat dormancy caused by a specially thickened endocarp.197717730171
the mechanical ventilation sigh is a dodo. 197610314776
jugular foramen and mylohyoid bridging in an asian indian population.the incidence of jugular foramen and mylohyoid groove bridging was studied in a population of east asian indian skulls (125 males and 109 females). the criteria of dodo (j. anat. 144:153-165, 1986) was used in the identification of a jugular bridge. there was an overall incidence of 8.1% in jugular foramen bridging, with males showing a higher rate, though the difference did not reach statistical significance. the right side showed a statistically significant greater occurrence than the left, an ...20133605320
drosophila pin1 prolyl isomerase dodo is a map kinase signal responder during oogenesis.the mammalian cis-trans prolyl isomerase pin1 and its yeast orthologue ess1/ptf1 have been implicated in cell cycle control but a correlation between biochemical and physiological functions has not been established conclusively. pin1 targets the proline residue carboxy-terminal to the phosphorylated threonine or serine residue, which constitutes part of the phosphorylated mitogen-activated protein kinase (mapk) site pxpt/sp. here we show that the drosophila pin1 homologue, the dodo protein, is i ...200111389437
effect of ivermectin on infection with gastro-intestinal nematodes in sierra leone.levels of intestinal nematode infections were assessed six months after a two year trial of ivermectin for efficacy against onchocerciasis had ended. in the trial the inhabitants of six villages in sierra leone were offered treatment with ivermectin or placebo at six monthly intervals for four rounds in total. quantitative faecal egg counts were carried out on stool samples provided by 202 subjects, all of whom had received all four rounds of treatment, in two of the villages (dodo and mogibisi) ...19947829838
nursing and interdisciplinary research: phoenix or dodo?interdisciplinary research activities are increasing in health care in terms of amount and quality. it is recognised that the global problems facing humankind will not be solved by individual disciplines working in isolation. the purpose of this paper is to examine the issues facing interdisciplinary research and how it impacts on nursing in particular. some solutions to engendering cross disciplinary research are offered and a definition of interdisciplinary research is shared.202033061412
author correction: electrically pumped photonic integrated soliton microcomb.the original version of this article contained an error in the first sentence of the acknowledgements, which incorrectly read 'this publication was supported by contract hr0011-15-c-0055 (dodos) from the defense advanced research projects agency (darpa), defense sciences office (dso).' the correct version states 'microsystems technology office (mto)' in place of 'defense sciences office (dso)'. this has been corrected in both the pdf and html versions of the article.201930944332
day-on, day-off emtricitabine, tenofovir disoproxil fumarate and efavirenz single tablet regimen (dodo) as maintenance therapy in hiv-infected patients.reduced dose schedules may be feasible options to simplify antiretroviral therapy (art) in selected hiv-1-infected individuals. efficacy and safety of a day-on, day-off (dodo) schedule of tenofovir disoproxil fumarate, emtricitabine and efavirenz (ftc/tdf/efv) single tablet regimen (str) was assessed. twenty-seven patients were prescribed the dodo schedule and were monitored for 48 weeks. switching criteria were: no previous art failure, no aids-defining illnesses, t cd4 cell nadir >200/mmc, and ...201829932084
of dodo birds and common factors: a scoping review of direct comparison trials in adventure therapy.adventure therapy (at) is a term that includes therapies such as wilderness therapy and adventure-based counseling. with growing empirical support for at, the diversity of studies make it difficult to attribute outcomes to specific treatment factors.201829705449
correction: neither slim nor fat: estimating the mass of the dodo (raphus cucullatus, aves, columbiformes) based on the largest sample of dodo bones to date.[this corrects the article doi: 10.7717/peerj.4110.].201729327740
neither slim nor fat: estimating the mass of the dodo (raphus cucullatus, aves, columbiformes) based on the largest sample of dodo bones to date.the dodo (raphus cucullatus) might be the most enigmatic bird of all times. it is, therefore, highly remarkable that no consensus has yet been reached on its body mass; previous scientific estimates of its mass vary by more than 100%. until now, the vast amount of bones stored at the natural history museum in mauritius has not yet been studied morphometrically nor in relation to body mass. here, a new estimate of the dodo's mass is presented based on the largest sample of dodo femora ever measur ...201729230358
minimising interventions in the treatment and prevention of depression. taking the consequences of the 'dodo bird verdict'.research has shown that the different psychotherapeutic treatments in depression are equally effective. this could be accounted for by the non-specific factors, which all therapies have in common. on the other hand, too little is known about the effectiveness of the therapies in different groups of patients. research has shown that the format of the psychotherapies can be changed in several aspects without a reduction in effectiveness.199829052475
the dodo and its kindred; or the history, affinities, and osteology of the dodo, solitaire, and other extinct birds of the islands mauritius rodriguez, and bourbon. 184830164767
health care delivery and change: thoughts on lema's "... of dinosaurs, dodos and anesthesia personnel".problems in health care delivery relative to access, costs, and quality have been debated for more than a quarter of a century. health care costs have significantly increased since the implementation of the medicare/medicaid legislation. cost containment has been high on the agendas of government officials, legislators, health policy decision makers, business leaders, and economists since the 1980s. there has been a shift toward market medicine and managed care as a means for cost containment. a ...199910723299
[psychotherapy research--how it should (not) be done. an expert reanalysis of comparative studies by grawe et al. (1994)].22 psychotherapy outcome studies used in the bernese meta-analysis by grawe, donati and bernauer (1994) for a treatment comparison between behavioural and psychoanalytic-psychodynamic treatment concepts were reanalysed by 12 expert psychotherapy researchers independent of each other. three clinical criteria served as basic criteria for the assessment of the methodological quality of the 22 comparative studies: treatment dosage, therapists' competence or expertise, and an adequate realisation of ...19989857719
is the case study the evidence-base's equivalent to the dodo? 202032711893
the dodo bird is not extinct: ultrasound imaging for supraspinatus tendinosis. 201929979204
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