| isolation of a monoclonal antibody that blocks attachment of the major group of human rhinoviruses. | reciprocal competition binding assays have previously demonstrated that 20 of 24 human rhinovirus serotypes tested compete for a single cellular receptor. these studies suggested that the vast majority of rhinovirus serotypes utilize a single cellular receptor. with hela cells as an immunogen, a mouse monoclonal antibody was isolated which had the precise specificity predicted by the competition binding study. the receptor antibody was shown to protect hela cells from infection by 78 of 88 human ... | 1986 | 3001366 |