| brominated polyacetylenic acids from the marine sponge xestospongia muta: inhibitors of hiv protease. | the etoac extract of the sponge xestospongia muta collected in colombus island, bahamas, yielded eleven straight-chain unsaturated, polyacetylenic, brominated acids, seven of which were identified on the basis of spectral data, including the unknown acids 2-7. these acetylenic acids are the first known examples that have been shown to inhibit hiv protease, a critical enzyme in the replication of human immunodeficiency virus. | 1992 | 1431940 |
| novel actinobacteria from marine sponges. | actinobacteria exclusively within the sub-class acidimicrobidae were shown by 16s rdna community analysis to be major components of the bacterial community associated with two sponge species in the genus xestospongia. four groups of actinobacteria were identified in xestospongia spp., with three of these four groups being found in both xestospongia muta from key largo, florida and xestospongia testudinaria from manado, indonesia. this suggests that these groups are true symbionts in these sponge ... | 2005 | 15726288 |
| bleaching and stress in coral reef ecosystems: hsp70 expression by the giant barrel sponge xestospongia muta. | sponges are a prominent component of coral reef ecosystems. like reef-building corals, some sponges have been reported to bleach and die. the giant barrel sponge xestospongia muta is one of the largest and most important components of caribbean coral reef communities. tissues of x. muta contain cyanobacterial symbionts of the synechococcus group. two types of bleaching have been described: cyclic bleaching, from which sponges recover, and fatal bleaching, which usually results in sponge death. w ... | 2008 | 18331247 |
| generation of an affinity matrix useful in the purification of natural inhibitors of plasmepsin ii, an antimalarial-drug target. | an affinity matrix containing the antimalarial drug target plm ii (plasmepsin ii) as ligand was generated. this enzyme belongs to the family of plasmodium (malarial parasite) aspartic proteinases, known as plms (plasmepsins). the procedure established to obtain the support has two steps: the immobilization of the recombinant proenzyme of plm ii to nhs (n-hydroxysuccinimide)-activated sepharose and the activation of the immobilized enzyme by incubation at ph 4.4 and 37 degrees c. the coupling rea ... | 2009 | 18471091 |
| preliminary assessment of sponge biodiversity on saba bank, netherlands antilles. | saba bank atoll, netherlands antilles, is one of the three largest atolls on earth and provides habitat for an extensive coral reef community. to improve our knowledge of this vast marine resource, a survey of biodiversity at saba bank included a multi-disciplinary team that sampled fishes, mollusks, crustaceans, macroalgae, and sponges. | 2010 | 20502643 |
| the pathology of sponge orange band disease affecting the caribbean barrel sponge xestospongia muta. | the aim of this study was to examine sponge orange band (sob) disease affecting the prominent caribbean sponge xestospongia muta. scanning and transmission electron microscopy revealed that sob is accompanied by the massive destruction of the pinacoderm. chlorophyll a content and the main secondary metabolites, tetrahydrofurans, characteristic of x. muta, were significantly lower in bleached than in healthy tissues. denaturing gradient gel electrophoresis using cyanobacteria-specific 16s rrna ge ... | 2010 | 21118276 |
| transcriptional activity of the giant barrel sponge, xestospongia muta holobiont: molecular evidence for metabolic interchange. | compared to our understanding of the taxonomic composition of the symbiotic microbes in marine sponges, the functional diversity of these symbionts is largely unknown. furthermore, the application of genomic, transcriptomic, and proteomic techniques to functional questions on sponge host-symbiont interactions is in its infancy. in this study, we generated a transcriptome for the host and a metatranscriptome of its microbial symbionts for the giant barrel sponge, xestospongia muta, from the carib ... | 2015 | 25972851 |
| is there a trade-off between wound-healing and chemical defenses among caribbean reef sponges? | on caribbean coral reefs, some sponge species produce chemical defenses, while others do not and are non-fatally grazed by predatory fishes. it has been hypothesized that the latter may compensate for fish grazing by growing faster or rapidly healing wounds. rates of wound-healing were measured for chemically defended and undefended tubular and vase-shaped sponges on patch reefs in the florida keys and bahamas in 2002. healing rates were significantly faster during the first few days of the expe ... | 2005 | 21676780 |
| micro- and nano-structural characterization of six marine sponges of the class demospongiae. | the sponges produce their skeletal elements and silicateins are the key enzymes in this process. the mechanism underlying the formation of their silica skeleton and its structural properties are of exceptional interest for applications in technology. micro- and nano-scale structural analysis of the six marine sponges belonging to demospongiae [callyspongia (cladochalia) plicifera (lamarck, 1814), cervicornia cuspidifera (lamarck, 1815), cinachyrela sp., niphates erecta (duchassaing and michelott ... | 2016 | 27067435 |