| isolation of a newly recognized alphavirus from mosquitoes in vietnam and evidence for human infection and disease. | during studies of arboviral epidemiology in vietnam, five virus isolates were recovered from culex tritaeniorhynchus mosquitoes. three of the five isolates were identified as strains of japanese encephalitis virus, but the others, collected at me tri village, hanoi, were shown to represent an alphavirus, for which we propose the name me tri virus. this newly recognized virus is most closely related to semliki forest virus. the two isolates appear to be antigenic subtypes of a single virus, and e ... | 1995 | 7625527 |
| evolutionary relationships and systematics of the alphaviruses. | partial e1 envelope glycoprotein gene sequences and complete structural polyprotein sequences were used to compare divergence and construct phylogenetic trees for the genus alphavirus. tree topologies indicated that the mosquito-borne alphaviruses could have arisen in either the old or the new world, with at least two transoceanic introductions to account for their current distribution. the time frame for alphavirus diversification could not be estimated because maximum-likelihood analyses indic ... | 2001 | 11581380 |
| emerging zoonotic encephalitis viruses: lessons from southeast asia and oceania. | the last decade of the 20th century saw the introduction of an unprecedented number of encephalitic viruses emerge or spread in the southeast asian and western pacific regions (mackenzie et al, 2001; solomon, 2003a). most of these viruses are zoonotic, either being arthropod-borne viruses or bat-borne viruses. thus japanese encephalitis virus (jev), a mosquito-borne flavivirus, has spread through the indonesian archipelago to papua new guinea (png) and to the islands of the torres strait of nort ... | 2005 | 16287684 |
| me tri virus: a semliki forest virus strain from vietnam? | me tri virus (mtv) is a member of the semliki forest virus (sfv) complex in the genus alphavirus, first isolated from culex tritaeniorhynchus mosquitoes in vietnam in 1971 and described as a newly recognized alphavirus, based on antigenic characterization. however, based on a partial nucleotide sequence of the e1 envelope glycoprotein gene, it has recently been argued that mtv may represent a variant of sfv rather than a separate species. to enable definitive classification, we determined the co ... | 2008 | 18753222 |
| viral etiology of encephalitis in children in southern vietnam: results of a one-year prospective descriptive study. | acute encephalitis is an important and severe disease in children in vietnam. however, little is known about the etiology while such knowledge is essential for optimal prevention and treatment. to identify viral causes of encephalitis, in 2004 we conducted a one-year descriptive study at children's hospital number one, a referral hospital for children in southern vietnam including ho chi minh city. | 2010 | 21049060 |
| a brief review: the z-curve theory and its application in genome analysis. | in theoretical physics, there exist two basic mathematical approaches, algebraic and geometrical methods, which, in most cases, are complementary. in the area of genome sequence analysis, however, algebraic approaches have been widely used, while geometrical approaches have been less explored for a long time. the z-curve theory is a geometrical approach to genome analysis. the z-curve is a three-dimensional curve that represents a given dna sequence in the sense that each can be uniquely reconst ... | 2014 | 24822026 |
| recognition of protein-coding genes based on z-curve algorithms. | recognition of protein-coding genes, a classical bioinformatics issue, is an absolutely needed step for annotating newly sequenced genomes. the z-curve algorithm, as one of the most effective methods on this issue, has been successfully applied in annotating or re-annotating many genomes, including those of bacteria, archaea and viruses. two z-curve based ab initio gene-finding programs have been developed: zcurve (for bacteria and archaea) and zcurve_v (for viruses and phages). zcurve_c (for 57 ... | 2014 | 24822027 |