| [a study on the construction, expression and immunosterility of lagurus laguru zona pellucida 3 dna vaccine pvax1-sig-ltb-lzp3-c3d3]. | to enhance the immunocontraceptive effect of lagurus lagurus zona pellucida 3 dna vaccine, and to achieve the prospect of application through the pvax1-sig-ltb-lzp3-c3d3 different immunity pathway. | 2011 | 21906463 |
| [molecular adjuvant fai3 enhances the antifertility of lagurus lagurus zona pellucida 3 dna vaccine by intranasal route]. | to investigated whether fai3 as molecular adjuvant can enhance antifertility effect of contraceptive dna vaccine pcd-lzp3 through intranasal route. | 2010 | 21138678 |
| [morpho-functional characteristics of reproductive organs of rodents from the area affected by a plant, processing gas with the increased content of sulfur compounds]. | the biology of reproduction of 5 rodent species--small gopher (spermophilus pygmaeus pallas, 1778), reddish gopher (spermophilus major pallas, 1779), sasin lemmer (lagurus lagurus pallas,1773), forest mouse (apodemus sylvaticus linnaeus) and bank vole(clethrionomys glareolus schreber, 1780)--inhabiting the sanitary protective zone of the gas processing plant, was investigated with the use of histological, electron microscopical, immunocytochemical and morphometric methods. intensification of the ... | 2008 | 19102254 |
| [the immunocontraceptive effects of lagurus lagurus and mus musculus zona pellucida 3 dna vaccine]. | to investigate the immunocontraception effects of different kinds of mice and seek the relatively effective species-specific dna vaccines, we constructed four corresponding immunocontraceptive recombinant plasmids: pcdna3-mzp3 (pcd-m), pcdna3-izp3 (pcd-l), pcdna3-aat-comp-mzp3 (pcd-acm) and pcdna3-aat-comp-lzp3 (pcd-acl) using zona pellucida 3 gene of lagurus lagurus (lzp3) and mus musculus (mzp3) respectively to immunize nih mice. with the introduction of hydrnamic transfection instead of tradi ... | 2007 | 18254334 |
| [enhancing the induced immune responses of lagurus lagurus zona pellucida 3 dna vaccine by molecular adjuvant c3d]. | to investigate the enhancement of lagurus lagurus zona pellucida 3 gene (lzp3) immunization induced by molecular adjuvant c3d in comparison with plasmid pcdna3-lzp3 (pcd-l) in non-c3d fused form, the eukaryotic expression vector pcdna3-lzp3-c3d3 (pcd-lc) including lzp3 and three copies of c3d in fusion form was constructed. in vitro,rt-pcr and western blot showed that lzp3 mrna and protein were expressed in hela cells transfected with pcd-l and pcd-lc, respectively. in vivo,the result of elisa s ... | 2006 | 16955787 |
| lethal encephalitozoon cuniculi genotype iii infection in steppe lemmings (lagurus lagurus). | microsporidia are ubiquitous, spore-forming, intracellular parasites infecting invertebrates and vertebrates. some of them are important opportunistic pathogens in humans, including three species of genus encephalitozoon. intraspecies genetic variation with a different range of hosts is known in encephalitozoon cuniculi distinguishing four genotypes. recently, e. cuniculi is often observed in pet animals, mainly e. cuniculi genotype i in pet rabbits. this study described a fatal encephalitozoono ... | 2014 | 25073415 |
| [enhanced prokaryotic expression of a recombinant lagurus lagurus zona pellucida subunit 3 with codon optimization]. | to improve prokaryotic expression level of lagurus lagurus zona pellucida 3(lzp3) gene. | 2005 | 16256030 |
| sensitivity of european microtines to injected cdcl2. | basic histologic and metabolic indices of damage to the testes by cdcl2 were observed in six species of rodents: lagurus lagurus, pitymys subterraneus, microtus oeconomus, m. agrestis, clethrionomys glareolus (and mus musculus for comparison). all species showed discoloration of the subcapsular tissues and damage to the testicular parenchyma. testes of all species receiving cdcl2 utilized from 43% to 76% less oxygen than did those from untreated individuals. cadmium treatment preceded few signif ... | 1979 | 232358 |
| [somatic chromosomes of lagurus lagurus pall]. | | 2015 | 14183866 |
| karyotype and pattern of chromosome replication in lagurus lagurus pall (cricetidae, microtinae). | | 1968 | 5719203 |
| the implantation of astocysts in the russian steppe lemming (lagurus lagurus). | | 1970 | 5437464 |
| monogamy as one of the ways of realization of the adaptive potential in mammals as exemplified by the steppe lemming lagurus lagurus pallas. | | 2017 | 17425052 |
| transgenic rnai-mediated reduction of lzp3 in lagurus lagurus oocytes results in decreased fertilization ability in ivf. | structural differences in oligosaccharides on mammalian zona pellucida 3(zp3) from different species may determine whether or not spermatozoa being able to bind to zp. we reported here that by microinjecting the sirna interference recombinant construct pgenesil-zp31 encoding a lagurus zp3 (lzp3) hairpin dsrna of 21 bp into the inmatured oocytes of lagurus lagurus, distributed in northern region of xingjiang, to disturb its fertility. results of in vitro fertilization after in vitro maturation of ... | 2010 | 19301144 |
| parental care, aggressiveness, and testosterone secretion in male common voles (microtus arvalis) and steppe lemmings (lagurus lagurus). | | 2017 | 20506841 |
| odontogenic dysplasia in the molar teeth of steppe lemmings (lagurus lagurus). | in a colony of steppe lemmings (lagurus lagurus), of the rodent sub-family arvicolinae, 8.6% of animals exhibited dysplastic growth of the molar teeth. clinical findings included nodular swellings of the mandible, hypersalivation, malocclusion and emaciation. to investigate the underlying cause, two control and 10 affected animals, aged between 6 and 18 months, were examined using radiography and computed tomography and at post mortem examination. bilaterally symmetrical masses were identified i ... | 2011 | 20573534 |
| [care of young, aggressiveness, and secretion of testosterone in male rodents: a correlation analysis ]. | to test the current hypotheses on the relationship between the mating system, reproductive strategy, aggression, and secretion of testosterone, a comparative study of interactions in pair encounters, the level of parental care, and the gonadal testosterone level in males was performed in six rodent species (clethrionomys rutilus, meriones meridianus, microtus arvalis, lagurus lagurus, lasiopodomys mandarinus, and meriones unguiculatus) with different types of spatial-and-ethological population s ... | 2016 | 25510112 |
| molecular adjuvant interleukin-33 enhances the antifertility effect of lagurus lagurus zona pellucida 3 dna vaccine administered by the mucosal route. | it has been shown that cytokines can act as molecular adjuvant to enhance the immune response induced by dna vaccines, but it is unknown whether interleukin 33 (il-33) can enhance the immunocontraceptive effect induced by dna vaccines. in the present study, we explored the effects of murine il-33 on infertility induced by lagurus lagurus zona pellucida 3 (lzp3) contraceptive dna vaccine administered by the mucosal route. plasmid pcd-lzp3 and plasmid pcd-mil-33 were encapsulated with chitosan to ... | 2013 | 24345916 |
| dynamics of testosterone concentration in male steppe lemmings (lagurus lagurus) in the reproductive cycle reflects the species-specific mating system. | in the blood of male steppe lemmings, relatively low background levels of testosterone were detected, this is characteristic of a monogamous species. a significant increase in testosterone level, more expressed in sexually active males, was observed at the initial stage of formation of reproductive couples. apparently, in the future, the couple will exist in a stable relationship, and, hence, the maintenance of a high testosterone level becomes excessive. the decrease in, and the relative "norma ... | 2016 | 27411829 |
| [tumors induce in lagurus lagurus pall. by methylcholanthrene. a transplantable strain of sarcoma in lagurus]. | | 1960 | 13802361 |
| the steppe-lemming (lagurus lagurus pall.): a new animal suitable for cancer research. | | 1960 | 14433650 |
| [steppe lemming (lagurus lagurus pall.) as a new animal useful for experimental oncological research]. | | 1959 | 13659874 |
| [construction and expression of a recombinant adenovirus with lzp3]. | to explore a new immunocontraceptive vaccine and construct an attenuated recombinant adenoviral vaccine against lagurus lagurus zona pellucida 3(lzp3). | 2007 | 17618560 |
| [selecting the rnai efficiency target sites of lzp3 gene by mouse in vivo]. | as the combining target with sperms, zp3 undergoes an important role in the fertilization of oocytes and therefore it has been the focus in studying the mechanism of mammalian. according to the sequence of the zona pellucida 3 gene of lagurus lagurus (lzp3), three rna interference recombinant vectors were constructed with pgenesil-1 aiming at lzp3 mrna by synthesizing oligonucleotides. and then co-transfected into the hela cells by lipofectamine2000 and co-injected into the mice by hydrodynamics ... | 2006 | 17168323 |
| [experimental tumors in a steppelemmer (lagurus lagurus pall.)]. | | 1956 | 13352915 |
| meriones meridianus and lagurus lagurus as alternative definitive hosts of echinococcus multilocularis and e. granulosus. | the utilization of meriones meridianus and lagurus lagurus as alternative definitive hosts for echinococcus multilocularis and e. granulosus was investingated. tapeworm stage development of e. multilocularis was observed and their recovery rate was determined in the small intestine of m. meridianus and l. lagurus. these were compared with those in golden hamsters, which are known as alternative definitive hosts. the animals were treated with ptba (prednisolone tertiary butylacetate) and pa (pred ... | 2002 | 11871149 |
| [immunocontraceptive effect of dna vaccines of lagurus lagurus zona pellucida 3 fusioned with c-terminal of hsp70]. | to investigate the immunocontraceptive effect of lagurus lagurus zona pellucida 3 gene (lzp3) fused by mycobacterium tuberculosis hsp70 and c-terminal of hsp70. | 2008 | 18394342 |
| [materials for the study of the sensitivity of lagurus lagurus pall to the poliomyelitis virus. i. the possibility of utilization of lagurus lagurus pall for a study of poliomyelitis viruses types ii and iv]. | | 1960 | 13737591 |
| central asian rodents as model animals for leishmaniamajor and leishmania donovani research. | the clinical manifestation of leishmaniases depends on parasite species, host genetic background, and immune response. manifestations of human leishmaniases are highly variable, ranging from self-healing skin lesions to fatal visceral disease. the scope of standard model hosts is insufficient to mimic well the wide disease spectrum, which compels the introduction of new model animals for leishmaniasis research. in this article, we study the susceptibility of three asian rodent species (cricetulu ... | 2020 | 32962237 |
| [protective effects of leishmanial antigens against leishmania infantum infection in lagurus lagurus]. | to determine the protective effect of leishmanial surface antigens against experimental visceral leishmaniasis in lagurus lagurus caused by leishmania infantum. | 1999 | 12563775 |
| [comparative morpho-functional characteristics of the organs of the reproductive system of small mammals under conditions of anthropogenic transformation of southern ural steppe ecosystems]. | the morpho-functional characteristics of reproductive organs of small mammals--striped field mouse (apodemus agrarius pallas, 1771), house mouse (mus musculus linnaeus, 1758), wood mouse (sylvaemus uralensis pallas, 1811), common vole (microtus arvalis pallas, 1778), bank vole (clethrionomys glareolus schreber, 1780), steppe lemming (lagurus lagurus pallas, 1773), little suslik (spermophilus pygmaeus pallas, 1778), and red-heeked suslik (spermophilus major pallas, 1779)--belonging to the populat ... | 2013 | 24592716 |