| corynebacterium kroppenstedtii sp. nov., a novel corynebacterium that does not contain mycolic acids. | a strain of a hitherto undescribed coryneform bacterium from human clinical material was characterized by phenotypic and molecular taxonomic methods. comparative 16s rrna gene sequence analysis demonstrated the strain represents a novel and deep lineage within the genus corynebacterium sensu stricto. chemical analyses revealed the unidentified strain was unusual in that it lacked mycolic acids. based on the phylogenetic and phenotypic distinctiveness of the unknown isolate, it is proposed that t ... | 1998 | 9828448 |
| corynebacterium species isolated from patients with mastitis. | corynebacteria were isolated from breast tissue, pus, or deep wound swabs of 24 women; the most common species isolated was the newly described corynebacterium kroppenstedtii, followed by corynebacterium amycolatum and corynebacterium tuberculostearicum. gram-positive bacilli were seen in samples sent for culture or in histological specimens for 12 women, and 9 of the 12 women from whom adequate histological specimens were obtained had conditions that met the criteria for granulomatous lobular m ... | 2002 | 12439810 |
| a clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. | granulomatous mastitis is a rare condition of unknown aetiology. the great majority of cases has not been associated with bacterial pathogens if women with mammary tuberculosis are excluded. we noted that some women in auckland with a histological diagnosis of granulomatous mastitis had both microbiological and histological evidence of corynebacteria infection and aimed to study this further. | 2003 | 12745457 |
| isolations of corynebacterium kroppenstedtii from a breast abscess. | the recently described species corynebacterium kroppenstedtii was isolated from a breast abscess in a 38-year-old woman on two occasions. we discuss the pathogenic role of this bacteria and the methods used for its isolation. | 2004 | 15595392 |
| ultrafast pyrosequencing of corynebacterium kroppenstedtii dsm44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids. | corynebacterium kroppenstedtii is a lipophilic corynebacterial species that lacks in the cell envelope the characteristic alpha-alkyl-beta-hydroxy long-chain fatty acids, designated mycolic acids. we report here the bioinformatic analysis of genome data obtained by pyrosequencing of the type strain c. kroppenstedtii dsm44385 that was initially isolated from human sputum. a single run with the genome sequencer flx system revealed 560,248 shotgun reads with 110,018,974 detected bases that were ass ... | 2008 | 18430482 |
| first description of nod2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to corynebacteria. | we report the first case of granulomatous mastitis due to corynebacterium kroppenstedtii linked to strongly impaired neutrophil responses to nod2 agonist and a single nucleotide polymorphism within the nod2 gene (snp13 [leu1007fsinsc]) in a heterozygous state. these findings provided the first demonstration of impaired nod2 function associated with corynebacterial infection. | 2009 | 19641059 |
| treatment of otitis externa associated with corynebacterium kroppenstedtii in a peach-faced lovebird (agapornis roseicollis) with an acetic and boric acid commercial solution. | a 5-year-old lovebird (agapornis roseicollis) was presented with scaly crusts around both external ear openings and exudate present around the left ear. the bird had been treated with ivermectin and enrofloxacin without success. a pure culture of corynebacterium kroppenstedtii was isolated from both ears. after susceptibility testing, a treatment of an acetic and boric acid solution administered topically 3 times daily was prescribed. the scaly appearance disappeared after 14 days of treatment a ... | 2009 | 19673461 |
| clinical significance of commensal gram-positive rods routinely isolated from patient samples. | commensal bacteria from the skin and mucosal surfaces are routinely isolated from patient samples and considered contaminants. the majority of these isolates are catalase-positive gram-positive rods from multiple genera routinely classified as diphtheroids. these organisms can be seen upon gram staining of clinical specimens or can be isolated as the predominant or pure species in culture, raising a priori suspicion of a possible involvement in infection. with the development and adoption of mat ... | 2016 | 27629905 |
| characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis. | human infections associated with corynebacterium kroppenstedtii are rarely reported, and this organism is usually described as antibiotic sensitive. almost all published cases of c. kroppenstedtii infections have been associated with breast pathology in women and have been described in new zealand, france, canada, india and japan. here we describe the microbiologic characteristics of two strains isolated from two women diagnosed of granulomatous mastitis in spain. one c. kroppenstedtii isolate w ... | 2016 | 27818775 |
| clinical metagenomic analysis of bacterial communities in breast abscesses of granulomatous mastitis. | granulomatous mastitis (gm) is a chronic inflammatory breast lesion. its etiology remains incompletely defined. although mounting evidence suggests the involvement of corynebacterium in gm, there has been no systematic study of gm bacteriology using -omics technology. | 2016 | 27777091 |
| closing the brief case: recurrent granulomatous mastitis due to corynebacterium kroppenstedtii. | | 2016 | 27458276 |
| the brief case: recurrent granulomatous mastitis due to corynebacterium kroppenstedtii. | | 2016 | 27458268 |
| a microbiological and clinical review on corynebacterium kroppenstedtii. | the genus corynebacterium represents a taxon of gram-positive bacteria with a high g+c content in the genomic dna. corynebacterium kroppenstedtii is an unusual member of this taxon as it lacks the characteristic mycolic acids in the cell envelope. genome sequence analysis of the c. kroppenstedtii type strain has revealed a lipophilic (lipid-requiring) lifestyle and a remarkable repertoire of carbohydrate uptake and utilization systems. clinical isolates of c. kroppenstedtii have been obtained al ... | 2016 | 27155209 |
| early prosthetic valve endocarditis caused by corynebacterium kroppenstedtii. | corynebacterium (c.) kroppenstedtii is a rarely detected agent of bacterial infections in humans. here, we describe the first case of prosthetic valve endocarditis caused by c. kroppenstedtii. application of molecular methods using surgically excised valve tissue was a cornerstone for the establishment of the microbiological diagnosis, which is crucial for targeted antimicrobial treatment. | 2015 | 26560681 |
| two cases of granulomatous mastitis caused by corynebacterium kroppenstedtii infection in nulliparous young women with hyperprolactinemia. | recently, an association between granulomatous mastitis and local infection with corynebacterium (c.) kroppenstedtii has been suggested. we herein report two cases of granulomatous mastitis resulting from c. kroppenstedtii infection in nulliparous young women with hyperprolactinemia. both cases involved nulliparous patients with drug-induced hyperprolactinemia, and both individuals received incision and drainage, after which the pus was sent to our laboratory. corynebacterium spp. grew on blood ... | 2015 | 26179543 |
| recurrent corynebacterium kroppenstedtii breast abscess in a young asian female. | | 2015 | 26136183 |
| antimicrobial treatment options for granulomatous mastitis caused by corynebacterium species. | corynebacterium species are increasingly recognized as important pathogens in granulomatous mastitis. currently, there are no published treatment protocols for corynebacterium breast infections. this study describes antimicrobial treatment options in the context of other management strategies used for granulomatous mastitis. corynebacterium spp. isolated from breast tissue and aspirate samples stored from 2002 to 2013 were identified and determined to the species level using matrix-assisted lase ... | 2015 | 26135858 |
| draft genome sequences of corynebacterium kroppenstedtii cnm633/14 and cnm632/14, multidrug-resistant and antibiotic-sensitive isolates from nodules of granulomatous mastitis patients. | corynebacterium kroppenstedtii has been associated with infections of the female breast. genome sequencing of two strains revealed a specific genomic island in the multidrug-resistant isolate cnm633/14 with similarity to the r plasmid pja144188 of corynebacterium resistens dsm 45100, being indicative of the horizontal transfer of antibiotic resistance genes to c. kroppenstedtii. | 2015 | 25999560 |
| recurrent breast abscesses due to corynebacterium kroppenstedtii, a human pathogen uncommon in caucasian women. | background. corynebacterium kroppenstedtii (ck) was first described in 1998 from human sputum. contrary to what is observed in ethnic groups such as maori, ck is rarely isolated from breast abscesses and granulomatous mastitis in caucasian women. case presentation. we herein report a case of recurrent breast abscesses in a 46-year-old caucasian woman. conclusion. in the case of recurrent breast abscesses, even in caucasian women, the possible involvement of ck should be investigated. the current ... | 2012 | 23008788 |
| corynebacterium kroppenstedtii is an emerging cause of mastitis especially in patients with psychiatric illness on antipsychotic medication. | this retrospective study of patients with corynebacterium kroppenstedtii infections revealed a predominance of mastitis and a potential association with psychiatric illnesses. at least one third of our patients with c kroppenstedtii mastitis had psychiatric illness, and >92% received antipsychotic medications. drug-induced hyperprolactinemia may be an important modifiable risk factor in these patients. | 2017 | 28852671 |
| cystic neutrophilic granulomatous mastitis associated with corynebacterium including corynebacterium kroppenstedtii. | granulomatous (lobular) mastitis is a rare inflammatory breast disease affecting parous reproductive-aged women. once considered idiopathic, there is growing evidence of an association with corynebacteria infection, especially in the setting of a distinct histological pattern termed cystic neutrophilic granulomatous mastitis (cngm). we describe 15 cases with histological features either confirming (n = 12) or suggesting (n = 3) cngm, and concurrent microbiological evidence of corynebacterium spe ... | 2017 | 28442140 |