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nutritional evaluation of the seed proteins of calophyllum inophyllum, linn, and bassia latifolia. 19734763677
antibacterial principle of the root bark of calophyllum inophyllum: isolation and antibacterial activity. 19705423333
the piscicidal constituents of calophyllum inophyllum linn. 19685646801
triterpenes of calophyllum inophyllum linn. 19676047521
the inophyllums, novel inhibitors of hiv-1 reverse transcriptase isolated from the malaysian tree, calophyllum inophyllum linn.as part of a search for novel inhibitors of hiv-1 reverse transcriptase, the acetone extract of the giant african snail, achatina fulica, was shown to be active. fractionation of the extract yielded inophyllums a, b, c, and e and calophyllolide (1a, 2a, 3a, 3b, and 6), previously isolated from calophyllum inophyllum linn., a known source of nutrition for a. fulica. from a methanol/methylene chloride extract of c. inophyllum, the same natural products in considerably greater yield were isolated i ...19937506311
kinetic and mutational analysis of human immunodeficiency virus type 1 reverse transcriptase inhibition by inophyllums, a novel class of non-nucleoside inhibitors.inophyllums are novel non-nucleoside inhibitors of human immunodeficiency virus (hiv) type 1 reverse transcriptase identified through an enzyme screening program and isolated from the plant calophyllum inophyllum. the kinetics of reverse transcriptase inhibition by inophyllum b were characterized using recombinant purified enzyme, a heteropolymeric rna template, and a scintillation proximity assay. preincubation of inhibitor with the enzyme-template-primer complex for 11 min was required for max ...19947509800
anti-hiv coumarins from calophyllum seed oil.the seeds of calophyllum cerasiferum vesque (family-clusiaceae), and calophyllum inophyllum linn. (family-clusiaceae) contain several known coumarins, among which were the potent hiv reverse transcriptase inhibitors costatolide and inophyllum p. calophyllum cerasiferum contained (-)-calanolide b as its major coumarin constituent in significant amount and thus constitute a renewable source of this compound.19989934455
current lead natural products for the chemotherapy of human immunodeficiency virus (hiv) infection.a large variety of natural products have been described as anti-hiv agents, and for a portion thereof the target of interaction has been identified. cyanovirin-n, a 11-kda protein from cyanobacterium (blue-green alga) irreversibly inactivates hiv and also aborts cell-to-cell fusion and transmission of hiv, due to its high-affinity interaction with gp120. various sulfated polysaccharides extracted from seaweeds (i.e., nothogenia fastigiata, aghardhiella tenera) inhibit the virus adsorption proces ...200010934347
cancer chemopreventive agents, 4-phenylcoumarins from calophyllum inophyllum.in a search for anti-tumor-promoting agents, we carried out a primary screening of ten 4-phenylcoumarins isolated from calophyllum inophyllum l. (guttiferae), by examining their possible inhibitory effects on epstein--barr virus early antigen (ebv-ea) activation induced by 12-o-tetradecanoylphorbol-13-acetate in raji cells. all of the compounds tested in this study showed inhibitory activity against ebv, without showing any cytotoxicity. calocoumarin-a (5) showed more potent activity than any of ...200111410320
inocalophyllins a, b and their methyl esters from the seeds of calophyllum inophyllum.fractionation of the ethanolic extract of the seeds of calophyllum inophyllum l. has resulted in the isolation of four novel pyranocoumarin derivatives, designated as inocalophyllins a (1), b (2) and their methyl esters (3, 4) in addition to the known calophyllolide. the structures of these compounds have been determined on the basis of spectroscopic analysis including ms, heteronuclear single quantum coherence (hsqc), heteronuclear multiple bond connectivity (hmbc) and two dimensional incredibl ...200312843586
the in vitro evaluation of the antibacterial activity of undi oil (calophyllum inophyllum linn.). 195413201477
calophyllolide, a complex coumarin anticoagulant from calophyllum inophyllum linn. 196213862532
bioactivity of non-edible oil seed extracts and purified extracts against helicoverpa armigera (hubner).extracts and purified extracts of seeds of two plant species, madhuca latifolia and calophyllum inophyllum when evaluated against the 2nd instar larvae of helicoverpa armigera reared on synthetic diet, exhibited high larval mortality, prolongation of developmental period, morphological deformities and highly significant reduction in adult emergence. the reduction in larval weights in the treatments was also highly significant.200415274488
[effects of fungal elicitor on inophyllums production in suspension cultured cells of calophyllum inophyllum l].to investigate the effects of fungal elicitors on inophyllums production in suspension cultured cell of calophyllum inophyllum linn.200415303665
structures of new secofriedelane and friedelane acids from calophyllum inophyllum of french polynesia.three new friedelane-type triterpenoids, 3,4-secofriedelan-3,28-dioic acid (1), 27-hydroxyacetate canophyllic acid (2) and 3-oxo-27-hydroxyacetate friedelan-28-oic acid (3), were isolated from the leaves of calophyllum inophyllum (clusiaceae) grown in french polynesia. their structures were established by the concerted application of 2d nmr techniques including gs-cosy, gs-hmqc and gs-hmbc.200515468303
antimicrobial and cytotoxic agents from calophyllum inophyllum.the study of the chemical constituents of the root bark and the nut of calophyllum inophyllum has resulted in the isolation and characterization of a xanthone derivative, named inoxanthone, 3, together with 12 known compounds: caloxanthones a, 4 and b, 5, macluraxanthone, 6, 1,5-dihydroxyxanthone, 7, calophynic acid, 8, brasiliensic acid, 9 inophylloidic acid, 10, friedelan-3-one, 11, calaustralin, 12, calophyllolide, 13, inophyllums c, 14 and e, 15. their structures were established on the basi ...200415474565
allergic contact dermatitis from tamanu oil (calophyllum inophyllum, calophyllum tacamahaca). 200415500678
inhibitory effects of xanthones from guttiferae plants on paf-induced hypotension in mice.the inhibitory effects of 22 xanthones from three guttiferae plants (hypericum patulum, calophyllum inophyllum and c. austroindium) on exogenous platelet activating factor (paf)-induced hypotension were examined using a blood pressure monitoring in vivo assay method. guanandin (2), caloxanthone e (3), 1,3,5,6-tetrahydroxy-2-isoprenylxanthone (8), 6-deoxyjacareubin (11) and patulone (18) showed strong inhibition of paf-induced hypotension, with inhibitory effects of more than 60 %. their id50 val ...200515678383
composition of fatty acids triacylglycerols and unsaponifiable matter in calophyllum calaba l. oil from guadeloupe.the composition of the kernel oils of two calophyllum species (calophyllum calaba l. and calophyllum inophyllum l.) was investigated. the physico-chemical properties and fatty acid composition of the kernel oils were examined. in two species, oleic acid c18:1 (39.1-50%) is the dominating fatty acid followed by linoleic acid c18:2 (21.7-31.1%) as the second major fatty acid. stearic c18:0 (13.4-14.3%) and palmitic c16:0 (11-13.7%) acids are the major saturates. the oils contains an appreciable am ...200516045947
inophyllin a, a new pyranoxanthone from calophyllum inophyllum (guttiferae).in the authors' continuing search for new natural products, their recent studies on the roots of calophyllum inophyllum (guttiferae) have yielded a new prenylated pyranoxanthone, inophyllin a together with the common triterpenes friedelin and stigmasterol. structural elucidations of these compounds were achieved through (1)h, (13)c, dept, cosy, hsqc and hmbc experiments. the molecular mass was determined using ms techniques. the authors report here the isolation of and structural elucidation for ...200616644547
cytoprotective effect against uv-induced dna damage and oxidative stress: role of new biological uv filter.the majority of chemical solar filters are cytotoxic, particularly on sensitive ocular cells (corneal and conjunctival cells). consequently, a non-cytotoxic uv filter would be interesting in dermatology, but more especially in ophthalmology. in fact, light damage to the eye can be avoided thanks to a very efficient ocular antioxidant system; indeed, the chromophores absorb light and dissipate its energy. after middle age, a decrease in the production of antioxidants and antioxidative enzymes app ...200717188472
pattern of anti-hiv dipyranocoumarin expression in callus cultures of calophyllum inophyllum linn.callus cultures of calophyllum inophyllum were established using seed, nodal/ internodal and leaf explants on wpm basal medium supplemented with indole-3-butyric acid (iba), alpha-naphthalene acetic acid (naa), picloram (4-amino-3,5,6-trichloropicolinic acid), and 6-benzylaminopurine (bap) in different combinations and concentrations with the view to study the influence of hormones on callus induction and the pattern of expression of dipyranocoumarins including anti-hiv, non-nucleoside reverse t ...200717601621
[studies on flavonoids from stems and leaves of calophyllum inophyllum].to study the chemical constituents from the stems and leaves of calophyllum inophyllum.200717608221
tamanu (calophyllum inophyllum) - the african, asian, polynesian and pacific panacea.tamanu or calophyllum inophyllum has been used traditionally as a local medicine for many different purposes. the oil has been proven to be vulnerary and cicatrising in its effects. the chemicals responsible for this action are calophyllolide and inophyllum in addition to other complex polyphenols.200218494888
screening of anti-hiv-1 inophyllums by hplc-dad of calophyllum inophyllum leaf extracts from french polynesia islands.various pyranocoumarins, calophyllolide, inophyllums b, c, g(1), g(2) and p, from calophyllum inophyllum (clusiaceae) leaves of french polynesia (austral, marquesas, society and tuamotu archipelagos) have been determined in 136 leaf extracts using a high pressure liquid chromatography-uv-diode array detection (hplc-uv-dad) technique. results show a wide range in chemical composition within trees growing on eighteen islands. the use of multivariate statistical analyses (pca) shows geographical di ...200818706320
cytotoxic prenylated xanthones from calophyllum inophyllum.a new prenylated xanthone (1), named caloxanthone n, together with two known constituents, gerontoxanthone c (2) and 2-hydroxyxanthone (3), was isolated from the ethanolic extract of the twigs of calophyllum inophyllum. their structures were completely elucidated using a combination of 1d, 2d nmr techniques (cosy, hmqc, hmbc, and roesy) and hr-esi-ms analyses. compounds 1 and 2 exhibited cytotoxicity against chronic myelogenous leukemia cell line (k562) with ic50 values of 7.2 and 6.3 microg ml( ...200819003621
ocular burn: rinsing and healing with ionic marine solutions and vegetable oils.we investigated the effects of various rinsing and healing protocols on corneal wound repair and inflammation following alkali burn in rabbits.200919023222
[xanthones from leaves of calophyllum inophyllum linn].to study the xanthones from the leaves of calophyllum inophyllum linn., several chromatography methods were employed to isolate the constituents. investigation on the chcl3 extract led to the isolation of a new xanthone named inophyxanthone a (1) and four known compounds, which were pancixanthone a (2), gerontoxanthone b (3), jacareubin (4) and pyranojacareubin (5). among them, compound 2 was obtained from this plant firstly, and compound 3 was obtained for the first time from this genus. the st ...200919408685
biodiesel production and optimization from calophyllum inophyllum linn oil (honne oil)--a three stage method.the present work examines the production of a biodiesel from a non-edible oil namely honne oil (calophyllum inophyllum linn). a three stage process viz., pre-treatment, alkali catalyzed transesterification and post treatment adopted for the production is discussed. the reaction parameters such as methanol to oil molar ratio, catalyst concentration, temperature and time have been optimized for the production of biodiesel. the yield of biodiesel from the honne oil under the optimized conditions is ...200919505820
new tricyclic and tetracyclic pyranocoumarins with an unprecedented c-4 substituent. structure elucidation of tamanolide, tamanolide d and tamanolide p from calophyllum inophyllum of french polynesia.three new pyranocoumarin derivatives, tamanolide (1), tamanolide d (2) and tamanolide p (3), were isolated from the almond seeds of calophyllum inophyllum l. (clusiaceae) grown in french polynesia. these compounds, having an unprecedented c-4 isobutyl substituent, have been characterized as a new class of pyranocoumarins called tamanolides. their structures were elucidated on the basis of 1d and 2d nmr techniques (cosy, noesy, hsqc and hmbc) in association with ms (hr-esi-ms) data analysis.200919603395
systematic analysis of in vitro photo-cytotoxic activity in extracts from terrestrial plants in peninsula malaysia for photodynamic therapy.one hundred and fifty-five extracts from 93 terrestrial species of plants in peninsula malaysia were screened for in vitro photo-cytotoxic activity by means of a cell viability test using a human leukaemia cell-line hl60. these plants which can be classified into 43 plant families are diverse in their type of vegetation and their natural habitat in the wild, and may therefore harbour equally diverse metabolites with potential pharmaceutical properties. of these, 29 plants, namely three from each ...200919647445
equilibrium, thermodynamic and kinetic studies for the biosorption of aqueous lead(ii) ions onto the seed husk of calophyllum inophyllum.biosorption of lead(ii) ions from aqueous solution onto the seed husk of calophyllum inophyllum was investigated in a batch system. equilibrium, thermodynamics and kinetic studies were conducted by considering the effects of ph, initial metal ion concentration, contact time, and temperature. the results showed that the uptake of the metal ions increased with increase in initial metal ion concentration. the ph for optimum adsorption was 4 for the pb(ii) ions (q=4.86 mg/g and 97.2% adsorption). la ...201020083344
triterpenoids from calophyllum inophyllum and their growth inhibitory effects on human leukemia hl-60 cells.a new friedelane-type triterpene (1), along with seven known triterpenoids, was isolated from the stems and leaves of calophyllum inophyllum linn. their structures were established as 3beta, 23-epoxy-friedelan-28-oic acid (1), friedelin (2), epifriedelanol (3), canophyllal (4), canophyllol (5), canophyllic acid (6), 3-oxo-friedelan-28-oic acid (7), and oleanolic acid (8) by spectroscopic methods (nmr, ei-ms). the growth inhibitory effects of these triterpenoids on human leukemia hl-60 cells were ...201020188156
caloxanthones o and p: two new prenylated xanthones from calophyllum inophyllum.chemical investigation of the etoh extract of the twigs of calophyllum inophyllum collected in hainan province of china resulted in the isolation of two new prenylated xanthones, caloxanthone o (1) and caloxanthone p (2). their structures were elucidated by a study of their physical and spectral data. compound 1 exhibited cytotoxicity against human gastric cancer cell line (sgc-7901),with an ic50 value of 22.4 microg ml-1.201020335930
enhanced repellency of binary mixtures of zanthoxylum piperitum pericarp steam distillate or zanthoxylum armatum seed oil constituents and calophyllum inophyllum nut oil and their aerosols to stomoxys calcitrans.the repellency to stable fly, stomoxys calcitrans (l.), of zanthoxylum piperitum (l.) dc pericarp steam distillate (zp-sd), zanthoxylum armatum dc seed oil (za-so) and their constituents alone or in combination with calophyllum inophyllum l. nut oil (ci-no), as well as six aerosol formulations containing zp-sd or zp-so and ci-no, was compared with that of a synthetic repellent, deet, using an exposed human hand bioassay.201020628994
repellency to stomoxys calcitrans (diptera: muscidae) of plant essential oils alone or in combination with calophyllum inophyllum nut oil.the repellency to female stomoxys calcitrans (l.) (diptera: muscidae) of 21 essential oils (eos) alone or in combination with calophyllum inophyllum l. (clusiaceae) nut oil (tamanu oil) was examined using an exposed human hand bioassay. results were compared with those of commonly used repellent n,n-diethyl-3-methylbenzamide (deet). in tests with six human male volunteers at a dose of 0.5 mg/cm2, patchouli (protection time [pt], 3.67 h) was the most effective eo but less active than deet (4.47 h ...201020695272
two-step biodiesel production from calophyllum inophyllum oil: optimization of modified β-zeolite catalyzed pre-treatment.in this study, a two-step process was developed to produce biodiesel from calophyllum inophyllum oil. pre-treatment with phosphoric acid modified β-zeolite in acid catalyzed esterification process preceded by transesterification which was done using conventional alkali catalyst potassium hydroxide (koh). the objective of this study is to investigate the relationship between the reaction temperatures, reaction time and methanol to oil molar ratio in the pre-treatment step. central composite desig ...201120833536
ethnobotanical survey of medicinal plants commonly used by kani tribals in tirunelveli hills of western ghats, india.for thousands of years, medicinal plants have played an important role throughout the world in treating and preventing a variety of diseases. kani tribal people in tirunelveli hills still depend on medicinal plants and most of them have a general knowledge of medicinal plants which are used for first aid remedies, to treat cough, cold, fever, headache, poisonous bites and some simple ailments.201121291981
a new prenylated xanthone from the branches of calophyllum inophyllum.the investigation of chemical constituents from the branches of calophyllum inophyllum linn led to the isolation of a new prenylated xanthone, named caloxanthone q (1), together with three known compounds, 2-deprenylrheediaxanthone b (2), jacareubin (3), and 6-deoxyjacareubin (4). their structures were completely elucidated on the basis of spectroscopic methods (uv, ir, hr-esi-ms, 1d nmr, and 2d nmr).201121409690
a novel prenylated xanthone from the stems and leaves of calophyllum inophyllum.a novel prenylated xanthone, caloxanthone q (1), was isolated from the stems and leaves of calophyllum inophyllum. the structure elucidation was carried out by detailed spectroscopic analysis.201121547841
5-meth-oxy-2,2-dimethyl-6-[(2e)-2-methyl-but-2-eno-yl]-10-phenyl-2h,8h-pyrano[2,3-f]chromen-8-one (calophyllolide).the title compound, c(26)h(24)o(5), was isolated from calophyllum inophyllum seeds. in the mol-ecule, the phenyl and 2-methyl-but-2-enoyl groups are almost orthogonal to the chromene fragment [c-c-c-c torsion angles = 81.4 (3) and -90.1 (2)°, respectively]. in the crystal packing, centrosymmetrically related mol-ecules are linked by c-h⋯o contacts into dimers, which are connected via further c-h⋯o inter-actions into a double chain along [010].201021579166
a new furanoxanthone from the stem bark of calophyllum inophyllum.the stem bark extracts of calophyllum inophyllum furnished one new furanoxanthone, inophinnin (1), in addition to inophyllin a (2), macluraxanthone (3), pyranojacareubin (4), 4-hydroxyxanthone, friedelin, stigmasterol, and betulinic acid. the structures of these compounds were determined by spectroscopic analysis of 1d and 2d nmr spectral data ((1)h, (13)c, dept, cosy, hmqc, and hmbc) while ei-ms gave the molecular mass. the new xanthone, inophinnin (1), exhibited some anti-inflammatory activity ...201121972812
Microsatellite markers derived from Calophyllum inophyllum (Clusiaceae) expressed sequence tags.• Premise of the study: Robust markers are required (inter alia) for assessing origins of Calophyllum inophyllum populations on the Bonin Islands, Japan. Therefore, informative expressed sequence tag (EST)-based microsatellite or simple sequence repeat (SSRs) markers in the species were sought. • Methods and Results: Using 135378 ESTs derived from de novo pyrosequencing, primers for 475 EST-SSRs were developed, 48 of which were tested for PCR amplification. Thirty-six of the 48 primers showed cl ...201122203650
the wound healing and antibacterial activity of five ethnomedical calophyllum inophyllum oils: an alternative therapeutic strategy to treat infected wounds.calophyllum inophyllum l. (calophyllaceae) is an evergreen tree ethno-medically used along the seashores and islands of the indian and pacific oceans, especially in polynesia. oil extracted from the seeds is traditionally used topically to treat a wide range of skin injuries from burn, scar and infected wounds to skin diseases such as dermatosis, urticaria and eczema. however, very few scientific studies reported and quantified the therapeutic properties of calophyllum inophyllum oil (cio). in t ...201526406588
calophyllolide content in calophyllum inophyllum at different stages of maturity and its osteogenic activity.calophyllum inophyllum is a coastal plant rich in natural substances. its ingredients have been used for the development of an anti-human immunodeficiency virus (hiv) drug. in this study, we collected c. inophyllum fruit, and the ethanol extract of the fruit was chromatographically separated using silica gel and sephadex lh-20 columns to obtain the major compound, calophyllolide. the fruits were harvested from september to december in 2011; a quantitative analysis of the calophyllolide content w ...201526198219
coumarins as potential inhibitors of dna polymerases and reverse transcriptases. searching new antiretroviral and antitumoral drugs.human immunodeficiency virus (hiv) is the viral agent of acquired immunodeficiency syndrome (aids), and at present, there is no effective vaccine against hiv. reverse transcriptase (rt) is an essential enzyme for retroviral replication, such as hiv as well as for other rna infectious viruses like human t lymphocyte virus. polymerases act in dna metabolism, modulating different processes like mitosis, damage repair, transcription and replication. it has been widely documented that dna polymerases ...201526179474
biohydrogen and polyhydroxyalkanoate co-production by enterobacter aerogenes and rhodobacter sphaeroides from calophyllum inophyllum oil cake.the feasibility of coupled biohydrogen and polyhydroxyalkanoate production by enterobacter aerogenes and rhodobacter sphaeroides using calophyllum inophyllum oil cake was studied under dark and photo fermentation conditions. the utilization of a non-edible acidic oil cake (c. inophyllum), and exploitation of a modified minimal salt media led to reduction in the cost of media. cost of fermentation is reduced by implementation of alternate dark-photo fermentative periods and through the use of a c ...201424859207
antimicrobial assessment of resins from calophyllum antillanum and calophyllum inophyllum.the calophyllum genus is well-known for its antimicrobial and cytotoxic activities, and therefore, we analyzed these biological activities for resins of calophyllum antillanum and calophyllum inophyllum growing in cuba. c. antillanum resins showed a potent activity against plasmodium falciparum (ic50  = 0.3 ± 0.1 µg/ml), while its cytotoxicity against mrc-5 cells was much lower (ic50  = 21.6 ± 1.1 µg/ml). in contrary, the resin of c. inophyllum showed an unspecific activity. the presence of apet ...201526514875
biodiesel from plant seed oils as an alternate fuel for compression ignition engines-a review.the modern scenario reveals that the world is facing energy crisis due to the dwindling sources of fossil fuels. environment protection agencies are more concerned about the atmospheric pollution due to the burning of fossil fuels. alternative fuel research is getting augmented because of the above reasons. plant seed oils (vegetable oils) are cleaner, sustainable, and renewable. so, it can be the most suitable alternative fuel for compression ignition (ci) engines. this paper reviews the availa ...201627743330
ethnobotanical survey of cosmetic plants used in marquesas islands (french polynesia).cosmetic plants and their uses have often been neglected in ethnobotanical surveys which focus mainly on plants with medicinal or food uses. thus, this survey was carried out to specifically investigate cosmetics in a small community and to establish a cosmetopoeia, based on the model of pharmacopoeia for medicinal plants. the geographic spread of the survey covered the marquesas islands, one of the five archipelagos of french polynesia (pacific ocean). this archipelago was also recently investi ...201627899137
in vivo antiarthritic activity of the ethanol extracts of stem bark and seeds of calophyllum inophyllum in freund's complete adjuvant induced arthritis.calophyllum inophyllum linn. (clusiaceae) (ci) is traditionally used to treat pain, inflammation, eye disorders and rheumatism.201727593261
removal of basic violet 14 from aqueous solution using sulphuric acid activated materials.in this study the adsorption of basic violet, 14 from aqueous solution onto sulphuric acid activated materials prepared from calophyllum inophyllum (cs) and theobroma cacao (ts) shells were investigated. the experimental data were analysed by langmuir, freundlich and temkin isotherm models. the results showed that cs has a superior adsorption capacity compared to the ts. the adsorption capacity was found to be 1416.43 mg/g for cs and 980.39 mg/g for ts. the kinetic data results at different conc ...201627330899
biological activity of polynesian calophyllum inophyllum oil extract on human skin cells.oil from the nuts of calophyllum inophyllum, locally called "tamanu oil" in french polynesia, was traditionally used for wound healing and to cure various skin problems and ailments. the skin-active effect of "tamanu oil emulsion" was investigated on human skin cells (keratinocytes and dermal fibroblasts) and showed cell proliferation, glycosaminoglycan and collagen production, and wound healing activity. transcriptomic analysis of the treated cells revealed gene expression modulation including ...201627280931
utilization of calophyllum inophyllum shell and kernel oil cake for reducing sugar production.this study is aimed at fully utilizing fruit biomass of calophyllum inophyllum for reducing sugar production. the effects of pretreatment conditions and post reaction wash on the lignin removal and enzymatic hydrolysis of shell were investigated. the oil cake was also subjected to solvent extraction followed by enzymatic hydrolysis. the results showed that the sequential acid/alkaline pretreatment of c. inophyllum shell resulted in better delignification than alkaline or acid only pretreatment. ...201627130225
neurobehavioural activities of the ethanol leaf extract of calophyllum inophyllum in rodents.the present study was designed to investigate the central nervous system activities of the ethanol leaf extract of calophyllum inophyllum in rodents.201426223138
thermal and catalytic slow pyrolysis of calophyllum inophyllum fruit shell.pyrolysis of calophyllum inophyllum shell was performed in a fixed bed pyrolyser to produce pyrolytic oil. both thermal (without catalysts) and catalytic pyrolysis process were conducted to investigate the effect of catalysts on pyrolysis yield and pyrolysis oil characteristics. the yield of pyrolytic oil through thermal pyrolysis was maximum (41% wt) at 425 °c for particle size of 1.18 mm and heating rate of 40 °c/min. in catalytic pyrolysis the pyrolytic oil yield was maximum (45% wt) with bot ...201526162524
chemical compositions and termiticidal activities of the heartwood from calophyllum inophyllum l.wood extractives from heartwood of callophylum inophyllum (bintangor) were obtained by shaker method and analyzed for their constituents by gas chromatography-mass spectrometry (gc-ms). ten compounds were identified by ethanol (etoh) solvents, fourteen by methanol (meoh) and only nine by petroleum ether (petethr). major compounds were contributed by monoterpenes (75.11%, 53.75%) when extracted with etoh and petethr solvents. the anti-termitic assay of the wood extracts was also investigated agai ...201526131633
comparison of iso-eluotropic mobile phases at different temperatures for the separation of triacylglycerols in non-aqueous reversed phase liquid chromatography.triacylglycerols (tags) are a large class of neutral lipids that naturally occur in both plant and animal oils and fats. their analyses in non-aqueous reversed phase liquid chromatography (narp) require a mixture of weak solvent (mostly acetonitrile) and strong solvent. in the present work, we have established eluotropic solvent strength scale of several binary mobile phases on c18 bonded silica at different temperatures (acetonitrile/methylene chloride, acetonitrile/acetone, acetonitrile/ethyl ...201525855317
antiproliferative xanthone derivatives from calophyllum inophyllum and calophyllum soulattri.structure-activity relationships of eleven xanthones were comparatively predicted for four cancer cell lines after the compounds were subjected to antiproliferative assay against b-lymphocyte cells (raji), colon carcinoma cells (ls174t), human neuroblastoma cells (imr-32) and skin carcinoma cells (sk-mel-28). the eleven chemical constituents were obtained naturally from the stem bark of calophyllum inophyllum and calophyllum soulattri. inophinnin (1) and inophinone (2) were isolated from calophy ...201525730799
free fatty acid induced impairment of insulin signaling is prevented by the diastereomeric mixture of calophyllic acid and isocalophyllic acid in skeletal muscle cells.elevated fatty acid levels play a pathogenic role in the development of insulin resistance, associated with type 2 diabetes. interventions with ability to ameliorate fatty acid-induced insulin resistance might be useful for the management of diabetes. here, we explored the effect of the diastereomeric mixture of calophyllic acid and isocalophyllic acid (f015) on palmitate-induced insulin resistance in skeletal muscle cells. an incubation of l6 myotubes with palmitate inhibited insulin-stimulated ...201525445050
calophyllum inophyllum and calophyllum soulattri source of anti-proliferative xanthones and their structure-activity relationships.extensive chromatographic isolation and purification of the extracts of the stem bark of calophyllum inophyllum and calophyllum soulattri have resulted in 11 xanthones. c. inophyllum gave inophinnin (1), inophinone (2), pyranojacareubin (5), rheediaxanthone a (6), macluraxanthone (7) and 4-hydroxyxanthone (8), while c. soulattri afforded soulattrin (3), phylattrin (4), caloxanthone c (9), brasixanthone b (10) and trapezifolixanthone (11). the structures of these compounds were determined on the ...201525229947
enhanced repellency of binary mixtures of calophyllum inophyllum nut oil fatty acids or their esters and three terpenoids to stomoxys calcitrans.an assessment was made of the repellency to female stable flies of tamanu nut oil fatty acids or their esters alone (each 0.5 mg cm(-2) ) or in combination with cuminyl alcohol, cuminaldehyde and α-phellandrene (each 0.25 mg cm(-2) ), using an exposed human hand bioassay. results were compared with those of synthetic repellent deet (0.25 mg cm(-2) ).201525204729
diastereomeric mixture of calophyllic acid and isocalophyllic acid stimulates glucose uptake in skeletal muscle cells: involvement of pi-3-kinase- and erk1/2-dependent pathways.the diastereomeric mixture of calophyllic acid and isocalophyllic acid (f015) isolated from the leaves of calophyllum inophyllum was investigated for the metabolic effect on glucose transport in skeletal muscle cells. in l6 myotubes, f015 dose-dependently stimulated glucose uptake by increasing translocation of glucose transporter4 (glut4) to plasma membrane without affecting their gene expression. the effects on glucose uptake were additive to insulin. inhibitors analyses revealed that f015-ind ...201323428406
antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of calophyllum inophyllum.in continuation of our drug discovery program on indian medicinal plants, we isolated bioactive compounds (1-5) from the leaves of calophyllum inophyllum and evaluated their antidyslipidemic activity in triton induced hyperlipidemia model. the calophyllic acid (1a) and isocalophyllic acid (1b) mixture, canophyllic acid (4) and amentoflavone (5) showed dose dependent lipid lowering activity in in vivo experiments. the compounds 1a+1b mixture and 3 also showed good in vitro antioxidant activity.201223083817
phytostabilization of iron ore tailings through calophyllum inophyllum l.the phytostabilization of waste material generated during mining and processing of iron ore through calophyllum inophyllum l. have been investigated. iron ore tailings and its varying composition with garden soil were taken to study plant growth, chlorophyll content and metal uptake pattern of calophyllum inophyllum l. these studies indicate that 100% survival of plant species was noted in all the treatments without any toxicity symptoms. the increase in growth parameters and chlorophyll content ...201222908660
anti-inflammatory effects of calophyllum inophyllum l. in raw264.7 cells.calophyllum inophyllum l. has been used as folk medicine in the treatment of ocular burn and it has demonstrated potential to be an anti-inflammatory agent. the aim of this study was to explore the anti-inflammatory activities of an acetone extract of c. inophyllum l. leaves (cil). the cil extract was tested on lipopolysaccharide (lps)-induced raw 264.7 cells to evaluate the effect of cil extract on the expression of nitric oxide (no) and inducible nitric oxide synthase (inos). results showed th ...201222735972
the pyranoxanthone inophyllin a induces oxidative stress mediated-apoptosis in jurkat t lymphoblastic leukemia cells.inophyllin a (ino-a), a pyranoxanthone isolated from the roots of calophyllum inophyllum represents a new xanthone with potential chemotherapeutic activity. in this study, the molecular mechanism of ino-a-induced cell death was investigated in jurkat t lymphoblastic leukemia cells. assessment of phosphatidylserine exposure confirmed apoptosis as the primary mode of cell death in ino-a-treated jurkat cells. ino-a treatment for only 30 min resulted in a significant increase of tail moment which su ...201222613213
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