| antimalarial and cytotoxic depsidones from the fungus chaetomium brasiliense. | four new depsidones, mollicellins k-n (1-4), and six known depsidones, mollicellins b (5), c (6), e (7), f (8), h (9), and j (10), along with two known sterols were isolated from the fungus chaetomium brasiliense. their structures were elucidated on the basis of 1d and 2d nmr spectroscopic data and chemical transformation. among these isolates, 1-3, 5-7, and 10 exhibited antimalarial activity against plasmodium falciparum. only 1 exhibited antimycobacterial activity against mycobacterium tubercu ... | 2009 | 19663417 |
| phaeohyphomycosis and onychomycosis due to chaetomium spp., including the first report of chaetomium brasiliense infection. | chaetomium species have been rarely described as aetiological agents of invasive and dermatomycotic infections in humans. the majority of cases have been reported within the last two decades. treatment failed in most of these cases. in this paper we present two cases in which chaetomium spp. can be clearly identified as an aetiological agent in pathological conditions. in the first report, we describe a new aetiological agent, chaetomium brasiliense, which was implicated in a case of otitis exte ... | 2011 | 21466265 |