Publications

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[the active principles of litsea cubeba in the treatment of coronary heart disease]. 19852935312
[studies on the alkaloids of formosan lauraceous plants. v. alkaloids of litsea cubeba persoon]. 19655890303
[treatment of cerebral thrombosis with litsea cubeba (zour) pers]. 19846241535
[pharmacological studies on anti-asthmatic and anti-anaphylactic activities of the essential oil of litsea cubeba (lour.) pers. (author's transl)]. 19807257779
vasorelaxing effect in rat thoracic aorta caused by laurotetanine isolated from litsea cubeba persoon.the pharmacological effects of laurotetanine on rat isolated thoracic aorta were examined. the contraction of aortic rings caused by high potassium (60 mm) and cumulative concentrations of calcium (0.03-3 mm) was inhibited by 3-50 microm laurotetanine in a dose-dependent manner with an ic50 value of 19.8 +/- 3.6 microm (n = 6) in a 1 mm ca2+ medium. the phenylephrine (3 microm)-induced contraction was also inhibited by laurotetranine. its effect was more marked on the tonic contraction than on t ...19948083812
evaluation of massage with essential oils on childhood atopic eczema.childhood atopic eczema is an increasingly common condition in young children. as well as being irritating to the child, it causes sleepless nights for both the child and the family and leads to difficulties in parental relationships and can have severe effects on employment. a group of eight children, born to professional working mothers were studied to test the hypothesis that massage with essential oils (aromatherapy) used as a complementary therapy in conjunction with normal medical treatmen ...200010960901
report by the analytical methods committee. application of gas-liquid chromatography to the analysis of essential oils. part xviii. determination of safrole in oils of cinnamon leaf, litsea cubeba, and nutmeg. 200211996373
[chemical composition of essential oil from leaves of litsea cubeba and its antifungal activities].the 24 chemical constituents of the essential oil extracted from the leaves of litsea cubeba have been identified by means of gc-ms technique. among which, alpha-cis-ocimene(25.11%), 3,7-dimethyl-1,6-octadien-3-ol(16.85%) and n-transnerolidol (13.89%) were the principal components. in vitro this oil had a manifest antifungal activities with mic between 0.03-0.4 microliter/ml for utilized pathogenic fungi and 1.0-2.0 microliters/ml for moulds.199912571886
effects of citral on aspergillus flavus spores by quasi-elastic light scattering and multiplex microanalysis techniques.citral refined from litsea cubeba oil has been found to have a strong influence on fungi, especially aspergillus flavus. multiplex microanalysis and quasi-elastic light scattering techniques were applied to study the effects of citral on aspergillus flavus spores from the levels of membrane, organelle and intracellular macromolecule. it was found that citral injured the wall and the membrane of a. flavus spore, resulting in decrease of its elasticity. after entering the cell, citral not only inf ...200415253153
acute and genetic toxicity of essential oil extracted from litsea cubeba (lour.) pers.litsea cubeba oil is an aromatic essential oil extracted from the fresh fruits of litsea cubeba (lour.) pers. it is used as a flavor enhancer in foods, cosmetics, and cigarettes; as a raw material in the manufacture of citral, vitamins a, e, and k, ionone, methyl ionone, and perfumes; and as an antimicrobial and insecticide. based on the widespread use of l. cubeba oil, its insolubility in water, resulting in its partition in soil sediment, and its volatility when exposed to the atmosphere, risk ...200515771186
the sensilla of aedes and anopheles mosquitoes and their importance in repellency.the aim of this study was to detect the role of some mosquito organs in their sensation of repellent materials. a total of 250 females (15 days old) of the target species aedes aegypti and anopheles stephensi were prepared and divided into five groups: group 1, without antenna; group 2, without maxillary bulbs; group 3, without proboscis; group 4, without frontal tarsus; and group 5, normal females as control. a mixture of five oils containing litsea cubeba 1%, melaleuca leucadendron 1%, melaleu ...200616642383
repellency effect of forty-one essential oils against aedes, anopheles, and culex mosquitoes.since ancient times, plant products were used in various aspects. however, their use against pests decreased when chemical products became developed. recently, concerns increased with respect to public health and environmental security requiring detection of natural products that may be used against insect pests. in this study, 41 plant extracts and 11 oil mixtures were evaluated against the yellow fever mosquito, aedes aegypti (linnaeus), the malaria vector, anopheles stephensi (liston), and th ...200616642384
repellent activity of essential oils against cockroaches (dictyoptera: blattidae, blattellidae, and blaberidae) in thailand.seven commercial essential oils extracted from the plant species boesenbergia rotunda (l.) mansf., citrus hystrix dc., curcuma longa l., litsea cubeba (lour.) pers., piper nigrum l., psidium guajava l. and zingiber officinale roscoe, and naphthalene as a control, were evaluated for repellent activity against the three cockroach species periplaneta americana (l.), blattella germanica (l.) and neostylopyga rhombifolia (stoll) under laboratory conditions. the essential oil derived from citrus hystr ...200717883004
litebamine, a phenanthrene alkaloid from the wood of litsea cubeba, inhibits rat smooth muscle cell adhesion and migration on collagen.smooth muscle cells (smcs) play an important role in the development of atherosclerosis and restenosis after angioplasty and coronary bypass grafting. the pathogenesis of these vascular diseases includes the abnormal production of extracellular matrix (ecm) proteins by smcs and their interactions with this newly synthesized and preexisting ecm. litebamine, a natural phenanthrene alkaloid from the wood of litsea cubeba, has been shown to inhibit platelet aggregation and thromboxane b(2) formation ...200818773889
antimicrobially active isoquinoline alkaloids from litsea cubeba.bioassay-guided fractionation of the alkaloidal extract of the aerial part of litsea cubeba led to the isolation of two new isoquinoline alkaloids, (+)- n-(methoxycarbonyl)-n-norboldine (1) and (+)-isoboldine beta-n-oxide (2), together with 11 known analogues (3-13). their structures were established by extensive spectroscopic techniques and by comparing spectroscopic data with those in the literature. compounds 1 and 4 showed antimicrobial activities. this is the first report on the presence of ...200918991207
nematicidal activity of plant essential oils and components from ajowan (trachyspermum ammi), allspice (pimenta dioica) and litsea (litsea cubeba) essential oils against pine wood nematode (bursaphelenchus xylophilus).commercial plant essential oils from 26 plant species were tested for their nematicidal activities against the pinewood nematode, bursaphelenchus xylophilus. good nematicidal activity against b. xylophilus was achieved with essential oils of ajowan (trachyspermum ammi), allspice (pimenta dioica) and litsea (litsea cubeba). analysis by gas chromatography-mass spectrometry led to identification of 12, 6 and 16 major compounds from ajowan, allspice and litsea oils, respectively. these compounds fro ...200719259498
fumigant antitermitic activity of plant essential oils and components from ajowan ( trachyspermum ammi ), allspice ( pimenta dioica ), caraway ( carum carvi ), dill ( anethum graveolens ), geranium ( pelargonium graveolens ), and litsea ( litsea cubeba ) oils against japanese termite ( reticulitermes speratus kolbe).plant essential oils from 26 plant species were tested for their insecticidal activities against the japanese termite, reticulitermes speratus kolbe, using a fumigation bioassay. responses varied with source, exposure time, and concentration. among the essential oils tested, strong insecticidal activity was observed with the essential oils of ajowan ( trachyspermum ammi ), allspice ( pimenta dioica ), caraway ( carum carvi ), dill ( anethum graveolens ), geranium ( pelargonium graveolens ), and ...200919722567
compositions and in vitro anticancer activities of the leaf and fruit oils of litsea cubeba from taiwan.the leaf and fruit essential oils of litsea cubeba, extracted by hydrodistillation, were assessed for anticancer activities. a total of 53 and 50 compounds were identified, respectively from the leaf and fruit oils, and their yields were 13.9 +/- 0.09% and 4.0 +/- 0.03%, v/w, of the oven-dried materials, respectively. the main compound in the leaf oil was 1,8-cineol, and in the fruit oil, citral. the fruit oil, but not that of the leaf, exhibited cytotoxic activity against human lung, liver and ...201020433084
phototoxicity of essential oils intended for cosmetic use.the aim of this study, linked-up with a previous study on bergamot oils, was the evaluation of phototoxic potential of essential oils (orange, lemon and litsea cubeba), used as cosmetic ingredients. the applied tiered testing strategy included chemical analysis of the substances (by means of capillary gas chromatography/mass spectrometry), in vitro 3t3 nru phototoxicity test and epiderm™ skin phototoxicity test. in order to clarify the situation in man, the highest non-phototoxic/non-cytotoxic c ...201020688147
the fungicidal terpenoids and essential oil from litsea cubeba in tibet.a new c₉ monoterpenoid acid (litseacubebic acid, 1) and a known monoterpene lactone (6r)-3,7-dimethyl-7-hydroxy-2-octen-6-olide (2), along with three known compounds--vanillic acid (3), trans-3,4,5-trimethoxylcinnamyl alcohol (4), and oxonantenine (5)--were isolated with bioassay-guided purification from the fruit extract of litsea cubeba collected in tibet. the structure of 1 was elucidated by ms, ¹h-nmr, ¹³c-nmr, cosy, hsqc, hmbc, noe spectral data as 2,6-dimethyl-6-hydroxy-2e,4e-hepta-2,4-die ...201020944522
antibacterial activity of litsea cubeba (lauraceae, may chang) and its effects on the biological response of common carp cyprinus carpio challenged with aeromonas hydrophila.the aims of this study were to characterize the antibacterial activity and the chemotype of litsea cubeba leaf essential oil (eo) harvested in north vietnam and to investigate the biological effects induced by the leaf powder on growth, nonspecific immunity and survival of common carp (cyprinus carpio) challenged with aeromonas hydrophila.201627124660
stonebrood and chalkbrood in apis mellifera causing fungi: in vitro sensitivity to some essential oils.aim of the present study was to evaluate the in vitro antimycotic activity of 17 chemically defined essential oils (eos) both alone and as a mixture, against agents responsible for stonebrood caused by aspergillus flavus, and chalkbrood caused by ascosphaera apis in european honeybees. cinnamomum zeylanicum yielded the lowest mic value against a. flavus, but was not effective against a. apis, while litsea cubeba and pelargonium graveolens appeared to be effective against all checked fungi. asper ...201728326846
improvement of the antifungal activity of litsea cubeba vapor by using a helium-neon (he-ne) laser against aspergillus flavus on brown rice snack bars.the aim of this study was to improve the antifungal activity of the volatile litsea cubeba essential oil and its main components (citral and limonene) on brown rice snack bars by applying he-ne laser treatment. different volumes (50-200 μl) of l. cubeba, citral or limonene were absorbed into a filter paper and placed inside an oven (18 l). ten brown rice snack bars (2 cm wide × 4 cm long × 0.5 cm deep) were put in an oven and heated at 180 °c for 20 min. the shelf-life of the treated snack bars ...201526433461
antibacterial activity and kinetics of litsea cubeba oil on escherichia coli.litsea cubeba oil is extracted from the fresh fruits of litsea cubeba by distillation. in this study, its chemical constituents, antibacterial activity, kinetics and effects against escherichia coli were studied. its minimum inhibitory concentration (mic) and minimum bactericidal concentration (mbc) were both 0.125% (v/v) by toxic food method. moreover, the antibacterial kinetic curves indicated 0.0625% (v/v) of litsea cubeba oil was able to prolong the growth lag phase of e. coli cells to appro ...201425372706
antimicrobial impact of the components of essential oil of litsea cubeba from taiwan and antimicrobial activity of the oil in food systems.using natural additives to preserve foods has become popular due to consumer demands for nature and safety. antimicrobial activity is one of the most important properties in many plant essential oils (eos). the antimicrobial activity of the essential oil of litsea cubeba (lc-eo) from taiwan and the antimicrobial impact of individual volatile components in the oil on pathogens or spoilage microorganisms: vibrio parahaemolyticus, listeria monocytogenes, lactobacillus plantarum, and hansenula anoma ...201222459760
in vitro activity of twenty commercially available, plant-derived essential oils against selected dermatophyte species.the in vitro activity of twenty chemically defined essential oils (eos) obtained from boswellia sacra, citrus bergamia, c. limon, c. medica, cinnamomum zeylanicum, eucalyptus globulus, foeniculum vulgare, helichrysum italicum, illicium verum, litsea cubeba, mentha spicata, myrtus communis, ocimum basilicum, origanum majorana, o. vulgare, pelargonium graveolens, rosmarinus officinalis, santalum album, satureja montana, and thymus serpyllum was assayed against clinical animal isolates of microspor ...201526434145
susceptibility of microsporum canis arthrospores to a mixture of chemically defined essential oils: a perspective for environmental decontamination.the zoophilic dermatophyte microsporum canis has cats as natural reservoir, but it is able to infect a wide range of hosts, including humans, where different clinical features of the so-called ringworm dermatophytosis have been described. human infections are increasingly been reported in mediterranean countries. a reliable control program against m. canis infection in cats should include an antifungal treatment of both the infected animals and their living environment. in this article, a herbal ...201525854840
chemotype of litsea cubeba essential oil and its bioactivity.the essential oils from different parts of litsea cubeba, collected from the highlands of sarawak, were isolated and their chemical compositions analyzed. this study demonstrated significant variations in the chemical compositions and the chemical profiles of the volatiles and could provide valuable supplementary information on the geographical variations of the species. the fruit essential oil was dominated by citronellal, d-limonene and citronellol, while the leaf oil was high in eucalyptol an ...201526411035
synergistic repellent and irritant effect of combined essential oils on aedes aegypti (l.) mosquitoes.this study was designed to compare the behavioral responses of aedes aegypti to a single essential oil and to a mixture of two or three essential oils using an excito-repellency test chamber. mixtures were prepared from essential oils extracted from litsea cubeba (lc), litsea salicifolia (ls), and melaleuca leucadendron (ml). in general, the mixture of essential oils produced a much stronger escape response by ae. aegypti, regardless of the test conditions. no significant difference in escape re ...201425424258
excito-repellency properties of essential oils from melaleuca leucadendron l., litsea cubeba (lour.) persoon, and litsea salicifolia (nees) on aedes aegypti (l.) mosquitoes.we compared the behavioral responses of aedes aegypti females to essential oils extracted from native plants melaleuca leucadendron (ml), litsea cubeba (lc), and litsea salicifolia (ls) by using an excito-repellency test chamber. mortality of ae. aegypti females following 24 h holding period post-contact and non-contact trials were observed. no mortality was seen in escaped mosquitoes after direct contact with essential oils ml and ls, and low mortality (2.3-20.4%) with lc. likewise, in all non- ...200819263850
fumigant, contact, and repellent activities of essential oils against the darkling beetle, alphitobius diaperinus.the fumigant, contact, and repellent activities of four essential oils extracted from citrus limonum (sapindales: rutaceae), litsea cubeba (laurales: lauraceae), cinnamomum cassia, and allium sativum l. (asparagales: alliaceae) against 6th instars and adults of the darkling beetle, alphitobius diaperinus (panzer) (coleoptera: tenebrionidae), one of the main pests of materials and products of juncus effuses l. (poales: juncaceae) during the storage period, were assayed, and chemical ingredients w ...201425373222
authenticity control of essential oils containing citronellal and citral by chiral and stable-isotope gas-chromatographic analysis.enantioselective capillary gc on a supelco beta-dex 225 column (heptakis(2,3-di-o-acetyl-6-o-tert-butyldimethylsilyl)-beta-cyclodextrin spb 20poly--20% diphenyl, 80% dimethylsiloxane) and isotope-ratio mass spectrometry, coupled online with capillary gc on an hp5 column have been used for origin-specific analysis and authenticity control of essential oils, for example lemon (citrus limon), lemongrass (cymbopogon citratus and cymbopogon flexuosus), citronella (cymbopogon nardus l.--ceylon type an ...200617089103
the effect of chemical composition and bioactivity of several essential oils on tenebrio molitor (coleoptera: tenebrionidae).the major chemical components of four essential oils (eos) extracted from dry leaves of citrus limonum, cymbopogon citratus, litsea cubeba, and muristica fragrans were analyzed with gas chromatograph-mass spectrometer and their fumigant, contact, and repellent activities against 10th instar and adults of tenebrio molitor were also assayed. the results indicated that the major constituents of c. limonum and cy. citrates were d-limonene (38.22%) and 3,7-dimethyl-6-octenal (26.21%), while which of ...201526254287
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