| histoplasmosis due to histoplasma capsulatum var duboisii in a canadian immigrant. | histoplasmosis due to histoplasma capsulatum var duboisii developed in a canadian immigrant one year after his entry into canada. he had lived in guinea for two years prior to immigration. lymphatic infection characterized the course of his illness. the clinical and pathologic features of this disease's distinctive skin and bone manifestations are outlined. the causal agent's mycologic features are compared with those of h capsulatum var capsulatum. treatment with amphotericin b was successful. | 1978 | 646378 |
| tropical mycoses. | the most common tropical subcutaneous and deep mycoses include chromomycosis, sporotrichosis and mycetoma. all are commonly found in natal and in other subtropical countries. although blastomycosis is endemic in north america, only 4 cases have been identified in natal during the last 25 years, and all presented with atypical clinical features. african histoplasmosis, caused by histoplasma capsulatum var. duboisii and limited mainly to central and western africa, has been found in only 1 patient ... | 1992 | 1319312 |
| in vitro antifungal spectrum of itraconazole and treatment of systemic mycoses with old and new antimycotic agents. | itraconazole is a lipophilic triazole with potent in vitro activity. it is also effective after topical, oral and parenteral administration. the antifungal activity of itraconazole has been evaluated against more than 6,500 different strains, belonging to more than 260 fungal species, using the serial decimal dilution test in fluid broth medium (brain-heart infusion broth). candida spp., torulopsis spp., cryptococcus neoformans, pityrosporum spp. (dixon broth), various other yeasts, dermatophyte ... | 1992 | 1319313 |
| comparative evaluation of a chemiluminescent dna probe and an exoantigen test for rapid identification of histoplasma capsulatum. | a chemiluminescent dna probe (accuprobe) assay developed by gen probe, inc., for the rapid identification of histoplasma capsulatum was evaluated and compared with the exoantigen test by using 162 coded cultures including histoplasma capsulatum var. capsulatum, histoplasma capsulatum var. duboisii, histoplasma capsulatum var. farciminosum, blastomyces dermatitidis, coccidioides immitis, paracoccidioides brasiliensis, and morphologically related saprobic fungi. each test uses a chemiluminescent, ... | 1992 | 1452692 |
| an epizootic of histoplasmosis duboisii (african histoplasmosis) in an american baboon colony. | histoplasmosis duboisii, a chronic granulomatous disease caused by histoplasma capsulatum var. duboisii, was diagnosed in 21 baboons at a large primate colony in san antonio, texas. diagnosis was based on finding 8 to 15 microns-diameter yeast cells in histologic sections. therapy with drugs was unsuccessful. surgical removal of lesions was the primary treatment. epidemiologic data suggest the incubation period to be at least 9 months. the most likely route of infection was oral and happened dur ... | 1991 | 1666137 |
| production of extracellular collagenolytic proteinases by histoplasma capsulatum var. duboisii and histoplasma capsulatum var. capsulatum in the yeast phase. | yeast cultures of histoplasma capsulatum var. duboisii and h. capsulatum var. capsulatum in collagen containing defined, semi-defined and complex media produced extracellular collagenolytic proteinases, assayed using 4-phenylazo-benzyloxycarbonyl-l-propyl-l-leucyl- glycyl-l-propyl-d-arginine, a specific collagenase substrate. significant levels of hydroxyproline were measured in the cultures and clear zones of hydrolysis were produced in collagen buffer agar by the crude enzyme preparations. hyd ... | 1991 | 1668620 |
| in vitro production of extracellular elastolytic proteinase by histoplasma capsulatum var. duboisii and histoplasma capsulatum var. capsulatum in the yeast phase. | extracellular elastolytic proteinase was produced by yeast cultures of histoplasma capsulatum var. duboisii and h. capsulatum var. capsulatum in three different induction media, assayed using elastin-orcein as the substrate. medium-dependent variations in the time-course for enzyme production were observed and no peak was recorded. the proteinases hydrolysed both casein and bovine serum albumin indicating a broad substrate specificity. both elastolytic proteinases had similar optimum ph (ph 8) a ... | 1991 | 1824415 |
| [the use of exoantigens for identifying histoplasma capsulatum]. | the exoantigen test has been successfully used in the last years for the immunological identification of pathogenic fungi. twenty seven straing presumptively identified as histoplasma capsulatum by morphologic methods, were studied by such test. the exoantigens obtained from each strain were studied by immunoprecipitation technique in front of histoplasmosis control sera experimentally obtained in rabbits. reference strains of histoplasma capsulatum. histoplasma duboisii and paracoccidioides bra ... | 1990 | 2089510 |
| histoplasmosis duboisii (african histoplasmosis). an african case reported from chile with ultrastructural study. | a case of histoplasmosis duboisii in a 30 year-old engineer is presented. the diagnosis was made with the help of light microscopy, electron microscopy and cultures. although diagnosed in chile, the patient probably acquired the disease in the endemic african area, more precisely in the ivory coast. differential diagnosis between histoplasma capsulatum var. capsulatum and histoplasma capsulatum var. duboisii is based primarily on the larger in-vivo yeast form size of the latter. electron microsc ... | 1990 | 2247379 |
| african histoplasmosis masquerading as carcinoma of the colon. report of a case and review of literature. | a case of african histoplasmosis primarily affecting the large bowel--a very unusual manifestation--is reported. in the absence of classical clinical features, pathognomonic of large bowel histoplasmosis, the macroscopic appearance at surgery was confused with large-bowel cancer. the diagnosis was, therefore, retrospective and based on demonstration of large yeast cells of histoplasma capsulatum var. duboisii in tissue sections of the lesions. | 1989 | 2676427 |
| early experience with itraconazole in vitro and in patients: pharmacokinetic studies and clinical results. | the efficacy of itraconazole, a new triazole antifungal agent, was studied in vitro and assessed in patients. the mics of itraconazole for 16 strains of aspergillus fumigatus were in the same range as those of amphotericin b: less than 0.09-0.36 microgram/ml vs. less than 0.09-0.78 microgram/ml, respectively. eight adult patients with systemic fungal infections were treated orally with 100-200 mg of itraconazole two times a day. a patient with relapsing histoplasmosis (histoplasma capsulatum var ... | 1987 | 3027850 |
| case of disseminated african histoplasmosis in a baboon. | an adult red baboon (papio cynocephalus papio) had a severe disseminated case of african histoplasmosis (histoplasma capsulatum var. duboisii) with skin lesions from small pustules to ulcerative granulomas. osteolytic lesions were seen radiographically. treatment with ketoconazole for 6 months was unsuccessful. | 1988 | 3184166 |
| orbital histoplasmosis due to histoplasma capsulatum var. duboisii: successful treatment with septrin. | four children with orbital histoplasmosis caused by histoplasma capsulatum var. duboisii (one of whom had been unsuccessfully treated with amphotericin-b) were treated with a combination of trimethoprim and sulphamethoxazole (septrin) and surgical drainage. all patients improved markedly during therapy with resolution of the lesions, and with no recurrence of infection in three patients, 1 year later. the fourth patient was lost to follow-up. treatment was devoid of side effects. these findings ... | 1986 | 3491220 |
| [a case of histoplasmosis caused by histoplasma duboisii and treated by ketoconazole in bangui (c.a.r.)]. | the authors report on one case of histoplasmosis in a young girl aged of 12, showing about 200 ulcerous vegetative lesions distributed on her body. several different therapies were used without success. utilization of ketoconazole during 187 days lead to a very favourable course. but the patient, escaping from medical control, died 5 months later. existence of an acquired immunodeficient was supposed. | 1986 | 3773688 |
| immunological response of guinea pigs experimentally infected with histoplasma duboisii. | | 1974 | 4207173 |
| chemical and immunological properties of galactomannans obtained from histoplasma duboisii, histoplasma capsulatum, paracoccidioides brasiliensis and blasomyces dermatitidis. | | 1974 | 4279334 |
| biochemical characterization and skin test sensitivity of mycelial growth filtrate of histoplasma duboisii. | | 1972 | 4621377 |
| development and use of a polyvalent conjugate to differentiate histoplasma capsulatum and histoplasma duboisii from other pathogens. | previous investigations have demonstrated the existence of five histoplasma capsulatum serotypes. available specific fluorescent-antibody reagents stain only four of the five serotypes. antibodies produced against the most complete h. capsulatum serotype were labeled with fluorescein isothiocyanate to develop a reagent specific for h. capsulatum that was reactive with all the known serotypes. the unadsorbed reagent not only stained all the h. capsulatum serotypes, but it also stained cultures of ... | 1968 | 4869210 |
| cell wall composition and serological reactivity of histoplasma capsulatum serotypes and related species. | the composition of the cell walls of strains of histoplasma capsulatum that were reactive in the complement-fixation test and that reacted with fluorescein-tagged specific anti-h. capsulatum serum were compared with the cell walls of h. capsulatum and histoplasma duboisii that did not react in these serological tests. the cell walls of the serologically reactive strains of h. capsulatum were much more susceptible to the action of proteinases and to chitinase than were the serologically nonreacti ... | 1968 | 4895053 |
| a comparative morphological study of the yeast phases of histoplasma capsulatum and histoplasma duboisii. | | 1964 | 5874139 |
| chronic mucocutaneous candidosis and other superficial and systemic mycoses successfully treated with ketoconazole. | four patients with chronic mucocutaneous candidosis from early infancy were treated successfully with ketoconazole given orally. all thrush lesions were clinically and mycologically cured within a few days of treatment with 100-400 micrograms of ketoconazole daily; skin lesions were cured within a few weeks, and nails were cured after about three months of treatment. delayed cutaneous hypersensitivity to candidin was acquired by the third month. cellular and humoral immunologic responses were re ... | 1980 | 6255540 |
| laboratory and clinical assessment of ketoconazole in deep-seated mycoses. | forty-eight cases of deep mycoses were studied and treated with ketoconazole, each with in vitro evaluation of the minimum inhibitory concentrations (mic) of the causative fungi, in vivo pharmacokinetic, clinical, and mycologic evaluations, several months to two years after the treatment was stopped. excellent results were obtained in six cases of chronic mucocutaneous candidiasis, with restoration of immunologic disturbances; 23 cases of systemic candidiasis, including new aspects of heroin add ... | 1983 | 6295150 |
| [digestive disorders in histoplasmosis. report of a case of ulcerous enterocolitis caused by histoplasma capsulatum (author's transl)]. | report of a new american histoplasmosis caused by histoplasma capsulatum in a young adult haitian, and review of the digestive disorders as reported in the previous medical papers. in the present case, the first localization detected was a granulomatous hepatitis which lead to the disclosure of an ulcerous entercolitis. tuberculosis and crohn disease were first suspected, but their treatment induced a worse turn of the patient's condition and compelled to a laparotomy, which shown ulcerous enter ... | 1981 | 6972477 |
| [existence of histoplasma duboisii histoplasmosis outside continental africa (apropos of the first madagascar case)]. | the authors report a case of histoplasmosis with h. duboisii authenticated by an histopathologic examination, serology on cross-section. the patient, a 22 year old man from comorian ascent had never left madagascar and was working on a sugar-cane plantation. he was carrier of ulcerated and suppurated lesions in the inguinal folds and the ombilic and was to die without having received a proper treatment. it is the first case of great form histoplasmosis noticed in madagascar, outside continental ... | 1982 | 7172359 |
| [african histoplasmosis due to histoplasma capsulatum var. duboisii: relationship with aids in recent congolese cases]. | six new cases are described for african histoplasmosis, histoplasma capsulatum var. duboisii, from congo. the first was an hiv sero-negative child who has been monitored for the last three years. while under treatment with ketoconazole, amphotericin b, and finally itraconazole, the development of the infection was accompanied by purulent lesions, mainly cutaneous, but also superficial and deep lymphadenopathies. as a last option, itraconazole gave very satisfactory results both during the acute ... | 1995 | 7582643 |
| histoplasmosis capsulati and duboisii in europe: the impact of the hiv pandemic, travel and immigration. | the present report describes a fatal case of imported aids-related disseminated histoplasmosis capsulati infection associated with multiple coexisting infections, diagnosed with cultural recovery of histoplasma capsulatum var. capsulatum with a commercial radiometric mycobacterium medium. the epidemiological and clinical features of histoplasmosis capsulati and duboisii in europe are reviewed by examining also 69 documented cases of histoplasma capsulatum var. capsulatum infection (25 in aids pa ... | 1994 | 7672046 |
| a natural focus of histoplasma capsulatum var. duboisii is a bat cave. | the natural reservoir of histoplasma capsulatum var. duboisii, the etiological agent of histoplasmosis duboisii (african histoplasmosis) is not yet known. we report the isolation of h. capsulatum var. duboisii from soil admixed with bat guano and from the intestinal contents of a bat in a sandstone cave in a rural area, ogbunike in anambra state of nigeria. eight of 45 samples of soil admixed with bat guano yielded h. capsulatum var. duboisii. of the 35 bats belonging to the species nycteris his ... | 1994 | 7808510 |
| phylogeny of dermatophytes and dimorphic fungi based on large subunit ribosomal rna sequence comparisons. | the phylogeny of dermatophytes and dimorphic fungi was considered using the large-subunit of ribosomal rna (25s rrna). aligned sequences of 595 nucleotides covering the two most divergent domains d1 and d2, permitted a comparison of phylogenetic relationships at different levels. the dimorphic species (onygenaceae) were significantly separated from dermatophytes (arthrodermataceae) and from a third group including geophilic or very weakly pathogenic species (onygenaceae and gymnoascaceae). on a ... | 1994 | 7844699 |
| [bone and joint sites of african histoplasmosis (histoplasma duboisii). apropos of a case and review of the literature]. | the authors report a case of disseminated african histoplasmosis with bone and joint involvement in a black 28-year-old citizen of the central african republic who presented with a 17-month history of multiple osteoarticular lesions (sternoclavicular joints, humerus, ribs), cutaneous lesions (face, scalp, thorax), and lymphadenopathy. clinical manifestations resolved rapidly under treatment with ketoconazole (600 mg/d for 10 days then 400 mg/day for nine months). persistent yeast cells were then ... | 1994 | 7858578 |
| [african histoplasmosis in a patient with hiv-2 infection]. | 9 months after immigration into switzerland, a 38-year-old male patient from liberia/west africa developed granulomatous and subsequently ulcerative nodules in the face. the heterosexual patient, with no history of i.v. drug abuse, tested positive for hiv-2. histology of a skin biopsy revealed superficial colonization by numerous fungal elements described as spores and hyphae that were compatible with the initial isolation of candida parapsilosis. the definite diagnosis of african histoplasmosis ... | 1996 | 8693301 |
| extracellular proteolytic enzyme activity of histoplasma capsulatum var. duboisii. | histoplasma capsulatum var. duboisii is the etiological agent of african histoplasmosis, an important deep mycosis in west africa. not much is known about the physiological properties of this fungus. this communication reports on the extracellular proteolytic enzyme activity of this fungus. five isolates of this fungus tested hydrolyzed azocasein and bovine serum albumin at ph 6.8 and 8.0. assay of the crude enzyme showed that proteolytic activity increased with age and peaked on the 10th day an ... | 1996 | 8817930 |
| skin and serum reactivity among humans to histoplasmin in the vicinity of a natural focus of histoplasma capsulatum var. duboisii. | the epidemiology of histoplasmosis duboisii (african histoplasmosis) is not well understood. the present study was carried out to investigate the prevalence of skin sensitivity and to determine by immunodiffusion the presence of antibodies among humans to histoplasmin around a recently discovered natural focus of histoplasma capsulatum var. duboisii in a bat cave in ogbunike in the anambra state of nigeria. out of the 40 subjects, all young adults aged 18-30 years, comprising cave guides, trader ... | 1996 | 9011827 |
| in vitro interactions between histoplasma capsulatum var. duboisii and other fungi. | histoplasma capsulatum var. duboisii has only recently been shown to occur naturally in soil admixed with bat guano in a bat cave. we report our observations on the in vitro interaction of histoplasma capsulatum var. duboisii with other fungi recovered from the same habitat or other sources by employing co-culture technique and by investigating antibiosis between h. capsulatum var. duboisii and other fungi. the range of interactions varied from total overgrowth of histoplasma by aspergillus fumi ... | 1997 | 9476515 |
| [apropos of 1 ivoirian case of osseus and cutaneous histoplasmosis by histoplasma capsulatum var. duboisii]. | humeral, tibial and cutaneous localizations of histoplasma capsulatum var. duboisii were observed on a 6 year old boy. the diagnosis was made possible by anatomo-pathological and mycological examinations. treatment with terbinafine was administrated for 4 months. the boy recovered without after-effects in the tibial localization, but did suffer after-effects in the humeral localization. | 1998 | 9642470 |
| [scanning electron microscope sudy of the morphology of fungi isolated from patients at the aristide la dantec hospital in dakar, senegal]. | in order to improve the identification of fungi usually isolated among some patients at dantec hospital, a study by scanning electron microscopy has been carried out. it deals with four species of yeasts (candida albicans, candida parapsilosis, rhodotorula rubra sacharomyces cerevisiae) six species of dermatophytes (trichophyton rubrum, trichophyton soudanense, trichophyton interdigitale, microsporum canis, trichophyton violaceum, microsporum audouinii); two species of mildew, (aspergullus flavu ... | 1996 | 9827085 |
| ribosomal genes of histoplasma capsulatum var. duboisii and var. farciminosum. | a total of 1704 basepairs of the 18s rdna of histoplasma capsulatum var. duboisii (hcd, strain cbs175.57) and h. capsulatum var. farciminosum (hcf, strain cbs478.64) were sequenced (embl accession no. z75306 and no. z75307). the 18s rdna of hcd was 100% identical to a published sequence of h. capsulatum var. capsulatum (hcc). the 18s rdna of hcf showed one transversional point mutation at the nucleotide position 114 (ref. saccharomyces cerevisiae). hybridization confirmed that, in the 18s rdna o ... | 1998 | 9916456 |
| endemic mycoses: a treatment update. | endemic mycoses remain a major public health problem in several countries and they are becoming increasingly frequent with the spread of hiv infection. amphotericin b remains the drug of choice during the acute stage of life-threatening endemic mycoses occurring in both immunocompetent and immunocompromised hosts. ketoconazole is effective in non-aids patients with non-life-threatening histoplasmosis, blastomycosis, or paracoccidioidomycosis. itraconazole is the treatment of choice for non-life- ... | 1999 | 10223586 |
| oral itraconazole therapy for superficial, subcutaneous, and systemic infections. a panoramic view. | the availability of the oral triazole agents itraconazole and fluconazole has revolutionized antifungal therapy. although there are still some limitations and treatment failures, these agents have allowed for improved efficacy, increased safety, reduced morbidity, decreased mortality from systemic fungal disease, and a shift toward increased outpatient therapy for fungal infections that are not life-threatening. the treatment of superficial infections also has been enhanced by the development of ... | 1999 | 10492666 |
| [transmissibility of histoplasma duboisii (human parasitic form) to guinea pig]. | | 1953 | 13092712 |
| [experimental study on a belgian strain of histoplasma capsulatum; comparison with other strains and with histoplasma duboisii]. | | 1956 | 13327875 |
| [culture of histoplasma capsulatum and of histoplasma duboisii on a medium of soil and fecal materials from various animals]. | | 1958 | 13639445 |
| [sabouraudites (microsporum) duboisii vanbreuseghem 1949 and histoplasma duboisii vanbreuseghem 1952]. | | 1964 | 14259261 |
| comparative fluorescent antibody staining of histoplasma capsulatum and histoplasma duboisii with a specific anti-yeast phase h. capsulatum conjugate. | | 1964 | 14285775 |
| histoplasma capsulatum variety duboisii isolated in japan from an hiv-infected ugandan patient. | a strain of histoplasma capsulatum var. duboisii (deposited as ifm 50954 in chiba university) was isolated from the cerebrospinal fluid of a female ugandan patient infected with hiv. the isolate had in vitro urease activity on christensen's urea agar slants, although the common belief is that h. capsulatum var. duboisii is urease negative, and is, considered one of the characteristic markers that distinguishes the three varieties of h. capsulatum. forty h. capsulatum var. capsulatum, five h. cap ... | 2003 | 14615797 |
| accurate diagnosis of infection with histoplasma capsulatum var. duboisii. | | 2004 | 14765358 |
| african histoplasmosis: a review. | african histoplasmosis caused by histoplasma capsulatum var. duboisii is an important deep mycosis endemic in central and west africa and in the island of madagascar. the disease is characterized by presence of granulomatous lesions in the skin, subcutaneous tissues and bones. lungs and other internal organs are rarely involved. the natural reservoir of the etiological agent has only been recently discovered in a bat cave in nigeria. the status of asymptomatic infection is not certain. investiga ... | 1997 | 15538817 |
| [african histoplasmosis (histoplasma capsulatum var. duboisii): a case report from mali]. | we report a case of disseminated african histoplasmosis with lymph node and digestive involvement in a 19-year-old man living in the kayes district of mali. the patient, hiv-seronegative and not otherwise immunocompromised, presented voluminous cervical and axillary adenopathies as well as retrosternal and mesenteric tumor lesions. direct examination of biopsy tissue showed numerous specimens of histoplasma capsulatum var. duboisii. because direct fungal techniques are the easiest and the most e ... | 2005 | 16207583 |
| quantitative studies of total lipids of pathogenic fungi. | ten species of dermatophytes and four of the systemic fungi were assayed for total lipids, acetone-soluble fraction, and phospholipid content in different types of cultures. the yeast phase of each of the systemic fungi grown on solid medium exhibited a higher total lipid content than did the mycelial growth in liquid medium, either shake or still. shake cultures, in all the fungi tested, produced the least lipids. the yeasts were consistently higher also in the acetone-soluble fraction. histopl ... | 1962 | 16349622 |
| hiv infection with concomitant cerebral toxoplasmosis and disseminated histoplasmosis in a 45-year-old man. | although disseminated histoplasmosis is a common opportunistic infection in hiv patients in endemic areas, it is not widely known in japan. we report a rare case of a man from ghana infected with hiv who was hospitalized in japan and who suffered from coinfection with cerebral toxoplasmosis and disseminated histoplasmosis. the diagnosis of cerebral toxoplasmosis was confirmed by a brain biopsy, and the therapy for the disease resulted in almost complete resolution of the brain lesion. however, f ... | 2007 | 17334730 |
| literature review and case histories of histoplasma capsulatum var. duboisii infections in hiv-infected patients. | african histoplasmosis caused by histoplasma capsulatum var. duboisii is an invasive fungal infection endemic in central and west africa. most of its ecology and pathogenesis remain unknown. h. capsulatum var. capsulatum is an aids-defining opportunistic infection in hiv-infected patients who are living in or have traveled to histoplasmosis-endemic areas. in contrast, reports concerning african histoplasmosis during hiv infection are rare, although both pathogens coexist in those regions. we rep ... | 2007 | 18217546 |
| [disseminated cutaneous histoplasmosis due to histoplasma capsulatum var. duboisii associated with aids. a case report in abidjan, côte d'ivoire]. | histoplasmosis is a deep mycosis whose capsulatum variety is recognized as being an aids-defining infection. however aids associated with histoplasma capsulatum var. duboisii is rarely reported. we report a case of cutaneous duboisii histoplasmosis associated with aids which has been mistaken for molluscum contagiosum for many months. the diagnosis has been confirmed by means of a biopsy of a nodule followed by an anatomo-pathological examination. the medical treatment was successfully based on ... | 2008 | 18431996 |
| addison's disease due to histoplasma duboisii infection of the adrenal glands. | histoplasmosis is a fungal infection caused by histoplasma capsulatum. in the normal individual, both disseminated histoplasmosis and symptomatic adrenal histoplasmosis are rare. herein, we describe the case of a 50-year-old gentleman residing in western sudan who presented with a 7-month history of generalized body weakness, easy fatigue, and frequent attacks of vomiting and diarrhea. physical examination and laboratory investigations confirmed the diagnosis of addison's disease due to histopla ... | 2008 | 18521476 |
| disseminated histoplasmosis by histoplasma capsulatum var. duboisii in a paediatric patient from the chad republic, africa. | histoplasmosis caused by histoplasma capsulatum var. duboisii is an endemic mycosis of sub-saharan africa that usually affects the skin, subcutaneous tissue, lymph nodes and bones. we present a case of a 10-year-old immunocompetent girl with severe cutaneous and subcutaneous abscesses affecting the head and upper body. microscopic examination showed polar budding yeasts and short mycelium compatible with h. capsulatum var. duboisii. cultures were not possible but serology showed antibodies again ... | 2009 | 19005708 |
| histoplasma capsulatum var. duboisii infection in a patient with aids: rapid diagnosis using polymerase chain reaction-sequencing. | we describe an original case of disseminated infection with histoplasma capsulatum (hc) var. duboisii in an african patient with aids who migrated to switzerland. the diagnosis of histoplasmosis was suggested using direct examination of tissues and confirmed in 24 h with a panfungal polymerase chain reaction assay. the variety duboisii of hc was established using dna sequencing of the polymorphic genomic region ole. molecular tools allow diagnosis of histoplasmosis in 24 h, which is drastically ... | 2009 | 19304436 |
| pulmonary histoplasmosis presenting as chronic productive cough, fever, and massive unilateral consolidation in a 15-year-old immune-competent boy: a case report. | abstract: | 2011 | 21843324 |
| evaluation of the detection of melanin by the fontana-masson silver stain in tissue with a wide range of organisms including cryptococcus. | it is not uncommon for surgical pathologists to encounter yeast and yeast-like organisms in tissue sections, and correct identification is imperative for guiding therapy. the fontana-masson silver stain for detecting melanin has been accepted as a relatively specific stain for diagnosing cryptococcosis in tissue based on few studies with limited numbers of organisms. this study was designed to test the value of the fontana-masson silver by investigating a large collection of tissues with infecti ... | 2011 | 22154051 |
| [cold thoracic abscess due to histoplasma duboisii. treatment using rifampicin]. | | 2015 | 4360126 |
| disseminated histoplasmosis and secondary hemophagocytic syndrome in a non-hiv patient. | histoplasma duboisii, a variant of histoplasma capsulatum that causes "african histoplasmosis," can be resistant to itraconazole, requiring intravenous amphotericin b treatment. rarely, these patients do not respond to intravenous antifungal therapy, and in such cases, patients may progress to develop secondary hemophagocytic lymphohistiocytosis (hlh). we present a case of a 34-year-old male patient with sickle cell disease who presented with a 5-month history of an enlarging painless axillary m ... | 2015 | 26347828 |
| fungal infection of a ventriculoperitoneal shunt: histoplasmosis diagnosis and treatment. | histoplasmosis is a fungal disease caused by histoplasma capsulatum, commonly found in the americas, and histoplasma duboisii, located in africa. in the united states, h. capsulatum is prevalent in the ohio and mississippi river valleys. in rare circumstances, central nervous system (cns) histoplasmosis infection can be caused by shunt placement. we present a case report of a 45-year-old woman in whom cns histoplasmosis developed after having a ventriculoperitoneal (vp) shunt placed for communic ... | 2016 | 23247021 |
| histoplasma capsulatum infection with extensive lytic bone lesions mimicking lch. | multiple lytic bone lesions in a child can be a manifestation of various diseases like langerhans cell histiocytosis, metastatic neuroblastoma, leukemia, hyperparathyroidism, multifocal osteomyelitis and histoplasmosis. disseminated histoplasmosis caused by histoplasma capsulatum var. duboisii is well known to present with multiple osteolytic lesions in immunocompromised adults and is mostly restricted to the african subcontinent. histoplasmosis seen in american and asian countries is caused by ... | 2016 | 27329388 |
| [aspergillus galactomannan assay for the management of histoplasmosis due to histoplasma capsulatum var. duboisii in hiv-infected patients: education from a clinical case]. | the diagnosis of histoplasmosis due to histoplasma capsulatum var capsulatum is based on a direct examination identifying encapsulated yeast with narrow-based budding. galactomannan antigenemia facilitates diagnosis, as well as the monitoring of patients receiving treatment. the case of a hiv-positive patient from congo-brazzaville with a disseminated form of african histoplasmosis highlighted the positive galactomannan antigen in this disease due to histoplasma capsulatum var duboisii. galactom ... | 2014 | 24636196 |
| disseminated cutaneous histoplasmosis in an immunocompetent adult. | histoplasmosis, a systemic mycosis caused by the dimorphic fungus histoplasma capsulatum var capsulatum and histoplasma capsulatum var duboisii is endemic to many parts of the world. the clinical manifestations range from acute or chronic pulmonary infection to a progressive disseminated disease. after initial exposure to the fungus, the infection is self-limited and restricted to the lungs in 99% of healthy individuals. the remaining 1%, however, progress to either disseminated or chronic disea ... | 2012 | 22707773 |
| [multifocal histoplasmosis due to histoplasma capsulatum var. duboisii in a 22 year-old senegalese patient without proven immunodepression]. | the authors report a case of multifocal african histoplasmosis with polymorphic skin involvement occuring in a patient without proven immunosuppression. he was a young 22-year-old patient from eastern senegal - but born in ouganda - who presented with polymorphic skin lesions: ombilicated papulo-nodules, gums and ulcerative and budding lesions. he showed lymphadenopathies without clinical inflammation and with a cheesy appearance of the biopsy but without tuberculosis and also hepatosplenic and ... | 2016 | 27158080 |
| [nondermatophytic and noncandidal fungi isolated in le dantec university hospital of dakar in 2014: epidemiological, clinical and mycological study]. | in recent years, the incidence of superficial fungal infections involving nondermatophytic and noncandidal fungi increased considerably. the objective of this work was to analyze the epidemiological, clinical and mycological fungal infections due to nondermatophytic and noncandidal fungi diagnosed in the laboratory of parasitology-mycology of le dantec hospital in dakar. with a retrospective study of the various cases of nondermatophytic and noncandidal fungi isolated in the laboratory of parasi ... | 2015 | 26138533 |
| disseminated histoplasmosis caused by histoplasma capsulatum var. duboisii in a non-hiv patient in burkina faso: case report. | histoplasmosis is a fungal infection due to histoplasma capsulatum. the african form of this mycosis, caused by histoplasma capsulatum var. duboisii, remains rare. we report a case of disseminated african histoplasmosis with skin, lymph nodes, bones and viscera localizations. the 22-year-old patient was hiv-seronegative and was considered immunocompetent. the presence of histoplasma capsulatum var duboisii in ulcerations and a nodule pus aspiration was confirmed by direct microscopic examination ... | 2015 | 25840849 |
| african histoplasmosis: the first report of an indigenous case in india. | african histoplasmosis, caused by histoplasma capsulatum var. duboisii, is an invasive fungal infection endemic in central and west africa. cases seen outside africa are generally imported. we report a disseminated purely cutaneous form of this infection in an otherwise healthy person from kerala, in southern india. | 2015 | 25514986 |
| imported african histoplasmosis in an immunocompetent patient 40 years after staying in a disease-endemic area. | histoplasmosis caused by histoplasma capsulatum var. duboisii is a rare disease outside central and western africa. in europe, all cases are imported. we report a case of an african histoplasmosis with isolated pulmonary involvement in a non-immunocompromised patient that occurred 40 years after his stay in a disease-endemic area. the patient was given itraconazole. (18)f-fluoro-2-deoxy-d-glucose positron emission tomography-computed tomography was used to assess evolution during treatment. the ... | 2014 | 25246691 |
| late occurrence of histoplasma duboisii cutaneous and pulmonary infection 18 years after exposure. | we report an imported case of histoplasma capsulatum var. duboisii (h. duboisii) infection in a white french woman revealed by cutaneous lesions of the scalp, 18 years after her last stay in west and central africa. asymptomatic bilateral pulmonary infiltrates were discovered on thoracic computed tomography. skin biopsy allowed the positive diagnosis showing the typical yeasts; culture of biopsy specimens was positive for h. capsulatum. in the absence of criteria of severity, the patient was tre ... | 2014 | 25155354 |
| [disseminated histoplasmosis treated by boluses of fluconazole]. | we report a case in which an hiv-infected man was cured of disseminated histoplasmosis (histoplasma capsulatum var duboisii) after treatment by high-dose fluconazole (1,600 mg taken four times daily) for 2 months, combined with active antiretroviral therapy. the choice of fluconazole at this dosage was motivated by its availability as a generic and thus inexpensive medication, the patient's precarious status, and his critical clinical condition. at the end of the second month of treatment, the p ... | 2016 | 24854365 |
| [malian first observation of disseminated african histoplasmosis with predominant bone localizations in an hiv-negative child in bamako (mali). review of the literature]. | endemic deep fungal infections are still under recognised diseases in daily medical practice because of their rarity in sub-saharan area. the african histoplasmosis histoplasma capsulatum var. duboisii (h. capsulatum duboisii) is the most frequent variety described in mali through limited studies in adult patients, since the first case described by catanei and kervran (1945). our case report is a disseminated histoplasmosis in a young 6-year-old african child. he was male and rural. the infectio ... | 2014 | 24094479 |
| posaconazole as rescue therapy in african histoplasmosis. | african histoplasmosis is a granulomatous mycosis caused by histoplasma capsulatum var. duboisii. treatment is usually extrapolated from guidelines for classical histoplasmosis, and includes 2-4 weeks of amphotericin b followed by a step-down maintenance therapy with itraconazole. pediatric usage of posaconazole, an oral second-generation azole, remains off-label, but recent surveys show that it is safe and well tolerated in children. we report a case of disseminated african histoplasmosis in a ... | 2013 | 23312726 |
| an unusual cutaneous tumor: african histoplasmosis following mudbaths: case report and review. | african histoplasmosis, caused by histoplasma capsulatum var. duboisii, is endemic in africa. the disease usually involves the skin, subcutaneous tissue, and bones. a case of african histoplasmosis presenting as a cutaneous tumor and non-healing wound in a 66-year-old immunocompetent male residing in africa, the first ever reported following mudbaths and acupuncture, is hereby reported. diagnosis was confirmed by means of polymerase chain reaction performed on tissue material. the patient was st ... | 2012 | 22302860 |
| [disseminated histoplasmosis due to histoplasma capsulatum var. duboisii in senegal. a case in hiv-infected patient]. | histoplasmosis, a disease due to histoplasma capsulatum, is an invasive opportunistic fungal infection, endemic in africa. so, the occurrence of african histoplasmosis associated with hiv infection has been rarely reported despite the high prevalence of both pathogens in this area. we report the first case of disseminated african histoplasmosis in an hiv-infected senegalese patient. | 2011 | 24451506 |
| [spondylodiscitis due to histoplasma duboisii. report of two cases and review of the literature]. | we report two cases of african histoplasmosis caused by histoplasma duboisii located in the spine, on two malian adults aged 40 and 47 years respectively. clinical signs consisted of dorsal spinal syndrome in both cases and a paraplegia in one case. radiography and ct scan revealed a spondylodiscitis without any bone reconstruction in both cases and a prevertebral abscess in one case. diagnosis was confirmed by mycological and pathological examinations of surgical specimen which revealed histopl ... | 2001 | 11493872 |
| focal lesion of african histoplasmosis presenting as a malignant gastric ulcer. | we describe the case of a localized lesion of african histoplasmosis, presenting as a gastric ulcer, with radiological and endoscopic features suggesting malignancy, that was submitted to surgery. histologic examination of the resected specimen revealed typical yeasts of histoplasma duboisii. there where no clinical, radiological or endoscopic signs of disseminated disease and conventional antifungal therapy was not prescribed. the patient has been followed for 11 years now, without evidence of ... | 2004 | 8799429 |
| [generalized histoplasmosis due to histoplasma duboisii with mediastino-pulmonary infection. cure after 15 months of treatment with ketoconazole]. | we report a case of a young burkinabian, who presented with the disseminated african form of histoplasmosis, histoplasma duboisii. there was pulmonary mediastinal disease with superficial lymphadenopathy and also hepatic involvement. the diagnosis was achieved by a histological examination of the peripheral glands and micrological examination of the expectorate. a clinical cure (despite the radiological persistence of enlarged but stable left hilar glands) with the follow up 10 months was achiev ... | 1992 | 1439098 |
| african histoplasmosis in a belgian aids patient. | we describe an african histoplasmosis case in a 65-year-old belgian living in zaire for 46 years. microscopic bone marrow examination showed histoplasma. it was confirmed by cultures and hamster inoculation. autopsy revealed a fungal dissemination by histoplasma duboisii. | 2004 | 1922190 |
| a case of african histoplasmosis from sudan. | the first authentic case of african histoplasmosis from the sudan is reported. the patient came from dindir, along the southern part of the blue nile river. he had cutaneous and visceral leishmaniasis as well as the cutaneous form of african histoplasmosis. the latter was proved by culture and histopathology to be due to histoplasma duboisii. the fungus was confined to the skin. h. duboisii may be more prevalent, and further studies in dindir area are needed. | 1988 | 3232196 |
| [histoplasma duboisii osteitis as an imported disease]. | a case of imported histoplasma duboisii osteitis in a visitor from africa to switzerland is described. the diagnosis was by histology confirmed by culture. infection of other organs was ruled out. amphotericin b therapy and its side effects are discussed. | 1987 | 3433083 |
| histoplasma duboisii infection in a liberian girl. | | 1987 | 3562140 |
| [african histoplasmosis in mali]. | twenty-four cases of histoplasmosis have been diagnosed since 1945 in native malians (20 cases) or europeans living in mali (4 cases). seventeen cases have already been published and 7 other cases diagnosed recently in bamako or marseille are reported here. mali is within the african histoplasmosis zone and the kayes district may be a particularly endemic zone. the disease affected the skin (62 p. 100), lymph nodes (46 p. 100), bones (21 p. 100), gastrointestinal tract (26 p. 100) and lungs (4 p ... | 1987 | 3631825 |
| [histoplasmosis caused by histoplasma duboisii]. | | 1985 | 4091417 |
| [disseminated histoplasma duboisii histoplasmosis in a female inhabitant of the ivory coast]. | the authors describe a disseminated multivisceral form of african histoplasmosis due to h. duboisii in a 45 years old black woman. clinical examination shows characteristic lesions of skin, bones and lymph glands. lymphography reveals lesions of deep lymph glands and laparascopy lesions of liver and spleen. first untimely stopped, treatment was started again with ketoconazole. 20 months later, the course of the disease is, as for as we can appreciate it, favourable. | 2013 | 6097790 |
| [african histoplasmosis. a case]. | the case reported concerns a 12 year-old girl, native of the cameroons, hospitalized in france for the treatment of the most severe disseminated type of african histoplasmosis (histoplasma duboisii). in addition to a severe infectious syndrome, the child presented with 3 associated typical involvements: diffuse lymphadenopathy, skin lesions consisting of nodules of the face and trunk and suppurative osteo-articular lesions with an impressive radiological appearance: extensive bone lysis and meta ... | 2016 | 6487046 |
| [histoplasma duboisii histoplasmosis. skin lesions simulating molluscum contagiosum]. | | 1983 | 6660774 |
| primary malignant tumors of bone: incidence in ibadan, nigeria. | an account of primary malignant bone tumors in africans is presented in this series. the study analyzes 170 nigerians with bone neoplasms diagnosed over the 17-year period 1960-1976. it accounted for 1.28 percent of tumors registered in the cancer registry of the university college hospital, ibadan. there were 119 male and 51 female patients, with ages ranging from 4 to 75 years. the most common symptom was painful swelling. trauma was associated with this condition. the pattern of behavior of t ... | 1982 | 6956750 |
| [a disseminated form of histoplasma duboisii histoplasmosis in a zaïre patient (author's transl)]. | report of a case of histoplasmosis observed in zaïre with lymphatic, pulmonary and intestinal localizations. histoplasma duboisii was abundant in the stools, sputum and lymphatic tissue. with no amphotericine b available, treatment first started with high dosage of miconazole which had no effect. ketoconazole have been, then, tried, giving a clinical and biological improvement, but patient still in a very bad condition, died. ketoconazole seems to have a rapid but not lasting effect, even with i ... | 2013 | 6280015 |
| histoplasma duboisii infection of bone. | | 1981 | 7237032 |
| [laryngeal histoplasmosis caused by histoplasma duboisii]. | | 1981 | 7238285 |
| [laryngeal histoplasmosis due to "histoplasma duboisii" (author's transl)]. | primitive detection of the histoplasma duboisii accompanied with proteiform manifestations, is rare in the superior air ways. its localisation at the larynx level is an exception and makes the very interest of our following reported observation. in front of this hard diagnostic, only the pathogenic agent visualisation gives evidence. among serological techniques, immuno-fluorescence and e.l.i.s.a. are very helpful. therapeutic possibilities have been improved by miconazole which both associates ... | 2013 | 7011154 |
| [4 new cases of african histoplasma duboisii histoplasmosis observed in mali]. | | 1979 | 546614 |
| african histoplasmosis in eastern nigeria: report of two culturally proven cases treated with septrin and amphotericin b. | two cases of african histoplasmosis culturally proven to be caused by histoplasma duboisii are reported from eastern nigeria. one case had cutaneous papules and subcutaneous nodules all over his body while the other patient had cutaneous papules, an abscess over the right scapula, enlarged cervical, axillary and inguinal lymph nodes, and possible lung involvement. none of the 35 soil samples collected from the environment of the two patients were found positive for h. duboisii. in the first case ... | 1978 | 731765 |
| [african pulmonary histoplasmosis caused by histoplasma duboisii (1st case in chad)]. | | 1978 | 719827 |
| [a case of african histoplasmosis (histoplasma duboisii)]. | | 2004 | 635402 |
| [african pulmonary histoplasmosis due to histoplasma duboisii]. | | 1977 | 907258 |
| orbital cyst due to histoplasma duboisii. | a cystic swelling in the orbit due to histoplasma duboisii, clinically thought to be a dermoid cyst, is described. | 1977 | 836779 |
| [biochemical studies on the mycelial cell wall of histoplasma duboisii (author's transl)]. | | 1977 | 602600 |
| [systemic histoplasmosis with histoplasma duboisii. miliary pulmonary form with fatal termination]. | | 1974 | 4836474 |
| [peritonitis due to perforation of intestinal histoplasmosis due to histoplasma duboisii]. | | 1972 | 4659561 |
| [imported pathology: african histoplasmosis due to histoplasma duboisii]. | | 2016 | 4266494 |