Publications

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full molecular characterization of a simian immunodeficiency virus, sivwrcpbt from temminck's red colobus (piliocolobus badius temminckii) from abuko nature reserve, the gambia.simian immunodeficiency viruses (sivs) are found in an extensive number of african primates, and humans continue to be exposed to these viruses by hunting and handling of primate bushmeat. the purpose of our study was to examine to what extent piliocolobus badius subspecies are infected with siv in order to better characterize sivwrc in general and to gain further insight into the impact of geographic barriers and subspeciation on the evolution of sivwrc. we analysed sixteen faecal samples and t ...200818442839
characterization of novel simian immunodeficiency viruses from red-capped mangabeys from nigeria (sivrcmng409 and -ng411).two novel simian immunodeficiency virus (siv) strains from wild-caught red-capped mangabeys (cercocebus torquatus torquatus) from nigeria were characterized. sequence analysis of the fully sequenced siv strain rcmng411 (sivrcmng411) and gag and pol sequence of sivrcmng409 revealed that they were genetically most closely related to the recently characterized sivrcm from gabon (sivrcmgb1). thus, red-capped mangabeys from distant geographic locations harbor a common lineage of siv. sivrcmng411 carr ...200111711592
simian immunodeficiency virus (siv) from sun-tailed monkeys (cercopithecus solatus): evidence for host-dependent evolution of siv within the c. lhoesti superspecies.recently we reported the characterization of simian immunodeficiency virus (sivlhoest) from a central african l'hoest monkey (cercopithecus lhoesti lhoesti) that revealed a distant relationship to siv isolated from a mandrill (sivmnd). the present report describes a novel siv (sivsun) isolated from a healthy, wild-caught sun-tailed monkey (cercopithecus lhoesti solatus), another member of the l'hoest superspecies. sivsun replicated in a variety of human t-cell lines and in peripheral blood monon ...199910438863
occurrence and frequency of transmission of naturally occurring simian retroviral infections (siv, stlv, and srv) at the cirmf primate center, gabon.among the primates held at the cirmf primate center, gabon, no serological sign of siv infection could be demonstrated in 68 cynomolgus monkeys, 60 chimpanzees, nine gorillas, and 12 sun-tailed monkeys, while seven of 102 mandrills and six of 24 vervets were infected with siv. six mandrills, seven vervets and ten cynomolgus monkeys exhibited a full htlv type 1 western blot profile. the sera of two gorillas and one chimpanzee presented with a positive but not typical htlv western blot profile. th ...19969029395
the targeted sequencing of alpha satellite dna in cercopithecus pogonias provides new insight into the diversity and dynamics of centromeric repeats in old world monkeys.alpha satellite is the major repeated dna element of primate centromeres. specific evolutionary mechanisms have led to a great diversity of sequence families with peculiar genomic organization and distribution, which have till now been studied mostly in great apes. using high throughput sequencing of alpha satellite monomers obtained by enzymatic digestion followed by computational and cytogenetic analysis, we compare here the diversity and genomic distribution of alpha satellite dna in two rela ...201829860303
clinical biochemistry and hematology of the elusive sun-tailed monkey (cercopithecus solatus) in gabon: inaugural data from the only semifree ranging colony in the world.clinical blood biochemistry and hematology are valuable tools to evaluate health and welfare in many animal species. in order to document the general biology of one of the most poorly known nonhuman primate species, and contribute to its conservation, the clinical blood biochemistry and hematology of the sun-tailed monkey (cercopithecus solatus harrisson) was investigated in its range of endemicity in gabon. data derived from 26 years of clinical monitoring of the only semicaptive colony of this ...201224006542
degree of terrestrial activity of the elusive sun-tailed monkey (cercopithecus solatus) in gabon: comparative study of behavior and postcranial morphometric data.we carried out a multidisciplinary study linking behavioral and morphological data from a little-known guenon species, cercopithecus solatus, endemic to gabon. over a period of 9 months, we documented the pattern of stratum use associated with postural and locomotor behavior by direct observation (650 hrs) of a semi-free-ranging breeding colony. we also conducted a morphometric analysis of the humerus and limb proportions of 90 adult specimens from 16 guenon species, including c. solatus. field ...201526148774
diversity and distribution of alpha satellite dna in the genome of an old world monkey: cercopithecus solatus.alpha satellite is the major repeated dna element of primate centromeres. evolution of these tandemly repeated sequences has led to the existence of numerous families of monomers exhibiting specific organizational patterns. the limited amount of information available in non-human primates is a restriction to the understanding of the evolutionary dynamics of alpha satellite dna.201627842493
full-length genome sequence of a simian immunodeficiency virus from a wild-captured sun-tailed monkey in gabon provides evidence for a species-specific monophyletic sivsun lineage.abstract since the first characterization of sivsun (l14 strain) from a sun-tailed monkey (cercopithecus solatus) in gabon in 1999, no further information exists about the evolutionary history and geographic distribution of this lentivirus. here, we report the full-length molecular characterization of a second sivsun virus (sivsunk08) naturally infecting a wild-caught sun-tailed monkey. the sivsunk08 strain was most closely related to sivsunl14 and clustered with members of the sivmnd-1/sivlhoes ...201121453183
paucity of cd4+ccr5+ t cells is a typical feature of natural siv hosts.in contrast to lentiviral infections of humans and macaques, simian immunodeficiency virus (siv) infection of natural hosts is nonpathogenic despite high levels of viral replication. however, the mechanisms underlying this absence of disease are unknown. here we report that natural hosts for siv infection express remarkably low levels of ccr5 on cd4+ t cells isolated from blood, lymph nodes, and mucosal tissues. given that this immunologic feature is found in 5 different species of natural siv h ...200717003371
a preliminary study on the social relationships in a semi-free ranging colony of sun-tailed monkeys (cercopithecus solatus), a species recently discovered in gabon.in 1984, a species of guenon endemic to gabon was discovered: the sun-tailed monkey (cercopithecus solatus). this species is difficult to locate and observe in the wild, and hence to date has been little studied. the centre international de recherches medicales de franceville (cirmf), gabon, houses the world's only breeding colony of c. solatus, on which eco-ethological investigations can be carried out in a semi-free ranging environment. the data reported here present the first results of obser ...200212082303
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