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effect of culture conditions on antifouling compound production of a sponge-associated fungus.microorganisms associated with invertebrate hosts have long been suggested to be a source for bioactive metabolites. in this study, we reported that a sponge-associated fungus, letendraea helminthicola, produced two antifouling compounds: 3-methyl-n-(2-phenylethyl) butanamide and cyclo(d-pro-d-phe). to optimize the production of these antifouling compounds, we then examined the production of compounds under different culture conditions (temperature, salinity, ph, and carbon and nitrogen sources) ...200717216446
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