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new ribosome-inactivating proteins with polynucleotide:adenosine glycosidase and antiviral activities from basella rubra l. and bougainvillea spectabilis willd.new single-chain (type 1) ribosome-inactivating proteins (rips) were isolated from the seeds of basella rubra l. (two proteins) and from the leaves of bougainvillea spectabilis willd. (one protein). these rips inhibit protein synthesis both in a cell-free system, with an ic50 (concentration causing 50% inhibition) in the 10(-10) m range, and by various cell lines, with ic50s in the 10(-8)-10(-6) m range. all three rips released adenine not only from rat liver ribosomes but also from escherichia ...19979421927
antidiabetic indian plants: a good source of potent amylase inhibitors.diabetes is known as a multifactorial disease. the treatment of diabetes (type ii) is complicated due to the inherent patho-physiological factors related to this disease. one of the complications of diabetes is post-prandial hyperglycemia (pphg). glucosidase inhibitors, particularly α-amylase inhibitors are a class of compounds that helps in managing pphg. six ethno-botanically known plants having antidiabetic property namely, azadirachta indica adr. juss.; murraya koenigii (l.) sprengel; ocimum ...201118955350
bacilliform dna-containing plant viruses in the tropics: commonalities within a genetically diverse group.plant viruses, possessing a bacilliform shape and containing double-stranded dna, are emerging as important pathogens in a number of agricultural and horticultural crops in the tropics. they have been reported from a large number of countries in african and asian continents, as well as from islands from the pacific region. the viruses, belonging to two genera, badnavirus and tungrovirus, within the family caulimoviridae, have genomes displaying a common plan, yet are highly variable, sometimes e ...201323763585
engineering and biological characterization of vb6-845, an anti-epcam immunotoxin containing a t-cell epitope-depleted variant of the plant toxin bouganin.the clinical development of immunotoxins in the treatment of solid tumors has been impeded in part, by the induction of an immune response directed primarily against the toxin moiety. bouganin, a type i ribosome inactivating protein isolated from the leaf of bougainvillea spectabilis willd, was mutated to remove the t-cell epitopes while preserving the biological activity of the wild-type molecule. the t-cell epitope-depleted variant of bouganin (de-bouganin) was genetically linked to an anti-ep ...200919483652
antihyperlipidemic effect of d-pinitol on streptozotocin-induced diabetic wistar rats.d-pinitol (3-o-methyl-chiroinositol), an active principle of the traditional antidiabetic plant, bougainvillea spectabilis, is claimed to exert insulin-like effects. this study was undertaken to evaluate the effect of d-pinitol on lipids and lipoproteins in streptozotocin (stz)-induced diabetic wistar rats. rats were made type ii diabetic by single intraperitoneal injection of stz at a dose of 40 mg/kg body weight. stz-induced diabetic rats showed significant (p < 0.05) increase in the levels of ...200818752266
insulin-like effect of pinitol.d-pinitol (3-o-methyl-chiroinositol), an active principle of the traditional antidiabetic plant bougainvillea spectabilis, is claimed to exert insulin-like effects. this study investigates the effect of d-pinitol on glucose homeostasis in animal models of diabetes, and on glucose transport by cultured muscle cells. plasma glucose concentrations were measured in normal, obese-diabetic (ob/ob) and streptozotocin (stz)-diabetic mice after oral (p.o.) and intraperitoneal (i.p.) administration of d-p ...200010952686
an antiviral protein from bougainvillea spectabilis roots; purification and characterisation.an antiviral protein active against mechanical transmission of tomato spotted wilt virus was identified in the root tissues of bougainvillea spectabilis willd. bougainvillea antiviral protein i (bap i) was purified to apparent homogeneity from the roots of bougainvillea by ammonium sulphate precipitation, cm- and deae-sepharose chromatography and reverse phase hplc. bap i is a highly basic protein (pi value > 8.6) with an mr of 28,000. the n-terminal sequence of bap i showed homology with other ...19989612957
an oxalic acid oxidase in the leaves of bougainvillea spectabilis. 196213978612
evaluation of air pollution phytotoxicity in a seasonally dry tropical urban environment.this study was conducted in the urban environment of varanasi, india, to evaluate the plant responses to urban air pollution. twenty sites were selected in four different zones of the city. at each site, seven woody perennials of same age classes were selected. out of the four zones (i, ii, iii and iv), zone iv was used as a reference (control) zone as it received the minimum pollution input. plant species growing in polluted and control areas were compared with respect to foliar dust load, per ...199424201886
cloning and expression of cdna coding for bouganin.bouganin is a ribosome-inactivating protein that recently was isolated from bougainvillea spectabilis willd. in this work, the cloning and expression of the cdna encoding for bouganin is described. from the cdna, the amino-acid sequence was deduced, which correlated with the primary sequence data obtained by amino-acid sequencing on the native protein. bouganin is synthesized as a pro-peptide consisting of 305 amino acids, the first 26 of which act as a leader signal while the 29 c-terminal amin ...200211895448
color versus bioactivity in the flowers of bougainvillea spectabilis (nyctaginaceae).the methanolic extracts of bougainvillea spectabilis (nyctaginaceae) flowers (five different colors) were screened biologically by performing four bioassays: antibacterial, antifungal, brine shrimp lethality and phytotoxicity. it was observed that the methanolic extract of white flowers was the most biologically active among all tested extracts. the extracts of white, orange and shocking pink flowers inhibit, while the extracts of red and violet flowers promote, the growth of lemna plants. the e ...200515700638
slope variation and population structure of tree species from different ecological groups in south brazil.size structure and spatial arrangement of 13 abundant tree species were determined in a riparian forest fragment in paraná state, south brazil (23°16's and 51°01'w). the studied species were aspidosperma polyneuron müll. arg., astronium graveolens jacq. and gallesia integrifolia (spreng) harms (emergent species); alseis floribunda schott, ruprechtia laxiflora meisn. and bougainvillea spectabilis willd. (shade-intolerant canopy species); machaerium paraguariense hassl, myroxylum peruiferum l. and ...201021562693
the role of catchment vegetation in reducing atmospheric inputs of pollutant aerosols in ganga river.the role of woody perennials in the ganga river basin in modifying the run-off quality as influenced by atmospheric deposition of pollutant aerosols was investigated. the concentration of seven nutrients and eight metals were measured in atmospheric deposits as well as in run-off water under the influence of five woody perennials. nutrient retention was recorded maximum for bougainvillea spectabilis ranged from 4.30 % to 33.70 %. metal retention was recorded highest for ficus benghalensis ranged ...201222527002
antihyperglycemic effect of crude extracts of some egyptian plants and algae.diabetes mellitus is a major global health problem. various plant extracts have proven antidiabetic activity and are considered as promising substitution for antidiabetic drugs. the antihyperglycemic effect of 16 plants and 4 algae, commonly used in egypt for the treatment of diabetes mellitus, was investigated. a diabetes model was induced by intraperitoneal injection of nicotinamide (120 mg/kg body weight [b.wt.]), then streptozotocin (200 mg/kg b.wt.) after 15 min. hydroethanolic extracts (80 ...201424404976
novel analytical method development for some amide group containing drugs using bougainvillea spectabilis bract extracts.to develop and validate a simple, accurate and precise colorimetric method using bougainvillea spectabilis (b. spectabilis) bract color previously not exploited for estimation of amide group containing drugs i.e. lidocaine and ranolazine in pharmaceutical formulations.201425312184
evaluation of anti-inflammatory activity of methanolic extract of leaves of bougainvillea spectabilis in experimental animal models.bougainvillea spectabilis (bs) (family nyctaginaceae) is said to possess hypoglycemic and anti-inflammatory activities in experimental animals. we had set forward to examine the potential anti-inflammatory activities of bs in experimental models of inflammation.201725598630
bougainvillea spectabilis exhibits antihyperglycemic and antioxidant activities in experimental diabetes.the study investigates the effects of aqueous extract of bougainvillea spectabilis leaves on blood glucose, glycosylated hemoglobin, lipid profile, oxidative stress, and on dna damage, if any, as well as on liver and kidney functions in streptozotocin-induced diabetes in wistar rats. daily administration of the aqueous extract of b spectabilis leaves for 28 days resulted in significant reduction in hyperglycemia and hyperlipidemia as evident from restoration of relevant biochemical markers follo ...201626187284
bougainvinones a-h, peltogynoids from the stem bark of purple bougainvillea spectabilis and their cytotoxic activity.eight new peltogynoids, named bougainvinones a-h (1-8), were obtained from the stem bark of bougainvillea spectabilis. their structures were elucidated by means of physical data (1d and 2d nmr, hresims) and single-crystal x-ray crystallographic analyses. the peltogynoids, a rare type of modified flavonoids, are reported for the first time from this species of the genus bougainvillea. all isolated compounds were evaluated for their cytotoxic effects against five cancer cell lines including kb, he ...201626963142
antidiabetic properties of azardiracta indica and bougainvillea spectabilis: in vivo studies in murine diabetes model.diabetes mellitus is a metabolic syndrome characterized by an increase in the blood glucose level. treatment of diabetes is complicated due to multifactorial nature of the disease. azadirachta indica adr. juss and bougainvillea spectabilis are reported to have medicinal values including antidiabetic properties. in the present study using invivo diabetic murine model, a. indica and b. spectabilis chloroform, methanolic and aqueous extracts were investigated for the biochemical parameters importan ...201119389871
is the flower fluorescence relevant in biocommunication?flower fluorescence has been previously proposed as a potential visual signal to attract pollinators. in this work, this point was addressed by quantitatively measuring the fluorescence quantum yield (φ(f)) for flowers of bellis perennis (white, yellow, pink, and purple), ornithogalum thyrsoides (petals and ovaries), limonium sinuatum (white and yellow), lampranthus productus (yellow), petunia nyctaginiflora (white), bougainvillea spectabilis (white and yellow), antirrhinum majus (white and yell ...201020811871
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