| additional notes on species of aspergillus, eurotium and emericella from egyptian desert soil. | aspergillus floriformis, a. pseudodeflectus, eurotium xerophilum (st. con. a. xerophilus) and emericella purpurea (st. con. a. purpureus) are described and illustrated as new species. in addition the morphology of strains identified as aspergillus melleus, a. caespitosus and a. versicolor is discussed. | 1975 | 1082299 |
| fungal products. part xiii. xanthomegnin, viomellin, rubrosulphin, and viopurpurin, pigments from aspergillus sulphureus and aspergillus melleus. | | 1975 | 1169241 |
| some properties of the alkaline proteinase from aspergillus melleus. | seaprose is a semi-alkaline proteinase produced by aspergillus melleus. the aim of our study was to further characterize the properties of this enzyme, particularly looking at its interaction with alpha 1-proteinase inhibitor, the major human plasma proteinase inhibitor. we studied the cleavage of three synthetic peptide substrates induced by seaprose and the inhibitory profile of the enzyme by means of a panel of inhibitors, including alpha 1-proteinase inhibitor. the interaction between seapro ... | 1991 | 1821412 |
| in vitro rheological assessment of mucolytic activity induced by seaprose. | proteolytic enzymes can act on the polymeric structure of the bronchial mucus, shortening the long chain of mucoproteins, dna and other macromolecules, and thus reducing the viscosity of the mucus facilitating its expectoration. seaprose (flaminase, puropharma) belongs to this class and is a proteinase from aspergillus melleus and it is mainly used in traumatology, orthopaedics, gynaecology and pneumology. in the present study the in vitro activity of increasing concentrations (0.25, 0.5, 1%) of ... | 1990 | 2277801 |
| activation of hageman factor and prekallikrein and generation of kinin by various microbial proteinases. | activation of the hageman factor-kallikrein-kinin system by serratial 56-kda proteinase was previously demonstrated (matsumoto, k., yamamoto, t., kamata, t., and maeda, h. (1984) j. biochem. (tokyo) 96, 739-749; kamata, r., yamamoto, t., matsumoto, k., and maeda, h. (1985) infect. immun. 48, 747-753). to investigate whether the activation of the system is specific for 56-kda proteinase or is found similarly with other microbial proteinases, 11 proteinases of microbial origins were studied; the 5 ... | 1989 | 2499581 |
| [preparation of the mycotoxin ochratoxin a for research and diagnostic purposes]. | the following fungal strains were tested for the production of the mycotoxin ochratoxin a: aspergillus melleus (ccm f 802), aspergillus ochraceus (ccm 8002) and aspergillus ochraceus (ccm f 803). the strain aspergillus melleus (ccm f 802) proved to be very suitable for the laboratory preparation of ochratoxin a. the mould was multiplied on a natural substrate for 14 days at the temperature of 28 degrees c and at 100% relative humidity. ochratoxin a was extracted into organic solvents (chloroform ... | 1987 | 3125655 |
| the role of calcium on semi-alkaline proteinase from aspergillus melleus. | | 1985 | 3893767 |
| [studies on aspergillus proteinase. viii. intestinal absorption of the semialkaline proteinase from aspergillus melleus (author's transl)]. | | 1974 | 4478168 |
| [studies on aspergillus proteinase. iv. hydrolysis of protein by semi-alkaline proteinase from aspergillus melleus (studies on enzymes. xlii)]. | | 1969 | 5389574 |
| conditions for production of ochratoxin a by aspergillus species in a synthetic medium. | trace elements were required by aspergillus melleus and a. ochraceus, but not by a. sulphureus, to grow and to elaborate ochratoxin a. the composition of the medium affected the synthesis of the toxin more than the growth of the mycelium. | 1970 | 5440175 |
| [metabolic products of microorganisms. 70. on the effect of carbon source on the synthesis of sideramine of aspergillus melleus yukawa]. | | 1968 | 5709370 |
| [studies on aspergillus proteinase. pueification, crystallization and some properties of alkaline proteinase from aspergillus melleus (studies on enzymes. xxxvii)]. | | 1968 | 5715521 |
| [studies pf aspergillus proteinase. ii. purification, crystallization and some properties of semi-alkaline proteinase from aspergillus melleus (studies on enzymes. 38)]. | | 1968 | 5715522 |
| [studies on aspergillus proteinase. 3. physicochemical properties and amino acid composition of aspergillus melleus proteinases. (studies on enzymes. 39)]. | | 1968 | 5752579 |
| anti-inflammatory activity of a proteolytic enzyme, prozime-10. | prozime-10 (p-10), a proteolytic enzyme extracted from cultured broth of aspergillus melleus, was injected intravenously into rats in dosages of 1--10 mg/kg and was found to alleviate carrageenin edema. thermal denaturation diminished not only the proteolytic activity but also the antiedematous effect. carrageenin-induced granuloma pouches in rats were reduced by p-10 in a dose-dependent manner (1--5 mg/kg). with p=10 (5 mg/kg i.v.), adjuvant arthritis was inhibited by 62% in the primary phase a ... | 1980 | 6157167 |
| anti-inflammatory mechanism of prozime-10, a proteolytic enzyme. | when prozime-10 (p-10), a protease extracted from cultured both of aspergillus melleus, was injected intravenously into anesthetized dogs, plasma acth was increased with a latency of 30 min, and this was followed by remarkable elevation of plasma cortisol in many instances. a similar increase in plasma cortisol was elicited after trypsin and alpha-chymotrypsin were injected. plasma histamine was raised promptly prior to an increase in plasma acth after p-10 in every case. however, in certain cas ... | 1981 | 6275422 |
| autolysis of semi-alkaline proteinase from aspergillus melleus. | | 1984 | 6394164 |
| chemical modification of tryptophan and histidine residues in semi-alkaline proteinase from aspergillus melleus. | | 1984 | 6440716 |
| genetic variants of protease inhibitors against fungal protease and alpha-chymotrypsin from hemolymph of the silkworm, bombyx mori. | many electrophoretic variants of hemolymph inhibitors of proteases from aspergillus melleus and pancreatic alpha-chymotrypsin were found using 126 silkworm strains. six inhibitors of the fungal protease were detected and eight of chymotrypsin; the distribution of inhibitors among japanese, chinese, and european races was investigated. comparison of electrophoretic patterns from f1 hybrids and parents showed that the offspring produce inhibitors of both parental types. segregation in f2 and backc ... | 1984 | 6529439 |
| interactions of alpha-1-antichymotrypsin, alpha-1-proteinase inhibitor, and alpha-2-macroglobulin with the fungal enzyme, seaprose. | the semi-alkaline proteinase (seaprose) from aspergillus melleus has been tested for its ability to either inactivate or form complexes with three human plasma proteinase inhibitors, alpha-2-macroglobulin, alpha-1-antichymotrypsin and alpha-1-proteinase inhibitor. alpha-2-macroglobulin was found to inhibit seaprose, with two mol of enzyme being complexed per mol of inhibitor. however, alpha-1-proteinase inhibitor was rapidly inactivated by the fungal enzyme as a result of cleavage of the inhibit ... | 1994 | 7521171 |
| synthesis of beta-(1-azulenyl)-l-alanine as a potential blue-colored fluorescent tryptophan analog and its use in peptide synthesis. | acetyl-beta-(1-azulenyl)-d,l-alanine has been synthesized in high overall yield by the malonic ester condensation procedure, and the racemate has been enzymatically resolved with acylase i from aspergillus melleus. the enantiomerically pure l-amino acid is of interest as a blue-colored fluorescent tryptophan analog. the bioactivity data of a heptagastrin analog containing it suggests that the planar aromatic azulene moiety may indeed mimic the tryptophan side chain to some extent, and the spectr ... | 2000 | 10759212 |
| highly efficient immobilization of glycosylated enzymes into polyurethane foams. | glycosylated enzymes, including aminoacylase from aspergillus melleus, chloroperoxidase from caldariomyces fumago, and phytase from aspergillus ficuum, were covalently immobilized into polyurethane foams with very high enzyme loadings of up to 0.2 g protein per gram dry foam. the immobilization efficiency (retained activity) ranged from 100% at a low loading to 60% at high loadings. in contrast to many other immobilization methods no leaching of the enzyme from the support took place under the r ... | 2000 | 10992238 |
| ochratoxin production by the aspergillus ochraceus group and aspergillus alliaceus. | ochratoxin a is a toxic and carcinogenic fungal secondary metabolite; its presence in foods is increasingly regulated. various fungi are known to produce ochratoxins, but it is not known which species produce ochratoxins consistently and which species cause ochratoxin contamination of various crops. we isolated fungi in the aspergillus ochraceus group (section circumdati) and aspergillus alliaceus from tree nut orchards, nuts, and figs in california. a total of 72 isolates were grown in potato d ... | 2002 | 11976104 |
| isolation and insecticidal activity of mellamide from aspergillus melleus. | mellamide, a novel indole amide, was isolated from a fermentation of aspergillus melleus using silica gel and high-performance liquid chromatographic methods. this allowed its separation from three known antiparasitic compounds (ochratoxin a, viomellin and xanthomegnin) also present in the potent extract. the structure was elucidated by (1)h, (13)c, cosy, dept, hmqc and hmbc nmr experiments. hr-ftms aided in the molecular weight and formula determination. mellamide showed in vitro insecticidal a ... | 2003 | 12687496 |
| antibiotics from aspergillus melleus. | | 1950 | 15405793 |
| preparation of cross-linked aggregates of aminoacylase from aspergillus melleus by using bovine serum albumin as an inert additive. | the effects of bovine serum albumin (bsa) addition on the cross-linked enzyme aggregates (clea) of aminoacylase from aspergillus melleus (ec 3.5.1.14) were conducted at varying glutaraldehyde to enzyme ratio. after optimization, clea of aminoacylase prepared with 10 mg bsa per 100 mg enzyme retained 82% activity recovery (named clea-e-bsa) whereas clea prepared without bsa retained only 24% activity recovery (named clea-e) due to the low content of amine residues of aminoacylase. compared with f ... | 2010 | 20363123 |
| associations between fungal species and water damaged building materials. | fungal growth in damp or water damaged buildings worldwide is an increasing problem, which has adverse effects on both the occupants and the buildings. air sampling alone in moldy buildings does not reveal the full diversity of fungal species growing on building materials. one aim of this study was to estimate the qualitative and quantitative diversity of fungi growing on damp or water damaged building materials. another was to determine if associations exist between the most commonly found fung ... | 2011 | 21531835 |
| acylase-containing polyurethane coatings with anti-biofilm activity. | due to the prevalence of biofilm-related infections, which are mediated by bacterial quorum sensing, there is a critical need for materials and coatings that resist biofilm formation. we have developed novel anti-biofilm coatings that disrupt quorum sensing in surface-associated bacteria via the immobilization of acylase in polyurethane films. specifically, acylase from aspergillus melleus was covalently immobilized in biomedical grade polyurethane coatings via multipoint covalent immobilization ... | 2016 | 27240552 |
| onychomycosis from aspergillus melleus, a novel pathogen for humans. fungal identification and in vitro drug susceptibility. | | 2015 | 26174422 |
| loss of second and sixth conserved cysteine residues from trypsin inhibitor-like cysteine-rich domain-type protease inhibitors in bombyx mori may induce activity against microbial proteases. | previous studies have indicated that most trypsin inhibitor-like cysteine-rich domain (til)-type protease inhibitors, which contain a single til domain with ten conserved cysteines, inhibit cathepsin, trypsin, chymotrypsin, or elastase. our recent findings suggest that cys(2nd) and cys(6th) were lost from the til domain of the fungal-resistance factors in bombyx mori, bmspi38 and bmspi39, which inhibit microbial proteases and the germination of beauveria bassiana conidia. to reveal the significa ... | 2016 | 27677962 |
| assessment of multi-contaminant exposure in a cancer treatment center: a 2-year monitoring of molds, mycotoxins, endotoxins, and glucans in bioaerosols. | indoor air quality in health care facilities is a major public health concern, particularly for immunocompromised patients who may be exposed to microbiological contaminants such as molds, mycotoxins, endotoxins, and (1,3)-ß-d-glucans. over 2 years, bioaerosols were collected on a monthly basis in a cancer treatment center (centre f. baclesse, normandy, france), characterized from areas where there was no any particular air treatment. results showed the complexity of mycoflora in bioaerosols wit ... | 2017 | 28012082 |
| the effect of anatase and rutile crystallites isolated from titania p25 photocatalyst on growth of selected mould fungi. | antifungal properties of anatase and rutile crystallites isolated from commercial titania p25 photocatalyst were investigated by mycelium growth in the dark and under indoor light. investigated fungi, i.e., pseudallescheria boydii, scedosporium apiospermum, pseudallescheria ellipsoidea, scedosporium aurantiacum, aspergillus versicolor, aspergillus flavus, stachybotrys chartarum, penicillium chrysogenum, aspergillus melleus, were isolated from air and from moisture condensed on walls. anatase and ... | 2015 | 26177513 |
| an efficient and mild access to n-acetyl protected purine nucleosides based on a chemoselective enzymatic hydrolysis. | n-monoacetylated derivatives of ribo- (adenosine, guanosine) and 2'-deoxyribonucleosides (2'-deoxyadenosine and 2'-deoxyguanosine), useful as oligonucleotide building blocks, were obtained in 88-100% by enzymatic chemoselective hydrolysis of the corresponding peracetylated nucleosides. among the tested hydrolases, most satisfactory results were found with acylase i from aspergillus melleus and candida antarctica lipase b. for acylase i, the observed chemoselectivity towards ester hydrolysis, wit ... | 2013 | 23524256 |