| production and characterization of monoclonal antibodies to cervine herpesvirus-1. | fourteen hybridoma cell lines secreting monoclonal antibodies (mab) to cervine herpesvirus-1 (cerhv-1) produced following the fusion of nso myeloma cells with splenocytes of balb/c mice previously immunized with gradient purified cerhv-1 were selected using an indirect enzyme-linked immunosorbent assay (elisa) employing cerhv-1 antigen and tested by the elisa against four other ruminant alphaherpesviruses from cattle (bovine herpesvirus type 1.1 and 1.2) goat (caprine herpesvirus-2) and reindeer ... | 1992 | 1333671 |
| a comparison of serological relationships among five ruminant alphaherpesviruses by elisa. | using enzyme-linked immunosorbent assays the cross reactivity of bovine herpesvirus-1.1, bovine herpesvirus-1.2, caprine herpesvirus-2, cervine (red deer) herpesvirus-1 and rangiferine (reindeer) herpesvirus-1 has been examined using rabbit hyperimmune antisera and convalescent cattle and red deer field sera. significant cross-reactivity among all the five viruses was demonstrated. a detailed analysis showed that: (1) the two bovine herpesviruses are most closely related, (2) the cervine, caprin ... | 1992 | 1605741 |
| recognition of another member of the malignant catarrhal fever virus group: an endemic gammaherpesvirus in domestic goats. | a novel gammaherpesvirus in goats that is herein tentatively designated as caprine herpesvirus-2 was identified based on the sequence of a fragment from the herpesvirus dna polymerase gene. sequence alignment analysis revealed that the virus sequence isolated from goats was 67% identical to the homologous sequence from alcelaphine herpesvirus-1, 71% identical to ovine herpesvirus-2 and 73% identical to a recently recognized herpesvirus causing malignant catarrhal fever in white-tailed deer. comb ... | 2001 | 11125175 |
| detection and multigenic characterization of a novel gammaherpesvirus in goats. | evidence for the existence of a caprine gammaherpesvirus was obtained by analysis of peripheral blood leucocytes of goats with pcr assays that target the herpesvirus genes encoding the glycoprotein b (gb), the dna polymerase (dpol) and the terminase (term) with degenerate and deoxyinosine-substituted primers. a contiguous 3.6 kbp sequence extending from the gb to the dpol gene was then determined with specific primers. all sequences (gb, dpol and term) showed a close relationship with the corres ... | 2001 | 11311431 |
| detection and multigenic characterization of a herpesvirus associated with malignant catarrhal fever in white-tailed deer (odocoileus virginianus) from missouri. | between 1998 and 2001, tissues from four captive white-tailed deer were observed to have histologic lesions of systemic lymphocytic vasculitis. these lesions suggested malignant catarrhal fever, although epizootic hemorrhagic disease and bluetongue were included in the differential diagnosis. initial diagnostic efforts, including virus isolation and reverse transcription-pcr for epizootic hemorrhagic disease virus and bluetongue virus, failed to identify an etiologic agent. however, consensus pr ... | 2002 | 11923350 |
| mural folliculitis and alopecia caused by infection with goat-associated malignant catarrhal fever virus in two sika deer. | two sika deer from a zoo in florida were examined because of chronic hair loss and skin lesions. no common causes of alopecia were identified in either deer. one deer was treated with prednisone, but the condition worsened when the dosage was decreased. both deer were euthanatized after several months because of continued disease. the predominant histologic lesion in skin specimens was granulomatous mural folliculitis. serologic testing and sequencing of fragments produced with a consensus polym ... | 2002 | 12322924 |
| caprine herpesvirus-2-associated malignant catarrhal fever in white-tailed deer (odocoileus virginianus). | a subacute disease presenting primarily as alopecia and weight loss occurred in 2 white-tailed deer (odocoileus virginianus) on farms in minnesota and in texas. a presumptive diagnosis of malignant catarrhal fever (mcf) was made on the basis of histological lesions. antibody against an epitope conserved among the mcf group viruses was detected in the serum of both deer. dna samples from the deer were subjected to a variety of pcr amplifications. alignment of the amplified sequences from the dise ... | 2003 | 12580295 |
| caprine herpesvirus-2 in association with naturally occurring malignant catarrhal fever in captive sika deer (cervus nippon). | three female sika deer from a single captive herd were submitted for postmortem examination over a 139-day period. the first 2 deer submitted were reported to have lost body mass for 20 days to 1 month before euthanasia. one of these deer had diarrhea, the other had a crusting dermatitis on the nasal planum and inner aspects of both pinnae. the third hind did not have any signs of disease before it was found seizuring and was immediately euthanatized. microscopically, all 3 animals had a lymphoc ... | 2003 | 12661731 |
| evidence of three new members of malignant catarrhal fever virus group in muskox (ovibos moschatus), nubian ibex (capra nubiana), and gemsbok (oryx gazella). | six members of the malignant catarrhal fever (mcf) virus group of ruminant rhadinoviruses have been identified to date. four of these viruses are clearly associated with clinical disease: alcelaphine herpesvirus 1 (alhv-1) carried by wildebeest (connochaetes spp.); ovine herpesvirus 2 (ovhv-2), ubiquitous in domestic sheep; caprine herpesvirus 2 (cphv-2), endemic in domestic goats; and the virus of unknown origin found causing classic mcf in white-tailed deer (odocoileus virginianus; mcfv-wtd). ... | 2003 | 14733283 |
| transmission of caprine herpesvirus 2 in domestic goats. | caprine herpesvirus 2 (cphv-2) is a recently recognized gammaherpesvirus that is endemic in domestic goats and has been observed to cause clinical malignant catarrhal fever (mcf) in certain species of deer. in this study, transmission of cphv-2 in goats was examined. a total of 30 kids born to a cphv-2 positive goat herd were selected and divided into two groups: group 1 (n=16) remained in the positive herd; group 2 (n=14) was separated from the herd at 1 week of age after obtaining colostrum. p ... | 2005 | 15795075 |
| malignant catarrhal fever in free-ranging cervids associated with ovhv-2 and cphv-2 dna. | pathologic lesions were summarized in 18 free-ranging cervids (15 moose [alces alces], two roe deer [capreolus capreolus], and one red deer [cervus elaphus]) diagnosed with malignant catarrhal fever (mcf) after examination at the national veterinary institute, oslo 1982-2005. eye lesions (conjunctivitis, corneal opacity, fibrin clots in the anterior eye chamber) were the most frequent gross finding. erosive-ulcerative mucosal lesions in the nose and mouth were also commonly found. histopathology ... | 2006 | 17255446 |
| a possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo (bubalus bubalis) in switzerland. | abstract: | 2011 | 22132808 |
| [investigation of the presence of the etiological agents of malignant catarrhal fever in clinically healthy ruminants in zoological gardens]. | malignant catarrhal fever (mcf) is an infectious disease in even-toed ungulates including domestic cattle and wild living ruminants, which repeatedly also occurred in zoological gardens in europe. the goal of the study presented here was to determine whether wild ruminants--here in the sense of non-domesticated ruminant species in zoological collections--normally not known as carriers of mcf viruses, may carry and shed these viruses and thus might play a possible role as source of infection. to ... | 2015 | 26054228 |
| first report of malignant catarrhal fever in a captive pudu (pudu puda). | a male, six-year-old pudu (pudu puda) from an italian zoo was submitted for postmortem examination after sudden death. necroscopy revealed non-suppurative bronchopneumonia and degeneration of the liver and haemorrhagic lesions of the thymus, pericardium and spleen. microscopically, multifocal perivascular mononuclear cell infiltrates were observed in the kidneys, lungs, spleen, and the portal triads of the liver. histological examination of the brain showed meningitis, vasculitis and perivascula ... | 2015 | 25769443 |
| two different macaviruses, ovine herpesvirus-2 and caprine herpesvirus-2, behave differently in water buffaloes than in cattle or in their respective reservoir species. | the ongoing global spread of "exotic" farm animals, such as water buffaloes, which carry their native sets of viruses, may bear unknown risks for the animals, into whose ecological niches the former are introduced and vice versa. here, we report on the occurrence of malignant catarrhal fever (mcf) on swiss farms, where "exotic" water buffaloes were kept together with "native" animals, i.e. cattle, sheep, and goats. in the first farm with 56 water buffaloes, eight cases of mcf due to ovine herpes ... | 2013 | 24386255 |
| serological survey to determine the occurrence of malignant catarrhal fever infection in the japanese small ruminant population from northern districts. | ovine herpesvirus 2 (ovhv-2) causes sheep-associated malignant catarrhal fever (sa-mcf), and is responsible for economic losses in cattle and other susceptible species around the world. a survey of 154 serum samples from 14 flocks in 3 japanese prefectures (hokkaido, aomori and iwate) was undertaken between 2007 and 2008 to test for antibodies to ovhv-2. ovhv-2 was present in 56 sheep and 2 goats, with 37.66% of samples having a positive reaction using a serum neutralization test. the immune rea ... | 2013 | 23358513 |
| caprine herpesvirus 2-associated malignant catarrhal fever of captive sika deer (cervus nippon) in an intensive management system. | caprine herpesvirus 2 (cphv-2) infection usually induces chronic malignant catarrhal fever (mcf) in sika deer (cervus nippon), with the primary signs of weight loss, dermatitis and alopecia. | 2018 | 29391011 |