| non-tuberculous mycobacteria in south african wildlife: neglected pathogens and potential impediments for bovine tuberculosis diagnosis. | non-tuberculous mycobacteria (ntm) are not only emerging and opportunistic pathogens of both humans and animals, but from a veterinary point of view some species induce cross-reactive immune responses that hamper the diagnosis of bovine tuberculosis (btb) in both livestock and wildlife. little information is available about ntm species circulating in wildlife species of south africa. in this study, we determined the diversity of ntm isolated from wildlife species from south africa as well as bot ... | 2017 | 28194371 |
| molecular identification of mycobacterium species of public health importance in cattle in zimbabwe by 16s rrna gene sequencing. | mycobacterium species are naturally found in the environment as well as in domestic animals such as cattle. so far, more than 150 species of mycobacterium, some of which are pathogenic, have been identified. laboratory isolation, detection and identification of mycobacterium species are therefore critical if human and animal infections are to be controlled. the objective of this study was to identify mycobacterium species isolated in cattle in zimbabwe using 16s ribosomal rna gene amplification ... | 2015 | 26668660 |
| the mycobacterial binuclear iron monooxygenases require a specific chaperonin-like protein for functional expression in a heterologous host. | the mimabcd gene clusters in mycobacterium smegmatis strain mc(2) 155 and mycobacterium goodii strain 12523 encode binuclear iron monooxygenases that oxidize propane and phenol. in this study, we attempted to express each mimabcd gene cluster in a heterologous host. the actinomycetous strain rhodococcus opacus b-4, which is phylogenetically close to mycobacterium, was selected as the host. each mimabcd gene cluster was cloned into the rhodococcus-escherichia coli shuttle vector, ptip-qc2, and th ... | 2013 | 23171424 |
| catalytic function of the mycobacterial binuclear iron monooxygenase in acetone metabolism. | mycobacteria such as mycobacterium smegmatis strain mc(2)155 and mycobacterium goodii strain 12523 are able to grow on acetone and use it as a source of carbon and energy. we previously demonstrated by gene deletion analysis that the mimabcd gene cluster, which encodes a binuclear iron monooxygenase, plays an essential role in acetone metabolism in these mycobacteria. in the present study, we determined the catalytic function of mimabcd in acetone metabolism. whole-cell assays were performed usi ... | 2015 | 26293913 |
| impact of hydrocarbons, pcbs and heavy metals on bacterial communities in lerma river, salamanca, mexico: investigation of hydrocarbon degradation potential. | freshwater contamination usually comes from runoff water or direct wastewater discharges to the environment. this paper presents a case study which reveals the impact of these types of contamination on the sediment bacterial population. a small stretch of lerma river basin, heavily impacted by industrial activities and urban wastewater release, was studied. due to industrial inputs, the sediments are characterized by strong hydrocarbon concentrations, ranging from 2 935 to 28 430μg·kg(-1) of tot ... | 2015 | 25828406 |
| identification of the regulator gene responsible for the acetone-responsive expression of the binuclear iron monooxygenase gene cluster in mycobacteria. | the mimabcd gene cluster encodes the binuclear iron monooxygenase that oxidizes propane and phenol in mycobacterium smegmatis strain mc2 155 and mycobacterium goodii strain 12523. interestingly, expression of the mimabcd gene cluster is induced by acetone. in this study, we investigated the regulator gene responsible for this acetone-responsive expression. in the genome sequence of m. smegmatis strain mc2 155, the mimabcd gene cluster is preceded by a gene designated mimr, which is divergently t ... | 2011 | 21856847 |
| identification of the monooxygenase gene clusters responsible for the regioselective oxidation of phenol to hydroquinone in mycobacteria. | mycobacterium goodii strain 12523 is an actinomycete that is able to oxidize phenol regioselectively at the para position to produce hydroquinone. in this study, we investigated the genes responsible for this unique regioselective oxidation. on the basis of the fact that the oxidation activity of m. goodii strain 12523 toward phenol is induced in the presence of acetone, we first identified acetone-induced proteins in this microorganism by two-dimensional electrophoretic analysis. the n-terminal ... | 2010 | 21183637 |
| achalasia and mycobacterium goodii pulmonary infection. | achalasia is a common adult disorder that rarely manifests in children and infrequently can be associated with pulmonary nontuberculous mycobacteria infections. we describe here the first case of mycobacterium goodii pulmonary infection associated with achalasia in a pediatric patient. heller myotomy with dor fundoplication and 12 months of treatment with ciprofloxacin and doxycycline resulted in complete clinical and radiologic improvement. | 2011 | 21076363 |
| left knee prosthesis-related mycobacterium goodii infection. | non-tuberculous mycobacteria are increasingly being recognized as important human pathogens. we present the case of a 44-year-old non-diabetic male who underwent left total knee arthroplasty for degenerative arthritis after trauma. he developed left knee swelling and progressively worsening pain over the next 4 weeks. he was referred for treatment using whirlpool baths and developed a blister at the surgical incision site. repeated aspirations of the left knee failed to show any growth of organi ... | 2010 | 21071255 |
| panniculitis attributable to mycobacterium goodii in an immunocompetent dog in georgia. | a 5-year-old 38.3-kg (84.5-lb) mixed-breed dog was examined because of acute onset of lethargy and anorexia. four days later, a raised, firm, warm 15 × 10-cm lesion was detected in the right caudal paralumbar area. | 2010 | 21034345 |
| 'emerging' mycobacteria in south africa. | disease can be caused by various species of the genus mycobacterium. a number of reports, both published and unpublished, of rarely reported mycobacteria have surfaced in south africa in the last few years. some unusual hosts have also been involved, causing concern in some quarters.these include reports on mycobacterium goodii in a spotted hyaena (crocuta crocuta), m. xenopi in a ruffed lemur (varecia variegata), m. intracellulare in wild-caught chacma baboons (papio ursinus), the 'dassie bacil ... | 2009 | 20458859 |
| pacemaker surgical site infection caused by mycobacterium goodii. | we describe what we believe to be the first documented case of mycobacterium goodii infection in europe. it is also the second documented report of a pacemaker pocket surgical site infection caused by m. goodii. although rarely involved in such infections, rapidly growing mycobacteria should be recognized during conventional bacteriological investigations and further identified by molecular tools to provide adequate therapy. in the present case, antimicrobial therapy with doxycycline without rem ... | 2009 | 19273649 |
| both fmnh2 and fadh2 can be utilized by the dibenzothiophene monooxygenase from a desulfurizing bacterium mycobacterium goodii x7b. | to investigate the flavin utilization by dibenzothiophene monooxygenase (dszc), dszc of a desulfurizing bacterium mycobacterium goodii x7b was purified from the recombinant escherichia coli. it was shown to be able to utilize either fmnh(2) or fadh(2) when coupled with a flavin reductase that reduces either fmn or fad. sequence analysis indicated that dszc was similar to the c(2) component of p-hydroxyphenylacetate hydroxylase from acinetobacter baumannii, which can use both fadh(2) and fmnh(2) ... | 2009 | 19144512 |
| pacemaker pocket infection due to mycobacterium goodii: case report and review of the literature. | | 2008 | 18306833 |
| pulmonary infection due to mycobacterium goodii in a spotted hyena (crocuta crocuta) from south africa. | we report a case of pyogranulomatous pneumonia due to infection with mycobacterium goodii in an adult female spotted hyena (crocuta crocuta). the lungs of the animal showed consolidated, granulomatous lesions, and they were extensively and severely infiltrated. polymerase chain reaction sequencing of isolated crude lung tissue dna, and boiled lung culture samples, all confirmed that the causative organism was m. goodii, a recently described fast-growing organism closely related to the nonpathoge ... | 2008 | 18263830 |
| biodesulfurization of dbt in tetradecane and crude oil by a facultative thermophilic bacterium mycobacterium goodii x7b. | mycobacterium goodii x7b, a facultative thermophilic bacterium, cleaving the c-s bond of dibenzothiophene via a sulfur-specific pathway, was investigated for dbt in tetradecane and crude oil desulfurization. the extent of growth was improved by fed-batch culture controlled at a constant ph. the total sulfur level of dibenzothiophene in tetradecane, was reduced by 99%, from 200 to 2 ppm within 24h at 40 degrees c. after 72 h treatment, 59% of the total sulfur content in liaoning crude oil was rem ... | 2007 | 16905217 |
| [a case of mycobacterium goodii infection wifh isolation from blood and a pacemaker lead]. | we report a case of blood stream infection due to mycobacterium goodii in a patient who had an implanting pacemaker. the patient injured left thorax where the pacemaker was implanted several days before septicemia. the microorganism was isolated from both blood cultures and leads of the pacemaker. the serial isolates were identified as m. goodii by conventional biochemical methods, tobramycin susceptibility test and 16sr-rna sequencing. this is the first reported case of m. goodii septicemia in ... | 2006 | 16780134 |
| isolation of nontuberculous mycobacteria in zambia: eight case reports. | the isolation of nontuberculous mycobacteria (ntm) raises the question of their clinical significance, especially in an african setting. we found a high percentage of ntm isolated from various specimens, including ones that are normally sterile, among 213 patients in zambia. because tuberculosis can affect all parts of the body, we decided to include patients who had signs and symptoms in any part of the body for more than 2 weeks. most patients had tractus respiratorius (80%) and tractus digest ... | 2005 | 16333092 |
| postcataract endophthalmitis caused by mycobacterium goodii. | this is the first reported case of delayed-onset postcataract endophthalmitis caused by mycobacterium goodii, confirmed by multiple cultures. the patient had uneventful cataract removal by phacoemulsification with implantation of a posterior chamber intraocular lens (iol). one month later, he developed redness, pain, a hypopyon, and a decrease in visual acuity to finger counting in the affected eye. a vitreous biopsy was performed for suspected endophthalmitis; culture results showed rapidly gro ... | 2005 | 16039508 |
| microbial desulfurization of gasoline in a mycobacterium goodii x7b immobilized-cell system. | mycobacterium goodii x7b, which had been primarily isolated as a bacterial strain capable of desulfurizing dibenzothiophene to produce 2-hydroxybiphenyl via the 4s pathway, was also found to desulfurize benzothiophene. the desulfurization product was identified as o-hydroxystyrene by gas chromatography (gc)-mass spectrometry analysis. this strain appeared to have the ability to remove organic sulfur from a broad range of sulfur species in gasoline. when dushanzi straight-run gasoline (dsrg227) c ... | 2005 | 15640198 |
| mycobacterium goodii infections associated with surgical implants at colorado hospital. | from february to october 2003, mycobacterium goodii wound infections were identified among three patients who received surgical implants at a colorado hospital. this report summarizes the investigation of the first reported nosocomial outbreak of m. goodii. increased awareness is needed about the potential for nontuberculous mycobacteria to cause postoperative wound infections. | 2004 | 15504281 |
| mycobacterium goodii infection in a dog with concurrent hyperadrenocorticism. | abstract a 9-year-old boston terrier was diagnosed with multifocal, nodular panniculitis caused by an organism belonging to the mycobacterium smegmatis group by histological evaluation and bacteriological identification. the mycobacterial species was identified by direct gene sequence analysis and confirmed to be mycobacterium goodii. treatment using doxycycline and ciprofloxacin was successfully implemented for the mycobacterial panniculitis over a period of 9 months. concurrent pituitary-depen ... | 2004 | 15500486 |
| hernia repair mesh-associated mycobacterium goodii infection. | we report on a patient with an abdominal wall abscess that developed after an inguinal hernia repair that utilized synthetic mesh. mycobacterium goodii, a recently recognized, rapidly growing mycobacterium related to m. smegmatis, was isolated both from the abdominal wall aspirate and from surgically drained material. infection resolved following thorough debridement, mesh removal, and prolonged antimicrobial therapy. this case report extends our understanding of the spectrum of m. goodii infect ... | 2004 | 15184492 |
| bursitis due to mycobacterium goodii, a recently described, rapidly growing mycobacterium. | we report a case of olecranon bursitis due to mycobacterium goodii in a 60-year-old man. prior to recognition of his infection, he received intrabursal steroids and underwent olecranon bursectomy. his infection was cured with antimicrobial therapy consisting of doxycycline and ciprofloxacin. this case illustrates that previously unrecognized members of the mycobacterium smegmatis group of mycobacteria have pathogenic potential. | 2001 | 11136814 |
| mycobacterium wolinskyi sp. nov. and mycobacterium goodii sp. nov., two new rapidly growing species related to mycobacterium smegmatis and associated with human wound infections: a cooperative study from the international working group on mycobacterial taxonomy. | previous investigations demonstrated three taxonomic groups among 22 clinical isolates of mycobacterium smegmatis. these studies were expanded to 71 clinical isolates, of which 35 (49%) (group 1) were identical to five atcc reference strains including the type strain atcc 19420t. twenty-eight isolates (39%) were group 2, and eight isolates (11%) were group 3. isolates of groups 2 and 3 were most often associated with post-traumatic or post-surgical wound infections including osteomyelitis, were ... | 1999 | 10555330 |
| mycobacterium goodii: an emerging nosocomial pathogen: a case report and review of the literature. | mycobacterium goodii, a rapidly growing nontuberculous mycobacterium, is an emerging pathogen in nosocomial infections. its inherent resistance patterns make it a challenging organism to treat, and delays in identification can lead to poor outcomes. we present a case of cardiac device pocket infection with m. goodii, complicated by both antibiotic resistance and drug reactions that highlight the challenges faced by clinicians trying to eradicate these infections. we also present a brief review o ... | 2017 | 28286403 |
| pacemaker pocket infection due to mycobacterium goodii, a rapidly growing mycobacteria. | a woman aged 74 years with an implanted dual-chamber pacemaker presented with pacemaker site infection after failing empiric antimicrobial therapy. the pathogen was later identified as mycobacterium goodii, a rapidly growing mycobacteria species. the pacemaker was subsequently removed and the patient was treated with oral ciprofloxacin and doxycycline with clinical improvement. in this article, we describe a rare case of pacemaker site infection by m. goodii. | 2017 | 28073877 |
| complete genome sequence of mycobacterium goodii x7b, a facultative thermophilic biodesulfurizing bacterium with industrial potential. | mycobacterium goodii x7b appeared to have the ability to remove organic sulfur from a broad range of sulfur species in gasoline, diesel and crude oils. the predominant properties make it as a potential workhorse for petroleum biodesulfurization process. we sequenced and annotated the whole genome to serve as a basis for further elucidation of the genetic background of this promising strain, and provide opportunities for investigating the metabolic and regulatory mechanisms. | 2015 | 26278197 |
| first case report of infection by mycobacterium wolinskyi after mammoplasty in brazil. | mycobacterium wolinskyi is a rapidly growing mycobacterium, first described in 1999 as a member of the group mycobacterium smegmatis (mycobacterium smegmatis, mycobacterium wolinskyi and mycobacterium goodii). only 19 case reports all over the world have been described on literature, none of them in brazil. on this report, it is described one case of infection after a mammoplasty procedure performed in a private health service in the county of recife, pernambuco, brazil, in 2009. the mycobacteri ... | 2013 | 24470962 |
| a case of mycobacterium goodii prosthetic valve endocarditis in a non-immunocompromised patient: use of 16s rdna analysis for rapid diagnosis. | mycobacterium goodii is a rare cause of significant infection. m. goodii has mainly been associated with lymphadenitis, cellulitis, osteomyelitis, and wound infection. | 2012 | 23151090 |
| verification of frequency in species of nontuberculous mycobacteria in kermanshah drinking water supplies using the pcr-sequencing method. | nontuberculous mycobacteria are habitants of environment, especially in aquatic systems. some of them cause problems in immunodeficient patients. over the last decade, 16s rrna gene sequencing was established in 45 novel species of nontuberculous mycobacteria. experiences revealed that this method underestimates the diversity, but does not distinguish between some of mycobacterium subsp. to recognize emerging rapidly growing mycobacteria and identify their subsp, rpob gene sequencing has been de ... | 2017 | 27668545 |
| mycobacterium goodii endocarditis following mitral valve ring annuloplasty. | mycobacterium goodii is an infrequent human pathogen which has been implicated in prosthesis related infections and penetrating injuries. it is often initially misidentified as a gram-positive rod by clinical microbiologic laboratories and should be considered in the differential diagnosis. | 2017 | 28327156 |