| coatx-ii, a new dimeric lys49 phospholipase a2 from crotalus oreganus abyssus snake venom with bactericidal potential: insights into its structure and biological roles. | snake venoms are rich and intriguing sources of biologically-active molecules that act on target cells, modulating a diversity of physiological functions and presenting promising pharmacological applications. lys49 phospholipase a2 is one of the multifunctional proteins present in these complex secretions and, although catalytically inactive, has a variety of biological activities, including cytotoxic, antibacterial, inflammatory, antifungal activities. herein, a lys49 phospholipase a2, denomina ... | 2016 | 27530662 |
| a novel phospholipase a2 (d49) from the venom of the crotalus oreganus abyssus (north american grand canyon rattlesnake). | currently, crotalus viridis was divided into two species: crotalus viridis and crotalus oreganus. the current classification divides "the old" crotalus viridis into two new and independent species: crotalus viridis (subspecies: viridis and nuntius) and crotalus oreganus (subspecies: abyssus, lutosus, concolor, oreganus, helleri, cerberus, and caliginis). the analysis of a product from cdna (e6d), derived from the gland of a specie crotalus viridis viridis, was found to produce an acid phospholip ... | 2014 | 24707493 |
| vascular effects and electrolyte homeostasis of the natriuretic peptide isolated from crotalus oreganus abyssus (north american grand canyon rattlesnake) venom. | crotalus oreganus abyssus is a rattlesnake that is usually found in the grand canyon, united states of america. knowledge regarding the composition of c. o. abyssus venom is scarce. new natriuretic peptides (nps) have been isolated and characterized from the venoms of members of the crotalinae family. the np family comprises three members, anp (atrial natriuretic peptide), bnp (b-type natriuretic peptide) and cnp (c-type natriuretic peptide), and has an important role in blood pressure regulatio ... | 2012 | 22617223 |