| anisatin modulation of gaba- and pentobarbital-induced enhancement of diazepam binding in rat brain. | anisatin, a pure toxic substance isolated from the seeds of a japanese plant (illicium anisatum) acts as a picrotoxin-like, non-competitive gaba antagonist. anisatin inhibited [3h]diazepam binding enhanced by either gaba or pentobarbital, without affecting the basal specific binding to rat brain membranes. the inhibition of this pentobarbital enhancement was competitive. these actions of anisatin were even more apparent when the binding assays were carried out at 37 degrees c rather than a 0 deg ... | 1982 | 6292798 |
| anisatin modulation of temperature-dependent inhibition [3h]muscimol binding by chloride ion. | we investigated the effects of anisatin, a pure toxic substance isolated from illicium anisatum, and chloride ion on [3h]muscimol binding to rat brain membranes at various temperatures (0-16 degrees c). chloride ion (100 mm) itself slightly inhibited specific [3h]muscimol binding at 0-4 degrees c and this inhibition was more marked at 10 or 16 degrees c than at 0-4 degrees c. anisatin further decreased [3h]muscimol binding inhibited by 100 mm chloride at 16 degrees c without affecting the basal ... | 1983 | 6307484 |
| anisatin, a potent gaba antagonist, isolated from illicium anisatum. | the neuropharmacological properties of anisatin were tested on the frog spinal cord and the crude synaptic membrane from rat brain. anisatin (10(-5) m) reduced the amplitude of dorsal root potentials induced by stimulation of the adjacent dorsal root and presynaptic inhibition of the ventral root reflex. anisatin shifted the dose-response curve for gaba-induced depolarization in the primary afferent terminal to the right and also reduced the maximum response to gaba. [3h]muscimol binding to the ... | 1981 | 6974321 |
| interaction of anisatin with rat brain gamma-aminobutyric acida receptors: allosteric modulation by competitive antagonists. | anisatin, a toxic sesquiterpene isolated from the japanese star anise (illicium anisatum l.), competitively inhibited the specific binding of [3h]4'-ethynyl-4-n-propylbicycloorthobenzoate ([3h]ebob), a non-competitive antagonist of gamma-aminobutyric acid (gaba)a receptors, to rat brain membranes with an ic50 value of 0.43 microm. r 5135, a competitive gaba antagonist, decreased the potency of anisatin in inhibiting [3h]ebob binding in a negatively cooperative manner. two other competitive antag ... | 1999 | 10413298 |
| the water-soluble extract of illicium anisatum stimulates mouse vibrissae follicles in organ culture. | it is well known that reduced blood flow in the scalp is a cause of alopecia. we have shown previously that the extract of illicium anisatum increases subcutaneous blood flow in mice. in the present study, we used an organ culture system to examine whether this extract promoted hair follicle elongation. b6c3hf1 mouse vibrissae follicles were cultured in serum-free medium for 7 days at 31 degrees c. follicles treated with water-soluble (ws) extracts of the leaves, fruits and roots of illicium ani ... | 2004 | 15265014 |
| chemical composition, antioxidant, anti-elastase, and anti-inflammatory activities of illicium anisatum essential oil. | the essential oil of air-dried illicium anisatum (illiciaceae), obtained by hydrodistillation was analyzed by gas chromatography-mass spectrometry (gc-ms). fifty-two components were identified in the essential oil and the main component was eucalyptol (21.8 %). the antioxidant and anti-elastase activities of the essential oil were also investigated; the essential oil exhibited moderate dpph scavenging and anti-elastase activities. to clarify the mechanism of the anti-inflammatory activities of i ... | 2009 | 19819825 |
| new prenylated côéå-côéâ compounds from the twigs of illicium anisatum. | two new prenylated côéå-côéâ compounds, cycloillicinone (1) and 4-allyl-2-methoxy-6-(2-methylbut-3-en-2-yl)phenol (2), were isolated from the twigs of illicium anisatum, and their structures were determined by 2d-nmr methods. cycloillicinone (1) is a unique prenylated côéå-côéâ that is appended with an additional geranyl unit. compound 2 was found to show moderate neurite-outgrowth promoting activity in primary cultured rat cortical neurons at a concentration of 10 -ám. | 2011 | 21720045 |
| symbiotic fungal flora in leaf galls induced by illiciomyia yukawai (diptera: cecidomyiidae) and in its mycangia. | we investigated the association between a gall midge, illiciomyia yukawai, and its symbiotic fungi on japanese star anise, illicium anisatum. the number of fungal species isolated from the galls increased with development of the galls, whereas those from the leaves showed a different trend. botryosphaeria dothidea was dominant in the galls from june to october, and after that phomopsis sp. 1, colletotrichum sp., and pestalotiopsis sp. became dominant. although b. dothidea was not isolated from t ... | 2011 | 22015684 |
| [peculicidal activity of plant essential oils and their based preparations]. | the peculicidal activity of eight plant essential oils in 75% isopropyl alcohol was in vitro investigated. of them, the substances that were most active against lice were tea tree (melaleuca), eucalyptus, neem, citronella (cymbopogon nardus), and clove (syzygium aromaticum) oils; kt50 was not more than 3 minutes on average; kt95 was 4 minutes. after evaporating the solvent, only five (tea tree, cassia, clove, anise (anisum vulgare), and japanese star anise (illicium anisatum) oils) of the eight ... | 2014 | 25296426 |